Projects per year
Personal profile
Education/Academic qualification
PhD, Chapel Hill, North Carolina, US
… → 0001
MD, Tianjin, China
… → 0001
Fingerprint Dive into the research topics where Yuhui Yin is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
- 2 Similar Profiles
Mitochondrial DNA
Medicine & Life Sciences
DNA-Directed DNA Polymerase
Medicine & Life Sciences
Tryptophan-tRNA Ligase
Medicine & Life Sciences
Nucleotides
Medicine & Life Sciences
DNA
Medicine & Life Sciences
DNA-Directed RNA Polymerases
Medicine & Life Sciences
Catalytic Domain
Medicine & Life Sciences
Holoenzymes
Medicine & Life Sciences
Network
Recent external collaboration on country level. Dive into details by clicking on the dots.
Projects 2012 2023
Structural Basis for Antiviral Drug Toxicity
National Inst of Allergy & Infectious Di
3/1/18 → 2/28/23
Project: Other project
EL II: Dissecting Dual Function of Pol Gamma in mtDNA Replication and Oxidative Damage Repair
National Inst of General Medical Science
9/1/14 → 8/31/19
Project: Other project
Structural studies of toxicities of inhibitors for HIV-RT to human mitochondrial DNA polymerase
National Inst of General Medical Science
3/1/12 → 2/28/15
Project: Other project
Research Output 1996 2019
- 1061 Citations
- 14 h-Index
- 28 Article
Networked Communication between Polymerase and Exonuclease Active Sites in Human Mitochondrial DNA Polymerase
Sowers, M. L., Anderson, A. P. P., Wrabl, J. O. & Yin, Y. W., Jul 10 2019, In : Journal of the American Chemical Society. 141, 27, p. 10821-10829 9 p.Research output: Contribution to journal › Article
Exonucleases
DNA-Directed DNA Polymerase
Nucleotides
Mitochondrial DNA
Catalytic Domain
Structural insights into the recognition of nucleoside reverse transcriptase inhibitors by HIV-1 reverse transcriptase: First crystal structures with reverse transcriptase and the active triphosphate forms of lamivudine and emtricitabine
Bertoletti, N., Chan, A. H., Schinazi, R. F., Yin, Y. & Anderson, K. S., Jan 1 2019, In : Protein Science. 28, 9, p. 1664-1675 12 p.Research output: Contribution to journal › Article
Reverse Transcriptase Inhibitors
Lamivudine
RNA-Directed DNA Polymerase
Nucleosides
Crystal structure
5
Citations
(Scopus)
PARP1 depletion improves mitochondrial and heart function in Chagas disease: Effects on POLG dependent mtDNA maintenance
Wen, J. J., Yin, Y. & Garg, N., May 1 2018, In : PLoS Pathogens. 14, 5, e1007065.Research output: Contribution to journal › Article
Chagas Disease
Mitochondrial DNA
Maintenance
Trypanosoma cruzi
Cardiac Myocytes
6
Citations
(Scopus)
A domain in human EXOG converts apoptotic endonuclease to DNA-repair exonuclease
Szymanski, M. R., Yu, W., Gmyrek, A. M., White, M., Molineux, I. J., Lee, J. C. & Yin, Y., Jan 1 2017, In : Nature Communications. 8, 14959.Research output: Contribution to journal › Article
Endonucleases
Exonucleases
deoxyribonucleic acid
DNA
Substrates
Erratum: Probing the structural and molecular basis of nucleotide selectivity by human mitochondrial DNA polymerase γ (Proceedings of the National Academy of Sciences of the United States of America (2015) 112 (8596-8601) DOI: 10.1073/pnas.1421733112)
Sohl, C. D., Szymanski, M. R., Mislak, A. C., Shumate, C. K., Amiralaei, S., Schinazi, R. F., Anderson, K. S. & Yin, Y., Feb 2 2016, In : Proceedings of the National Academy of Sciences of the United States of America. 113, 5, p. E662Research output: Contribution to journal › Article