Xuan-Zheng Shi, MD

  • 785 Citations
  • 18 h-Index
1990 …2019

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2019

Burn-Induced Impairment of Ileal Muscle Contractility Is Associated with Increased Extracellular Matrix Components

Cummins, C. B., Gu, Y., Wang, X., Lin, Y. M., Shi, X. Z. & Radhakrishnan, R. S., Jan 1 2019, (Accepted/In press) In : Journal of Gastrointestinal Surgery.

Research output: Contribution to journalArticle

Central 5-hydroxytryptamine (5-HT) mediates colonic motility by hypothalamus oxytocin-colonic oxytocin receptor pathway

Xi, T. F., Li, D. N., Li, Y. Y., Qin, Y., Wang, H. H., Song, N. N., Zhang, Q., Ding, Y. Q., Shi, X. Z. & Xie, D. P., Jan 15 2019, In : Biochemical and Biophysical Research Communications. 508, 3, p. 959-964 6 p.

Research output: Contribution to journalArticle

2018

Microbiota dysbiosis and its pathophysiological significance in bowel obstruction

Hegde, S., Lin, Y. M., Golovko, G., Khanipov, K., Cong, Y., Savidge, T., Fofanov, Y. & Shi, X. Z., Dec 1 2018, In : Scientific Reports. 8, 1, 13044.

Research output: Contribution to journalArticle

7 Scopus citations

Microsomal Prostaglandin e Synthase-1 Plays a Critical Role in Long-term Motility Dysfunction after Bowel Obstruction

Lin, Y. M., Fu, Y., Hegde, S., Tang, Y., Radhakrishnan, R. & Shi, X-Z., Dec 1 2018, In : Scientific Reports. 8, 1, 8831.

Research output: Contribution to journalArticle

Novel insights into the mechanisms of abdominal pain in obstructive bowel disorders

Shi, X-Z., Lin, Y. & Hegde, S., Jun 8 2018, In : Frontiers in Integrative Neuroscience. 12, 23

Research output: Contribution to journalArticle

Open Access
1 Scopus citations
5 Scopus citations
2017

GABA-producing Bifidobacterium dentium modulates visceral sensitivity in the intestine

Pokusaeva, K., Johnson, C., Luk, B., Uribe, G., Fu, Y., Oezguen, N., Matsunami, R. K., Lugo, M., Major, A., Mori-Akiyama, Y., Hollister, E. B., Dann-Grice, S., Shi, X-Z., Engler, D. A., Savidge, T. & Versalovic, J., Jan 1 2017, In : Neurogastroenterology and Motility. 29, 1, e12904.

Research output: Contribution to journalArticle

47 Scopus citations

Impaired Interoception in a Preclinical Model of Functional Dyspepsia

Winston, J. H., Aguirre, J. E., Shi, X. Z. & Sarna, S. K., Mar 29 2017, (Accepted/In press) In : Digestive Diseases and Sciences. p. 1-11 11 p.

Research output: Contribution to journalArticle

2 Scopus citations

Obituary: Sushil K. Sarna, Ph.D.

Shi, X-Z., Winston, J., Powell, D. & Shaker, R., Apr 29 2017, In : Neurogastroenterology and Motility.

Research output: Contribution to journalArticle

Open Access

Pathogenesis of abdominal pain in bowel obstruction: Role of mechanical stress-induced upregulation of nerve growth factor in gut smooth muscle cells

Lin, Y. M., Fu, Y., Winston, J., Radhakrishnan, R., Sarna, S. K., Huang, L-Y. & Shi, X-Z., Apr 1 2017, In : Pain. 158, 4, p. 583-592 10 p.

Research output: Contribution to journalArticle

18 Scopus citations
2016

Auricular vagal nerve stimulation ameliorates burn-induced gastric dysmotility via sympathetic-COX-2 pathways in rats

Li, H., Yin, J., Zhang, Z., Winston, J., Shi, X-Z. & Chen, J. D. Z., Jan 1 2016, In : Neurogastroenterology and Motility. 28, 1, p. 36-42 7 p.

