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  • Nisha Garg
2013

Innate Immune Responses and Antioxidant/Oxidant Imbalance Are Major Determinants of Human Chagas Disease

Dhiman, M., Coronado, Y. A., Vallejo, C. K., Petersen, J. R., Ejilemele, A., Nuñez, S., Zago, M. P., Spratt, H. & Garg, N. J., Aug 2013, In : PLoS neglected tropical diseases. 7, 8, e2364.

Research output: Contribution to journalArticle

21 Scopus citations
2020
Open Access
2016

Chemotherapeutic Efficacy of Phosphodiesterase Inhibitors in Chagasic Cardiomyopathy

Wen, J. J., Wan, X., Thacker, J. & Garg, N., Jun 1 2016, In : JACC: Basic to Translational Science. 1, 4, p. 235-250 16 p.

Research output: Contribution to journalReview article

13 Scopus citations
2018
12 Scopus citations

Efficacy of recombinase polymerase amplification to diagnose trypanosoma cruzi infection in dogs with cardiac alterations from an endemic Area of Mexico

Jimenez-Coello, M., Shelite, T., Castellanos, A., Saldarriaga, O., Rivero, R., Ortega-Pacheco, A., Acevedo-Arcique, C., Amaya-Guardia, K., Garg, N., Melby, P. & Travi, B., Aug 1 2018, In : Vector-Borne and Zoonotic Diseases. 18, 8, p. 417-423 7 p.

Research output: Contribution to journalArticle

6 Scopus citations
2016
30 Scopus citations
2019

Immunity and vaccine development efforts against Trypanosoma cruzi

Rios, L. E., Vázquez-Chagoyán, J. C., Pacheco, A. O., Zago, M. P. & Garg, N. J., Dec 2019, In : Acta Tropica. 200, 105168.

Research output: Contribution to journalReview article

5 Scopus citations
2020
Open Access
1 Scopus citations
2014
15 Scopus citations

Hepatotoxicity in Mice of a Novel Anti-parasite Drug Candidate Hydroxymethylnitrofurazone: A Comparison with Benznidazole

Davies, C., Dey, N., Negrette, O. S., Parada, L. A., Basombrio, M. A. & Garg, N. J., Jan 1 2014, In : PLoS neglected tropical diseases. 8, 10

Research output: Contribution to journalArticle

12 Scopus citations
2016

S-Nitrosylation Proteome Profile of Peripheral Blood Mononuclear Cells in Human Heart Failure

Koo, S. J., Spratt, H. M., Soman, K. V., Stafford, S., Gupta, S., Petersen, J. R., Zago, M. P., Kuyumcu-Martinez, M. N., Brasier, A., Wiktorowicz, J. E. & Garg, N. J., Jan 1 2016, In : International Journal of Proteomics. 2016, 1384523.

Research output: Contribution to journalArticle

11 Scopus citations
2013

Antigenicity and Diagnostic Potential of Vaccine Candidates in Human Chagas Disease

Gupta, S., Wan, X., Zago, M. P., Martinez Sellers, V. C., Silva, T. S., Assiah, D., Dhiman, M., Nuñez, S., Petersen, J. R., Vázquez-Chagoyán, J. C., Estrada-Franco, J. G. & Garg, N. J., Jan 2013, In : PLoS neglected tropical diseases. 7, 1, e2018.

Research output: Contribution to journalArticle

16 Scopus citations
2019

Trypanothione synthetase confers growth, survival advantage and resistance to anti-protozoal drugs in Trypanosoma cruzi

Mesías, A. C., Sasoni, N., Arias, D. G., Pérez Brandán, C., Orban, O. C. F., Kunick, C., Robello, C., Comini, M. A., Garg, N. & Zago, M. P., Jan 1 2019, In : Free Radical Biology and Medicine. 130, p. 23-34 12 p.

Research output: Contribution to journalArticle

3 Scopus citations
2012

Defects of mtDNA replication impaired mitochondrial biogenesis during Trypanosoma cruzi infection in human cardiomyocytes and chagasic patients: the role of Nrf1/2 and antioxidant response.

