Find Research Outputs

Search in all content

Filters for Publications

Search concepts
Selected Filters

Publication Year

  • 2020
  • 2019
  • 2018
  • 2016
  • 2015
  • 2014
  • 2013
  • 2012
  • 2011

Author

  • Slobodan Paessler
2015
14 Scopus citations
2019
2 Scopus citations
2018

Merimepodib, an IMPDH inhibitor, suppresses replication of Zika virus and other emerging viral pathogens

Tong, X., Smith, J., Bukreyeva, N., Koma, T., Manning, J., Kalkeri, R., Kwong, A. D. & Paessler, S., Jan 1 2018, In : Antiviral Research. 149, p. 34-40 7 p.

Research output: Contribution to journalArticle

21 Scopus citations
2014
64 Scopus citations
2018

Ibuprofen as a template molecule for drug design against Ebola virus

Paessler, S., Huang, C., Sencanski, M., Veljkovic, N., Perovic, V., Glisic, S. & Veljkovic, V., Jan 1 2018, In : Frontiers in Bioscience - Landmark. 23, 5, p. 947-953 7 p.

Research output: Contribution to journalArticle

9 Scopus citations
2012

Junín virus infection activates the type I interferon pathway in a RIG-I-dependent manner

Huang, C., Kolokoltsova, O. A., Yun, N. E., Seregin, A. V., Poussard, A. L., Walker, A. G., Brasier, A. R., Zhao, Y., Tian, B., de la Torre, J. C. & Paessler, S., May 2012, In : PLoS neglected tropical diseases. 6, 5, e1659.

Research output: Contribution to journalArticle

41 Scopus citations
2013

CDK9-dependent transcriptional elongation in the innate interferon-stimulated gene response to respiratory syncytial virus infection in airway epithelial cells

Tian, B., Zhao, Y., Kalita, M., Edeh, C. B., Paessler, S., Casola, A., Teng, M. N., Garofalo, R. P. & Brasier, A. R., Jun 1 2013, In : Journal of virology. 87, 12, p. 7075-7092 18 p.

Research output: Contribution to journalArticle

40 Scopus citations
2012

Resequencing of the puumala virus strain sotkamo from the WHO arbovirus collection

Kurolt, I. C., Paessler, S. & Markotić, A., Oct 1 2012, In : Virus Genes. 45, 2, p. 389-392 4 p.

Research output: Contribution to journalArticle

2011

Rescue from cloned cDNAs and in vivo characterization of recombinant pathogenic romero and live-attenuated candid #1 strains of Junin virus, the causative agent of argentine hemorrhagic fever disease

Emonet, S. F., Seregin, A. V., Yun, N. E., Poussard, A. L., Walker, A. G., De La Torre, J. C. & Paessler, S., Feb 1 2011, In : Journal of virology. 85, 4, p. 1473-1483 11 p.

Research output: Contribution to journalArticle

61 Scopus citations
2012

Control of SIV infection and subsequent induction of pandemic H1N1 immunity in rhesus macaques using an Ad5 [E1-, E2b-] vector platform

Gabitzsch, E. S., Balint-Junior, J. P., Xu, Y., Balcaitis, S., Sanders-Beer, B., Karl, J., Weinhold, K. J., Paessler, S. & Jones, F. R., Nov 26 2012, In : Vaccine. 30, 50, p. 7265-7270 6 p.

Research output: Contribution to journalArticle

8 Scopus citations
2013

Pathogenesis of the viral hemorrhagic fevers

Paessler, S. & Walker, D. H., Jan 2013, In : Annual Review of Pathology: Mechanisms of Disease. 8, p. 411-440 30 p.

Research output: Contribution to journalReview article

147 Scopus citations
2018

Cocaine evokes a profile of oxidative stress and impacts innate antiviral response pathways in astrocytes

Cisneros, I., Erdenizmenli, M., Cunningham, K., Paessler, S. & Dineley, K., Jun 1 2018, In : Neuropharmacology. 135, p. 431-443 13 p.

Research output: Contribution to journalArticle

6 Scopus citations
2013

Mice lacking functional STAT1 are highly susceptible to lethal infection with Lassa virus

Yun, N. E., Seregin, A. V., Walker, D. H., Popov, V. L., Walker, A. G., Smith, J. N., Miller, M., de la Torre, J. C., Smith, J. K., Borisevich, V., Fair, J. N., Wauquier, N., Grant, D. S., Bockarie, B., Bente, D. & Paessler, S., Oct 28 2013, In : Journal of virology. 87, 19, p. 10908-10911 4 p.