Research output: Contribution to journalArticle

6 Scopus citations
2015
8 Scopus citations

Genesis of anxiety, depression, and ongoing abdominal discomfort in ulcerative colitis-like colon inflammation

Chen, J., Winston, J. H., Fu, Y., Guptarak, J., Jensen, K. L., Shi, X. Z., Green, T. A. & Sarna, S. K., Jan 1 2015, In : American Journal of Physiology - Regulatory Integrative and Comparative Physiology. 308, 1, p. R18-R27

Research output: Contribution to journalArticle

Genesis of anxiety, depression, and ongoing abdominal discomfort in ulcerative colitis-like colon inflammation

Chen, J., Winston, J., Fu, Y., Guptarak, J., Jensen, K. L., Shi, X-Z., Green, T. & Sarna, S. K., 2015, In : American Journal of Physiology - Heart and Circulatory Physiology. 308, 1, p. R18-R27

Research output: Contribution to journalArticle

30 Scopus citations

Genesis of anxiety, depression, and ongoing abdominal discomfort in ulcerative colitis-like colon inflammation

Chen, J., Winston, J. H., Fu, Y., Guptarak, J., Jensen, K. L., Shi, X. Z., Green, T. A. & Sarna, S. K., Jan 1 2015, In : American Journal of Physiology - Endocrinology and Metabolism. 308, 1, p. R18-R27

Research output: Contribution to journalArticle

2014
7 Scopus citations

Mechanical stress is a pro-inflammatory stimulus in the gut: In vitro, in vivo and ex vivo evidence

Lin, Y. M., Li, F. & Shi, X. Z., Jan 1 2014, In : PloS one. 9, 9, e106242.

Research output: Contribution to journalArticle

12 Scopus citations

Oxytocin decreases colonic motility of cold water stressed rats via oxytocin receptors

Yang, X., Xi, T. F., Li, Y. X., Wang, H. H., Qin, Y., Zhang, J. P., Cai, W. T., Huang, M. T., Shen, J. Q., Fan, X. M., Shi, X. Z. & Xie, D. P., Aug 21 2014, In : World journal of gastroenterology. 20, 31, p. 10886-10894 9 p.

Research output: Contribution to journalArticle

8 Scopus citations
2013

Are Interstitial Cells of Cajal Involved in Mechanical Stress-Induced Gene Expression and Impairment of Smooth Muscle Contractility in Bowel Obstruction?

Wu, C. C., Lin, Y. M., Gao, J., Winston, J. H., Cheng, L. K. & Shi, X. Z., Sep 30 2013, In : PloS one. 8, 9, e76222.

Research output: Contribution to journalArticle

8 Scopus citations
7 Scopus citations
2012

Cellular mechanism of mechanotranscription in colonic smooth muscle cells

Li, F., Lin, Y. M., Sarna, S. K. & Shi, X. Z., Sep 1 2012, In : American Journal of Physiology - Gastrointestinal and Liver Physiology. 303, 5, p. G646-G656

Research output: Contribution to journalArticle

12 Scopus citations

Electroacupuncture alleviates stress-induced visceral hypersensitivity through an opioid system in rats

Zhou, Y. Y., Wanner, N. J., Xiao, Y., Shi, X. Z., Jiang, X. H., Gu, J. G. & Xu, G. Y., Dec 1 2012, In : World journal of gastroenterology. 18, 48, p. 7201-7211 11 p.

Research output: Contribution to journalArticle

26 Scopus citations

Mechano-transcription of COX-2 is a common response to lumen dilation of the rat gastrointestinal tract

Lin, Y. M., Li, F. & Shi, X. Z., Jul 1 2012, In : Neurogastroenterology and Motility. 24, 7, p. 670-e296

Research output: Contribution to journalArticle

9 Scopus citations
16 Scopus citations
2011
49 Scopus citations

Pathophysiology of motility dysfunction in bowel obstruction: Role of stretch-induced COX-2

Shi, X. Z., Lin, Y. M., Powell, D. W. & Sarna, S. K., Jan 1 2011, In : American Journal of Physiology - Gastrointestinal and Liver Physiology. 300, 1, p. G99-G108

Research output: Contribution to journalArticle

36 Scopus citations
2009
24 Scopus citations
7 Scopus citations

Norepinephrine mediates the transcriptional effects of heterotypic chronic stress on colonic motor function

Choudhury, B. K., Shi, X. Z. & Sarna, S. K., Jun 1 2009, In : American Journal of Physiology - Gastrointestinal and Liver Physiology. 296, 6, p. G1238-G1247

Research output: Contribution to journalArticle

29 Scopus citations
2008
19 Scopus citations
2007

A Novel Role of VIP in Colonic Motility Function: Induction of Excitation-Transcription Coupling in Smooth Muscle Cells

Shi, X. Z., Choudhury, B. K., Pasricha, P. J. & Sarna, S. K., Apr 2007, In : Gastroenterology. 132, 4, p. 1388-1400 13 p.

