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  • Alexander Bukreyev
2020

Annexin a2 depletion exacerbates the intracerebral microhemorrhage induced by acute rickettsia and ebola virus infections

Su, Z., Chang, Q., Drelich, A., Shelite, T., Judy, B., Liu, Y., Xiao, J., Zhou, C., He, X., Jin, Y., Saito, T., Tang, S., Soong, L., Wakamiya, M., Fang, X., Bukreyev, A., Ksiazek, T., Russell, W. K. & Gong, B., Jul 2020, In : PLoS neglected tropical diseases. 14, 7, p. 1-30 30 p., e0007960.

Research output: Contribution to journalArticle

Open Access
2018

Staufen1 interacts with multiple components of the ebola virus ribonucleoprotein and enhances viral RNA synthesis

Fang, J., Pietzsch, C., Ramanathan, P., Santos, R. I., Ilinykh, P. A., Garcia-Blanco, M. A., Bukreyev, A. & Bradrick, S. S., Sep 1 2018, In : mBio. 9, 5, e01771-18.

Research output: Contribution to journalArticle

4 Scopus citations

Systematic Analysis of Monoclonal Antibodies against Ebola Virus GP Defines Features that Contribute to Protection

the Viral Hemorrhagic Fever Immunotherapeutic Consortium, Aug 9 2018, In : Cell. 174, 4, p. 938-952.e13

Research output: Contribution to journalArticle

61 Scopus citations

Antibody-Dependent Enhancement of Ebola Virus Infection by Human Antibodies Isolated from Survivors

Kuzmina, N. A., Younan, P., Gilchuk, P., Santos, R. I., Flyak, A. I., Ilinykh, P. A., Huang, K., Lubaki, N. M., Ramanathan, P., Crowe, J. E. & Bukreyev, A., Aug 14 2018, In : Cell Reports. 24, 7, p. 1802-1815.e5

Research output: Contribution to journalArticle

17 Scopus citations
2012

The secreted g protein of human respiratory syncytial virus antagonizes antibody-mediated restriction of replication involving macrophages and complement

Bukreyev, A., Yang, L. & Collins, P. L., Oct 2012, In : Journal of virology. 86, 19, p. 10880-10884 5 p.

Research output: Contribution to journalArticle

24 Scopus citations
2018

Corrigendum: Ebola VP40 in exosomes can cause immune cell dysfunction [Front. Microbiol., 7, (2016), (1765)] doi: 10.3389/fmicb.2016.01765

Pleet, M. L., Mathiesen, A., DeMarino, C., Akpamagbo, Y. A., Barclay, R. A., Schwab, A., Iordanskiy, S., Sampey, G. C., Lepene, B., Ilinykh, P. A., Bukreyev, A., Nekhai, S., Aman, M. J. & Kashanchi, F., Apr 17 2018, In : Frontiers in Microbiology. 9, APR, 692.

Research output: Contribution to journalComment/debate

2020

Species-Specific Evolution of Ebola Virus during Replication in Human and Bat Cells

Whitfield, Z. J., Prasad, A. N., Ronk, A. J., Kuzmin, I. V., Ilinykh, P. A., Andino, R. & Bukreyev, A., Aug 18 2020, In : Cell Reports. 32, 7, 108028.

Research output: Contribution to journalArticle

Open Access
2018

Phosphorylated VP30 of marburg virus is a repressor of transcription

Tigabu, B., Ramanathan, P., Ivanov, A., Lin, X., Ilinykh, P. A., Parry, C. S., Freiberg, A. N., Nekhai, S. & Bukreyev, A., Nov 1 2018, In : Journal of virology. 92, 21, e00426.

Research output: Contribution to journalArticle

6 Scopus citations
2017

Implementation of objective PASC-derived taxon demarcation criteria for official classification of filoviruses

Bào, Y., Amarasinghe, G. K., Basler, C. F., Bavari, S., Bukreyev, A., Chandran, K., Dolnik, O., Dye, J. M., Ebihara, H., Formenty, P., Hewson, R., Kobinger, G. P., Leroy, E. M., Mühlberger, E., Netesov, S. V., Patterson, J. L., Paweska, J. T., Smither, S. J., Takada, A., Towner, J. S. & 3 others, Volchkov, V. E., Wahl-Jensen, V. & Kuhn, J. H., May 11 2017, In : Viruses. 9, 5, 106.

