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  • Chad Mire
2016

The synthetic antiviral drug arbidol inhibits globally prevalent pathogenic viruses

Pécheur, E. I., Borisevich, V., Halfmann, P., Morrey, J. D., Smee, D. F., Prichard, M., Mire, C. E., Kawaoka, Y., Geisbert, T. W. & Polyak, S. J., 2016, In : Journal of virology. 90, 6, p. 3086-3092 7 p.

Research output: Contribution to journalArticle

34 Scopus citations
2017

Transcriptome analysis of circulating immune cell subsets highlight the role of monocytes in Zaire Ebola Virus Makona pathogenesis

Menicucci, A. R., Versteeg, K., Woolsey, C., Mire, C., Geisbert, J. B., Cross, R., Agans, K. N., Jankeel, A., Geisbert, T. & Messaoudi, I., Oct 4 2017, In : Frontiers in Immunology. 8, OCT, 1372.

Research output: Contribution to journalArticle

15 Scopus citations

siRNA rescues nonhuman primates from advanced Marburg and Ravn virus disease

Thi, E. P., Mire, C., Lee, A. C. H., Geisbert, J. B., Ursic-Bedoya, R., Agans, K. N., Robbins, M., Deer, D. J., Cross, R., Kondratowicz, A. S., Fenton, K. A., MacLachlan, I. & Geisbert, T., Dec 1 2017, In : Journal of Clinical Investigation. 127, 12, p. 4437-4448 12 p.

Research output: Contribution to journalArticle

6 Scopus citations
2016

Isolation and characterization of a novel gammaherpesvirus from a microbat cell line

Shabman, R. S., Shrivastava, S., Tsibane, T., Attie, O., Jayaprakash, A., Mire, C. E., Dilley, K. E., Puri, V., Stockwell, T. B., Geisbert, T. W., Sachidanandam, R. & Basler, C. F., Jan 1 2016, In : mSphere. 1, 1, e00070-15.

Research output: Contribution to journalArticle

10 Scopus citations
2014

Deep sequencing identifies noncanonical editing of Ebola and Marburg virus RNAs in infected cells

Shabman, R. S., Jabado, O. J., Mire, C. E., Stockwell, T. B., Edwards, M., Mahajan, M., Geisbert, T. W. & Basler, C. F., 2014, In : mBio. 5, 6, p. e02011

Research output: Contribution to journalArticle

2019

A VP35 Mutant Ebola Virus Lacks Virulence but Can Elicit Protective Immunity to Wild-Type Virus Challenge

Woolsey, C., Menicucci, A. R., Cross, R., Luthra, P., Agans, K. N., Borisevich, V., Geisbert, J. B., Mire, C., Fenton, K. A., Jankeel, A., Anand, S., Ebihara, H., Geisbert, T., Messaoudi, I. & Basler, C. F., Sep 17 2019, In : Cell Reports. 28, 12, p. 3032-3046.e6

Research output: Contribution to journalArticle

Open Access
3 Scopus citations
2016

Targeting innate immunity for antiviral therapy through small molecule agonists of the RLR pathway

Pattabhi, S., Wilkins, C. R., Dong, R., Knoll, M. L., Posakony, J., Kaiser, S., Mire, C., Wang, M. L., Ireton, R. C., Geisbert, T., Bedard, K. M., Iadonato, S. P., Loo, Y. M. & Gale, M., 2016, In : Journal of Virology. 90, 5, p. 2372-2387 16 p.

Research output: Contribution to journalArticle

24 Scopus citations
2018

Post-exposure treatments for Ebola and Marburg virus infections

Cross, R. W., Mire, C. E., Feldmann, H. & Geisbert, T. W., Jun 1 2018, In : Nature Reviews Drug Discovery. 17, 6, p. 413-434 22 p.

Research output: Contribution to journalReview article

46 Scopus citations

Single-dose trivalent VesiculoVax vaccine protects macaques from lethal Ebolavirus and Marburgvirus challenge

Matassov, D., Mire, C. E., Latham, T., Geisbert, J. B., Xu, R., Ota-Setlik, A., Agans, K. N., Kobs, D. J., Wendling, M. Q. S., Burnaugh, A., Rudge, T. L., Sabourin, C. L., Egan, M. A., Clarke, D. K., Geisbert, T. W. & Eldridge, J. H., Feb 1 2018, In : Journal of virology. 92, 3, e01190-17.

Research output: Contribution to journalArticle

12 Scopus citations
2017

Therapeutic treatment of marburg and ravn virus infection in nonhuman primates with a human monoclonal antibody

Mire, C. E., Geisbert, J. B., Borisevich, V., Fenton, K. A., Agans, K. N., Flyak, A. I., Deer, D. J., Steinkellner, H., Bohorov, O., Bohorova, N., Goodman, C., Hiatt, A., Kim, D. H., Pauly, M. H., Velasco, J., Whaley, K. J., Crowe, J. E., Zeitlin, L. & Geisbert, T. W., Apr 5 2017, In : Science Translational Medicine. 9, 384, eaai8711.