Research output: Contribution to journalArticle

30 Scopus citations
2012

Neuropathology of H5N1 virus infection in ferrets

Peng, B. H., Yun, N. E., Chumakova, O., Zacks, M., Campbell, G., Smith, J., Smith, J., Linde, S., Linde, J. & Paessler, S., May 4 2012, In : Veterinary Microbiology. 156, 3-4, p. 294-304 11 p.

Research output: Contribution to journalArticle

8 Scopus citations
2019
Open Access
1 Scopus citations
2020

Fentanyl self-administration impacts brain immune responses in male Sprague-Dawley rats

Ezeomah, C., Cunningham, K. A., Stutz, S. J., Fox, R. G., Bukreyeva, N., Dineley, K. T., Paessler, S. & Cisneros, I. E., Jul 2020, In : Brain, Behavior, and Immunity. 87, p. 725-738 14 p.

Research output: Contribution to journalArticle

1 Scopus citations
2018

Using electronic biology based platform to predict flu vaccine efficacy for 2018/2019

Veljkovic, V. & Paessler, S., Jan 1 2018, In : F1000Research. 7, 298.

Research output: Contribution to journalArticle

3 Scopus citations
2019

Lethal infection of Lassa virus isolated from a human clinical sample in outbred guinea pigs without adaptation

Maruyama, J., Manning, J. T., Mateer, E. J., Sattler, R., Bukreyeva, N., Huang, C. & Paessler, S., Jan 1 2019, In : mSphere. 4, 5, e00428-19.

Research output: Contribution to journalArticle

Open Access
2 Scopus citations
2015

The glycoprotein precursor gene of Junin virus determines the virulence of the romero strain and the attenuation of the Candid #1 strain in a representative animal model of Argentine hemorrhagic fever

Seregin, A. V., Yun, N. E., Miller, M., Aronson, J., Smith, J. K., Walker, A. G., Smith, J. N., Huang, C., Manning, J., de la Torre, J. C. & Paessler, S., 2015, In : Journal of Virology. 89, 11, p. 5949-5956 8 p.

Research output: Contribution to journalArticle

21 Scopus citations
2012

Natural killer cell mediated pathogenesis determines outcome of central nervous system infection with Venezuelan equine encephalitis virus in C3H/HeN mice

Taylor, K., Kolokoltsova, O., Patterson, M., Poussard, A., Smith, J., Estes, D. M. & Paessler, S., Jun 8 2012, In : Vaccine. 30, 27, p. 4095-4105 11 p.

Research output: Contribution to journalArticle

13 Scopus citations

Effect of Ribavirin on Junin Virus Infection in Guinea Pigs

Salazar, M., Yun, N. E., Poussard, A. L., Smith, J. N., Smith, J. K., Kolokoltsova, O. A., Patterson, M. J., Linde, J. & Paessler, S., Jun 1 2012, In : Zoonoses and Public Health. 59, 4, p. 278-285 8 p.

Research output: Contribution to journalArticle

13 Scopus citations
2018

Zika virus infection elicits auto-antibodies to C1q

Koma, T., Veljkovic, V., Anderson, D. E., Wang, L. F., Rossi, S. L., Shan, C., Shi, P. Y., Beasley, D. W., Bukreyeva, N., Smith, J. N., Hallam, S., Huang, C., Von Messling, V. & Paessler, S., Dec 1 2018, In : Scientific reports. 8, 1, 1882.

Research output: Contribution to journalArticle

9 Scopus citations
2013

Production of IL-8, IL-17, IFN-gamma and IP-10 in human astrocytes correlates with alphavirus attenuation

Peng, B. H., Borisevich, V., Popov, V. L., Zacks, M. A., Estes, D. M., Campbell, G. A. & Paessler, S., May 3 2013, In : Veterinary Microbiology. 163, 3-4, p. 223-234 12 p.

Research output: Contribution to journalArticle

6 Scopus citations

Pathogenesis of Venezuelan equine encephalitis

Taylor, K. G. & Paessler, S., Nov 29 2013, In : Veterinary Microbiology. 167, 1-2, p. 145-150 6 p.

Research output: Contribution to journalArticle

22 Scopus citations
2014

Epidemiology and pathogenesis of Bolivian hemorrhagic fever

Patterson, M., Grant, A. & Paessler, S., Apr 2014, In : Current Opinion in Virology. 5, 1, p. 82-90 9 p.

Research output: Contribution to journalReview article

22 Scopus citations
2020

Antiviral activities of type I interferons to SARS-CoV-2 infection

Mantlo, E., Bukreyeva, N., Maruyama, J., Paessler, S. & Huang, C., Jul 2020, In : Antiviral research. 179, 104811.

