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  • Steven Widen
2019

Characterization of triniti virus supports its reclassification in the family peribunyaviridae

Lima, J. A., Neto, J. P. N., Castro, K. S., da Rosa, A. P. D. A. T., Tesh, R., Nunes, M. R. T., Popov, V. L., Vasilakis, N., Guzman, H., Widen, S., da Silva, S. P., Medeiros, D. B. D. A., Cardoso, J. F., Martins, L. C., Azevedo, R. D. S. D. S., Vasconcelos, P. F. D. C. & Chiang, J. O., Feb 2019, In : Journal of General Virology. 100, 2, p. 137-144 8 p., 001196.

Research output: Contribution to journalArticle

2 Scopus citations
2016

Differential Responses of Human Fetal Brain Neural Stem Cells to Zika Virus Infection

McGrath, E. L., Rossi, S. L., Gao, J., Widen, S. G., Grant, A. C., Dunn, T. J., Azar, S. R., Roundy, C. M., Xiong, Y., Prusak, D. J., Loucas, B. D., Wood, T., Yu, Y., Fernández-Salas, I., Weaver, S. C., Vasilakis, N. & Wu, P., Jul 27 2016, (Accepted/In press) In : Stem Cell Reports.

Research output: Contribution to journalArticle

53 Scopus citations
2019

Hippocampal stem cells promotes synaptic resistance to the dysfunctional impact of amyloid beta oligomers via secreted exosomes

Micci, M. A., Krishnan, B., Bishop, E., Zhang, W. R., Guptarak, J., Grant, A., Zolochevska, O., Tumurbaatar, B., Franklin, W., Marino, C., Widen, S. G., Luthra, A., Kernie, S. G. & Taglialatela, G., Jun 14 2019, In : Molecular Neurodegeneration. 14, 1, 25.

Research output: Contribution to journalArticle

Open Access
2 Scopus citations
2015

Evolution of Genome Size and Complexity in the Rhabdoviridae

Walker, P. J., Firth, C., Widen, S. G., Blasdell, K. R., Guzman, H., Wood, T. G., Paradkar, P. N., Holmes, E. C., Tesh, R. B. & Vasilakis, N., Jan 1 2015, In : PLoS pathogens. 11, 2, e1004664.

Research output: Contribution to journalArticle

79 Scopus citations
2019

Exploiting the Legacy of the Arbovirus Hunters

Vasilakis, N., Tesh, R. B., Popov, V., Widen, S., Wood, T. G., Forrester, N. L., Gonzalez, J. P., Saluzzo, J. F., Alkhovsky, S., Lam, S. K., Mackenzie, J. S. & Walker, P. J., May 23 2019, In : Viruses. 11, 5

Research output: Contribution to journalReview article

Open Access
1 Scopus citations

Ixodes scapularis salivary gland microRNAs are differentially expressed during Powassan virus transmission

Hermance, M., Widen, S. G., Wood, T. G. & Thangamani, S., Dec 1 2019, In : Scientific reports. 9, 1, 13110.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations
2015

Correction to: Molecular Characterisation of Chikungunya Virus Infections in Trinidad and Comparison of Clinical and Laboratory Features with Dengue and Other Acute Febrile Cases (PLoS Negl, (2015) 9, [12])

Sahadeo, N., Mohammed, H., Allicock, O. M., Auguste, A. J., Widen, S. G., Badal, K., Pulchan, K., Foster, J. E., Weaver, S. C. & Carrington, C. V. F., Dec 11 2015, In : PLoS neglected tropical diseases. 9, 12, e0004305.

Research output: Contribution to journalComment/debate

3 Scopus citations
2014

Koolpinyah and Yata viruses: Two newly recognised ephemeroviruses from tropical regions of Australia and Africa

Blasdell, K. R., Widen, S. G., Diviney, S. M., Firth, C., Wood, T. G., Guzman, H., Holmes, E. C., Tesh, R. B., Vasilakis, N. & Walker, P. J., Jan 1 2014, In : Veterinary Microbiology. 174, 3-4, p. 547-553 7 p.