Research output: Contribution to journalArticle

27 Scopus citations

Assessment of the potential for host-targeted iminosugars UV-4 and UV-5 activity against filovirus infections in vitro and in vivo

Warfield, K. L., Warren, T. K., Qiu, X., Wells, J., Mire, C., Geisbert, J. B., Stuthman, K. S., Garza, N. L., Van Tongeren, S. A., Shurtleff, A. C., Agans, K. N., Wong, G., Callahan, M. V., Geisbert, T., Klose, B., Ramstedt, U. & Treston, A. M., Feb 1 2017, In : Antiviral Research. 138, p. 22-31 10 p.

Research output: Contribution to journalArticle

9 Scopus citations
2015

Comparison of the Pathogenesis of the Angola and Ravn Strains of Marburg Virus in the Outbred Guinea Pig Model

Cross, R., Fenton, K. A., Geisbert, J. B., Ebihara, H., Mire, C. & Geisbert, T., Oct 1 2015, In : Journal of Infectious Diseases. 212, p. S258-S270

Research output: Contribution to journalArticle

24 Scopus citations
2014

The Marburg Virus VP24 Protein Interacts with Keap1 to Activate the Cytoprotective Antioxidant Response Pathway

Edwards, M. R., Johnson, B., Mire, C. E., Xu, W., Shabman, R. S., Speller, L. N., Leung, D. W., Geisbert, T. W., Amarasinghe, G. K. & Basler, C. F., Mar 27 2014, In : Cell Reports. 6, 6, p. 1017-1025 9 p.

Research output: Contribution to journalArticle

59 Scopus citations
2015

A Recombinant Vesicular Stomatitis Virus-Based Lassa Fever Vaccine Protects Guinea Pigs and Macaques against Challenge with Geographically and Genetically Distinct Lassa Viruses

Safronetz, D., Mire, C., Rosenke, K., Feldmann, F., Haddock, E., Geisbert, T. & Feldmann, H., Apr 17 2015, In : PLoS Neglected Tropical Diseases. 9, 4, e0003736.

Research output: Contribution to journalArticle

47 Scopus citations
2016

Single-vector, single-injection recombinant vesicular stomatitis virus vaccines against high-containment viruses

Whitt, M. A., Geisbert, T. W. & Mire, C. E., Apr 1 2016, Methods in Molecular Biology. Humana Press Inc., Vol. 1403. p. 295-311 17 p. (Methods in Molecular Biology; vol. 1403).

Research output: Chapter in Book/Report/Conference proceedingChapter

11 Scopus citations
2020

Quadrivalent VesiculoVax vaccine protects nonhuman primates from viral-induced hemorrhagic fever and death

Cross, R. W., Xu, R., Matassov, D., Hamm, S., Latham, T. E., Gerardi, C. S., Nowak, R. M., Geisbert, J. B., Ota-Setlik, A., Agans, K. N., Luckay, A., Witko, S. E., Soukieh, L., Deer, D. J., Mire, C. E., Feldmann, H., Happi, C., Fenton, K., Eldridge, J. H. & Geisbert, T. W., Jan 2 2020, In : Journal of Clinical Investigation. 130, 1, p. 539-551 13 p.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations
2019

Use of Single-Injection Recombinant Vesicular Stomatitis Virus Vaccine to Protect Nonhuman Primates Against Lethal Nipah Virus Disease

Mire, C., Geisbert, J. B., Agans, K. N., Versteeg, K. M., Deer, D. J., Satterfield, B. A., Fenton, K. A. & Geisbert, T., Jun 1 2019, In : Emerging infectious diseases. 25, 6, p. 1144-1152 9 p.

Research output: Contribution to journalArticle

Open Access
3 Scopus citations
2018

A prophylactic multivalent vaccine against different filovirus species is immunogenic and provides protection from lethal infections with Ebolavirus and Marburgvirus species in non-human primates

Callendret, B., Vellinga, J., Wunderlich, K., Rodriguez, A., Steigerwald, R., Dirmeier, U., Cheminay, C., Volkmann, A., Brasel, T., Carrion, R., Giavedoni, L. D., Patterson, J. L., Mire, C. E., Geisbert, T. W., Hooper, J. W., Weijtens, M., Hartkoorn-Pasma, J., Custers, J., Pau, M. G., Schuitemaker, H. & 1 others, Zahn, R., Feb 2018, In : PloS one. 13, 2, e0192312.

