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Author

  • Richard Pyles
2014

Cultivated vaginal microbiomes alter HIV-1 infection and antiretroviral efficacy in colonized epithelial multilayer cultures

Pyles, R. B., Vincent, K. L., Baum, M. M., Elsom, B., Miller, A. L., Maxwell, C., Eaves-Pyles, T. D., Li, G., Popov, V. L., Nusbaum, R. J. & Ferguson, M. R., Mar 27 2014, In : PloS one. 9, 3, e93419.

Research output: Contribution to journalArticle

27 Scopus citations
2017

A lethal model of disseminated dengue virus type 1 infection in AG129 mice

Milligan, G., Sarathy, V., White, M. M., Greenberg, M. B., Campbell, G., Pyles, R., Barrett, A. & Bourne, N., Oct 1 2017, In : Journal of General Virology. 98, 10, p. 2507-2519 13 p., 000923.

Research output: Contribution to journalArticle

7 Scopus citations
2018
3 Scopus citations
2020

Growth Hormone Alters Brain Morphometry, Connectivity, and Behavior in Subjects with Fatigue after Mild Traumatic Brain Injury

Wright, T., Urban, R., Durham, W., Dillon, E. L., Randolph, K. M., Danesi, C., Gilkison, C., Karmonik, C., Zgaljardic, D., Masel, B., Bishop, J., Pyles, R., Seidler, R., Hierholzer, A. H. & Moore, M., Apr 15 2020, In : Journal of neurotrauma. 37, 8, p. 1052-1066 15 p.

Research output: Contribution to journalArticle

3 Scopus citations
2018

Production and transplantation of bioengineered lung into a large-animal model

Nichols, J. E., La Francesca, S., Niles, J. A., Vega, S. P., Argueta, L. B., Frank, L., Christiani, D. C., Pyles, R. B., Himes, B. E., Zhang, R., Li, S., Sakamoto, J., Rhudy, J., Hendricks, G., Begarani, F., Liu, X., Patrikeev, I., Pal, R., Usheva, E., Vargas, G. & 7 others, Miller, A., Woodson, L. C., Wacher, A., Grimaldo, M., Weaver, D., Mlcak, R. & Cortiella, J., Aug 1 2018, In : Science Translational Medicine. 10, 452, eaao3926.

Research output: Contribution to journalArticle

29 Scopus citations
2015

Evaluation of simultaneous transmission of chikungunya virus and dengue virus type 2 in infected Aedes aegypti and Aedes albopictus (diptera: Culicidae)

Nuckols, J. T., Huang, Y. J. S., Higgs, S., Miller, A. L., Pyles, R., Spratt, H., Horne, K. M. & Vanlandingham, D. L., May 1 2015, In : Journal of Medical Entomology. 52, 3, p. 447-451 5 p.

Research output: Contribution to journalArticle

24 Scopus citations
2014
7 Scopus citations
2015
39 Scopus citations
2014

A structurally distinct human mycoplasma protein that generically blocks antigen-antibody union

Grover, R. K., Zhu, X., Nieusma, T., Jones, T., Boero, I., MacLeod, A. S., Mark, A., Niessen, S., Kim, H. J., Kong, L., Assad-Garcia, N., Kwon, K., Chesi, M., Smider, V. V., Salomon, D. R., Jelinek, D. F., Kyle, R. A., Pyles, R. B., Glass, J. I., Ward, A. B. & 2 others, Wilson, I. A. & Lerner, R. A., 2014, In : Science. 343, 6171, p. 656-661 6 p.

Research output: Contribution to journalArticle

35 Scopus citations
2018

Transcriptional Analysis of the Guinea Pig Mucosal Immune Response to Intravaginal Infection with Herpes Simplex Virus Type 2

Veselenak, R. L., Milligan, G., Miller, A. L., Pyles, R. & Bourne, N., May 1 2018, In : Virology. 518, p. 349-357 9 p.

Research output: Contribution to journalArticle

2 Scopus citations
2013

Photochemical inactivation of chikungunya virus in plasma and platelets using the Mirasol pathogen reduction technology system

Vanlandingham, D. L., Keil, S. D., Horne, K. M. E., Pyles, R., Goodrich, R. P. & Higgs, S., Feb 1 2013, In : Transfusion. 53, 2, p. 284-290 7 p.

