2,000 Steps/Day Does Not Fully Protect Skeletal Muscle Health in Older Adults During Bed Rest

Emily Arentson-Lantz, Elfego Galvan, Adam Wacher, Christopher Fry, Douglas Paddon-Jones

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

Physical activity in an inpatient setting is often limited to brief periods of walking. For healthy adults, public health agencies recommend a minimum of 150 min/week of moderate-intensity exercise. The authors sought to determine if meeting this activity threshold, in the absence of incidental activities of daily living, could protect skeletal muscle health during bed rest. Healthy older adults (68 ± 2 years) were randomized to 7-day bed rest with (STEP, n = 7) or without (CON, n = 10) a 2,000 steps/day intervention. Performing 2018 ± 4 steps/day did not prevent the loss of lean leg mass and had no beneficial effect on aerobic capacity, strength, or muscle fiber volume. However, the insulin response to an oral glucose challenge was preserved. Performing a block of 2,000 steps/day, in the absence of incidental activities of daily living, was insufficient to fully counter the catabolic effects of bed rest in healthy older adults.

Original languageEnglish (US)
Pages (from-to)191-197
Number of pages7
JournalJournal of aging and physical activity
Volume27
Issue number2
DOIs
StatePublished - Apr 1 2019

Fingerprint

Bed Rest
Skeletal Muscle
Activities of Daily Living
Health
Exercise
Muscle Strength
Walking
Inpatients
Leg
Public Health
Insulin
Glucose

Keywords

  • atrophy
  • inactivity
  • muscle function
  • physical activity

ASJC Scopus subject areas

  • Physical Therapy, Sports Therapy and Rehabilitation
  • Rehabilitation
  • Gerontology
  • Geriatrics and Gerontology

Cite this

2,000 Steps/Day Does Not Fully Protect Skeletal Muscle Health in Older Adults During Bed Rest. / Arentson-Lantz, Emily; Galvan, Elfego; Wacher, Adam; Fry, Christopher; Paddon-Jones, Douglas.

In: Journal of aging and physical activity, Vol. 27, No. 2, 01.04.2019, p. 191-197.

Research output: Contribution to journalArticle

@article{725c70e89ce44c65977ec91c532018b7,
title = "2,000 Steps/Day Does Not Fully Protect Skeletal Muscle Health in Older Adults During Bed Rest",
abstract = "Physical activity in an inpatient setting is often limited to brief periods of walking. For healthy adults, public health agencies recommend a minimum of 150 min/week of moderate-intensity exercise. The authors sought to determine if meeting this activity threshold, in the absence of incidental activities of daily living, could protect skeletal muscle health during bed rest. Healthy older adults (68 ± 2 years) were randomized to 7-day bed rest with (STEP, n = 7) or without (CON, n = 10) a 2,000 steps/day intervention. Performing 2018 ± 4 steps/day did not prevent the loss of lean leg mass and had no beneficial effect on aerobic capacity, strength, or muscle fiber volume. However, the insulin response to an oral glucose challenge was preserved. Performing a block of 2,000 steps/day, in the absence of incidental activities of daily living, was insufficient to fully counter the catabolic effects of bed rest in healthy older adults.",
keywords = "atrophy, inactivity, muscle function, physical activity",
author = "Emily Arentson-Lantz and Elfego Galvan and Adam Wacher and Christopher Fry and Douglas Paddon-Jones",
year = "2019",
month = "4",
day = "1",
doi = "10.1123/japa.2018-0093",
language = "English (US)",
volume = "27",
pages = "191--197",
journal = "Journal of Aging and Physical Activity",
issn = "1063-8652",
publisher = "Human Kinetics Publishers Inc.",
number = "2",

}

TY - JOUR

T1 - 2,000 Steps/Day Does Not Fully Protect Skeletal Muscle Health in Older Adults During Bed Rest

AU - Arentson-Lantz, Emily

AU - Galvan, Elfego

AU - Wacher, Adam

AU - Fry, Christopher

AU - Paddon-Jones, Douglas

PY - 2019/4/1

Y1 - 2019/4/1

N2 - Physical activity in an inpatient setting is often limited to brief periods of walking. For healthy adults, public health agencies recommend a minimum of 150 min/week of moderate-intensity exercise. The authors sought to determine if meeting this activity threshold, in the absence of incidental activities of daily living, could protect skeletal muscle health during bed rest. Healthy older adults (68 ± 2 years) were randomized to 7-day bed rest with (STEP, n = 7) or without (CON, n = 10) a 2,000 steps/day intervention. Performing 2018 ± 4 steps/day did not prevent the loss of lean leg mass and had no beneficial effect on aerobic capacity, strength, or muscle fiber volume. However, the insulin response to an oral glucose challenge was preserved. Performing a block of 2,000 steps/day, in the absence of incidental activities of daily living, was insufficient to fully counter the catabolic effects of bed rest in healthy older adults.

AB - Physical activity in an inpatient setting is often limited to brief periods of walking. For healthy adults, public health agencies recommend a minimum of 150 min/week of moderate-intensity exercise. The authors sought to determine if meeting this activity threshold, in the absence of incidental activities of daily living, could protect skeletal muscle health during bed rest. Healthy older adults (68 ± 2 years) were randomized to 7-day bed rest with (STEP, n = 7) or without (CON, n = 10) a 2,000 steps/day intervention. Performing 2018 ± 4 steps/day did not prevent the loss of lean leg mass and had no beneficial effect on aerobic capacity, strength, or muscle fiber volume. However, the insulin response to an oral glucose challenge was preserved. Performing a block of 2,000 steps/day, in the absence of incidental activities of daily living, was insufficient to fully counter the catabolic effects of bed rest in healthy older adults.

KW - atrophy

KW - inactivity

KW - muscle function

KW - physical activity

UR - http://www.scopus.com/inward/record.url?scp=85062616907&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85062616907&partnerID=8YFLogxK

U2 - 10.1123/japa.2018-0093

DO - 10.1123/japa.2018-0093

M3 - Article

C2 - 29989486

AN - SCOPUS:85062616907

VL - 27

SP - 191

EP - 197

JO - Journal of Aging and Physical Activity

JF - Journal of Aging and Physical Activity

SN - 1063-8652

IS - 2

ER -