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  • Slobodan Paessler
2020

The Glycoprotein of the Live-Attenuated Junin Virus Vaccine Strain Induces Endoplasmic Reticulum Stress and Forms Aggregates prior to Degradation in the Lysosome

Manning, J. T., Yun, N. E., Seregin, A. V., Koma, T., Sattler, R. A., Ezeomah, C., Huang, C., de la Torre, J. C. & Paessler, S., Mar 31 2020, In : Journal of virology. 94, 8

Research output: Contribution to journalArticle

2017

Mouse model of neurological complications resulting from encephalitic alphavirus infection

Ronca, S. E., Smith, J., Koma, T., Miller, M. M., Yun, N., Dineley, K. & Paessler, S., Feb 7 2017, In : Frontiers in Microbiology. 8, FEB, 188.

Research output: Contribution to journalArticle

1 Scopus citations
2013

CDK9-dependent transcriptional elongation in the innate interferon-stimulated gene response to respiratory syncytial virus infection in airway epithelial cells

Tian, B., Zhao, Y., Kalita, M., Edeh, C. B., Paessler, S., Casola, A., Teng, M. N., Garofalo, R. P. & Brasier, A. R., Jun 1 2013, In : Journal of virology. 87, 12, p. 7075-7092 18 p.

Research output: Contribution to journalArticle

40 Scopus citations
2015

In silico analysis suggests repurposing of ibuprofen for prevention and treatment of EBOLA virus disease

Veljkovic, V., Goeijenbier, M., Glisic, S., Veljkovic, N., Perovic, V. R., Sencanski, M., Branch, D. R. & Paessler, S., May 1 2015, In : F1000Research. 4, 104.

Research output: Contribution to journalArticle

10 Scopus citations
2017

Lassa virus reverse genetics

Martínez-Sobrido, L., Paessler, S. & de la Torre, J. C., 2017, Methods in Molecular Biology. Humana Press Inc., Vol. 1602. p. 185-204 20 p. (Methods in Molecular Biology; vol. 1602).

Research output: Chapter in Book/Report/Conference proceedingChapter

5 Scopus citations
2018

Cocaine evokes a profile of oxidative stress and impacts innate antiviral response pathways in astrocytes

Cisneros, I., Erdenizmenli, M., Cunningham, K., Paessler, S. & Dineley, K., Jun 1 2018, In : Neuropharmacology. 135, p. 431-443 13 p.

Research output: Contribution to journalArticle

6 Scopus citations
2016

Machupo virus expressing GPC of the Candid#1 vaccine strain of Junin virus is highly attenuated and immunogenic

Koma, T., Patterson, M., Huang, C., Seregin, A. V., Maharaj, P. D., Miller, M., Smith, J. N., Walker, A. G., Hallam, S. & Paessler, S., 2016, In : Journal of Virology. 90, 3, p. 1290-1297 8 p.

Research output: Contribution to journalArticle

7 Scopus citations

Neuropsychological, Neurovirological and Neuroimmune Aspects of Abnormal GABAergic Transmission in HIV Infection

Buzhdygan, T., Lisinicchia, J., Patel, V., Johnson, K., Neugebauer, V., Paessler, S., Jennings, K. & Gelman, B., Jun 1 2016, In : Journal of Neuroimmune Pharmacology. 11, 2, p. 279-293 15 p.

Research output: Contribution to journalArticle

16 Scopus citations
2011

Rescue from cloned cDNAs and in vivo characterization of recombinant pathogenic romero and live-attenuated candid #1 strains of Junin virus, the causative agent of argentine hemorrhagic fever disease

Emonet, S. F., Seregin, A. V., Yun, N. E., Poussard, A. L., Walker, A. G., De La Torre, J. C. & Paessler, S., Feb 1 2011, In : Journal of virology. 85, 4, p. 1473-1483 11 p.

