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  • Kota Ramana
2017

Aldose reductase inhibitor, fidarestat regulates mitochondrial biogenesis via Nrf2/HO-1/AMPK pathway in colon cancer cells

Shukla, K., Sonowal, H., Saxena, A., Ramana, K. & Srivastava, S., Dec 28 2017, In : Cancer Letters. 411, p. 57-63 7 p.

Research output: Contribution to journalArticle

19 Scopus citations
2011

Aldose reductase deficiency protects sugar-induced lens opacification in rats

Reddy, A. B. M., Tammali, R., Mishra, R., Srivastava, S., Srivastava, S. K. & Ramana, K. V., May 30 2011, In : Chemico-Biological Interactions. 191, 1-3, p. 346-350 5 p.

Research output: Contribution to journalArticle

20 Scopus citations
2018

Therapeutic potential of natural antioxidants

Ramana, K. V., Reddy, A. B. M., Ravi Kumar Majeti, N. V. & Singhal, S. S., Jan 1 2018, In : Oxidative medicine and cellular longevity. 2018, 9471051.

Research output: Contribution to journalEditorial

7 Scopus citations
2019

4-Hydroxy-Trans-2-Nonenal in the Regulation of Anti-Oxidative and Pro-Inflammatory Signaling Pathways

Sonowal, H. & Ramana, K. V., Jan 1 2019, In : Oxidative medicine and cellular longevity. 2019, 5937326.

Research output: Contribution to journalReview article

Open Access
2012

A potential therapeutic role for aldose reductase inhibitors in the treatment of endotoxin-related inflammatory diseases

Pandey, S., Srivastava, S. K. & Ramana, K. V., Mar 1 2012, In : Expert Opinion on Investigational Drugs. 21, 3, p. 329-339 11 p.

Research output: Contribution to journalReview article

23 Scopus citations
2018

Aldose reductase inhibitor, fidarestat prevents high-fat diet-induced intestinal polyps in APCmin/+ mice

Saxena, A., Tammali, R., Ramana, K. & Srivastava, S., Jan 1 2018, In : Current Cancer Drug Targets. 18, 9, p. 905-911 7 p.

Research output: Contribution to journalArticle

2 Scopus citations
2016

Regulatory roles of glutathione-S-transferases and 4-hydroxynonenal in stress-mediated signaling and toxicity

Awasthi, Y. C., Ramana, K., Chaudhary, P., Srivastava, S. & Awasthi, S., Sep 15 2016, (Accepted/In press) In : Free Radical Biology and Medicine.

Research output: Contribution to journalArticle

17 Scopus citations
2011

Targeting aldose reductase for the treatment of cancer

Tammali, R., Srivastava, S. K. & Ramana, K. V., Jun 2011, In : Current Cancer Drug Targets. 11, 5, p. 560-571 12 p.

Research output: Contribution to journalReview article

46 Scopus citations

Aldose reductase: New insights for an old enzyme

Ramana, K. V., Apr 1 2011, In : Biomolecular Concepts. 2, 1-2, p. 103-114 12 p.

Research output: Contribution to journalReview article

91 Scopus citations

Aldose reductase inhibition suppresses oxidative stress-induced inflammatory disorders

Srivastava, S. K., Yadav, U. C. S., Reddy, A. B. M., Saxena, A., Tammali, R., Shoeb, M., Ansari, N. H., Bhatnagar, A., Petrash, M. J., Srivastava, S. & Ramana, K. V., May 30 2011, In : Chemico-Biological Interactions. 191, 1-3, p. 330-338 9 p.

Research output: Contribution to journalArticle

101 Scopus citations

Inhibition of aldose reductase prevents endotoxin-induced inflammation by regulating the arachidonic acid pathway in murine macrophages

Shoeb, M., Yadav, U. C. S., Srivastava, S. K. & Ramana, K. V., Nov 1 2011, In : Free Radical Biology and Medicine. 51, 9, p. 1686-1696 11 p.

Research output: Contribution to journalArticle

30 Scopus citations
2019

Aldose reductase regulates hyperglycemia-induced huvec death via SIRT1/AMPK-α1/mTOR pathway

Pal, P., Sonowal, H., Shukla, K., Srivastava, S. K. & Ramana, K. V., 2019, In : Journal of Molecular Endocrinology. 63, 1, p. 11-25 15 p.

Research output: Contribution to journalArticle

4 Scopus citations

Didymin by suppressing NF-κB activation prevents VEGF-induced angiogenesis in vitro and in vivo

Shukla, K., Sonowal, H., Saxena, A. & Ramana, K., Jan 1 2019, (Accepted/In press) In : Vascular Pharmacology.

Research output: Contribution to journalArticle

3 Scopus citations
2011

Aldose reductase deficiency in mice protects from ragweed pollen extract (RWE)-induced allergic asthma

Yadav, U. C. S., Aguilera-Aguirre, L., Boldogh, I., Ramana, K. V. & Srivastava, S. K., Nov 3 2011, In : Respiratory Research. 12, 145.