Research output: Contribution to journalArticle

5 Scopus citations
2020

Ebola virus produces discrete small noncoding RNAs independently of the host MicroRNA pathway which lack RNA interference activity in bat and human cells

Prasad, A., Ronk, A. J., Widen, S. G., Wood, T. G., Basler, C. F. & Bukreyev, A., Mar 1 2020, In : Journal of virology. 94, 6, e01441-19.

Research output: Contribution to journalArticle

2 Scopus citations
2017

Corrigendum to ‘Sinu virus, a novel and divergent orthomyxovirus related to members of the genus Thogotovirus isolated from mosquitoes in Colombia’ [Virology 501 (2017) 166–175] (S0042682216303683)(10.1016/j.virol.2016.11.014)

Contreras-Gutiérrez, M. A., Nunes, M. R. T., Guzman, H., Uribe, S., Suaza Vasco, J. D., Cardoso, J. F., Popov, V. L., Widen, S. G., Wood, T. G., Vasilakis, N. & Tesh, R. B., Mar 1 2017, In : Virology. 503, 1 p.

Research output: Contribution to journalComment/debate

2020

Dianke virus: A new mesonivirus species isolated from mosquitoes in Eastern Senegal

Diagne, M. M., Gaye, A., Ndione, M. H. D., Faye, M., Fall, G., Dieng, I., Widen, S. G., Wood, T. G., Popov, V., Guzman, H., Bâ, Y., Weaver, S. C., Diallo, M., Tesh, R., Faye, O., Vasilakis, N. & Sall, A. A., Jan 2 2020, In : Virus Research. 275, 197802.

Research output: Contribution to journalArticle

1 Scopus citations
2018

Genetic characterization of the patois serogroup (Genus Orthobunyavirus; Family Peribunyaviridae) and evidence that estero real virus is a member of the genus orthonairovirus

Aguilar, P. V., De Souza, W. M., Silvas, J. A., Wood, T., Widen, S., Fumagalli, M. J. & Nunes, M. R. T., Jan 1 2018, In : American Journal of Tropical Medicine and Hygiene. 99, 2, p. 451-457 7 p.

Research output: Contribution to journalArticle

2 Scopus citations
2019

Type II Epithelial-Mesenchymal Transition Upregulates Protein N-Glycosylation to Maintain Proteostasis and Extracellular Matrix Production

Zhang, J., Jamaluddin, M., Zhang, Y., Widen, S. G., Sun, H., Brasier, A. R. & Zhao, Y., Sep 6 2019, In : Journal of Proteome Research. 18, 9, p. 3447-3460 14 p.

Research output: Contribution to journalArticle

2 Scopus citations
2014

Characterization of a novel Negevirus and a novel Bunyavirus isolated from Culex (Culex) declarator mosquitoes in Trinidad

Auguste, A. J., Carrington, C. V. F., Forrester, N. L., Popov, V. L., Guzman, H., Widen, S. G., Wood, T. G., Weaver, S. C. & Tesh, R. B., Feb 1 2014, In : Journal of General Virology. 95, PART 2, p. 481-485 5 p.

Research output: Contribution to journalArticle

50 Scopus citations
2016

Outbreak of Zika Virus Infection, Chiapas State, Mexico, 2015, and First Confirmed Transmission by Aedes aegypti Mosquitoes in the Americas

Guerbois, M., Fernandez-Salas, I., Azar, S. R., Danis-Lozano, R., Alpuche-Aranda, C. M., Leal, G., Garcia-Malo, I. R., Diaz-Gonzalez, E. E., Casas-Martinez, M., Rossi, S. L., Del Río-Galván, S. L., Sanchez-Casas, R. M., Roundy, C. M., Wood, T. G., Widen, S. G., Vasilakis, N. & Weaver, S. C., Nov 1 2016, In : Journal of Infectious Diseases. 214, 9, p. 1349-1356 8 p.

