Targeting retinoid acid metabolic pathways to treat noise-induced hearing loss

Project: Research project

Project Details

Description

The general aim of this study, in collaboration with Dr. Philippe Diaz, a co-founder of DermaXon, is to identify a novel intervention that can promote the survival of cochlear hair cells and ribbon synapses when administrated before or soon after acoustic trauma by oral delivery. UTMB will perform the following: setting up noise-induced hearing loss animal models, oral application of DX308 to the animals, performing auditory tests, and collecting tissues for morphology analysis.
StatusActive
Effective start/end date1/13/255/31/25

Funding

  • DermaXon ( Award #1R41DC02139401): $90,056.00

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