Research output: Contribution to journalArticle

7 Scopus citations

Inhibition of aldose reductase prevents angiogenesis in vitro and in vivo

Tammali, R., Reddy, A. B. M., Srivastava, S. K. & Ramana, K. V., May 1 2011, In : Angiogenesis. 14, 2, p. 209-221 13 p.

Research output: Contribution to journalArticle

45 Scopus citations
2018

Vialinin A, an Edible Mushroom-Derived p-Terphenyl Antioxidant, Prevents VEGF-Induced Neovascularization in Vitro and in Vivo

Sonowal, H., Shukla, K., Kota, S., Saxena, A. & Ramana, K. V., 2018, In : Oxidative medicine and cellular longevity. 2018, 1052102.

Research output: Contribution to journalArticle

2 Scopus citations
2016
2014

Lipid peroxidation products in human health and disease 2014.

Ramana, K. V., Sanjay, S. & Sharad, S. S., Sep 14 2014, In : Oxidative Medicine and Cellular Longivity.

Research output: Contribution to journalArticle

10 Scopus citations
2011
29 Scopus citations

Amelioration of experimental autoimmune uveoretinitis by aldose reductase inhibition in lewis Rats

Yadav, U. C. S., Shoeb, M., Srivastava, S. K. & Ramana, K. V., Oct 1 2011, In : Investigative Ophthalmology and Visual Science. 52, 11, p. 8033-8041 9 p.

Research output: Contribution to journalArticle

8 Scopus citations
2016

Corrigendum to "Aldose reductase inhibition suppresses oxidative stress-induced inflammatory disorders" [Chem. Biol. Interact. (2011) 330-338]

Srivastava, S., Yadav, U. C. S., Reddy, A. B. M., Mishra, R., Saxena, A., Tammali, R., Shoeb, M., Ansari, N., Bhatnagar, A., Petrash, M. J., Srivastava, S. & Ramana, K., 2016, (Accepted/In press) In : Chemico-Biological Interactions.

Research output: Contribution to journalArticle

2018

Didymin prevents hyperglycemia-induced human umbilical endothelial cells dysfunction and death

Shukla, K., Sonowal, H., Saxena, A. & Ramana, K., Jun 1 2018, In : Biochemical Pharmacology. 152, p. 1-10 10 p.

Research output: Contribution to journalArticle

10 Scopus citations
2017

Aldose reductase inhibitor increases doxorubicin-sensitivity of colon cancer cells and decreases cardiotoxicity

Sonowal, H., Pal, P. B., Wen, J. J., Awasthi, S., Ramana, K. & Srivastava, S., Dec 1 2017, In : Scientific Reports. 7, 1, 3182.

Research output: Contribution to journalArticle

17 Scopus citations
2016

Immune, Inflammatory, and Oxidative Responses in Cardiovascular Complications

Ramana, K. V., Srivastava, S. & Reddy, A. B. M., Jan 1 2016, In : Oxidative medicine and cellular longevity. 2016, 6858402.

Research output: Contribution to journalEditorial

1 Scopus citations
2017

Lipid Peroxidation Products in Human Health and Disease 2016

Ramana, K. V., Srivastava, S. & Singhal, S. S., Jan 1 2017, In : Oxidative medicine and cellular longevity. 2017, 2163285.

Research output: Contribution to journalEditorial

19 Scopus citations

Aldose reductase mediates NLRP3 inflammasome-initiated innate immune response in hyperglycemia-induced thp1 monocytes and male mice

Pal, P. B., Sonowal, H., Shukla, K., Srivastava, S. & Ramana, K., Oct 1 2017, In : Endocrinology. 158, 10, p. 3661-3675 15 p.

Research output: Contribution to journalArticle

10 Scopus citations
2011

Current prospective of aldose reductase inhibition in the therapy of allergic airway inflammation in asthma

Ramana, K. V., Yadav, U. C. S., Calhoun, W. J. & Srivastava, S. K., Jan 1 2011, In : Current molecular medicine. 11, 7, p. 599-608 10 p.

Research output: Contribution to journalReview article

6 Scopus citations
2017
8 Scopus citations
2014

Therapeutic potential of natural pharmacological agents in the treatment of human diseases

Ramana, K. V., Singhal, S. S. & Reddy, A. B., Dec 28 2014, In : BioMed Research International. 2014, 573452.

Research output: Contribution to journalEditorial

9 Scopus citations

Aldose reductase inhibition suppresses azoxymethane-induced colonic premalignant lesions in C57BL/KsJ-db/db mice

Saxena, A., Shoeb, M., Tammali, R., Ramana, K. V. & Srivastava, S. K., Dec 1 2014, In : Cancer Letters. 355, 1, p. 141-147 7 p.

Research output: Contribution to journalArticle

9 Scopus citations
2012

How Does Oxidative Stress Affect Inflammasome Activation?

