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  • Thomas Smith
2011

Structural studies on antibody recognition and neutralization of viruses

Smith, T. J., Aug 2011, In : Current Opinion in Virology. 1, 2, p. 150-156 7 p.

Research output: Contribution to journalReview article

6 Scopus citations
2019

Glutamate Dehydrogenase, a Complex Enzyme at a Crucial Metabolic Branch Point

Smith, H. Q., Li, C., Stanley, C. A. & Smith, T. J., Jan 15 2019, In : Neurochemical Research. 44, 1, p. 117-132 16 p.

Research output: Contribution to journalArticle

9 Scopus citations

Bile Salts Alter the Mouse Norovirus Capsid Conformation: Possible Implications for Cell Attachment and Immune Evasion

Sherman, M. B., Williams, A. N., Smith, H. Q., Nelson, C., Wilen, C. B., Fremont, D. H., Virgin, H. W. & Smith, T. J., Oct 1 2019, In : Journal of virology. 93, 19

Research output: Contribution to journalArticle

9 Scopus citations
2013

Structural and functional studies of a phosphatidic acid-binding antifungal plant defensin MtDef4: Identification of an RGFRRR motif governing fungal cell entry

Sagaram, U. S., El-Mounadi, K., Buchko, G. W., Berg, H. R., Kaur, J., Pandurangi, R. S., Smith, T. J. & Shah, D. M., Dec 4 2013, In : PloS one. 8, 12, e82485.

Research output: Contribution to journalArticle

76 Scopus citations
2012

Protruding domain of capsid protein is necessary and sufficient to determine murine norovirus replication and pathogenesis in vivo

Strong, D. W., Thackray, L. B., Smith, T. J. & Virgin, H. W., Mar 1 2012, In : Journal of virology. 86, 6, p. 2950-2958 9 p.

Research output: Contribution to journalArticle

53 Scopus citations
2011

Glutamate dehydrogenase

Smith, T. J. & Stanley, C. A., Nov 24 2011, Amino Acids in Human Nutrition and Health. CABI Publishing, p. 1-23 23 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

2019

Dissecting the Antenna in Human Glutamate Dehydrogenase: Understanding Its Role in Subunit Communication and Allosteric Regulation

Hoffpauir, Z. A., Sherman, E. & Smith, T. J., Oct 15 2019, In : Biochemistry. 58, 41, p. 4195-4206 12 p.

Research output: Contribution to journalArticle

2011

Transgenic maize plants expressing the Totivirus antifungal protein, KP4, are highly resistant to corn smut

Allen, A., Islamovic, E., Kaur, J., Gold, S., Shah, D. & Smith, T. J., Oct 2011, In : Plant Biotechnology Journal. 9, 8, p. 857-864 8 p.

Research output: Contribution to journalArticle

22 Scopus citations
2012

The structure and allosteric regulation of mammalian glutamate dehydrogenase

Li, M., Li, C., Allen, A., Stanley, C. A. & Smith, T. J., Mar 15 2012, In : Archives of Biochemistry and Biophysics. 519, 2, p. 69-80 12 p.

Research output: Contribution to journalReview article

77 Scopus citations
2011

The structure and allosteric regulation of glutamate dehydrogenase

Li, M., Li, C., Allen, A., Stanley, C. A. & Smith, T. J., Sep 2011, In : Neurochemistry International. 59, 4, p. 445-455 11 p.

Research output: Contribution to journalReview article

28 Scopus citations

A novel mechanism of V-type zinc inhibition of glutamate dehydrogenase results from disruption of subunit interactions necessary for efficient catalysis

Bailey, J., Powell, L., Sinanan, L., Neal, J., Li, M., Smith, T. & Bell, E., Sep 2011, In : FEBS Journal. 278, 17, p. 3140-3151 12 p.

Research output: Contribution to journalArticle

6 Scopus citations

Structure-activity determinants in antifungal plant defensins msdef1 and mtdef4 with different modes of action against fusarium graminearum

Sagaram, U. S., Pandurangi, R., Kaur, J., Smith, T. J. & Shah, D. M., 2011, In : PloS one. 6, 4, e18550.

Research output: Contribution to journalArticle

98 Scopus citations

Green tea polyphenols control dysregulated glutamate dehydrogenase in transgenic mice by hijacking the ADP activation site

Li, C., Li, M., Chen, P., Narayan, S., Matschinsky, F. M., Bennett, M. J., Stanley, C. A. & Smith, T. J., Oct 30 2011, In : Journal of Biological Chemistry. 286, 39, p. 34164-34174 11 p.

Research output: Contribution to journalArticle

47 Scopus citations
2017

Antibody-induced uncoating of human rhinovirus B14

Dong, Y., Liu, Y., Jiang, W., Smith, T. J., Xu, Z. & Rossmann, M. G., Jul 25 2017, In : Proceedings of the National Academy of Sciences of the United States of America. 114, 30, p. 8017-8022 6 p.

Research output: Contribution to journalArticle

26 Scopus citations
2011

Atomic structure of salutaridine reductase from the opium poppy (Papaver somniferum)

Higashi, Y., Kutchan, T. M. & Smith, T. J., Feb 25 2011, In : Journal of Biological Chemistry. 286, 8, p. 6532-6541 10 p.

