2016 Comprehensive Update of the Banff Working Group on Liver Allograft Pathology: Introduction of Antibody-Mediated Rejection

A. J. Demetris, C. Bellamy, S. G. Hübscher, J. O'Leary, P. S. Randhawa, S. Feng, D. Neil, R. B. Colvin, G. Mccaughan, J. J. Fung, A. Del Bello, F. P. Reinholt, H. Haga, O. Adeyi, A. J. Czaja, T. Schiano, M. I. Fiel, M. L. Smith, M. Sebagh, R. Y. TanigawaF. Yilmaz, G. Alexander, L. Baiocchi, M. Balasubramanian, I. Batal, A. K. Bhan, J. Bucuvalas, C. T S Cerski, F. Charlotte, M. E. de Vera, M. Elmonayeri, P. Fontes, E. E. Furth, A. S H Gouw, S. Hafezi-Bakhtiari, J. Hart, E. Honsova, W. Ismail, T. Itoh, N. C. Jhala, U. Khettry, G. B. Klintmalm, S. Knechtle, T. Koshiba, T. Kozlowski, C. R. Lassman, J. Lerut, J. Levitsky, L. Licini, R. Liotta, G. Mazariegos, M. I. Minervini, J. Misdraji, T. Mohanakumar, J. Mölne, I. Nasser, J. Neuberger, M. O'Neil, O. Pappo, L. Petrovic, P. Ruiz, O. Sağol, A. Sanchez Fueyo, E. Sasatomi, A. Shaked, M. Shiller, T. Shimizu, B. Sis, A. Sonzogni, Heather Stevenson-Lerner, S. N. Thung, G. Tisone, A. C. Tsamandas, A. Wernerson, T. Wu, A. Zeevi, Y. Zen

Research output: Contribution to journalArticle

101 Citations (Scopus)

Abstract

The Banff Working Group on Liver Allograft Pathology reviewed and discussed literature evidence regarding antibody-mediated liver allograft rejection at the 11th (Paris, France, June 5-10, 2011), 12th (Comandatuba, Brazil, August 19-23, 2013), and 13th (Vancouver, British Columbia, Canada, October 5-10, 2015) meetings of the Banff Conference on Allograft Pathology. Discussion continued online. The primary goal was to introduce guidelines and consensus criteria for the diagnosis of liver allograft antibody-mediated rejection and provide a comprehensive update of all Banff Schema recommendations. Included are new recommendations for complement component 4d tissue staining and interpretation, staging liver allograft fibrosis, and findings related to immunosuppression minimization. In an effort to create a single reference document, previous unchanged criteria are also included.

Original languageEnglish (US)
JournalAmerican Journal of Transplantation
DOIs
StateAccepted/In press - 2016

Fingerprint

Allografts
Pathology
Antibodies
Liver
British Columbia
Paris
Liver Cirrhosis
Immunosuppression
France
Canada
Brazil
Guidelines
Staining and Labeling

Keywords

  • Classification systems: Banff classification
  • Clinical research/practice
  • Guidelines
  • Immunosuppression/immune modulation
  • Liver transplantation/hepatology
  • Rejection: antibody-mediated (ABMR)
  • Rejection: T cell mediated (TCMR)
  • Tolerance

ASJC Scopus subject areas

  • Transplantation
  • Immunology and Allergy
  • Pharmacology (medical)