Research output: Contribution to journalArticle

22 Scopus citations
2005

Negative transcriptional regulation of human colonic smooth muscle Ca v1.2 channels by p50 and p65 subunits of nuclear factor-κB

Shi, X. Z., Pazdrak, K., Saada, N., Dai, B., Palade, P. & Sarna, S. K., Nov 2005, In : Gastroenterology. 129, 5, p. 1518-1532 15 p.

Research output: Contribution to journalArticle

59 Scopus citations
44 Scopus citations
2004

G protein-mediated dysfunction of excitation-contraction coupling in ileal inflammation

Shi, X. Z. & Sarna, S. K., Jun 1 2004, In : American Journal of Physiology - Gastrointestinal and Liver Physiology. 286, 6 49-6, p. G899-G905

Research output: Contribution to journalArticle

20 Scopus citations

TNFα suppresses human colonic circular smooth muscle cell contractility by SP1- and NF-κB-mediated induction of ICAM-1

Pazdrak, K., Shi, X. Z. & Sarna, S. K., Oct 2004, In : Gastroenterology. 127, 4, p. 1096-1109 14 p.

Research output: Contribution to journalArticle

43 Scopus citations
2003

NF-κB activation by oxidative stress and inflammation suppresses contractility in colonic circular smooth muscle cells

Shi, X. Z., Lindholm, P. F. & Sarna, S. K., May 1 2003, In : Gastroenterology. 124, 5, p. 1369-1380 12 p.

Research output: Contribution to journalArticle

61 Scopus citations
2000

Impairment of Ca2+ mobilization in circular muscle cells of the inflamed colon

Shi, X. Z. & Sarna, S. K., Feb 1 2000, In : American Journal of Physiology - Gastrointestinal and Liver Physiology. 278, 2 41-2, p. G234-G242

Research output: Contribution to journalArticle

49 Scopus citations
1999
25 Scopus citations
1998

消化道平滑肌胆碱能M受体亚型及其细胞内信息传递机制

Translated title of the contribution: Cholinergic muscarinic receptors and their signal transduction mechanisms in gut smooth muscle cellsQin, XM. & Shi, X-Z., 1998, In : World Chinese Journal of Digestology. 6, 3, p. 274-275 2 p.

Research output: Contribution to journalArticle

1997

Inflammatory modulation of muscarinic receptor activation in canine ileal circular muscle cells

Shi, X. Z. & Sarna, S. K., Jan 1 1997, In : Gastroenterology. 112, 3, p. 864-874 11 p.

Research output: Contribution to journalArticle

41 Scopus citations
1991

胃电记录的研究与应用

Translated title of the contribution: Electrogastrography: Research and ApplicationsShi, X-Z. & Zhang, JJ., 1991, In : Foreign Medical Sciences: Section of Digestive Diseases. 19, 3, p. 146-149 4 p.

Research output: Contribution to journalArticle

1990

狗小肠部分切除对移行性综合肌电的影响

Translated title of the contribution: Effect of Partial Removal of Proximal Small Intestine on Migrating Myoelectric Complexes in DogsYang, YK., Zhang, JJ. & Shi, X-Z., 1990, In : Zhongguo ying yong sheng li xue za zhi = Zhongguo yingyong shenglixue zazhi = Chinese journal of applied physiology. 6, 4, p. 316-319 4 p.

Research output: Contribution to journalArticle

红霉素对狗胃肠道电活动的影响

Translated title of the contribution: Effects of erythromycin on the gastrointestinal myoelectric activity in dogsShi, X-Z., Zhang, JJ. & Yang, YK., 1990, In : Zhongguo ying yong sheng li xue za zhi = Zhongguo yingyong shenglixue zazhi = Chinese journal of applied physiology. 6, 1, p. 50-54 5 p.

Research output: Contribution to journalArticle