47,XYY and 46,XY males with antisocial and/or sex-offending behavior: antiandrogen therapy plus counseling

J. Money; C. Wiedeking; P. Walker; C. Migeon; W. Meyer; D. Borgaonkar

doi:10.1016/0306-4530(75)90008-6

47,XYY and 46,XY males with antisocial and/or sex-offending behavior: antiandrogen therapy plus counseling

J. Money, C. Wiedeking, P. Walker, C. Migeon, W. Meyer, D. Borgaonkar

Research output: Contribution to journal › Article › peer-review

38 Scopus citations

Abstract

(1) Thirteen males with the 47,XYY genotype and ten with 46,XY were given the androgendepleting (antiandrogenic) steroid, medroxyprogesterone acetate, in combination with a counseling program. (2) Those with the XY genotype were all sex offenders and those with the XYY genotype were antisocial offenders (primarily robbery and destructiveness), with or without sexual offences. (3) The combined treatment program was beneficial in helping sex offenders to regulate their behavior and, in five instances (three XY and two XYY), there was a remission of paraphiliac symptoms. (4) The effect of treatment on aggressive-destructive antisocial behavior was less clear, and was probably due to a placebo-like response.

Original language	English (US)
Pages (from-to)	165-178
Number of pages	14
Journal	Psychoneuroendocrinology
Volume	1
Issue number	2
DOIs	https://doi.org/10.1016/0306-4530(75)90008-6
State	Published - 1975
Externally published	Yes

ASJC Scopus subject areas

Endocrinology, Diabetes and Metabolism
Endocrinology
Endocrine and Autonomic Systems
Psychiatry and Mental health
Biological Psychiatry

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10.1016/0306-4530(75)90008-6

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abstract = "(1) Thirteen males with the 47,XYY genotype and ten with 46,XY were given the androgendepleting (antiandrogenic) steroid, medroxyprogesterone acetate, in combination with a counseling program. (2) Those with the XY genotype were all sex offenders and those with the XYY genotype were antisocial offenders (primarily robbery and destructiveness), with or without sexual offences. (3) The combined treatment program was beneficial in helping sex offenders to regulate their behavior and, in five instances (three XY and two XYY), there was a remission of paraphiliac symptoms. (4) The effect of treatment on aggressive-destructive antisocial behavior was less clear, and was probably due to a placebo-like response.",

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AU - Migeon, C.

AU - Meyer, W.

AU - Borgaonkar, D.

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47,XYY and 46,XY males with antisocial and/or sex-offending behavior: antiandrogen therapy plus counseling

Abstract

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