Cite this

2016 Comprehensive Update of the Banff Working Group on Liver Allograft Pathology : Introduction of Antibody-Mediated Rejection. / Demetris, A. J.; Bellamy, C.; Hübscher, S. G.; O'Leary, J.; Randhawa, P. S.; Feng, S.; Neil, D.; Colvin, R. B.; Mccaughan, G.; Fung, J. J.; Del Bello, A.; Reinholt, F. P.; Haga, H.; Adeyi, O.; Czaja, A. J.; Schiano, T.; Fiel, M. I.; Smith, M. L.; Sebagh, M.; Tanigawa, R. Y.; Yilmaz, F.; Alexander, G.; Baiocchi, L.; Balasubramanian, M.; Batal, I.; Bhan, A. K.; Bucuvalas, J.; Cerski, C. T S; Charlotte, F.; de Vera, M. E.; Elmonayeri, M.; Fontes, P.; Furth, E. E.; Gouw, A. S H; Hafezi-Bakhtiari, S.; Hart, J.; Honsova, E.; Ismail, W.; Itoh, T.; Jhala, N. C.; Khettry, U.; Klintmalm, G. B.; Knechtle, S.; Koshiba, T.; Kozlowski, T.; Lassman, C. R.; Lerut, J.; Levitsky, J.; Licini, L.; Liotta, R.; Mazariegos, G.; Minervini, M. I.; Misdraji, J.; Mohanakumar, T.; Mölne, J.; Nasser, I.; Neuberger, J.; O'Neil, M.; Pappo, O.; Petrovic, L.; Ruiz, P.; Sağol, O.; Sanchez Fueyo, A.; Sasatomi, E.; Shaked, A.; Shiller, M.; Shimizu, T.; Sis, B.; Sonzogni, A.; Stevenson-Lerner, Heather; Thung, S. N.; Tisone, G.; Tsamandas, A. C.; Wernerson, A.; Wu, T.; Zeevi, A.; Zen, Y.

In: American Journal of Transplantation, 2016.

Research output: Contribution to journalArticle

Demetris, AJ, Bellamy, C, Hübscher, SG, O'Leary, J, Randhawa, PS, Feng, S, Neil, D, Colvin, RB, Mccaughan, G, Fung, JJ, Del Bello, A, Reinholt, FP, Haga, H, Adeyi, O, Czaja, AJ, Schiano, T, Fiel, MI, Smith, ML, Sebagh, M, Tanigawa, RY, Yilmaz, F, Alexander, G, Baiocchi, L, Balasubramanian, M, Batal, I, Bhan, AK, Bucuvalas, J, Cerski, CTS, Charlotte, F, de Vera, ME, Elmonayeri, M, Fontes, P, Furth, EE, Gouw, ASH, Hafezi-Bakhtiari, S, Hart, J, Honsova, E, Ismail, W, Itoh, T, Jhala, NC, Khettry, U, Klintmalm, GB, Knechtle, S, Koshiba, T, Kozlowski, T, Lassman, CR, Lerut, J, Levitsky, J, Licini, L, Liotta, R, Mazariegos, G, Minervini, MI, Misdraji, J, Mohanakumar, T, Mölne, J, Nasser, I, Neuberger, J, O'Neil, M, Pappo, O, Petrovic, L, Ruiz, P, Sağol, O, Sanchez Fueyo, A, Sasatomi, E, Shaked, A, Shiller, M, Shimizu, T, Sis, B, Sonzogni, A, Stevenson-Lerner, H, Thung, SN, Tisone, G, Tsamandas, AC, Wernerson, A, Wu, T, Zeevi, A & Zen, Y 2016, '2016 Comprehensive Update of the Banff Working Group on Liver Allograft Pathology: Introduction of Antibody-Mediated Rejection', American Journal of Transplantation. https://doi.org/10.1111/ajt.13909
Demetris, A. J. ; Bellamy, C. ; Hübscher, S. G. ; O'Leary, J. ; Randhawa, P. S. ; Feng, S. ; Neil, D. ; Colvin, R. B. ; Mccaughan, G. ; Fung, J. J. ; Del Bello, A. ; Reinholt, F. P. ; Haga, H. ; Adeyi, O. ; Czaja, A. J. ; Schiano, T. ; Fiel, M. I. ; Smith, M. L. ; Sebagh, M. ; Tanigawa, R. Y. ; Yilmaz, F. ; Alexander, G. ; Baiocchi, L. ; Balasubramanian, M. ; Batal, I. ; Bhan, A. K. ; Bucuvalas, J. ; Cerski, C. T S ; Charlotte, F. ; de Vera, M. E. ; Elmonayeri, M. ; Fontes, P. ; Furth, E. E. ; Gouw, A. S H ; Hafezi-Bakhtiari, S. ; Hart, J. ; Honsova, E. ; Ismail, W. ; Itoh, T. ; Jhala, N. C. ; Khettry, U. ; Klintmalm, G. B. ; Knechtle, S. ; Koshiba, T. ; Kozlowski, T. ; Lassman, C. R. ; Lerut, J. ; Levitsky, J. ; Licini, L. ; Liotta, R. ; Mazariegos, G. ; Minervini, M. I. ; Misdraji, J. ; Mohanakumar, T. ; Mölne, J. ; Nasser, I. ; Neuberger, J. ; O'Neil, M. ; Pappo, O. ; Petrovic, L. ; Ruiz, P. ; Sağol, O. ; Sanchez Fueyo, A. ; Sasatomi, E. ; Shaked, A. ; Shiller, M. ; Shimizu, T. ; Sis, B. ; Sonzogni, A. ; Stevenson-Lerner, Heather ; Thung, S. N. ; Tisone, G. ; Tsamandas, A. C. ; Wernerson, A. ; Wu, T. ; Zeevi, A. ; Zen, Y. / 2016 Comprehensive Update of the Banff Working Group on Liver Allograft Pathology : Introduction of Antibody-Mediated Rejection. In: American Journal of Transplantation. 2016.
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T1 - 2016 Comprehensive Update of the Banff Working Group on Liver Allograft Pathology