Research output: Contribution to journalArticle

61 Scopus citations
2018

Lassa fever–induced sensorineural hearing loss: A neglected public health and social burden

Mateer, E. J., Huang, C., Shehu, N. Y. & Paessler, S., Feb 22 2018, In : PLoS neglected tropical diseases. 12, 2, e0006187.

Research output: Contribution to journalReview article

29 Scopus citations
2017

A simple method for calculation of basic molecular properties of nutrients and their use as a criterion for a healthy diet

Veljkovic, V., Perovic, V., Anderluh, M., Paessler, S., Veljkovic, M., Glisic, S. & Nicolson, G., Jan 1 2017, In : F1000Research. 6, 13.

Research output: Contribution to journalArticle

2 Scopus citations

Highly pathogenic New World arenavirus infection activates the pattern recognition receptor protein kinase R without attenuating virus replication in human cells

Huang, C., Kolokoltsova, O. A., Mateer, E. J., Koma, T. & Paessler, S., Oct 1 2017, In : Journal of Virology. 91, 20, e01090-17.

Research output: Contribution to journalArticle

8 Scopus citations
2013

Pathogenesis of Venezuelan equine encephalitis

Taylor, K. G. & Paessler, S., Nov 29 2013, In : Veterinary Microbiology. 167, 1-2, p. 145-150 6 p.

Research output: Contribution to journalArticle

22 Scopus citations
2012

Junín virus infection activates the type I interferon pathway in a RIG-I-dependent manner

Huang, C., Kolokoltsova, O. A., Yun, N. E., Seregin, A. V., Poussard, A. L., Walker, A. G., Brasier, A. R., Zhao, Y., Tian, B., de la Torre, J. C. & Paessler, S., May 2012, In : PLoS neglected tropical diseases. 6, 5, e1659.

Research output: Contribution to journalArticle

41 Scopus citations
2013

Alphavirus neurovirulence

Taylor, K. & Paessler, S., Jan 1 2013, Neuroviral Infections: RNA Viruses and Retroviruses. CRC Press, p. 3-20 18 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

2018
4 Scopus citations
2016

Neurological sequelae resulting from encephalitic alphavirus infection

Ronca, S. E., Dineley, K. & Paessler, S., 2016, In : Frontiers in Microbiology. 7, JUN, 959.

Research output: Contribution to journalReview article

22 Scopus citations
2018

Ibuprofen as a template molecule for drug design against Ebola virus

Paessler, S., Huang, C., Sencanski, M., Veljkovic, N., Perovic, V., Glisic, S. & Veljkovic, V., Jan 1 2018, In : Frontiers in Bioscience - Landmark. 23, 5, p. 947-953 7 p.

Research output: Contribution to journalArticle

9 Scopus citations
2012

Resequencing of the puumala virus strain sotkamo from the WHO arbovirus collection

Kurolt, I. C., Paessler, S. & Markotić, A., Oct 1 2012, In : Virus Genes. 45, 2, p. 389-392 4 p.

Research output: Contribution to journalArticle

2011

Prevention of influenza virus shedding and protection from lethal H1N1 challenge using a consensus 2009 H1N1 HA and NA adenovirus vector vaccine

Jones, F. R., Gabitzsch, E. S., Xu, Y., Balint, J. P., Borisevich, V., Smith, J., Smith, J., Peng, B. H., Walker, A., Salazar, M. & Paessler, S., Sep 16 2011, In : Vaccine. 29, 40, p. 7020-7026 7 p.

Research output: Contribution to journalArticle

17 Scopus citations

Rapid, non-invasive imaging of alphaviral brain infection: Reducing animal numbers and morbidity to identify efficacy of potential vaccines and antivirals

Patterson, M., Poussard, A., Taylor, K., Seregin, A., Smith, J., Peng, B. H., Walker, A., Linde, J., Smith, J., Salazar, M. & Paessler, S., Nov 21 2011, In : Vaccine. 29, 50, p. 9345-9351 7 p.