Research output: Contribution to journalLetter

9 Scopus citations
2014

Virus nomenclature below the species level: A standardized nomenclature for filovirus strains and variants rescued from cDNA

Kuhn, J. H., Bào, Y., Bavari, S., Becker, S., Bradfute, S., Brauburger, K., Rodney Brister, J., Bukreyev, A. A., Caì, Y., Chandran, K., Davey, R. A., Dolnik, O., Dye, J. M., Enterlein, S., Gonzalez, J. P., Formenty, P., Freiberg, A. N., Hensley, L. E., Hoenen, T., Honko, A. N. & 32 others, Ignatyev, G. M., Jahrling, P. B., Johnson, K. M., Klenk, H. D., Kobinger, G., Lackemeyer, M. G., Leroy, E. M., Lever, M. S., Mühlberger, E., Netesov, S. V., Olinger, G. G., Palacios, G., Patterson, J. L., Paweska, J. T., Pitt, L., Radoshitzky, S. R., Ryabchikova, E. I., Saphire, E. O., Shestopalov, A. M., Smither, S. J., Sullivan, N. J., Swanepoel, R., Takada, A., Towner, J. S., van der Groen, G., Volchkov, V. E., Volchkova, V. A., Wahl-Jensen, V., Warren, T. K., Warfield, K. L., Weidmann, M. & Nichol, S. T., May 2014, In : Archives of virology. 159, 5, p. 1229-1237 9 p.

Research output: Contribution to journalArticle

52 Scopus citations
2019

Targeting the Non-catalytic RVxF Site of Protein Phosphatase-1 With Small Molecules for Ebola Virus Inhibition

Lin, X., Ammosova, T., Choy, M. S., Pietzsch, C. A., Ivanov, A., Ahmad, A., Saygideğer, Y., Kumari, N., Kovalskyy, D., Üren, A., Peti, W., Bukreyev, A. & Nekhai, S., Sep 13 2019, In : Frontiers in Microbiology. 10, 2145.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations

ICTV virus taxonomy profile: Filoviridae

ICTV Report Consortium, Jun 2019, In : Journal of General Virology. 100, 6, p. 911-912 2 p.

Research output: Contribution to journalArticle

9 Scopus citations
2017

Topoisomerase II inhibitors induce DNA damage-dependent interferon responses circumventing ebola virus immune evasion

Luthra, P., Aguirre, S., Yen, B. C., Pietzsch, C. A., Sanchez-Aparicio, M. T., Tigabu, B., Morlock, L. K., García-Sastre, A., Leung, D. W., Williams, N. S., Fernandez-Sesma, A., Bukreyev, A. & Basler, C. F., Mar 1 2017, In : mBio. 8, 2, e00368-17.

Research output: Contribution to journalArticle

33 Scopus citations
2019

Can Ebola Virus Vaccines Have Universal Immune Correlates of protection?

Meyer, M., Malherbe, D. C. & Bukreyev, A., Jan 2019, In : Trends in Microbiology. 27, 1, p. 8-16 9 p.

Research output: Contribution to journalReview article

6 Scopus citations
2018

Broadly neutralizing antibodies from human survivors target a conserved site in the ebola virus glycoprotein hr2-mper region

Flyak, A. I., Kuzmina, N., Murin, C. D., Bryan, C., Davidson, E., Gilchuk, P., Gulka, C. P., Ilinykh, P. A., Shen, X., Huang, K., Ramanathan, P., Turner, H., Fusco, M. L., Lampley, R., Kose, N., King, H., Sapparapu, G., Doranz, B. J., Ksiazek, T. G., Wright, D. W. & 4 others, Saphire, E. O., Ward, A. B., Bukreyev, A. & Crowe, J. E., Jun 1 2018, In : Nature Microbiology. 3, 6, p. 670-677 8 p.

Research output: Contribution to journalArticle

26 Scopus citations
2017

Innate immune responses of bat and human cells to filoviruses: Commonalities and distinctions

Kuzmin, I. V., Schwarz, T. M., Ilinykh, P. A., Jordan, I., Ksiazek, T. G., Sachidanandam, R., Basler, C. F. & Bukreyev, A., Apr 1 2017, In : Journal of virology. 91, 8, e02471-16.

Research output: Contribution to journalArticle

23 Scopus citations
2014

A comprehensive proteomic view of responses of A549 type II alveolar epithelial cells to human respiratory syncytial virus infection

Dave, K. A., Norris, E. L., Bukreyev, A. A., Headlam, M. J., Buchholz, U. J., Singh, T., Collins, P. L. & Gorman, J. J., Dec 1 2014, In : Molecular and Cellular Proteomics. 13, 12, p. 3250-3269 20 p.