Research output: Contribution to journalArticle

33 Scopus citations
2012

A Vaxfectin®-adjuvanted HSV-2 plasmid DNA vaccine is effective for prophylactic and therapeutic use in the guinea pig model of genital herpes

Veselenak, R. L., Shlapobersky, M., Pyles, R. B., Wei, Q., Sullivan, S. M. & Bourne, N., Nov 19 2012, In : Vaccine. 30, 49, p. 7046-7051 6 p.

Research output: Contribution to journalArticle

38 Scopus citations
2011

Comparison of the filmarray respiratory panel and prodesse real-time PCR assays for detection of respiratory pathogens

Loeffelholz, M. J., Pong, D. L., Pyles, R. B., Xiong, Y., Miller, A. L., Bufton, K. K. & Chonmaitree, T., Dec 1 2011, In : Journal of Clinical Microbiology. 49, 12, p. 4083-4088 6 p.

Research output: Contribution to journalArticle

87 Scopus citations
2012

Viral load and acute otitis media development after human metapneumovirus upper respiratory tract infection

Nokso-Koivisto, J., Pyles, R. B., Miller, A. L., Patel, J. A., Loeffelholz, M. & Chonmaitree, T., Jul 1 2012, In : Pediatric Infectious Disease Journal. 31, 7, p. 763-766 4 p.

Research output: Contribution to journalArticle

12 Scopus citations

Commensal bacteria modulate innate immune responses of vaginal epithelial cell multilayer cultures

Rose, W. A., McGowin, C. L., Spagnuolo, R. A., Eaves-Pyles, T. D., Popov, V. L. & Pyles, R. B., Mar 7 2012, In : PloS one. 7, 3, e32728.

Research output: Contribution to journalArticle

63 Scopus citations
2014

Evolution of a cell culture-derived genotype 1a hepatitis C Virus (H77S.2) during persistent infection with chronic hepatitis in a Chimpanzee

Yi, M. K., Hu, F., Joyce, M., Saxena, V., Welsch, C., Chavez, D., Guerra, B., Yamane, D., Veselenak, R., Pyles, R., Walker, C. M., Tyrrell, L., Bourne, N., Lanford, R. E. & Lemon, S. M., Apr 2014, In : Journal of virology. 88, 7, p. 3678-3694 17 p.

Research output: Contribution to journalArticle

Open Access
20 Scopus citations
2016

New Systems for Studying Intercellular Interactions in Bacterial Vaginosis

Herbst-Kralovetz, M. M., Pyles, R., Ratner, A. J., Sycuro, L. K. & Mitchell, C., Aug 15 2016, In : Journal of Infectious Diseases. 214, p. S6-S13

Research output: Contribution to journalArticle

17 Scopus citations
2018

Safety and pharmacokinetics of single, dual, and triple antiretroviral drug formulations delivered by pod-intravaginal rings designed for HIV-1 prevention: A Phase I trial

Vincent, K. L., Moss, J. A., Marzinke, M. A., Hendrix, C. W., Anton, P. A., Pyles, R. B., Guthrie, K. M., Dawson, L., Olive, T. J., Butkyavichene, I., Churchman, S. A., Cortez, J. M., Fanter, R., Gunawardana, M., Miller, C. S., Yang, F., Rosen, R. K., Vargas, S. E. & Baum, M. M., Sep 2018, In : PLoS Medicine. 15, 9, e1002655.

Research output: Contribution to journalArticle

10 Scopus citations
2017

Vaginal ecosystem modeling of growth patterns of anaerobic bacteria in microaerophilic conditions

Medina-Colorado, A. A., Vincent, K. L., Miller, A. L., Maxwell, C. A., Dawson, L. N., Olive, T., Kozlova, E. V., Baum, M. M. & Pyles, R. B., Jun 2017, In : Anaerobe. 45, p. 10-18 9 p.

