1H, 13C and 15N NMR assignments of RNA recognizing motifs 1 and 2 of BRUNOL-3 protein from human involved in myotonic dystrophy

Harshesh Bhatt, Kashyap Maruthi, Neel Sarovar Bhavesh

Research output: Contribution to journalArticle

Abstract

BRUNOL-3 protein, an alternate splicing factor, has been known for playing a major role in myotonic dystrophy. It binds to the cTNT m-RNA and prevents splicing of exon-5 region, leading to translation of troponin protein having differential affinity for Ca2+. Here, we report sequence-specific 1H, 13C, and 15N resonance assignments for RNA recognition motifs 1 and 2 of BRUNOL-3 protein.

Original languageEnglish (US)
Pages (from-to)143-145
Number of pages3
JournalBiomolecular NMR Assignments
Volume4
Issue number2
DOIs
StatePublished - Oct 1 2010
Externally publishedYes

Fingerprint

Myotonic Dystrophy
Nucleotide Motifs
Nuclear magnetic resonance
Protein Splicing
RNA
RNA Splicing
Troponin
Alternative Splicing
Protein Biosynthesis
Exons
Proteins
Carbon-13 Magnetic Resonance Spectroscopy
CELF Proteins
RNA Recognition Motif
RNA Splicing Factors

Keywords

  • Alternate splicing factor
  • BRUNOL-3
  • Cardiac troponin T
  • Myotonic dystrophy

ASJC Scopus subject areas

  • Structural Biology
  • Biochemistry

Cite this

1H, 13C and 15N NMR assignments of RNA recognizing motifs 1 and 2 of BRUNOL-3 protein from human involved in myotonic dystrophy. / Bhatt, Harshesh; Maruthi, Kashyap; Bhavesh, Neel Sarovar.

In: Biomolecular NMR Assignments, Vol. 4, No. 2, 01.10.2010, p. 143-145.

Research output: Contribution to journalArticle

@article{883129caa1c543cba2193e382187eef9,
title = "1H, 13C and 15N NMR assignments of RNA recognizing motifs 1 and 2 of BRUNOL-3 protein from human involved in myotonic dystrophy",
abstract = "BRUNOL-3 protein, an alternate splicing factor, has been known for playing a major role in myotonic dystrophy. It binds to the cTNT m-RNA and prevents splicing of exon-5 region, leading to translation of troponin protein having differential affinity for Ca2+. Here, we report sequence-specific 1H, 13C, and 15N resonance assignments for RNA recognition motifs 1 and 2 of BRUNOL-3 protein.",
keywords = "Alternate splicing factor, BRUNOL-3, Cardiac troponin T, Myotonic dystrophy",
author = "Harshesh Bhatt and Kashyap Maruthi and Bhavesh, {Neel Sarovar}",
year = "2010",
month = "10",
day = "1",
doi = "10.1007/s12104-010-9229-6",
language = "English (US)",
volume = "4",
pages = "143--145",
journal = "Biomolecular NMR Assignments",
issn = "1874-2718",
publisher = "Springer Netherlands",
number = "2",

}

TY - JOUR

T1 - 1H, 13C and 15N NMR assignments of RNA recognizing motifs 1 and 2 of BRUNOL-3 protein from human involved in myotonic dystrophy

AU - Bhatt, Harshesh

AU - Maruthi, Kashyap

AU - Bhavesh, Neel Sarovar

PY - 2010/10/1

Y1 - 2010/10/1

N2 - BRUNOL-3 protein, an alternate splicing factor, has been known for playing a major role in myotonic dystrophy. It binds to the cTNT m-RNA and prevents splicing of exon-5 region, leading to translation of troponin protein having differential affinity for Ca2+. Here, we report sequence-specific 1H, 13C, and 15N resonance assignments for RNA recognition motifs 1 and 2 of BRUNOL-3 protein.

AB - BRUNOL-3 protein, an alternate splicing factor, has been known for playing a major role in myotonic dystrophy. It binds to the cTNT m-RNA and prevents splicing of exon-5 region, leading to translation of troponin protein having differential affinity for Ca2+. Here, we report sequence-specific 1H, 13C, and 15N resonance assignments for RNA recognition motifs 1 and 2 of BRUNOL-3 protein.

KW - Alternate splicing factor

KW - BRUNOL-3

KW - Cardiac troponin T

KW - Myotonic dystrophy

UR - http://www.scopus.com/inward/record.url?scp=77958604121&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=77958604121&partnerID=8YFLogxK

U2 - 10.1007/s12104-010-9229-6

DO - 10.1007/s12104-010-9229-6

M3 - Article

VL - 4

SP - 143

EP - 145

JO - Biomolecular NMR Assignments

JF - Biomolecular NMR Assignments

SN - 1874-2718

IS - 2

ER -