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Author

  • Pomila Singh
2016

CD90+ stromal cells are the major source of IL-6, which supports cancer stem-like cells and inflammation in colorectal cancer

Huynh, P. T., Beswick, E. J., Coronado, Y. A., Johnson, P., O'Connell, M. R., Watts, T., Singh, P., Qiu, S., Morris, K., Powell, D. W. & Pinchuk, I., Apr 15 2016, In : International Journal of Cancer. 138, 8, p. 1971-1981 11 p.

Research output: Contribution to journalArticle

34 Scopus citations
2012

Distinct compartmentalization of NF-κB activity in crypt and crypt-denuded lamina propria precedes and accompanies hyperplasia and/or colitis following bacterial infection

Chandrakesan, P., Ahmed, I., Chinthalapally, A., Singh, P., Awasthi, S., Anant, S. & Umar, S., Feb 1 2012, In : Infection and immunity. 80, 2, p. 753-767 15 p.

Research output: Contribution to journalArticle

24 Scopus citations
2014

Cationic lipid guided short-hairpin RNA interference of annexin A2 attenuates tumor growth and metastasis in a mouse lung cancer stem cell model

Andey, T., Marepally, S., Patel, A., Jackson, T., Sarkar, S., O'Connell, M., Reddy, R. C., Chellappan, S., Singh, P. & Singh, M., Jun 28 2014, In : Journal of Controlled Release. 184, 1, p. 67-78 12 p.

Research output: Contribution to journalArticle

33 Scopus citations

Curcumin promotes autophagic survival of a subset of colon cancer stem cells, which are ablated by DCLK1-siRNA

Kantara, C., O'Connell, M., Sarkar, S., Moya, S., Ullrich, R. & Singh, P., Jan 5 2014, In : Cancer Research. 74, 9, p. 2487-2498 12 p.

Research output: Contribution to journalArticle

73 Scopus citations
2017
14 Scopus citations
2011

Annexin A2 mediates Up-regulation of NF-κB, β-catenin, and stem cell in response to progastrin in mice and HEK-293 cells

Sarkar, S., Swiercz, R., Kantara, C., Hajjar, K. A. & Singh, P., Feb 2011, In : Gastroenterology. 140, 2, p. 583-595.e4

Research output: Contribution to journalArticle

44 Scopus citations
2017

Hormonal effects on gastrointestinal cancer growth

Townsend, C., Singh, P. & Thompson, J. C., Jan 1 2017, Growth of the Gastrointestinal Tract: Gastrointestinal Hormones and Growth Factors. CRC Press, p. 207-221 15 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

2016

Epigenetic regulation of human DCLK-1 gene during coloncarcinogenesis: Clinical and mechanistic implications

Singh, P., O'Connell, M. & Shubhashish, S., Sep 1 2016, In : Stem Cell Investigation. 2016, SEP, 51.

Research output: Contribution to journalReview article

10 Scopus citations
2015

Novel regenerative peptide TP508 mitigates radiation-induced gastrointestinal damage by activating stem cells and preserving crypt integrity

Kantara, C., Moya, S. M., Houchen, C. W., Umar, S., Ullrich, R. L., Singh, P. & Carney, D. H., Nov 1 2015, In : Laboratory Investigation. 95, 11, p. 1222-1233 12 p.

Research output: Contribution to journalArticle

17 Scopus citations
2019

Inhibition of LEF1-mediated DCLK1 by niclosamide attenuates colorectal cancer stemness

Park, S. Y., Kim, J. Y., Choi, J. H., Kim, J. H., Lee, C. J., Singh, P., Sarkar, S., Baek, J. H. & Nam, J. S., Feb 15 2019, In : Clinical Cancer Research. 25, 4, p. 1415-1429 15 p.

Research output: Contribution to journalArticle

7 Scopus citations
2015

Methods for detecting circulating cancer stem cells (CCSCs) as a novel approach for diagnosis of colon cancer relapse/metastasis

Kantara, C., O'Connell, M. R., Luthra, G., Gajjar, A., Sarkar, S., Ullrich, R. L. & Singh, P., Jan 31 2015, In : Laboratory Investigation. 95, 1, p. 100-112 13 p.

Research output: Contribution to journalArticle

42 Scopus citations

Epigenetic changes and alternate promoter usage by human colon cancers for expressing DCLK1-isoforms: Clinical Implications

Oconnell, M. R., Sarkar, S., Luthra, G., Okugawa, Y., Toiyama, Y., Gajjar, A., Qiu, S., Goel, A. & Singh, P., Oct 8 2015, In : Scientific Reports. 5, 14983.

Research output: Contribution to journalArticle

28 Scopus citations
2012

Progastrin overexpression imparts tumorigenic/metastatic potential to embryonic epithelial cells: Phenotypic differences between transformed and nontransformed stem cells

Sarkar, S., Kantara, C., Ortiz, I., Swiercz, R., Kuo, J., Davey, R., Escobar, K., Ullrich, R. & Singh, P., Oct 1 2012, In : International Journal of Cancer. 131, 7, p. E1088-E1099

Research output: Contribution to journalArticle

16 Scopus citations

Clathrin mediates endocytosis of progastrin and activates MAPKs: Role of cell surface annexin A2

Sarkar, S., Kantara, C. & Singh, P., Apr 1 2012, In : American Journal of Physiology - Gastrointestinal and Liver Physiology. 302, 7, p. G712-G722

Research output: Contribution to journalArticle

13 Scopus citations

Progastrin peptides increase the risk of developing colonic tumors: Impact on colonic stem cells

Singh, P., Sarkar, S., Kantara, C. & Maxwell, C., Dec 1 2012, In : Current Colorectal Cancer Reports. 8, 4, p. 277-289 13 p.

Research output: Contribution to journalArticle

13 Scopus citations
2017

FOXD3 regulates csc marker, dclk1-s, and invasive potential: Prognostic implications in colon cancer

Sarkar, S., O'Connell, M. R., Okugawa, Y., Lee, B. S., Toiyama, Y., Kusunoki, M., Daboval, R. D., Goel, A. & Singh, P., Dec 1 2017, In : Molecular Cancer Research. 15, 12, p. 1678-1691 14 p.

Research output: Contribution to journalArticle

10 Scopus citations