Mohammad, S. & Ramana, K. V., 2012, In : J Clin Cell Immunol. 3, p. 107

Research output: Contribution to journalArticle

Antidiabetic drug metformin suppresses endotoxin-induced uveitis in rats

Kalariya, N. M., Shoeb, M., Ansari, N. H., Srivastava, S. K. & Ramana, K. V., Jun 1 2012, In : Investigative Ophthalmology and Visual Science. 53, 7, p. 3431-3440 10 p.

Research output: Contribution to journalArticle

30 Scopus citations
2011

Post-translational protein modification by carotenoid cleavage products

Kalariya, N. M., Ramana, K. V., Srivastava, S. K. & van Kuijk, F. J. G. M., Mar 1 2011, In : BioFactors. 37, 2, p. 104-116 13 p.

Research output: Contribution to journalArticle

5 Scopus citations
2019
2011

Aldose reductase: New insights for an old enzyme

Ramana, K. V., 2011, In : Biomol Concepts. 2, p. 103-114

Research output: Contribution to journalArticle

91 Scopus citations

Aldose reductase deficiency protects from autoimmune- and endotoxin-induced uveitis in mice

Yadav, U. C. S., Shoeb, M., Srivastava, S. K. & Ramana, K. V., Oct 1 2011, In : Investigative Ophthalmology and Visual Science. 52, 11, p. 8076-8085 10 p.

Research output: Contribution to journalArticle

19 Scopus citations
2017

Applications of Antioxidants in Ameliorating Drugs and Xenobiotics Toxicity: Mechanistic Approach

Abdel-Daim, M. M., Moustafa, Y. M., Umezawa, M., Ramana, K. & Azzini, E., 2017, In : Oxidative Medicine and Cellular Longevity. 2017, 4565127.

Research output: Contribution to journalEditorial

8 Scopus citations
2011

Preventive effects of ethyl pyruvate on endotoxin-induced uveitis in rats

Kalariya, N. M., Reddy, A. B. M., Ansari, N. H., VanKuijk, F. J. G. M. & Ramana, K. V., Jul 1 2011, In : Investigative Ophthalmology and Visual Science. 52, 8, p. 5144-5152 9 p.

Research output: Contribution to journalArticle

17 Scopus citations

Aldose reductase inhibition suppresses airway inflammation

Yadav, U. C. S., Ramana, K. V. & Srivastava, S. K., May 30 2011, In : Chemico-Biological Interactions. 191, 1-3, p. 339-345 7 p.

Research output: Contribution to journalArticle

19 Scopus citations
2014

Lipid peroxidation products in human health and disease 2014

Ramana, K. V., Srivastava, S. & Singhal, S. S., 2014, In : Oxidative Medicine and Cellular Longevity. 2014, p. 162414 1 p.

Research output: Contribution to journalArticle

10 Scopus citations
2011

Inhibition of aldose reductase prevents colon cancer metastasis

Tammali, R., Reddy, A. B. M., Saxena, A., Rychahou, P. G., Evers, B. M., Qiu, S., Awasthi, S., Ramana, K. V. & Srivastava, S. K., Aug 11 2011, In : Carcinogenesis. 32, 8, p. 1259-1267 9 p.

Research output: Contribution to journalArticle

37 Scopus citations
2017

Aldose Reductase Inhibitor Protects against Hyperglycemic Stress by Activating Nrf2-Dependent Antioxidant Proteins

Shukla, K., Pal, P. B., Sonowal, H., Srivastava, S. K. & Ramana, K. V., 2017, In : Journal of Diabetes Research. 2017, 6785852.

Research output: Contribution to journalArticle

5 Scopus citations
2012

Focus on Molecules: Lutein

Kalariya, N. M., Ramana, K. V. & vanKuijk, F. J. G. M., Sep 1 2012, In : Experimental Eye Research. 102, p. 107-108 2 p.

Research output: Contribution to journalShort survey

6 Scopus citations
2011

Emerging role of antioxidants in the protection of uveitis complications

Yadav, U. C. S., Kalariya, N. M. & Ramana, K. V., Feb 1 2011, In : Current Medicinal Chemistry. 18, 6, p. 931-942 12 p.

Research output: Contribution to journalArticle

37 Scopus citations
2014

4-hydroxynonenal in the pathogenesis and progression of human diseases

Shoeb, M., Ansari, N. H., Srivastava, S. K. & Ramana, K. V., Jan 1 2014, In : Current Medicinal Chemistry. 21, 2, p. 230-237 8 p.

Research output: Contribution to journalArticle

66 Scopus citations
2018

Transcriptional factor modulation by lipid peroxidation-derived aldehydes

Saxena, A., Sonowal, H. & Ramana, K. V., Jan 1 2018, The Molecular Nutrition of Fats. Elsevier, p. 419-431 13 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

2012

What is the role of 4-hydroxynonenal in inflammation?

Ramana, K. V., 2012, In : Biochem AnaBiochem. 1

Research output: Contribution to journalArticle