Research output: Contribution to journalArticle

14 Scopus citations
2020

Antiviral activities of type I interferons to SARS-CoV-2 infection

Mantlo, E., Bukreyeva, N., Maruyama, J., Paessler, S. & Huang, C., Jul 2020, In : Antiviral research. 179, 104811.

Research output: Contribution to journalArticle

Open Access
15 Scopus citations
2014

RIG-I enhanced interferon independent apoptosis upon Junin virus infection

Kolokoltsova, O. A., Grant, A. M., Huang, C., Smith, J. K., Poussard, A. L., Tian, B., Brasier, A. R., Peters, C. J., Tseng, C. T. K., De La Torre, J. C. & Paessler, S., Jun 11 2014, In : PloS one. 9, 6, e99610.

Research output: Contribution to journalArticle

14 Scopus citations
2016

The Ectodomain of Glycoprotein from the Candid#1 Vaccine Strain of Junin Virus Rendered Machupo Virus Partially Attenuated in Mice Lacking IFN-αβ/γ Receptor

Koma, T., Huang, C., Aronson, J. F., Walker, A. G., Miller, M., Smith, J. N., Patterson, M. & Paessler, S., Aug 30 2016, In : PLoS neglected tropical diseases. 10, 8, e0004969.

Research output: Contribution to journalArticle

4 Scopus citations
2015

The glycoprotein precursor gene of Junin virus determines the virulence of the romero strain and the attenuation of the Candid #1 strain in a representative animal model of Argentine hemorrhagic fever

Seregin, A. V., Yun, N. E., Miller, M., Aronson, J., Smith, J. K., Walker, A. G., Smith, J. N., Huang, C., Manning, J., de la Torre, J. C. & Paessler, S., 2015, In : Journal of Virology. 89, 11, p. 5949-5956 8 p.

Research output: Contribution to journalArticle

21 Scopus citations
2012

In vivo imaging systems (IVIS) detection of a neuro-invasive encephalitic virus.

Poussard, A., Patterson, M., Taylor, K., Seregin, A., Smith, J., Smith, J., Salazar, M. & Paessler, S., 2012, In : Journal of visualized experiments : JoVE. 70, p. e4429

Research output: Contribution to journalArticle

9 Scopus citations

Natural killer cell mediated pathogenesis determines outcome of central nervous system infection with Venezuelan equine encephalitis virus in C3H/HeN mice

Taylor, K., Kolokoltsova, O., Patterson, M., Poussard, A., Smith, J., Estes, D. M. & Paessler, S., Jun 8 2012, In : Vaccine. 30, 27, p. 4095-4105 11 p.

Research output: Contribution to journalArticle

13 Scopus citations
2018

Zika virus infection elicits auto-antibodies to C1q

Koma, T., Veljkovic, V., Anderson, D. E., Wang, L. F., Rossi, S. L., Shan, C., Shi, P. Y., Beasley, D. W., Bukreyeva, N., Smith, J. N., Hallam, S., Huang, C., Von Messling, V. & Paessler, S., Dec 1 2018, In : Scientific reports. 8, 1, 1882.

Research output: Contribution to journalArticle

9 Scopus citations
2012

Viral Hemorrhagic Fevers: South American Hemorrhagic Fevers

Paessler, S., Nov 1 2012, Hunter's Tropical Medicine and Emerging Infectious Disease: Ninth Edition. Elsevier Inc., p. 328-330 3 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

2015

PARP9-DTX3L ubiquitin ligase targets host histone H2BJ and viral 3C protease to enhance interferon signaling and control viral infection

Zhang, Y., Mao, D., Roswit, W. T., Jin, X., Patel, A. C., Patel, D. A., Agapov, E., Wang, Z., Tidwell, R. M., Atkinson, J. J., Huang, G., McCarthy, R., Yu, J., Yun, N. E., Paessler, S., Lawson, T. G., Omattage, N. S., Brett, T. J. & Holtzman, M. J., Dec 1 2015, In : Nature Immunology. 16, 12, p. 1215-1227 13 p.

