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  • Jian Sha
2012
11 Scopus citations
2019

T6SS and ExoA of flesh-eating Aeromonas hydrophila in peritonitis and necrotizing fasciitis during mono- And polymicrobial infections

Fernández-Bravo, A., Kilgore, P. B., Andersson, J. A., Blears, E., Figueras, M. J., Hasan, N. A., Colwell, R. R., Sha, J. & Chopra, A. K., Nov 26 2019, In : Proceedings of the National Academy of Sciences of the United States of America. 116, 48, p. 24084-24092 9 p.

Research output: Contribution to journalArticle

3 Scopus citations
2014

Functional genomic characterization of virulence factors from necrotizing fasciitis-causing strains of Aeromonas hydrophila

Grim, C. J., Kozlova, E. V., Ponnusamy, D., Fitts, E. C., Sha, J., Kirtley, M. L., van Lier, C. J., Tiner, B. L., Erova, T. E., Joseph, S. J., Read, T. D., Shak, J. R., Joseph, S. W., Singletary, E., Felland, T., Baze, W. B., Horneman, A. J. & Chopra, A. K., 2014, In : Applied and Environmental Microbiology. 80, 14, p. 4162-4183 22 p.

Research output: Contribution to journalArticle

32 Scopus citations
2011

Cethromycin-mediated protection against the plague pathogen Yersinia pestis in a rat model of infection and comparison with levofloxacin

Rosenzweig, J. A., Brackman, S. M., Kirtley, M. L., Sha, J., Erova, T. E., Yeager, L. A., Peterson, J. W., Xu, Z. Q. & Chopra, A. K., Nov 2011, In : Antimicrobial agents and chemotherapy. 55, 11, p. 5034-5042 9 p.

Research output: Contribution to journalArticle

14 Scopus citations

Quorum sensing and c-di-GMP-dependent alterations in gene transcripts and virulence-associated phenotypes in a clinical isolate of Aeromonas hydrophila

Kozlova, E. V., Khajanchi, B. K., Sha, J. & Chopra, A. K., May 2011, In : Microbial Pathogenesis. 50, 5, p. 213-223 11 p.

Research output: Contribution to journalArticle

25 Scopus citations
2015

Intramuscular immunization of mice with a live-Attenuated triple mutant of yersinia pestis co92 induces robust humoral and cell-mediated immunity to completely protect animals against pneumonic plague

Tiner, B. L., Sha, J., Ponnusamy, D., Baze, W. B., Fitts, E. C., Popov, V. L., Van Lier, C. J., Erova, T. E. & Chopra, A. K., Dec 2015, In : Clinical and Vaccine Immunology. 22, 12, p. 1255-1268 14 p.

Research output: Contribution to journalArticle

8 Scopus citations
2018

Combating multidrug-resistant pathogens with host-directed nonantibiotic therapeutics

Andersson, J. A., Sha, J., Kirtley, M. L., Reyes, E., Fitts, E. C., Dann, S. M. & Chopra, A. K., Jan 2018, In : Antimicrobial agents and chemotherapy. 62, 1, e01943.

Research output: Contribution to journalArticle

7 Scopus citations
2020

New host-directed therapeutics for the treatment of Clostridioides difficile infection

Andersson, J. A., Peniche, A. G., Galindo, C. L., Boonma, P., Sha, J., Luna, R. A., Savidge, T. C., Chopra, A. K. & Dann, S. M., Mar 1 2020, In : mBio. 11, 2, e00053-20.

Research output: Contribution to journalArticle

Open Access
2019

A prokaryotic-eukaryotic hybrid viral vector for delivery of large cargos of genes and proteins into human cells

Zhu, J., Tao, P., Mahalingam, M., Sha, J., Kilgore, P., Chopra, A. K. & Rao, V., Aug 21 2019, In : Science Advances. 5, 8, eaax0064.

