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  • Alexander Freiberg
2015

Bolstering Components of the Immune Response Compromised by Prior Exposure to Adenovirus: Guided Formulation Development for a Nasal Ebola Vaccine

Choi, J. H., Schafer, S. C., Freiberg, A. & Croyle, M. A., Aug 3 2015, In : Molecular Pharmaceutics. 12, 8, p. 2697-2711 15 p.

Research output: Contribution to journalArticle

4 Scopus citations
2012

Recent progress in henipavirus research: Molecular biology, genetic diversity, animal models

Rockx, B., Winegar, R. & Freiberg, A. N., Aug 1 2012, In : Antiviral research. 95, 2, p. 135-149 15 p.

Research output: Contribution to journalReview article

33 Scopus citations

Mutational analysis of positively charged amino acid residues of Uukuniemi phlebovirus nucleocapsid protein

Katz, A., Freiberg, A. N., Backström, V., Holm, L., Vaheri, A., Flick, R. & Plyusnin, A., Jul 1 2012, In : Virus Research. 167, 1, p. 118-123 6 p.

Research output: Contribution to journalArticle

1 Scopus citations
2019

SAR studies of 4-acyl-1,6-dialkylpiperazin-2-one arenavirus cell entry inhibitors

Plewe, M. B., Whitby, L. R., Naik, S., Brown, E. R., Sokolova, N. V., Gantla, V. R., York, J., Nunberg, J. H., Zhang, L., Kalveram, B., Freiberg, A. N., Boger, D. L., Henkel, G. & McCormack, K., Jan 1 2019, (Accepted/In press) In : Bioorganic and Medicinal Chemistry Letters. 126620.

Research output: Contribution to journalArticle

2013

Virus nomenclature below the species level: A standardized nomenclature for laboratory animal-adapted strains and variants of viruses assigned to the family Filoviridae

Kuhn, J. H., Bao, Y., Bavari, S., Becker, S., Bradfute, S., Brister, J. R., Bukreyev, A. A., Caì, Y., Chandran, K., Davey, R. A., Dolnik, O., Dye, J. M., Enterlein, S., Gonzalez, J. P., Formenty, P., Freiberg, A. N., Hensley, L. E., Honko, A. N., Ignatyev, G. M., Jahrling, P. B. & 30 others, Johnson, K. M., Klenk, H. D., Kobinger, G., Lackemeyer, M. G., Leroy, E. M., Lever, M. S., Lofts, L. L., Mühlberger, E., Netesov, S. V., Olinger, G. G., Palacios, G., Patterson, J. L., Paweska, J. T., Pitt, L., Radoshitzky, S. R., Ryabchikova, E. I., Saphire, E. O., Shestopalov, A. M., Smither, S. J., Sullivan, N. J., Swanepoel, R., Takada, A., Towner, J. S., van der Groen, G., Volchkov, V. E., Wahl-Jensen, V., Warren, T. K., Warfield, K. L., Weidmann, M. & Nichol, S. T., Jun 1 2013, In : Archives of virology. 158, 6, p. 1425-1432 8 p.

Research output: Contribution to journalArticle

38 Scopus citations
2012

A single sublingual dose of an adenovirus-based vaccine protects against lethal ebola challenge in mice and guinea pigs

Choi, J. H., Schafer, S. C., Zhang, L., Kobinger, G. P., Juelich, T., Freiberg, A. N. & Croyle, M. A., Jan 1 2012, In : Molecular Pharmaceutics. 9, 1, p. 156-167 12 p.

Research output: Contribution to journalArticle

35 Scopus citations
2013

Rift valley fever virus MP-12 vaccine encoding toscana virus NSs retains neuroinvasiveness in mice

Indran, S. V., Lihoradova, O. A., Phoenix, I., Lokugamage, N., Kalveram, B., Head, J. A., Tigabu, B., Smith, J. K., Zhang, L., Juelich, T. L., Gong, B., Freiberg, A. N. & Ikegami, T., Jul 1 2013, In : Journal of General Virology. 94, PART7, p. 1441-1450 10 p.

Research output: Contribution to journalArticle

12 Scopus citations
2020

VAMP8 contributes to the TRIM6-mediated type I interferon antiviral response during West Nile virus infection

Van Tol, S., Atkins, C., Bharaj, P., Johnson, K. N., Hage, A., Freiberg, A. N. & Rajsbaum, R., Jan 1 2020, In : Journal of virology. 94, 2, e01454-19.

Research output: Contribution to journalArticle

1 Scopus citations
2012

An assembly model of Rift Valley fever virus

Rusu, M., Bonneau, R., Holbrook, M. R., Watowich, S. J., Birmanns, S., Wriggers, W. & Freiberg, A. N., Jan 1 2012, In : Frontiers in Microbiology. 3, JUL

Research output: Contribution to journalArticle

25 Scopus citations
2013

Modeling pre-existing immunity to adenovirus in rodents: Immunological requirements for successful development of a recombinant adenovirus serotype 5-based ebola vaccine

Choi, J. H., Schafer, S. C., Zhang, L., Juelich, T., Freiberg, A. N. & Croyle, M. A., Sep 3 2013, In : Molecular Pharmaceutics. 10, 9, p. 3342-3355 14 p.