Research output: Contribution to journalArticle

Open Access
15 Scopus citations
2019

Lassa virus diversity and feasibility for universal prophylactic vaccine [version 1; referees: 3 approved]

Lukashevich, I. S., Paessler, S. & de la Torre, J. C., Jan 1 2019, In : F1000Research. 8, 134.

Research output: Contribution to journalReview article

3 Scopus citations
2020

The Glycoprotein of the Live-Attenuated Junin Virus Vaccine Strain Induces Endoplasmic Reticulum Stress and Forms Aggregates prior to Degradation in the Lysosome

Manning, J. T., Yun, N. E., Seregin, A. V., Koma, T., Sattler, R. A., Ezeomah, C., Huang, C., de la Torre, J. C. & Paessler, S., Mar 31 2020, In : Journal of virology. 94, 8

Research output: Contribution to journalArticle

2011

Prevention of influenza virus shedding and protection from lethal H1N1 challenge using a consensus 2009 H1N1 HA and NA adenovirus vector vaccine

Jones, F. R., Gabitzsch, E. S., Xu, Y., Balint, J. P., Borisevich, V., Smith, J., Smith, J., Peng, B. H., Walker, A., Salazar, M. & Paessler, S., Sep 16 2011, In : Vaccine. 29, 40, p. 7020-7026 7 p.

Research output: Contribution to journalArticle

17 Scopus citations

Vγ4+ T cells regulate host immune response to West Nile virus infection

Welte, T., Aronson, J., Gong, B., Rachamallu, A., Mendell, N., Tesh, R., Paessler, S., Born, W. K., O'Brien, R. L. & Wang, T., Nov 1 2011, In : FEMS Immunology and Medical Microbiology. 63, 2, p. 183-192 10 p.

Research output: Contribution to journalArticle

24 Scopus citations
2015

Highly pathogenic New World and Old World human arenaviruses induce distinct interferon responses in human cells

Huang, C., Kolokoltsova, O. A., Yun, N. E., Seregin, A. V., Ronca, S., Koma, T. & Paessler, S., 2015, In : Journal of virology. 89, 14, p. 7079-7088 10 p.

Research output: Contribution to journalArticle

19 Scopus citations
2016

Characterization of a novel murine model to study zika virus

Rossi, S. L., Tesh, R. B., Azar, S. R., Muruato, A. E., Hanley, K. A., Auguste, A. J., Langsjoen, R. M., Paessler, S., Vasilakis, N. & Weaver, S. C., Jun 1 2016, In : American Journal of Tropical Medicine and Hygiene. 94, 6, p. 1362-1369 8 p.

Research output: Contribution to journalArticle

291 Scopus citations
2012

Junín virus pathogenesis and virus replication

Grant, A., Seregin, A., Huang, C., Kolokoltsova, O., Brasier, A., Peters, C. & Paessler, S., Oct 2012, In : Viruses. 4, 10, p. 2317-2339 23 p.

Research output: Contribution to journalReview article

39 Scopus citations
2019

Differential immune responses to hemorrhagic Fever-Causing arenaviruses

Mantlo, E., Paessler, S. & Huang, C., Dec 2019, In : Vaccines. 7, 4, 138.

Research output: Contribution to journalReview article

Open Access
2012

In vivo imaging systems (IVIS) detection of a neuro-invasive encephalitic virus.

Poussard, A., Patterson, M., Taylor, K., Seregin, A., Smith, J., Smith, J., Salazar, M. & Paessler, S., 2012, In : Journal of visualized experiments : JoVE. 70, p. e4429

Research output: Contribution to journalArticle

9 Scopus citations
2016

The Ectodomain of Glycoprotein from the Candid#1 Vaccine Strain of Junin Virus Rendered Machupo Virus Partially Attenuated in Mice Lacking IFN-αβ/γ Receptor

Koma, T., Huang, C., Aronson, J. F., Walker, A. G., Miller, M., Smith, J. N., Patterson, M. & Paessler, S., Aug 30 2016, In : PLoS neglected tropical diseases. 10, 8, e0004969.

Research output: Contribution to journalArticle

4 Scopus citations
2019

Adenoviral vector-based vaccine is fully protective against lethal Lassa fever challenge in Hartley guinea pigs

Maruyama, J., Mateer, E. J., Manning, J. T., Sattler, R., Seregin, A. V., Bukreyeva, N., Jones, F. R., Balint, J. P., Gabitzsch, E. S., Huang, C. & Paessler, S., Oct 23 2019, In : Vaccine. 37, 45, p. 6824-6831 8 p.

