2016 comprehensive update of the Banff working group on liver allograft pathology: Introduction of antibody-mediated rejection

A. Jake Demetris, C. Bellamy, S. G. Hübscher, J. O’Leary, P. S. Randhawa, S. Feng, D. Neil, R. B. Colvin, G. McCaughan, J. J. Fung, A. Del Bello, F. P. Reinholt, H. Haga, O. Adeyi, A. J. Czaja, T. Schiano, M. I. Fiel, M. L. Smith, M. Sebagh, R. Y. TanigawaF. Yilmaz, G. Alexander, L. Baiocchi, M. Balasubramanian, I. Batal, A. K. Bhan, J. Bucuvalas, C. T.S. Cerski, F. Charlotte, M. E. De Vera, M. Elmonayeri, P. Fontes, E. E. Furth, A. S.H. Gouw, S. Hafezi-Bakhtiari, J. Hart, E. Honsova, W. Ismail, T. Itoh, N. C. Jhala, U. Khettry, G. B. Klintmalm, S. Knechtle, T. Koshiba, T. Kozlowski, C. R. Lassman, J. Lerut, J. Levitsky, L. Licini, R. Liotta, G. Mazariegos, M. I. Minervini, J. Misdraji, T. Mohanakumar, J. Mölne, I. Nasser, J. Neuberger, M. O’Neil, O. Pappo, L. Petrovic, P. Ruiz, Saǧol, A. Sanchez Fueyo, E. Sasatomi, A. Shaked, M. Shiller, T. Shimizu, B. Sis, A. Sonzogni, H. L. Stevenson, S. N. Thung, G. Tisone, A. C. Tsamandas, A. Wernerson, T. Wu, A. Zeevi, Y. Zen

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423 Scopus citations


The Banff Working Group on Liver Allograft Pathology reviewed and discussed literature evidence regarding antibody-mediated liver allograft rejection at the 11th (Paris, France, June 5–10, 2011), 12th (Comandatuba, Brazil, August 19–23, 2013), and 13th (Vancouver, British Columbia, Canada, October 5–10, 2015) meetings of the Banff Conference on Allograft Pathology. Discussion continued online. The primary goal was to introduce guidelines and consensus criteria for the diagnosis of liver allograft antibodymediated rejection and provide a comprehensive update of all Banff Schema recommendations. Included are new recommendations for complement component 4d tissue staining and interpretation, staging liver allograft fibrosis, and findings related to immunosuppression minimization. In an effort to create a single reference document, previous unchanged criteria are also included.

Original languageEnglish (US)
Pages (from-to)2816-2835
Number of pages20
JournalAmerican Journal of Transplantation
Issue number10
StatePublished - Oct 1 2016

ASJC Scopus subject areas

  • Immunology and Allergy
  • Transplantation
  • Pharmacology (medical)


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