T2 - Introduction of Antibody-Mediated Rejection

AU - Demetris, A. J.

AU - Bellamy, C.

AU - Hübscher, S. G.

AU - O'Leary, J.

AU - Randhawa, P. S.

AU - Feng, S.

AU - Neil, D.

AU - Colvin, R. B.

AU - Mccaughan, G.

AU - Fung, J. J.

AU - Del Bello, A.

AU - Reinholt, F. P.

AU - Haga, H.

AU - Adeyi, O.

AU - Czaja, A. J.

AU - Schiano, T.

AU - Fiel, M. I.

AU - Smith, M. L.

AU - Sebagh, M.

AU - Tanigawa, R. Y.

AU - Yilmaz, F.

AU - Alexander, G.

AU - Baiocchi, L.

AU - Balasubramanian, M.

AU - Batal, I.

AU - Bhan, A. K.

AU - Bucuvalas, J.

AU - Cerski, C. T S

AU - Charlotte, F.

AU - de Vera, M. E.

AU - Elmonayeri, M.

AU - Fontes, P.

AU - Furth, E. E.

AU - Gouw, A. S H

AU - Hafezi-Bakhtiari, S.

AU - Hart, J.

AU - Honsova, E.

AU - Ismail, W.

AU - Itoh, T.

AU - Jhala, N. C.

AU - Khettry, U.

AU - Klintmalm, G. B.

AU - Knechtle, S.

AU - Koshiba, T.

AU - Kozlowski, T.

AU - Lassman, C. R.

AU - Lerut, J.

AU - Levitsky, J.

AU - Licini, L.

AU - Liotta, R.

AU - Mazariegos, G.

AU - Minervini, M. I.

AU - Misdraji, J.

AU - Mohanakumar, T.

AU - Mölne, J.

AU - Nasser, I.

AU - Neuberger, J.

AU - O'Neil, M.

AU - Pappo, O.

AU - Petrovic, L.

AU - Ruiz, P.

AU - Sağol, O.

AU - Sanchez Fueyo, A.

AU - Sasatomi, E.

AU - Shaked, A.

AU - Shiller, M.

AU - Shimizu, T.

AU - Sis, B.

AU - Sonzogni, A.

AU - Stevenson-Lerner, Heather

AU - Thung, S. N.

AU - Tisone, G.

AU - Tsamandas, A. C.

AU - Wernerson, A.

AU - Wu, T.

AU - Zeevi, A.

AU - Zen, Y.

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KW - Guidelines

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KW - Rejection: T cell mediated (TCMR)

KW - Tolerance

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