Research output: Contribution to journalArticle

46 Scopus citations
2016

Characterization of a novel murine model to study zika virus

Rossi, S. L., Tesh, R. B., Azar, S. R., Muruato, A. E., Hanley, K. A., Auguste, A. J., Langsjoen, R. M., Paessler, S., Vasilakis, N. & Weaver, S. C., Jun 1 2016, In : American Journal of Tropical Medicine and Hygiene. 94, 6, p. 1362-1369 8 p.

Research output: Contribution to journalArticle

291 Scopus citations
2012

Junín virus pathogenesis and virus replication

Grant, A., Seregin, A., Huang, C., Kolokoltsova, O., Brasier, A., Peters, C. & Paessler, S., Oct 2012, In : Viruses. 4, 10, p. 2317-2339 23 p.

Research output: Contribution to journalReview article

39 Scopus citations
2013

Mice lacking functional STAT1 are highly susceptible to lethal infection with Lassa virus

Yun, N. E., Seregin, A. V., Walker, D. H., Popov, V. L., Walker, A. G., Smith, J. N., Miller, M., de la Torre, J. C., Smith, J. K., Borisevich, V., Fair, J. N., Wauquier, N., Grant, D. S., Bockarie, B., Bente, D. & Paessler, S., Oct 28 2013, In : Journal of virology. 87, 19, p. 10908-10911 4 p.

Research output: Contribution to journalArticle

30 Scopus citations
2017

MAVS is essential for primary CD4+ T cell immunity but not for recall T cell responses following an attenuated West Nile virus infection

Luo, H., Winkelmann, E., Xie, G., Fang, R., Peng, B. H., Li, L., Lazear, H. M., Paessler, S., Diamond, M. S., Gale, M., Barrett, A. D. & Wang, T., 2017, In : Journal of virology. 91, 6, e02097-16.

Research output: Contribution to journalArticle

5 Scopus citations
2020

Fentanyl self-administration impacts brain immune responses in male Sprague-Dawley rats

Ezeomah, C., Cunningham, K. A., Stutz, S. J., Fox, R. G., Bukreyeva, N., Dineley, K. T., Paessler, S. & Cisneros, I. E., Jul 2020, In : Brain, Behavior, and Immunity. 87, p. 725-738 14 p.

Research output: Contribution to journalArticle

1 Scopus citations
2018

Using electronic biology based platform to predict flu vaccine efficacy for 2018/2019

Veljkovic, V. & Paessler, S., Jan 1 2018, In : F1000Research. 7, 298.

Research output: Contribution to journalArticle

3 Scopus citations
2014

A viral RNA structural element alters host recognition of nonself RNA

Hyde, J. L., Gardner, C. L., Kimura, T., White, J. P., Liu, G., Trobaugh, D. W., Huang, C., Tonelli, M., Paessler, S., Takeda, K., Klimstra, W. B., Amarasinghe, G. K. & Diamond, M. S., Jan 1 2014, In : Science. 343, 6172, p. 783-787 5 p.

Research output: Contribution to journalArticle

80 Scopus citations
2011

Antiviral activity of a small-molecule inhibitor of arenavirus glycoprotein processing by the cellular site 1 protease

Urata, S., Yun, N., Pasquato, A., Paessler, S., Kunz, S. & De La Torre, J. C., Jan 1 2011, In : Journal of virology. 85, 2, p. 795-803 9 p.

Research output: Contribution to journalArticle

48 Scopus citations
2015

Highly pathogenic New World and Old World human arenaviruses induce distinct interferon responses in human cells

Huang, C., Kolokoltsova, O. A., Yun, N. E., Seregin, A. V., Ronca, S., Koma, T. & Paessler, S., 2015, In : Journal of virology. 89, 14, p. 7079-7088 10 p.

