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Xuping Xie

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Xuping Xie, PhD

20102026

Research activity per year

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Research Strategic Pillar

The Chief Research Officer, has determined that UTMB research should be prioritized into six health communities. This researcher has received the following badge(s):

Research Strategic Pillar Keywords

  • Infectious/ Immunological Health

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Collaborations and top research areas from the last five years

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View all 22 projects/grants

  • 1′- and 4′-Cyano Modified Adenosine Analogs Against Prototypic Flavivirus RNA-Dependent RNA Polymerases

    Walker, S. M., Gordon, C. J., Tchesnokov, E. P., Sun, L., Zou, J., Xie, X., Riola, N. C., Cutillas, V., Du Pont, V., Zhao, X., Wang, T., Pitts, J., Siegel, D. S., Perry, J. K., Feng, J. Y., Bilello, J. P. & Götte, M., Feb 2026, In: Viruses. 18, 2, 257.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    1   Link opens in a new tab Scopus citations

  • Discovery of EGT710, an Oral Nonpeptidomimetic Reversible Covalent SARS-CoV-2 Main Protease Inhibitor

    Papillon, J. P. N., Yuan, J., Hesse, M. J., Zhang, L., Robinson, R. I., Ware, N. F., Hornak, V., Karki, R. G., Kirrane, T., Garland, K., Joseph, S., Moquin, S. A., Lakshminarayana, S. B., Tandeske, L., Dovala, D., Knapp, M., Ornelas, E., Fuller, D., Ho, P. I. & Xie, X. & 15 others, Vulic, K., Skolnik, S. M., Gao, J., Zambrowski, M., Spiess, M., Duca, J. S., Busby, S. A., Schirle, M., Robinson, M., Shi, P. Y., Moser, H. E., Sarko, C., Bradner, J. E., Diagana, T. T. & Tallarico, J. A., Feb 26 2026, In: Journal of medicinal chemistry. 69, 4, p. 3868-3886 19 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access

  • From nicotine to SARS-CoV-2 antivirals with potent in vivo efficacy and a broad anti-coronavirus spectrum

    Khatua, K., Atla, S., Coleman, D., Blankenship, L. R., Alugubelli, Y. R., Vulupala, V., Guo, X. S., Xia, H., Kalveram, B. K., Walker, D. H., Hurst, B. L., Kumar, S., Cho, C. C. D., Sharma, S., Yang, K., Rabie, D., Nyalata, S., Neuman, B. W., Xie, X. & Xu, S. & 1 others, Liu, W. R., Dec 2026, In: Nature communications. 17, 1, 2782.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    2   Link opens in a new tab Scopus citations

  • Functional and structural basis of Omicron BA.3.2.1 spike

    Wang, Y., Hu, Y., Chen, Z., Zou, J., Zhang, K., Ren, P., Shi, P.-Y., Liang, B. & Xie, X., Aug 25 2026, In: Cell Reports. 45, 8, 117812.

    Research output: Contribution to journal › Article › peer-review

    Open Access

  • HIF1A-dependent induction of alveolar miR-147b dampens SARS-CoV-2-associated ARDS via direct targeting of viral RNA

    Yuan, X., Kim, J., Figarella, K., Wang, Y., Makarevich, O., Ruan, W., Hu, Y., Xie, X., Mills, T., Karmouty-Quintana, H., Chang, C. Y., Mangala, L. S., Rodriguez-Aguayo, C., Amero, P., Tran, T. T., Czopik, A. K., Huang, K., Wang, J., Polverino, F. & Lopez-Berestein, G. & 8 others, Sood, A. K., Potnuru, P., Evans, S. E., Melo, M. F. V., Kheradmand, F., Shi, P.-Y., Liu, H. & Eltzschig, H. K., 2026, (Accepted/In press) In: Anesthesiology.

    Research output: Contribution to journal › Article › peer-review

View all 183 Research outputs