Wan, X., Gupta, S., Zago, M. P., Davidson, M. M., Dousset, P., Amoroso, A. & Garg, N. J., Dec 2012, In : Unknown Journal. 1, 6, p. e003855

Research output: Contribution to journalArticle

31 Scopus citations
2017
18 Scopus citations
2020
2 Scopus citations
2018

Pathogenesis of Chronic Chagas Disease: Macrophages, Mitochondria, and Oxidative Stress

Lopez, M., Tanowitz, H. B. & Garg, N., Mar 1 2018, In : Current Clinical Microbiology Reports. 5, 1, p. 45-54 10 p.

Research output: Contribution to journalReview article

17 Scopus citations
2011

Global health: Neglected diseases and access to medicines

Garg, N. J., Sep 1 2011, In : Infectious disease clinics of North America. 25, 3, p. 639-651 13 p.

Research output: Contribution to journalReview article

2 Scopus citations
2016

Dysregulation of RBFOX2 Is an Early Event in Cardiac Pathogenesis of Diabetes

Nutter, C. A., Jaworski, E. A., Verma, S. K., Deshmukh, V., Wang, Q., Botvinnik, O. B., Lozano, M. J., Abass, I. J., Ijaz, T., Brasier, A. R., Garg, N., Wehrens, X. H. T., Yeo, G. W. & Martinez, N., Jun 7 2016, In : Cell Reports. 15, 10, p. 2200-2213 14 p.

Research output: Contribution to journalArticle

24 Scopus citations

Changes in Proteome Profile of Peripheral Blood Mononuclear Cells in Chronic Chagas Disease

Garg, N., Soman, K. V., Zago, M. P., Koo, S. J., Spratt, H., Stafford, S., Blell, Z. N., Gupta, S., Nuñez Burgos, J., Barrientos, N., Brasier, A. R. & Wiktorowicz, J. E., Feb 26 2016, In : PLoS Neglected Tropical Diseases. 10, 2, e0004490.

Research output: Contribution to journalArticle

14 Scopus citations
2013

Leishmania amazonensis amastigotes trigger neutrophil activation but resist neutrophil microbicidal mechanisms

Carlsen, E. D., Hay, C., Henard, C. A., Popov, V., Garg, N. J. & Soong, L., Nov 1 2013, In : Infection and immunity. 81, 11, p. 3966-3974 9 p.

Research output: Contribution to journalArticle

23 Scopus citations
2011

Testing the efficacy of a multi-component DNA-prime/DNA-boost vaccine against Trypanosoma cruzi infection in dogs

Aparicio-Burgos, J. E., Ochoa-García, L., Zepeda-Escobar, J. A., Gupta, S., Dhiman, M., Martínez, J. S., de Oca-Jiménez, R. M., Arreola, M. V., Barbabosa-Pliego, A., Vázquez-Chagoyán, J. C. & Garg, N. J., May 2011, In : PLoS neglected tropical diseases. 5, 5, e1050.

Research output: Contribution to journalArticle

29 Scopus citations
2014

Caspase-1/ASC inflammasome-mediated activation of IL-1β-ROS-NF-κB pathway for control of Trypanosoma cruzireplication and survival is dispensable in NLRP3-/- macrophages

Dey, N., Sinha, M., Gupta, S., Gonzalez, M. N., Fang, R., Endsley, J. J., Luxon, B. A. & Garg, N. J., Nov 5 2014, In : PloS one. 9, 11, e111539.

Research output: Contribution to journalArticle

28 Scopus citations
2011

Vaccine Development Against Trypanosoma cruzi and Chagas Disease

Vázquez-Chagoyán, J. C., Gupta, S. & Garg, N. J., 2011, Advances in Parasitology. Academic Press, p. 121-146 26 p. (Advances in Parasitology; vol. 75).

Research output: Chapter in Book/Report/Conference proceedingChapter

46 Scopus citations
2013

Granulocyte colony-stimulating factor partially repairs the damage provoked by Trypanosoma cruzi in murine myocardium

González, M. N., Dey, N., Garg, N. J. & Postan, M., Oct 3 2013, In : International Journal of Cardiology. 168, 3, p. 2567-2574 8 p.

Research output: Contribution to journalArticle

7 Scopus citations
2019

Atg5 Supports Rickettsia australis Infection in Macrophages In Vitro and In Vivo

Bechelli, J., Vergara, L., Smalley, C., Buzhdygan, T. P., Bender, S., Zhang, W., Liu, Y., Popov, V., Wang, J., Garg, N., Hwang, S., Walker, D. & Fang, R., Jan 1 2019, In : Infection and Immunity. 87, 1

Research output: Contribution to journalArticle

7 Scopus citations
2013
Open Access
21 Scopus citations
2016

Editorial commentary: Targeting Chagas disease

Tanowitz, H. B. & Garg, N., 2016, (Accepted/In press) In : Trends in Cardiovascular Medicine.