Research output: Contribution to journalArticle

12 Scopus citations
2016

ISG15 deficiency and increased viral resistance in humans but not mice

Speer, S. D., Li, Z., Buta, S., Payelle-Brogard, B., Qian, L., Vigant, F., Rubino, E., Gardner, T. J., Wedeking, T., Hermann, M., Duehr, J., Sanal, O., Tezcan, I., Mansouri, N., Tabarsi, P., Mansouri, D., Francois-Newton, V., Daussy, C. F., Rodriguez, M. R., Lenschow, D. J. & 7 others, Freiberg, A. N., Tortorella, D., Piehler, J., Lee, B., García-Sastre, A., Pellegrini, S. & Bogunovic, D., May 19 2016, In : Nature communications. 7, 11496.

Research output: Contribution to journalArticle

65 Scopus citations
2018

Experimental Infection of Syrian Hamsters with Aerosolized Nipah Virus

Escaffre, O., Hill, T., Ikegami, T., Juelich, T. L., Smith, J. K., Zhang, L., Perez, D. E., Atkins, C., Park, A., Lawrence, W., Sivasubramani, S. K., Peel, J. E., Peterson, J., Lee, B. & Freiberg, A., Oct 5 2018, In : Journal of Infectious Diseases. 218, 10, p. 1602-1610 9 p.

Research output: Contribution to journalArticle

4 Scopus citations
2013

The Dominant-negative inhibition of double-stranded RNA-Dependent protein kinase PKR increases the efficacy of rift valley fever virus MP-12 vaccine

Lihoradova, O., Kalveram, B., Indran, S. V., Lokugamage, N., Juelich, T. L., Hill, T. E., Tseng, C. T. K., Gong, B., Fukushi, S., Morikawa, S., Freiberg, A. N. & Ikegami, T., Oct 29 2013, In : Journal of virology. 87, 22, 1 p.

Research output: Contribution to journalComment/debate

2017

Recent advances in the development of antiviral therapeutics for Rift Valley fever virus infection

Atkins, C. & Freiberg, A., Nov 1 2017, In : Future Virology. 12, 11, p. 651-665 15 p.

Research output: Contribution to journalReview article

10 Scopus citations
2018

Favipiravir (T-705) protects against Nipah virus infection in the hamster model /631/326/22/1295 /631/326/596/1296 /13/106 /14/35 /38/77 /82/51 /96/63 article

Dawes, B. E., Kalveram, B., Ikegami, T., Juelich, T., Smith, J. K., Zhang, L., Park, A., Lee, B., Komeno, T., Furuta, Y. & Freiberg, A., Dec 1 2018, In : Scientific Reports. 8, 1, 7604.

Research output: Contribution to journalArticle

26 Scopus citations
2015

Rift Valley fever virus MP-12 vaccine is fully attenuated by a combination of partial attenuations in the S, M, and L segments

Ikegami, T., Hill, T. E., Smith, J. K., Zhang, L., Juelich, T. L., Gong, B., Slack, O. A. L., Ly, H. J., Lokugamage, N. & Freiberg, A., 2015, In : Journal of Virology. 89, 14, p. 7262-7276 15 p.

Research output: Contribution to journalArticle

25 Scopus citations
2013

The Lack of Maturation of Ebola Virus-Infected Dendritic Cells Results from the Cooperative Effect of at Least Two Viral Domains

Lubaki, N. M., Ilinykh, P., Pietzsch, C., Tigabu, B., Freiberg, A. N., Koup, R. A. & Bukreyev, A., Oct 29 2013, In : Journal of virology. 87, 22, 1 p.

Research output: Contribution to journalComment/debate

6 Scopus citations

A Mechanistic Paradigm for Broad-Spectrum Antivirals that Target Virus-Cell Fusion

Vigant, F., Lee, J., Hollmann, A., Tanner, L. B., Akyol Ataman, Z., Yun, T., Shui, G., Aguilar, H. C., Zhang, D., Meriwether, D., Roman-Sosa, G., Robinson, L. R., Juelich, T. L., Buczkowski, H., Chou, S., Castanho, M. A. R. B., Wolf, M. C., Smith, J. K., Banyard, A., Kielian, M. & 7 others, Reddy, S., Wenk, M. R., Selke, M., Santos, N. C., Freiberg, A. N., Jung, M. E. & Lee, B., Apr 2013, In : PLoS pathogens. 9, 4, e1003297.

Research output: Contribution to journalArticle

44 Scopus citations