Research output: Contribution to journalArticle

22 Scopus citations

Filovirus refseq entries: Evaluation and selection of filovirus type variants, Type sequences, And names

Kuhn, J. H., Andersen, K. G., Bào, Y., Bavari, S., Becker, S., Bennett, R. S., Bergman, N. H., Blinkova, O., Bradfute, S., Rodney Brister, J., Bukreyev, A., Chandran, K., Chepurnov, A. A., Davey, R. A., Dietzgen, R. G., Doggett, N. A., Dolnik, O., Dye, J. M., Enterlein, S., Fenimore, P. W. & 56 others, Formenty, P., Freiberg, A. N., Garry, R. F., Garza, N. L., Gire, S. K., Gonzalez, J. P., Griffiths, A., Happi, C. T., Hensley, L. E., Herbert, A. S., Hevey, M. C., Hoenen, T., Honko, A. N., Ignatyev, G. M., Jahrling, P. B., Johnson, J. C., Johnson, K. M., Kindrachuk, J., Klenk, H. D., Kobinger, G., Kochel, T. J., Lackemeyer, M. G., Lackner, D. F., Leroy, E. M., Lever, M. S., Mühlberger, E., Netesov, S. V., Olinger, G. G., Omilabu, S. A., Palacios, G., Panchal, R. G., Park, D. J., Patterson, J. L., Paweska, J. T., Peters, C. J., Pettitt, J., Pitt, L., Radoshitzky, S. R., Ryabchikova, E. I., Saphire, E. O., Sabeti, P. C., Sealfon, R., Shestopalov, A. M., Smither, S. J., Sullivan, N. J., Swanepoel, R., Takada, A., Towner, J. S., Van Der Groen, G., Volchkov, V. E., Volchkova, V. A., Wahl-Jensen, V., Warren, T. K., Warfield, K. L., Weidmann, M. & Nichol, S. T., 2014, In : Viruses. 6, 9, p. 3663-3682 20 p.

Research output: Contribution to journalLetter

40 Scopus citations
2017

Possibility and challenges of conversion of current virus species names to Linnaean binomials

Postler, T. S., Clawson, A. N., Amarasinghe, G. K., Basler, C. F., Bavari, S., Benko, M., Blasdell, K. R., Briese, T., Buchmeier, M. J., Bukreyev, A., Calisher, C. H., Chandran, K., Charrel, R., Clegg, C. S., Collins, P. L., De La Torre, J. C., DeRisi, J. L., Dietzgen, R. G., Dolnik, O., Dürrwald, R. & 52 others, Dye, J. M., Easton, A. J., Emonet, S., Formenty, P., Fouchier, R. A. M., Ghedin, E., Gonzalez, J. P., Harrach, B., Hewson, R., Horie, M., Jiāng, D., Kobinger, G., Kondo, H., Kropinski, A. M., Krupovic, M., Kurath, G., Lamb, R. A., Leroy, E. M., Lukashevich, I. S., Maisner, A., Mushegian, A. R., Netesov, S. V., Nowotny, N., Patterson, J. L., Payne, S. L., Paweska, J. T., Peters, C. J., Radoshitzky, S. R., Rima, B. K., Romanowski, V., Rubbenstroth, D., Sabanadzovic, S., Sanfaçon, H., Salvato, M. S., Schwemmle, M., Smither, S. J., Stenglein, M. D., Stone, D. M., Takada, A., Tesh, R. B., Tomonaga, K., Tordo, N., Towner, J. S., Vasilakis, N., Volchkov, V. E., Wahl-Jensen, V., Walker, P. J., Wang, L. F., Varsani, A., Whitfield, A. E., Murilo Zerbini, F. & Kuhn, J. H., May 1 2017, In : Systematic Biology. 66, 3, p. 463-473 11 p.

Research output: Contribution to journalArticle

10 Scopus citations
2018

Multifunctional Pan-ebolavirus Antibody Recognizes a Site of Broad Vulnerability on the Ebolavirus Glycoprotein

Gilchuk, P., Kuzmina, N., Ilinykh, P. A., Huang, K., Gunn, B. M., Bryan, A., Davidson, E., Doranz, B. J., Turner, H. L., Fusco, M. L., Bramble, M. S., Hoff, N. A., Binshtein, E., Kose, N., Flyak, A. I., Flinko, R., Orlandi, C., Carnahan, R., Parrish, E. H., Sevy, A. M. & 12 others, Bombardi, R. G., Singh, P. K., Mukadi, P., Muyembe-Tamfum, J. J., Ohi, M. D., Saphire, E. O., Lewis, G. K., Alter, G., Ward, A. B., Rimoin, A. W., Bukreyev, A. & Crowe, J. E., Aug 21 2018, In : Immunity. 49, 2, p. 363-374.e10

Research output: Contribution to journalArticle

19 Scopus citations
2014

A BSL-4 high-throughput screen identifies sulfonamide inhibitors of Nipah virus

Tigabu, B., Rasmussen, L., White, E. L., Tower, N., Saeed, M., Bukreyev, A., Rockx, B., Leduc, J. W. & Noah, J. W., Apr 1 2014, In : Assay and Drug Development Technologies. 12, 3, p. 155-161 7 p.

