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Human pregnancy and parturition are fascinating and biologically complex phenomena. Two independent physiological systems, namely the fetus and the mother, co-exist for a defined period of time to maintain pregnancy, aid fetal growth and development.1 This co-existe pregnant uterine tissues2-6. Unfortunately, an unacceptable and growing number of pregnancies do not end at term with a delivery of a fully developed fetus. Approximately 25-30% of the 3.5 million births per year in the United States alone occur in the context of a range of placenta-, fetal membrane-, decidua/myometrium-, and/or cervix (maternal)-mediated adverse pregnancy outcomes such as preterm birth, preeclampsia, small-for-gestational-age birth, gestational diabetes, and others.7-10 Globally, preterm labor and delivery (birth at