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Yuhui Yin, MD, PhD

  • 1074 Citations
  • 14 h-Index
1996 …2023

Research output per year

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Personal profile

Education/Academic qualification

PhD, Chapel Hill, North Carolina, US

… → 0001

MD, Tianjin, China

… → 0001

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Projects

Structural Basis for Antiviral Drug Toxicity

Yin, Y.

National Inst of Allergy & Infectious Di

3/1/18 → 2/28/23

Project: Other project

EL II: Dissecting Dual Function of Pol Gamma in mtDNA Replication and Oxidative Damage Repair

Yin, Y.

National Inst of General Medical Science

9/1/14 → 8/31/19

Project: Other project

Structural studies of toxicities of inhibitors for HIV-RT to human mitochondrial DNA polymerase

Yin, Y.

National Inst of General Medical Science

3/1/12 → 2/28/15

Project: Other project

Research Output

  • 1074 Citations
  • 14 h-Index
  • 29 Article

Excessive excision of correct nucleotides during DNA synthesis explained by replication hurdles

Singh, A., Pandey, M., Nandakumar, D., Raney, K. D., Yin, Y. W. & Patel, S. S., Jan 1 2020, (Accepted/In press) In : EMBO Journal. e103367.

Research output: Contribution to journal › Article

Open Access

    • Networked Communication between Polymerase and Exonuclease Active Sites in Human Mitochondrial DNA Polymerase

    Sowers, M. L., Anderson, A. P. P., Wrabl, J. O. & Yin, Y. W., Jul 10 2019, In : Journal of the American Chemical Society. 141, 27, p. 10821-10829 9 p.

    Research output: Contribution to journal › Article

    • Structural insights into the recognition of nucleoside reverse transcriptase inhibitors by HIV-1 reverse transcriptase: First crystal structures with reverse transcriptase and the active triphosphate forms of lamivudine and emtricitabine

    Bertoletti, N., Chan, A. H., Schinazi, R. F., Yin, Y. & Anderson, K. S., Jan 1 2019, In : Protein Science. 28, 9, p. 1664-1675 12 p.

    Research output: Contribution to journal › Article

    • 2 Scopus citations

    PARP1 depletion improves mitochondrial and heart function in Chagas disease: Effects on POLG dependent mtDNA maintenance

    Wen, J. J., Yin, Y. & Garg, N., May 1 2018, In : PLoS Pathogens. 14, 5, e1007065.

    Research output: Contribution to journal › Article

    • 7 Scopus citations

    A domain in human EXOG converts apoptotic endonuclease to DNA-repair exonuclease

    Szymanski, M. R., Yu, W., Gmyrek, A. M., White, M., Molineux, I. J., Lee, J. C. & Yin, Y., Jan 1 2017, In : Nature Communications. 8, 14959.

    Research output: Contribution to journal › Article

    • 6 Scopus citations