Research output: Contribution to journalArticle

116 Scopus citations
2015

Itaya virus, a novel orthobunyavirus associated with human febrile illness, Peru

Hontz, R. D., Guevara, C., Halsey, E. S., Silvas, J., Santiago, F. W., Widen, S. G., Wood, T. G., Casanova, W., Vasilakis, N., Watts, D. M., Kochel, T. J., Ebihara, H. & Aguilar, P. V., Jan 1 2015, In : Emerging infectious diseases. 21, 5, p. 781-788 8 p.

Research output: Contribution to journalArticle

14 Scopus citations
2020
Open Access
2017

Abundance and distribution of sylvatic dengue virus vectors in three different land cover types in Sarawak, Malaysian Borneo

Young, K. I., Mundis, S., Widen, S. G., Wood, T. G., Tesh, R. B., Cardosa, J., Vasilakis, N., Perera, D. & Hanley, K. A., Aug 31 2017, In : Parasites and Vectors. 10, 1, 406.

Research output: Contribution to journalArticle

8 Scopus citations
2014

Mesoniviruses are mosquito-specific viruses with extensive geographic distribution and host range

Vasilakis, N., Guzman, H., Firth, C., Forrester, N. L., Widen, S. G., Wood, T. G., Rossi, S. L., Ghedin, E., Popov, V., Blasdell, K. R., Walker, P. J. & Tesh, R. B., May 20 2014, In : Virology journal. 11, 1, 97.

Research output: Contribution to journalArticle

38 Scopus citations
2017

Zika virus alters the microRNA expression profile and elicits an RNAi response in Aedes aegypti mosquitoes

Saldaña, M. A., Etebari, K., Hart, C. E., Widen, S. G., Wood, T. G., Thangamani, S., Asgari, S. & Hughes, G. L., Jul 17 2017, In : PLoS neglected tropical diseases. 11, 7, e0005760.

Research output: Contribution to journalArticle

41 Scopus citations
2016
15 Scopus citations
2019

Genotypic and phenotypic characterization of West Nile virus NS5 methyltransferase mutants

Kaiser, J. A., Luo, H., Widen, S. G., Wood, T. G., Huang, C. Y. H., Wang, T. & Barrett, A. D. T., Jan 1 2019, (Accepted/In press) In : Vaccine.

Research output: Contribution to journalArticle

2016

Divergent viruses discovered in arthropods and vertebrates revise the evolutionary history of the Flaviviridae and related viruses

Shi, M., Lin, X. D., Vasilakis, N., Tian, J. H., Li, C. X., Chen, L. J., Eastwood, G., Diao, X. N., Chen, M. H., Chen, X., Qin, X. C., Widen, S. G., Wood, T. G., Tesh, R. B., Xu, J., Holmes, E. C. & Zhang, Y. Z., Jan 1 2016, In : Journal of virology. 90, 2, p. 659-669 11 p.

Research output: Contribution to journalArticle

96 Scopus citations
2014

Malpais spring virus is a new species in the genus vesiculovirus

Vasilakis, N., Widen, S., Travassos Da Rosa, A. P. A., Wood, T., Walker, P. J., Holmes, E. C. & Tesh, R. B., 2014, In : Virology Journal. 10, 69.

Research output: Contribution to journalArticle

2 Scopus citations
2015

Whole transcriptome analysis reveals an 8-oxoguanine DNA glycosylase-1-driven DNA repair-dependent gene expression linked to essential biological processes

Aguilera-Aguirre, L., Hosoki, K., Bacsi, A., Radák, Z., Wood, T. G., Widen, S. G., Sur, S., Ameredes, B. T., Saavedra-Molina, A., Brasier, A. R., Ba, X. & Boldogh, I., Apr 2015, In : Free Radical Biology and Medicine. 81, p. 107-118 12 p.

Research output: Contribution to journalArticle

25 Scopus citations
2017

Sinu virus, a novel and divergent orthomyxovirus related to members of the genus Thogotovirus isolated from mosquitoes in Colombia

Contreras-Gutiérrez, M. A., Nunes, M. R. T., Guzman, H., Uribe, S., Gallego Gómez, J. C., Suaza Vasco, J. D., Cardoso, J. F., Popov, V. L., Widen, S. G., Wood, T. G., Vasilakis, N. & Tesh, R. B., Jan 15 2017, In : Virology. 501, p. 166-175 10 p.