Research output: Contribution to journalArticle

3 Scopus citations
2014

Investigating the efficacy of monovalent and tetravalent dengue vaccine formulations against DENV-4 challenge in AG129 mice

Fuchs, J., Chu, H., O'Day, P., Pyles, R., Bourne, N., Das, S. C., Milligan, G. N., Barrett, A. D. T., Partidos, C. D. & Osorio, J. E., Nov 12 2014, In : Vaccine. 32, 48, p. 6537-6543 7 p.

Research output: Contribution to journalArticle

21 Scopus citations
2018

Phase I trial of pod-intravaginal rings delivering antiretroviral agents for HIV-1 prevention: Rectal drug exposure from vaginal dosing with tenofovir disoproxil fumarate, emtricitabine, and maraviroc

Vincent, K. L., Moss, J. A., Marzinke, M. A., Hendrix, C. W., Anton, P. A., Gunawardana, M., Dawson, L. N., Olive, T. J., Pyles, R. B. & Baum, M. M., Aug 2018, In : PloS one. 13, 8, e0201952.

Research output: Contribution to journalArticle

6 Scopus citations
2014

Enter protein m

Grover, R. K., Zhu, X., Nieusma, T., Jones, T., Boero, I., MacLeod, A. S., Mark, A., Niessen, S., Kim, H. J., Kong, L., Assad-Garcia, N., Kwon, K., Chesi, M., Smider, V. V., Salomon, D. R., Jelinek, D. F., Kyle, R. A., Pyles, R. B., Glass, J. I., Ward, A. B. & 2 others, Wilson, I. A. & Lerner, R. A., May 1 2014, In : Assay and Drug Development Technologies. 12, 4, p. 204-206 3 p.

Research output: Contribution to journalComment/debate

Duration of rhinovirus shedding in the upper respiratory tract in the first year of life

Loeffelholz, M. J., Trujillo, R., Pyles, R. B., Miller, A. L., Alvarez-Fernandez, P., Pong, D. L. & Chonmaitree, T., Dec 1 2014, In : Pediatrics. 134, 6, p. 1144-1150 7 p.

Research output: Contribution to journalArticle

43 Scopus citations
2013

Immunomodulatory and antibacterial effects of cystatin 9 against Francisella tularensis

Eaves-Pyles, T., Patel, J., Arigi, E., Cong, Y., Cao, A., Garg, N., Dhiman, M., Pyles, R. B., Arulanandam, B., Miller, A. L., Popov, V. L., Soong, L., Carlsen, E. D., Coletta, C., Szabo, C. & Almeida, I. C., Sep 4 2013, In : Molecular Medicine. 19, 1, p. 263-275 13 p.

Research output: Contribution to journalArticle

7 Scopus citations
2014

Use of a guinea pig-specific transcriptome array for evaluation of protective immunity against genital chlamydial infection following intranasal vaccination in guinea pigs

Wali, S., Gupta, R., Veselenak, R. L., Li, Y., Yu, J. J., Murthy, A. K., Cap, A. P., Neal Guentzel, M., Chambers, J. P., Zhong, G., Rank, R. G., Pyles, R. B. & Arulanandam, B. P., Dec 11 2014, In : PloS one. 9, 12, e114261.

Research output: Contribution to journalArticle

8 Scopus citations
2016

Determining Persistence of Bocavirus DNA in the Respiratory Tract of Children by Pyrosequencing

Wagner, J. C., Pyles, R. B., Miller, A. L., Nokso-Koivisto, J., Loeffelholz, M. J. & Chonmaitree, T., May 1 2016, In : Pediatric Infectious Disease Journal. 35, 5, p. 471-476 6 p.

Research output: Contribution to journalArticle

14 Scopus citations
2011

Viral-bacterial interactions and risk of acute otitis media complicating upper respiratory tract infection

Pettigrew, M. M., Gent, J. F., Pyles, R. B., Miller, A. L., Nokso-Koivisto, J. & Chonmaitree, T., Nov 1 2011, In : Journal of Clinical Microbiology. 49, 11, p. 3750-3755 6 p.

Research output: Contribution to journalArticle

91 Scopus citations
2013

Association between body mass index, sexually transmitted infections, and contraceptive compliance

Demaria, A. L., Lugo, J. M., Rahman, M., Pyles, R. B. & Berenson, A. B., Dec 1 2013, In : Journal of Women's Health. 22, 12, p. 1062-1068 7 p.

