Primeiro registro de epidemias causadas pelo vírus Oropouche nos estados do Maranhão e Goiás, Brasil.

Translated title of the contribution: 1st register of an epidemic caused by Oropouche virus in the states of Maranhão and Goiás, Brazil

P. F. Vasconcelos, J. F. Travassos Da Rosa, S. C. Guerreiro, N. Dégallier, E. S. Travassos Da Rosa, A. P. Travassos Da Rosa

Research output: Contribution to journalArticlepeer-review

25 Scopus citations

Abstract

The authors describe the occurrence of outbreaks caused by Oropouche virus (ORO) in the states of Maranhão and Goiás, Brazil in 1988. 36 strains of the virus were obtained from the intracerebral inoculation of the blood of 120 patients into 2-3 day-old infant mice. The illness was characterized by headache, fever, pain in the muscles, joints and back, photophobia, retrobulbar pain, nausea and dizziness. 128 of 197 people examined in Porto Franco, MA, had hemagglutination-inhibiting antibodies to the agent, while 106 of them had IgM antibodies by MAC ELISA test. All age groups were infected, although the incidence was higher among who had 10 to 19 years old. There was no difference, in relation to sex infections. Recurrence of symptoms was reported in 56% of sick people. Mice inoculated with 3624 Culicoides paraensis (Ceratopogonidae) and 1970 Culex (Cux.) quinquefasciatus (Culicidae) collected in Porto Franco resulted in one single isolation of ORO virus, from the Culicoides. These are the first confirmed cases of ORO infection in Maranhão and Goiás states.

Translated title of the contribution1st register of an epidemic caused by Oropouche virus in the states of Maranhão and Goiás, Brazil
Original languagePortuguese
Pages (from-to)271-278
Number of pages8
JournalRevista do Instituto de Medicina Tropical de São Paulo
Volume31
Issue number4
DOIs
StatePublished - 1989

ASJC Scopus subject areas

  • Infectious Diseases

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