Research output: Contribution to journalArticle

12 Scopus citations
2019

Development of a novel ex vivo nasal epithelial cell model supporting colonization with human nasal microbiota

Charles, D. D., Fisher, J. R., Hoskinson, S. M., Medina-Colorado, A. A., Shen, Y. C., Chaaban, M. R., Widen, S. G., Eaves-Pyles, T. D., Maxwell, C. A., Miller, A. L., Popov, V. L. & Pyles, R. B., 2019, In : Frontiers in Cellular and Infection Microbiology. 9, MAY, 165.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations

Attenuation of zika virus by passage in human HeLa cells

Li, L., Collins, N. D., Widen, S. G., Davis, E. H., Kaiser, J. A., White, M. M., Greenberg, M. B., Barrett, A. D. T., Bourne, N. & Sarathy, V. V., Sep 2019, In : Vaccines. 7, 3, 93.

Research output: Contribution to journalArticle

Open Access
2 Scopus citations
2020

Severe acute respiratory syndrome coronavirus 2 from patient with coronavirus disease, United States

Harcourt, J., Tamin, A., Lu, X., Kamili, S., Sakthivel, S. K., Murray, J., Queen, K., Tao, Y., Paden, C. R., Zhang, J., Li, Y., Uehara, A., Wang, H., Goldsmith, C., Bullock, H. A., Wang, L., Whitaker, B., Lynch, B., Gautam, R., Schindewolf, C. & 14 others, Lokugamage, K. G., Scharton, D., Plante, J. A., Mirchandani, D., Widen, S. G., Narayanan, K., Makino, S., Ksiazek, T. G., Plante, K. S., Weaver, S. C., Lindstrom, S., Tong, S., Menachery, V. D. & Thornburg, N. J., Jun 1 2020, In : Emerging infectious diseases. 26, 6, p. 1266-1273 8 p.

Research output: Contribution to journalArticle

Open Access
15 Scopus citations
2019

Inter- and intra-lineage genetic diversity of wild-type Zika viruses reveals both common and distinctive nucleotide variants and clusters of genomic diversity

Collins, N. D., Widen, S., Li, L., Swetnam, D. M., Shi, P-Y., Tesh, R. B. & Sarathy, V., Jan 1 2019, In : Emerging Microbes and Infections. 8, 1, p. 1126-1138 13 p.

Research output: Contribution to journalArticle

Open Access
2 Scopus citations
2018

Characterization of three new insect-specific flaviviruses: Their relationship to the mosquito-borne flavivirus pathogens

Guzman, H., Contreras-Gutierrez, M. A., Travassos da Rosa, A. P. A., Nunes, M. R. T., Cardoso, J. F., Popov, V. L., Young, K. I., Savit, C., Wood, T. G., Widen, S. G., Watts, D. M., Hanley, K. A., Perera, D., Fish, D., Vasilakis, N. & Tesh, R. B., Jan 1 2018, In : American Journal of Tropical Medicine and Hygiene. 98, 2, p. 410-419 10 p.

Research output: Contribution to journalArticle

14 Scopus citations
2015

Insect-specific viruses detected in laboratory mosquito colonies and their potential implications for experiments evaluating arbovirus vector competence

Bolling, B. G., Vasilakis, N., Guzman, H., Widen, S. G., Wood, T. G., Popov, V. L., Thangamani, S. & Tesh, R. B., Feb 1 2015, In : American Journal of Tropical Medicine and Hygiene. 92, 2, p. 422-428 7 p.