Research output: Contribution to journalArticle

16 Scopus citations
2017

Disposable cartridge platform for rapid detection of viral hemorrhagic fever viruses

Scherr, S. M., Freedman, D. S., Agans, K. N., Rosca, A., Carter, E., Kuroda, M., Fawcett, H. E., Mire, C. E., Geisbert, T. W., Ünlü, M. S. & Connor, J. H., Mar 7 2017, In : Lab on a Chip. 17, 5, p. 917-925 9 p.

Research output: Contribution to journalArticle

9 Scopus citations
2016

Treatment of Lassa virus infection in outbred guinea pigs with first-in-class human monoclonal antibodies

Cross, R., Mire, C., Branco, L. M., Geisbert, J. B., Rowland, M. M., Heinrich, M. L., Goba, A., Momoh, M., Grant, D. S., Fullah, M., Khan, S. H., Robinson, J. E., Geisbert, T. & Garry, R. F., Sep 1 2016, In : Antiviral Research. 133, p. 218-222 5 p.

Research output: Contribution to journalArticle

26 Scopus citations
2015

Modeling the Disease Course of Zaire ebolavirus Infection in the Outbred Guinea Pig

Cross, R., Fenton, K. A., Geisbert, J. B., Mire, C. & Geisbert, T., Oct 1 2015, In : Journal of Infectious Diseases. 212, p. S305-S315

Research output: Contribution to journalArticle

29 Scopus citations
2014

Deep sequencing identifies noncanonical editing of Ebola and Marburg virus RNAS in infected cells

Shabman, R. S., Jabado, O. J., Mire, C. E., Stockwell, T. B., Edwards, M., Mahajan, M., Geisbert, T. W. & Basler, C. F., Sep 25 2014, In : mBio. 5, 6, e02011-14.

Research output: Contribution to journalArticle

43 Scopus citations
2015

Lipid nanoparticle siRNA treatment of Ebola-virus-Makona-infected nonhuman primates

Thi, E. P., Mire, C., Lee, A. C. H., Geisbert, J. B., Zhou, J. Z., Agans, K. N., Snead, N. M., Deer, D. J., Barnard, T. R., Fenton, K. A., Maclachlan, I. & Geisbert, T., May 21 2015, In : Nature. 521, 7552, p. 362-365 4 p.

Research output: Contribution to journalArticle

151 Scopus citations

The immunomodulating v and W proteins of Nipah virus determine disease course

Satterfield, B. A., Cross, R., Fenton, K. A., Agans, K. N., Basler, C. F., Geisbert, T. & Mire, C., Jun 24 2015, In : Nature Communications. 6, 7483.

Research output: Contribution to journalArticle

27 Scopus citations
2017

Enhanced light microscopy visualization of virus particles from Zika virus to filamentous ebolaviruses

Daaboul, G. G., Freedman, D. S., Scherr, S. M., Carter, E., Rosca, A., Bernstein, D., Mire, C. E., Agans, K. N., Hoenen, T., Geisbert, T. W., Selim Ünlü, M. & Connor, J. H., Jun 2017, In : PloS one. 12, 6, e0179728.

Research output: Contribution to journalArticle

5 Scopus citations
2019

Antagonism of STAT1 by Nipah virus P gene products modulates disease course but not lethal outcome in the ferret model

Satterfield, B. A., Borisevich, V., Foster, S. L., Rodriguez, S. E., Cross, R. W., Fenton, K., Agans, K. N., Basler, C. F., Geisbert, T. W. & Mire, C. E., Dec 1 2019, In : Scientific reports. 9, 1, 16710.

Research output: Contribution to journalArticle

Open Access
2015

Erratum: Analytical performance characteristics of the cepheid genexpert ebola assay for the detection of ebola virus (PLoS One)

Pinsky, B. A., Sahoo, M. K., Sandlund, J., Kleman, M., Kulkarni, M., Grufman, P., Nygren, M., Kwiatkowski, R., Baron, E. J., Tenover, F., Denison, B., Higuchi, R., Van Atta, R., Beer, N. R., Carrillo, A. C., Naraghi-Arani, P., Mire, C. E., Ranadheera, C., Grolla, A., Lagerqvist, N. & 1 others, Persing, D. H., Dec 1 2015, In : PloS one. 10, 12, 0145896.

Research output: Contribution to journalComment/debate

3 Scopus citations
2018

Efficacy of Human Monoclonal Antibody Monotherapy Against Bundibugyo Virus Infection in Nonhuman Primates

Gilchuk, P., Mire, C., Geisbert, J. B., Agans, K. N., Deer, D. J., Cross, R., Slaughter, J. C., Flyak, A. I., Mani, J., Pauly, M. H., Velasco, J., Whaley, K. J., Zeitlin, L., Geisbert, T. & Crowe, J. E., Nov 22 2018, In : The Journal of infectious diseases. 218, 5, p. S565-S573

Research output: Contribution to journalArticle

1 Scopus citations