Research output: Contribution to journalArticle

1 Scopus citations
2020

Monoclonal Antibodies with Neutralizing Activity and Fc-Effector Functions against the Machupo Virus Glycoprotein

Amanat, F., Duehr, J., Huang, C., Paessler, S., Tan, G. S. & Krammer, F., Feb 14 2020, In : Journal of virology. 94, 5

Research output: Contribution to journalArticle

1 Scopus citations
2018
Open Access
1 Scopus citations
2014

Reactive astrogliosis in response to hemorrhagic fever virus: Microarray profile of Junin virus-infected human astrocytes

Kolokoltsova, O. A., Yun, N. E. & Paessler, S., Jul 11 2014, In : Virology journal. 11, 1, 126.

Research output: Contribution to journalArticle

4 Scopus citations
2018

Lassa fever–induced sensorineural hearing loss: A neglected public health and social burden

Mateer, E. J., Huang, C., Shehu, N. Y. & Paessler, S., Feb 22 2018, In : PLoS neglected tropical diseases. 12, 2, e0006187.

Research output: Contribution to journalReview article

29 Scopus citations

Review of mammarenavirus biology and replication

Hallam, S. J., Koma, T., Maruyama, J. & Paessler, S., Aug 3 2018, In : Frontiers in Microbiology. 9, AUG, 1751.

Research output: Contribution to journalShort survey

12 Scopus citations
2015

PARP9-DTX3L ubiquitin ligase targets host histone H2BJ and viral 3C protease to enhance interferon signaling and control viral infection

Zhang, Y., Mao, D., Roswit, W. T., Jin, X., Patel, A. C., Patel, D. A., Agapov, E., Wang, Z., Tidwell, R. M., Atkinson, J. J., Huang, G., McCarthy, R., Yu, J., Yun, N. E., Paessler, S., Lawson, T. G., Omattage, N. S., Brett, T. J. & Holtzman, M. J., Dec 1 2015, In : Nature Immunology. 16, 12, p. 1215-1227 13 p.

Research output: Contribution to journalArticle

46 Scopus citations
2014

A viral RNA structural element alters host recognition of nonself RNA

Hyde, J. L., Gardner, C. L., Kimura, T., White, J. P., Liu, G., Trobaugh, D. W., Huang, C., Tonelli, M., Paessler, S., Takeda, K., Klimstra, W. B., Amarasinghe, G. K. & Diamond, M. S., Jan 1 2014, In : Science. 343, 6172, p. 783-787 5 p.

Research output: Contribution to journalArticle

80 Scopus citations
2012

Viral Hemorrhagic Fevers: South American Hemorrhagic Fevers

Paessler, S., Nov 1 2012, Hunter's Tropical Medicine and Emerging Infectious Disease: Ninth Edition. Elsevier Inc., p. 328-330 3 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

2018

Vaccine-elicited receptor-binding site antibodies neutralize two New World hemorrhagic fever arenaviruses

Clark, L. E., Mahmutovic, S., Raymond, D. D., Dilanyan, T., Koma, T., Manning, J. T., Shankar, S., Levis, S. C., Briggiler, A. M., Enria, D. A., Wucherpfennig, K. W., Paessler, S. & Abraham, J., Dec 1 2018, In : Nature communications. 9, 1, 1884.

Research output: Contribution to journalArticle

8 Scopus citations
4 Scopus citations
2015

Improving attrition rates in Ebola virus drug discovery

Glisic, S., Paessler, S., Veljkovic, N., Perovic, V. R., Prljic, J. & Veljkovic, V., Sep 2 2015, In : Expert Opinion on Drug Discovery. 10, 9, p. 1025-1032 8 p.

Research output: Contribution to journalArticle

5 Scopus citations
2016

Neurological sequelae resulting from encephalitic alphavirus infection

Ronca, S. E., Dineley, K. & Paessler, S., 2016, In : Frontiers in Microbiology. 7, JUN, 959.

Research output: Contribution to journalReview article

22 Scopus citations
2011

Rapid, non-invasive imaging of alphaviral brain infection: Reducing animal numbers and morbidity to identify efficacy of potential vaccines and antivirals

Patterson, M., Poussard, A., Taylor, K., Seregin, A., Smith, J., Peng, B. H., Walker, A., Linde, J., Smith, J., Salazar, M. & Paessler, S., Nov 21 2011, In : Vaccine. 29, 50, p. 9345-9351 7 p.

Research output: Contribution to journalArticle

14 Scopus citations