Research output: Contribution to journalArticle

29 Scopus citations
2014

Lineage II of southeast Asian/American DENV-2 is associated with a severe dengue outbreak in the Peruvian Amazon

Williams, M., Mayer, S. V., Johnson, W. L., Chen, R., Volkova, E., Vilcarromero, S., Widen, S. G., Wood, T. G., Suarez-Ognio, L., Long, K. C., Hanley, K. A., Morrison, A. C., Vasilakis, N. & Halsey, E. S., Sep 1 2014, In : American Journal of Tropical Medicine and Hygiene. 91, 3, p. 611-620 10 p.

Research output: Contribution to journalArticle

27 Scopus citations
2019

Japanese encephalitis vaccine-specific envelope protein E138K mutation does not attenuate virulence of West Nile virus

Kaiser, J. A., Luo, H., Widen, S. G., Wood, T. G., Huang, C. Y. H., Wang, T. & Barrett, A. D. T., Dec 1 2019, In : npj Vaccines. 4, 1, 50.

Research output: Contribution to journalArticle

Open Access

Genomic characterisation of Cuiaba and Charleville viruses: arboviruses (family Rhabdoviridae, genus Sripuvirus) infecting reptiles and amphibians

Vasilakis, N., Tesh, R. B., Widen, S., Mirchandani, D. & Walker, P. J., Feb 15 2019, In : Virus Genes. 55, 1, p. 87-94 8 p.

Research output: Contribution to journalArticle

2 Scopus citations
2018

Genome sequence of chiqui virus, a novel reovirus isolated from mosquitoes collected in Colombia

Contreras-Gutiérrez, M. A., Guzman, H., Cardoso, J. F., Popov, V. L., Nunes, M. R. T., Uribe, S., Widen, S. G., Wood, T. G., Vasilakis, N. & Tesh, R. B., Sep 27 2018, In : Microbiology Resource Announcements. 7, 12, e00881-18.

Research output: Contribution to journalArticle

1 Scopus citations
2020

Genes of the cGMP-PKG-Ca2+ signaling pathway are alternatively spliced in cardiomyopathy: Role of RBFOX2

Wan, X., Belanger, K. A., Widen, S. G., Kuyumcu-Martinez, M. N. & Garg, N. J., Mar 1 2020, In : Biochimica et Biophysica Acta - Molecular Basis of Disease. 1866, 3, 165620.

Research output: Contribution to journalArticle

MicroRNA sequencing of rat hippocampus and human biofluids identifies acute, chronic, focal and diffuse traumatic brain injuries

Weisz, H. A., Kennedy, D., Widen, S., Spratt, H., Sell, S. L., Bailey, C., Moore, M., DeWitt, D. S., Prough, D. S., Levin, H., Robertson, C. & Hellmich, H. L., Dec 1 2020, In : Scientific reports. 10, 1, 3341.

Research output: Contribution to journalArticle

Open Access
2015

Ledantevirus: A proposed new genus in the rhabdoviridae has a strong ecological association with bats

Blasdell, K. R., Guzman, H., Widen, S. G., Firth, C., Wood, T. G., Holmes, E. C., Tesh, R. B., Vasilakis, N. & Walker, P. J., Feb 1 2015, In : American Journal of Tropical Medicine and Hygiene. 92, 2, p. 405-410 6 p.

Research output: Contribution to journalArticle

20 Scopus citations
2017

Upregulation of cystathionine-β-synthase in colonic epithelia reprograms metabolism and promotes carcinogenesis

Phillips, CN. M., Zatarain, J. R., Nicholls, M. E., Porter, C., Widen, S., Thanki, K., Johnson, P., Jawad, M. U., Moyer, M. P., Randall, J. W., Hellmich, J. L., Maskey, M., Qiu, S., Wood, T., Druzhyna, N., Szczesny, B., Modis, K., Szabo, C., Chao, C. & Hellmich, M., Nov 1 2017, In : Cancer Research. 77, 21, p. 5741-5754 14 p.

Research output: Contribution to journalArticle

21 Scopus citations
2020

Using next generation sequencing to study the genetic diversity of candidate live attenuated zika vaccines

Collins, N. D., Shan, C., Nunes, B. T. D., Widen, S. G., Shi, P. Y., Barrett, A. D. T. & Sarathy, V. V., Apr 2020, In : Vaccines. 8, 2, 161.