Research output: Contribution to journalArticle

Open Access
2 Scopus citations
2012

Actin cross-linking domain of Aeromonas hydrophila repeat in toxin A (RtxA) induces host cell rounding and apoptosis

Suarez, G., Khajanchi, B. K., Sierra, J. C., Erova, T. E., Sha, J. & Chopra, A. K., Sep 15 2012, In : Gene. 506, 2, p. 369-376 8 p.

Research output: Contribution to journalArticle

22 Scopus citations
2011

Progress on plague vaccine development

Rosenzweig, J. A., Jejelowo, O., Sha, J., Erova, T. E., Brackman, S. M., Kirtley, M. L., Van Lier, C. J. & Chopra, A. K., Jul 1 2011, In : Applied Microbiology and Biotechnology. 91, 2, p. 265-286 22 p.

Research output: Contribution to journalReview article

28 Scopus citations
2015

Combinational deletion of three membrane protein-encoding genes highly attenuates Yersinia pestis while retaining immunogenicity in a mouse model of pneumonic plague

Tiner, B. L., Sha, J., Kirtley, M. L., Erova, T. E., Popov, V. L., Baze, W. B., van Lier, C. J., Ponnusamy, D., Andersson, J. A., Motin, V. L., Chauhan, S. & Chopra, A. K., Jan 1 2015, In : Infection and immunity. 83, 4, p. 1318-1338 21 p.

Research output: Contribution to journalArticle

12 Scopus citations
5 Scopus citations
2018

A bacteriophage T4 nanoparticle-based dual vaccine against anthrax and plague

Tao, P., Mahalingam, M., Zhu, J., Moayeri, M., Sha, J., Lawrence, W. S., Leppla, S. H., Chopra, A. K. & Rao, V. B., Sep 1 2018, In : mBio. 9, 5, e01926-18.

Research output: Contribution to journalArticle

12 Scopus citations
2014

Deletion of braun lipoprotein and plasminogen-activating protease-encoding genes attenuates Yersinia pestis in mouse models of bubonic and pneumonic plague

Van Lier, C. J., Sha, J., Kirtley, M. L., Cao, A., Tiner, B. L., Erova, T. E., Cong, Y., Kozlova, E. V., Popov, V. L., Baze, W. B. & Chopra, A. K., 2014, In : Infection and immunity. 82, 6, p. 2485-2503 19 p.

Research output: Contribution to journalArticle

19 Scopus citations
2011

Characterization of an F1 deletion mutant of Yersinia pestis CO92, pathogenic role of F1 antigen in bubonic and pneumonic plague, and evaluation of sensitivity and specificity of F1 antigen capture-based dipsticks

Sha, J., Endsley, J. J., Kirtley, M. L., Foltz, S. M., Huante, M. B., Erova, T. E., Kozlova, E. V., Popov, V. L., Yeager, L. A., Zudina, I. V., Motin, V. L., Peterson, J. W., DeBord, K. L. & Chopra, A. K., May 2011, In : Journal of Clinical Microbiology. 49, 5, p. 1708-1715 8 p.

Research output: Contribution to journalArticle

24 Scopus citations
2015

High-throughput, signature-tagged mutagenic approach to identify novel virulence factors of Yersinia pestis CO92 in a mouse model of infection

Ponnusamy, D., Fitts, E. C., Sha, J., Erova, T. E., Kozlova, E. V., Kirtley, M. L., Tiner, B. L., Andersson, J. A. & Chopra, A. K., 2015, In : Infection and immunity. 83, 5, p. 2065-2081 17 p.

Research output: Contribution to journalArticle

10 Scopus citations
2012

The two-component QseBC signalling system regulates in vitro and in vivo virulence of Aeromonas hydrophila

Khajanchi, B. K., Kozlova, E. V., Sha, J., Popov, V. L. & Chopra, A. K., Jan 2012, In : Microbiology. 158, 1, p. 259-271 13 p.

Research output: Contribution to journalArticle

43 Scopus citations