Research output: Contribution to journalArticle

2018
6 Scopus citations
2012

Mechanisms of Trypanosoma cruzi persistence in Chagas disease

Nagajyothi, F., Machado, F. S., Burleigh, B. A., Jelicks, L. A., Scherer, P. E., Mukherjee, S., Lisanti, M. P., Weiss, L. M., Garg, N. J. & Tanowitz, H. B., May 1 2012, In : Cellular Microbiology. 14, 5, p. 634-643 10 p.

Research output: Contribution to journalReview article

80 Scopus citations

Current understanding of immunity to Trypanosoma cruzi infection and pathogenesis of Chagas disease

Machado, F. S., Dutra, W. O., Esper, L., Gollob, K. J., Teixeira, M. M., Factor, S. M., Weiss, L. M., Nagajyothi, F., Tanowitz, H. B. & Garg, N. J., Nov 1 2012, In : Seminars in Immunopathology. 34, 6, p. 753-770 18 p.

Research output: Contribution to journalReview article

112 Scopus citations
2020

Genes of the cGMP-PKG-Ca2+ signaling pathway are alternatively spliced in cardiomyopathy: Role of RBFOX2

Wan, X., Belanger, K. A., Widen, S. G., Kuyumcu-Martinez, M. N. & Garg, N. J., Mar 1 2020, In : Biochimica et Biophysica Acta - Molecular Basis of Disease. 1866, 3, 165620.

Research output: Contribution to journalArticle

2017

Gene Expression Profiling and Functional Characterization of Macrophages in Response to Circulatory Microparticles Produced during Trypanosoma cruzi Infection and Chagas Disease

Chowdhury, I. H., Koo, S. J., Gupta, S., Liang, L. Y., Bahar, B., Silla, L., Nuñez-Burgos, J., Barrientos, N., Zago, M. P. & Garg, N. J., Feb 1 2017, In : Journal of Innate Immunity. 9, 2, p. 203-216 14 p.

Research output: Contribution to journalArticle

13 Scopus citations
2019

TcG2/TcG4 DNA Vaccine Induces Th1 Immunity against Acute Trypanosoma cruzi Infection: Adjuvant and antigenic effects of heterologous T. Rangeli Booster Immunization

Gupta, S., Salgado-Jiménez, B., Lokugamage, N., Vázquez-Chagoyán, J. C. & Garg, N. J., Jan 1 2019, In : Frontiers in immunology. 10, JUN, 1456.

Research output: Contribution to journalArticle

Open Access
2 Scopus citations

Pathology and Pathogenesis of Chagas Heart Disease

Bonney, K. M., Luthringer, D. J., Kim, S. A., Garg, N. J. & Engman, D. M., 2019, In : Annual Review of Pathology: Mechanisms of Disease. 14, p. 421-447 27 p.

Research output: Contribution to journalReview article

27 Scopus citations
2012
10 Scopus citations
2018

Pentose phosphate shunt modulates reactive oxygen species and nitric oxide production controlling Trypanosoma cruzi in Macrophages

Koo, S. J., Szczesny, B., Wan, X., Putluri, N. & Garg, N. J., Feb 16 2018, In : Frontiers in immunology. 9, FEB, 202.

Research output: Contribution to journalArticle

10 Scopus citations
2019

TcVac1 vaccine delivery by intradermal electroporation enhances vaccine induced immune protection against Trypanosoma cruzi infection in mice

Hegazy-Hassan, W., Zepeda-Escobar, J. A., Ochoa-García, L., Contreras-Ortíz, J. M. E., Tenorio-Borroto, E., Barbabosa-Pliego, A., Aparicio-Burgos, J. E., Oros-Pantoja, R., Rivas-Santiago, B., Díaz-Albiter, H., Garg, N. & Vázquez-Chagoyán, J. C., Jan 7 2019, In : Vaccine. 37, 2, p. 248-257 10 p.

Research output: Contribution to journalArticle

4 Scopus citations

Metabolic programming of macrophage functions and pathogens control

Koo, S. J. & Garg, N., Jun 1 2019, In : Redox Biology. 24, 101198.