Research output: Contribution to journalArticle

7 Scopus citations
2011

Innate immune mediator profiles and their regulation in a novel polarized immortalized epithelial cell model derived from human endocervix

Buckner, L. R., Schust, D. J., Ding, J., Nagamatsu, T., Beatty, W., Chang, T. L., Greene, S. J., Lewis, M. E., Ruiz, B., Holman, S. L., Spagnuolo, R. A., Pyles, R. B. & Quayle, A. J., Dec 1 2011, In : Journal of Reproductive Immunology. 92, 1-2, p. 8-20 13 p.

Research output: Contribution to journalArticle

30 Scopus citations
2014

Role of human bocavirus in upper respiratory tract infections and acute otitis media

Nokso-Koivisto, J., Pyles, R. B., Miller, A. L., Jennings, K., Loeffelholz, M. & Chonmaitree, T., 2014, In : Journal of the Pediatric Infectious Diseases Society. 3, 2, p. 98-103 6 p., pit061.

Research output: Contribution to journalArticle

10 Scopus citations
2016

Acute otitis media and other complications of viral respiratory infection

Chonmaitree, T., Trujillo, R., Jennings, K., Alvarez-Fernandez, P., Patel, J. A., Loeffelholz, M. J., Nokso-Koivisto, J., Matalon, R., Pyles, R. B., Miller, A. L. & McCormick, D. P., Apr 2016, In : Pediatrics. 137, 4

Research output: Contribution to journalArticle

34 Scopus citations
2014

Quantification of bacterial uropathogens in preclinical samples using real-time PCR assays

Enderle, J. L., Miller, A. L. & Pyles, R. B., Feb 2014, In : Current Microbiology. 68, 2, p. 220-226 7 p.

Research output: Contribution to journalArticle

6 Scopus citations
2013

Global Expression of Molecular Transporters in the Human Vaginal Tract: Implications for HIV Chemoprophylaxis

Gunawardana, M., Mullen, M., Moss, J. A., Pyles, R. B., Nusbaum, R. J., Patel, J., Vincent, K. L., Wang, C., Guo, C., Yuan, Y. C., Warden, C. D. & Baum, M. M., Oct 15 2013, In : PloS one. 8, 10, e77340.

Research output: Contribution to journalArticle

13 Scopus citations
2017

Prevention of vaginal and rectal HIV transmission by antiretroviral combinations in humanized mice

Gallay, P. A., Chatterji, U., Kirchhoff, A., Gandarilla, A., Gunawardana, M., Pyles, R. B., Marzinke, M. A., Moss, J. A. & Baum, M. M., Sep 2017, In : PloS one. 12, 9, e0184303.

Research output: Contribution to journalArticle

7 Scopus citations
2020

Methylation Patterns of the HTR2A Associate With Relapse-Related Behaviors in Cocaine-Dependent Participants

Land, M. A., Ramesh, D., Miller, A. L., Pyles, R. B., Cunningham, K. A., Moeller, F. G. & Anastasio, N. C., Jun 10 2020, In : Frontiers in Psychiatry. 11, 532.

Research output: Contribution to journalArticle

Open Access
2016

Intraluminal flagellin differentially contributes to gut dysbiosis and systemic inflammation following burn injury

Grimes, L., Doyle, A., Miller, A. L., Pyles, R. B., Olah, G., Szabo, C., Hoskins, S. & Eaves-Pyles, T., Dec 2016, In : PloS one. 11, 12, e0166770.

Research output: Contribution to journalArticle

6 Scopus citations
2015

Symptomatic and asymptomatic respiratory viral infections in the first year of life: Association with acute otitis media development

Chonmaitree, T., Alvarez-Fernandez, P., Jennings, K., Trujillo, R., Marom, T., Loeffelholz, M. J., Miller, A. L., McCormick, D. P., Patel, J. A. & Pyles, R. B., Jan 1 2015, In : Clinical Infectious Diseases. 60, 1, p. 1-9 9 p.

Research output: Contribution to journalArticle

52 Scopus citations