7,N,N-Trimethyltryptamine (TMT) was synthesized and evaluated as an inhibitor of synaptosomal biogenic amine uptake in rat forebrain homogenates. In addition to inhibiting 3H-serotonin uptake (IC50=0.4 μm). TMT appears to be quite selective and is much less potent in blocking either 3H-norepinephrine or 3H-dopamine uptake (IC50=180 μM and 61 μM, respectively).
|Original language||English (US)|
|Number of pages||4|
|Journal||Research Communications in Chemical Pathology and Pharmacology|
|State||Published - 1978|
ASJC Scopus subject areas
- Pathology and Forensic Medicine
- Pharmacology, Toxicology and Pharmaceutics(all)