Research output: Contribution to journalArticle

10 Scopus citations
2012

Multidomain carbohydrate-binding proteins involved in Bacteroides thetaiotaomicron starch metabolism

Cameron, E. A., Maynard, M. A., Smith, C. J., Smith, T. J., Koropatkin, N. M. & Martens, E. C., Oct 5 2012, In : Journal of Biological Chemistry. 287, 41, p. 34614-34625 12 p.

Research output: Contribution to journalArticle

54 Scopus citations
2013

The atomic structure of the virally encoded antifungal protein, KP6

Allen, A., Chatt, E. & Smith, T. J., Feb 8 2013, In : Journal of Molecular Biology. 425, 3, p. 609-621 13 p.

Research output: Contribution to journalArticle

2 Scopus citations
2011

Green tea polyphenols in drug discovery: A success or failure?

Smith, T. J., Jun 1 2011, In : Expert Opinion on Drug Discovery. 6, 6, p. 589-595 7 p.

Research output: Contribution to journalReview article

24 Scopus citations
2015

A high-throughput drop microfluidic system for virus culture and analysis

Fischer, A. E., Wu, S. K., Proescher, J. B. G., Rotem, A., Chang, C. B., Zhang, H., Tao, Y., Mehoke, T. S., Thielen, P. M., Kolawole, A. O., Smith, T. J., Wobus, C. E., Weitz, D. A., Lin, J. S., Feldman, A. B. & Wolfe, J. T., Mar 1 2015, In : Journal of Virological Methods. 213, p. 111-117 7 p.

Research output: Contribution to journalArticle

16 Scopus citations
2017

A severe case of hyperinsulinism due to hemizygous activating mutation of glutamate dehydrogenase

Barrosse-Antle, M., Su, C., Chen, P., Boodhansingh, K. E., Smith, T. J., Stanley, C. A., De León, D. D. & Li, C., Dec 2017, In : Pediatric Diabetes. 18, 8, p. 911-916 6 p.

Research output: Contribution to journalArticle

9 Scopus citations
2012

Glutamate dehydrogenase: Structure, regulation, and its role in insulin homeostasis

Smith, T. J., Apr 4 2012, Monogenic Hyperinsulinemic Hypoglycemia Disorders. Charles, S. & Diva, D. L. (eds.). p. 87-99 13 p. (Frontiers in Diabetes; vol. 21).

Research output: Chapter in Book/Report/Conference proceedingChapter

Structural basis for broad detection of genogroup II noroviruses by a monoclonal antibody that binds to a site occluded in the viral particle

Hansman, G. S., Taylor, D. W., McLellan, J. S., Smith, T. J., Georgiev, I., Tame, J. R. H., Park, S. Y., Yamazaki, M., Gondaira, F., Miki, M., Katayama, K., Murata, K. & Kwong, P. D., Apr 2012, In : Journal of virology. 86, 7, p. 3635-3646 12 p.

Research output: Contribution to journalArticle

49 Scopus citations
2013

Green Tea and Control of Glutamate Dehydrogenase Activity

Smith, T. J., Aug 29 2013, Tea in Health and Disease Prevention. Elsevier Inc., p. 1029-1038 10 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

2017

Stability of cucumber necrosis virus at the quasi-6-fold axis affects zoospore transmission

Sherman, M. B., Kakani, K., Rochon, DA., Jiang, W., Voss, N. R. & Smith, T. J., Oct 1 2017, In : Journal of virology. 91, 19, e01030-17.

Research output: Contribution to journalArticle

2 Scopus citations
2013

The virally encoded killer proteins from Ustilago maydis

Allen, A., Islamovic, E., Kaur, J., Gold, S., Shah, D. & Smith, T. J., Jan 1 2013, In : Fungal Biology Reviews. 26, 4, p. 166-173 8 p.

Research output: Contribution to journalReview article

5 Scopus citations

Atomic structure of cucumber necrosis virus and the role of the capsid in vector transmission

Li, M., Kakani, K., Katpally, U., Johnson, S., Rochon, DA. & Smith, T. J., 2013, In : Journal of virology. 87, 22, p. 12166-12175 10 p.

Research output: Contribution to journalArticle

16 Scopus citations
2019

Allosteric discrimination at the NADH/ADP regulatory site of glutamate dehydrogenase

Nassar, O. M., Wong, K. Y., Lynch, G. C., Smith, T. J. & Pettitt, B. M., Dec 1 2019, In : Protein Science. 28, 12, p. 2080-2088 9 p.

Research output: Contribution to journalArticle

3 Scopus citations

The dynamic capsid structures of the noroviruses

Smith, H. Q. & Smith, T. J., Mar 2019, In : Viruses. 11, 3, 235.

Research output: Contribution to journalReview article

Open Access
5 Scopus citations
2017

Norovirus escape from broadly neutralizing antibodies is limited to allostery-like mechanisms

Kolawole, A. O., Smith, H. Q., Svoboda, S. A., Lewis, M. S., Sherman, M. B., Lynch, G. C., Pettitt, B. M., Smith, T. J. & Wobus, C. E., Sep 1 2017, In : mSphere. 2, 5, e00334-17.

Research output: Contribution to journalArticle

18 Scopus citations
2016

Identification of a Novel Activator of Mammalian Glutamate Dehydrogenase

Smith, H. Q. & Smith, T., Nov 29 2016, In : Biochemistry. 55, 47, p. 6568-6576 9 p.

Research output: Contribution to journalArticle

8 Scopus citations