Research output: Contribution to journalArticle

Open Access
2015

Mercadeo virus: A novel mosquito-specific flavivirus from Panama

Carrera, J. P., Guzman, H., Beltrán, D., Díaz, Y., López-Vergès, S., Torres-Cosme, R., Popov, V., Widen, S., Wood, T., Weaver, S., Cáceres-Carrera, L., Vasilakis, N. & Tesh, R. B., Nov 4 2015, In : American Journal of Tropical Medicine and Hygiene. 93, 5, p. 1014-1019 6 p.

Research output: Contribution to journalArticle

16 Scopus citations
2018

Structural and Nonstructural Genes Contribute to the Genetic Diversity of RNA Viruses

Collins, N. D., Beck, A. S., Widen, S. G., Wood, T. G., Higgs, S. & Barrett, A. D. T., Oct 30 2018, In : mBio. 9, 5, e01871-18.

Research output: Contribution to journalArticle

11 Scopus citations

Regulons and protein–protein interactions of PRD-containing Bacillus anthracis virulence regulators reveal overlapping but distinct functions

Raynor, M. J., Roh, J. H., Widen, S., Wood, T. & Koehler, T. M., Jul 1 2018, In : Molecular Microbiology. 109, 1, p. 1-22 22 p.

Research output: Contribution to journalArticle

3 Scopus citations
2015

Analysis of the TGFβ-induced program in primary airway epithelial cells shows essential role of NF-ΚB/RelA signaling network in type II epithelial mesenchymal transition

Tian, B., Li, X., Kalita, M., Widen, S., Yang, J., Bhavnani, S., Dang, B., Kudlicki, A., Sinha, M., Kong, F., Wood, T., Luxon, B. A. & Brasier, A. R., Jul 18 2015, In : BMC Genomics. 16, 1, 529.

Research output: Contribution to journalArticle

39 Scopus citations

Molecular Characterisation of Chikungunya Virus Infections in Trinidad and Comparison of Clinical and Laboratory Features with Dengue and Other Acute Febrile Cases

Sahadeo, N., Mohammed, H., Allicock, O. M., Auguste, A. J., Widen, S. G., Badal, K., Pulchan, K., Foster, J. E., Weaver, S. C. & Carrington, C. V. F., Nov 18 2015, In : PLoS neglected tropical diseases. 9, 11, e0004199.

Research output: Contribution to journalArticle

29 Scopus citations
2011
36 Scopus citations
2017

Almendravirus: A proposed new genus of rhabdoviruses isolated from mosquitoes in tropical regions of the Americas

Contreras, M. A., Eastwood, G., Guzman, H., Popov, V., Savit, C., Uribe, S., Kramer, L. D., Wood, T. G., Widen, S. G., Fish, D., Tesh, R. B., Vasilakis, N. & Walker, P. J., Jan 2017, In : American Journal of Tropical Medicine and Hygiene. 96, 1, p. 100-109 10 p.

Research output: Contribution to journalArticle

12 Scopus citations

Transcriptional immunoprofiling at the Tick-Virus-Host interface during early stages of tick-borne encephalitis virus transmission

Thangamani, S., Hermance, M. E., Santos, R. I., Slovak, M., Heinze, D., Widen, S. G. & Kazimirova, M., Dec 1 2017, In : Frontiers in Cellular and Infection Microbiology. 7, DEC, 494.

Research output: Contribution to journalArticle

7 Scopus citations
2018

Comparative Transcriptomics in Ebola Makona-Infected Ferrets, Nonhuman Primates, and Humans

Cross, R., Speranza, E., Borisevich, V., Widen, S., Wood, T., Shim, R. S., Adams, R. D., Gerhardt, D. M., Bennett, R. S., Honko, A. N., Johnson, J. C., Hensley, L. E., Geisbert, T. & Connor, J. H., Nov 22 2018, In : The Journal of infectious diseases. 218, 5, p. S486-S495

Research output: Contribution to journalArticle

6 Scopus citations