Research output: Contribution to journalReview article

Open Access
8 Scopus citations
2016

Macrophages promote oxidative metabolism to drive nitric oxide generation in response to Trypanosoma cruzi

Koo, S. J., Chowdhury, I. H., Szczesny, B., Wan, X. & Garg, N. J., Jan 1 2016, In : Infection and immunity. 84, 12, p. 3527-3541 15 p.

Research output: Contribution to journalArticle

16 Scopus citations
2019

Redox Balance Keepers and Possible Cell Functions Managed by Redox Homeostasis in Trypanosoma cruzi

Mesías, A. C., Garg, N. J. & Zago, M. P., Dec 20 2019, In : Frontiers in Cellular and Infection Microbiology. 9, 435.

Research output: Contribution to journalReview article

Open Access
2 Scopus citations

Potential utility of protein targets of cysteine-s-nitrosylation in identifying clinical disease status in human chagas disease

Zago, M. P., Wiktorowicz, J. E., Spratt, H., Koo, S. J., Barrientos, N., Burgos, A. N., Burgos, J. N., Iñiguez, F., Botelli, V., De La Fuente, R. L. & Garg, N. J., 2019, In : Frontiers in Microbiology. 10, JAN, 3320.

Research output: Contribution to journalArticle

Open Access
2 Scopus citations
2018

Early Trypanosoma cruzi infection triggers mTORC1-mediated respiration increase and mitochondrial biogenesis in human primary cardiomyocytes

Libisch, M. G., Faral-Tello, P., Garg, N. J., Radi, R., Piacenza, L. & Robello, C., Aug 16 2018, In : Frontiers in Microbiology. 9, AUG, 1889.

Research output: Contribution to journalArticle

3 Scopus citations
2011

NADPH oxidase inhibition ameliorates Trypanosoma cruzi-induced myocarditis during Chagas disease

Dhiman, M. & Garg, N. J., Dec 2011, In : Journal of Pathology. 225, 4, p. 583-596 14 p.

Research output: Contribution to journalArticle

59 Scopus citations
2017

Protein Cysteinyl-S-Nitrosylation: Analysis and Quantification

Wiktorowicz, J. E., Stafford, S. J. & Garg, N., 2017, Methods in Enzymology. Academic Press Inc., Vol. 586. p. 1-14 14 p. (Methods in Enzymology; vol. 586).

Research output: Chapter in Book/Report/Conference proceedingChapter

4 Scopus citations
2014

Markers of oxidative stress in adipose tissue during Trypanosoma cruzi infection

Wen, J. J., Nagajyothi, F., Machado, F. S., Weiss, L. M., Scherer, P. E., Tanowitz, H. B. & Garg, N., Sep 1 2014, In : Parasitology Research. 113, 9, p. 3159-3165 7 p.

Research output: Contribution to journalArticle

16 Scopus citations
2019

Fluorescence proteomic technology to analyze peripheral blood mononuclear cells in chronic chagas disease

Wiktorowicz, J. E., Zago, M. P. & Garg, N., Jan 1 2019, Methods in Molecular Biology. Humana Press Inc., p. 363-380 18 p. (Methods in Molecular Biology; vol. 1955).

Research output: Chapter in Book/Report/Conference proceedingChapter

2011

ROS Signalling of inflammatory cytokines during trypanosoma cruzi infection

Gupta, S., Dhiman, M., Wen, J. J. & Garg, N. J., 2011, Advances in Parasitology. Academic Press, p. 153-170 18 p. (Advances in Parasitology; vol. 76).

Research output: Chapter in Book/Report/Conference proceedingChapter

30 Scopus citations
2020

Potential Role of Antioxidants as Adjunctive Therapy in Chagas Disease

Sánchez-Villamil, J. P., Bautista-Ninõ, P. K., Serrano, N. C., Rincon, M. Y. & Garg, N. J., Jan 1 2020, In : Oxidative medicine and cellular longevity. 2020, 9081813.

Research output: Contribution to journalReview article

Open Access
2016

Trypanosoma cruzi and Chagas Disease: Innate Immunity, ROS, and Cardiovascular System

Tanowitz, H. B., Wen, J. J., Machado, F. S., Desruisseaux, M. S., Robello, C. & Garg, N. J., Jan 1 2016, Vascular Responses to Pathogens. Elsevier Inc., p. 183-193 11 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

6 Scopus citations