Research output: Contribution to journalArticle

19 Scopus citations
2018

Vaccine-elicited receptor-binding site antibodies neutralize two New World hemorrhagic fever arenaviruses

Clark, L. E., Mahmutovic, S., Raymond, D. D., Dilanyan, T., Koma, T., Manning, J. T., Shankar, S., Levis, S. C., Briggiler, A. M., Enria, D. A., Wucherpfennig, K. W., Paessler, S. & Abraham, J., Dec 1 2018, In : Nature communications. 9, 1, 1884.

Research output: Contribution to journalArticle

8 Scopus citations
2014
64 Scopus citations
2013

Innate immune response to arenaviral infection: A focus on the highly pathogenic new world hemorrhagic arenaviruses

Koma, T., Huang, C., Kolokoltsova, O. A., Brasier, A. R. & Paessler, S., Dec 13 2013, In : Journal of Molecular Biology. 425, 24, p. 4893-4903 11 p.

Research output: Contribution to journalReview article

18 Scopus citations
2015

Lassa virus isolates from Mali and the Ivory Coast represent an emerging fifth lineage

Manning, J. T., Forrester, N. & Paessler, S., 2015, In : Frontiers in Microbiology. 6, OCT, 1037.

Research output: Contribution to journalArticle

32 Scopus citations
2017

Ebola Virus and Marburg Virus in Human Milk Are Inactivated by Holder Pasteurization

Hamilton Spence, E., Huff, M., Shattuck, K., Vickers, A., Yun, N. & Paessler, S., May 1 2017, In : Journal of Human Lactation. 33, 2, p. 351-354 4 p.

Research output: Contribution to journalArticle

9 Scopus citations
2012

Functional interferon system is required for clearance of Lassa virus

Yun, N. E., Poussard, A. L., Seregin, A. V., Walker, A. G., Smith, J. K., Aronson, J. F., Smith, J. N., Soong, L. & Paessler, S., Mar 2012, In : Journal of virology. 86, 6, p. 3389-3392 4 p.

Research output: Contribution to journalArticle

32 Scopus citations
2016

Predicted enhanced human propensity of current avian-like H1N1 swine influenza virus from China

Veljkovic, V., Veljkovic, N., Paessler, S., Goeijenbier, M., Perovic, V., Glisic, S. & Muller, C. P., Nov 1 2016, In : PloS one. 11, 11, e0165451.

Research output: Contribution to journalArticle

1 Scopus citations
2012

Control of SIV infection and subsequent induction of pandemic H1N1 immunity in rhesus macaques using an Ad5 [E1-, E2b-] vector platform

Gabitzsch, E. S., Balint-Junior, J. P., Xu, Y., Balcaitis, S., Sanders-Beer, B., Karl, J., Weinhold, K. J., Paessler, S. & Jones, F. R., Nov 26 2012, In : Vaccine. 30, 50, p. 7265-7270 6 p.

Research output: Contribution to journalArticle

8 Scopus citations
2017

Prediction of influenza vaccine effectiveness for the influenza season 2017/18 in the US

Veljkovic, V. & Paessler, S., Jan 1 2017, In : F1000Research. 6, 2067.

Research output: Contribution to journalArticle

5 Scopus citations
2016

Animal model of sensorineural hearing loss associated with Lassa virus infection

Yun, N. E., Ronca, S., Tamura, A., Koma, T., Seregin, A. V., Dineley, K. T., Miller, M., Cook, R., Shimizu, N., Walker, A. G., Smith, J. N., Fair, J. N., Wauquier, N., Bockarie, B., Khan, S. H., Makishima, T. & Paessler, S., Jan 1 2016, In : Journal of virology. 90, 6, p. 2920-2927 8 p.

Research output: Contribution to journalArticle

27 Scopus citations
2015

Evolution of 2014/15 H3N2 influenza viruses circulating in US: Consequences for vaccine effectiveness and possible new pandemic

Veljkovic, V., Paessler, S., Glisic, S., Prljic, J., Perovic, V. R., Veljkovic, N. & Scotch, M., 2015, In : Frontiers in Microbiology. 6, DEC, 01456.

Research output: Contribution to journalArticle

8 Scopus citations