Research output: Contribution to journalArticle

11 Scopus citations
2017

Ebola virus binding to Tim-1 on T lymphocytes induces a cytokine storm

Younan, P., Iampietro, M., Nishida, A., Ramanathan, P., Santos, R. I., Dutta, M., Lubaki, N. M., Koup, R. A., Katze, M. G. & Bukreyev, A., Sep 1 2017, In : mBio. 8, 5, e00845-17.

Research output: Contribution to journalArticle

34 Scopus citations
2014

Discussions and decisions of the 2012-2014 International Committee on Taxonomy of Viruses (ICTV) Filoviridae Study Group, January 2012-June 2013

Bukreyev, A. A., Chandran, K., Dolnik, O., Dye, J. M., Ebihara, H., Leroy, E. M., Mühlberger, E., Netesov, S. V., Patterson, J. L., Paweska, J. T., Saphire, E. O., Smither, S. J., Takada, A., Towner, J. S., Volchkov, V. E., Warren, T. K. & Kuhn, J. H., Apr 2014, In : Archives of virology. 159, 4, p. 821-830 10 p.

Research output: Contribution to journalArticle

63 Scopus citations
2018

The Marburgvirus-Neutralizing Human Monoclonal Antibody MR191 Targets a Conserved Site to Block Virus Receptor Binding

King, L. B., Fusco, M. L., Flyak, A. I., Ilinykh, P. A., Huang, K., Gunn, B., Kirchdoerfer, R. N., Hastie, K. M., Sangha, A. K., Meiler, J., Alter, G., Bukreyev, A., Crowe, J. E. & Saphire, E. O., Jan 10 2018, In : Cell Host and Microbe. 23, 1, p. 101-109.e4

Research output: Contribution to journalArticle

11 Scopus citations
2019

Ebola virus-mediated T-lymphocyte depletion is the result of an abortive infection

Younan, P., Santos, R. I., Ramanathan, P., Iampietro, M., Nishida, A., Dutta, M., Ammosova, T., Meyer, M., Katze, M. G., Popov, V. L., Nekhai, S. & Bukreyev, A., 2019, In : PLoS pathogens. 15, 10, e1008068.

Research output: Contribution to journalArticle

Open Access
3 Scopus citations

Taxonomy of the order Mononegavirales: update 2019

Amarasinghe, G. K., Ayllón, M. A., Bào, Y., Basler, C. F., Bavari, S., Blasdell, K. R., Briese, T., Brown, P. A., Bukreyev, A., Balkema-Buschmann, A., Buchholz, U. J., Chabi-Jesus, C., Chandran, K., Chiapponi, C., Crozier, I., de Swart, R. L., Dietzgen, R. G., Dolnik, O., Drexler, J. F., Dürrwald, R. & 64 others, Dundon, W. G., Duprex, W. P., Dye, J. M., Easton, A. J., Fooks, A. R., Formenty, P. B. H., Fouchier, R. A. M., Freitas-Astúa, J., Griffiths, A., Hewson, R., Horie, M., Hyndman, T. H., Jiāng, D., Kitajima, E. W., Kobinger, G. P., Kondō, H., Kurath, G., Kuzmin, I. V., Lamb, R. A., Lavazza, A., Lee, B., Lelli, D., Leroy, E. M., Lǐ, J., Maes, P., Marzano, S. Y. L., Moreno, A., Mühlberger, E., Netesov, S. V., Nowotny, N., Nylund, A., Økland, A. L., Palacios, G., Pályi, B., Pawęska, J. T., Payne, S. L., Prosperi, A., Ramos-González, P. L., Rima, B. K., Rota, P., Rubbenstroth, D., Shī, M., Simmonds, P., Smither, S. J., Sozzi, E., Spann, K., Stenglein, M. D., Stone, D. M., Takada, A., Tesh, R. B., Tomonaga, K., Tordo, N., Towner, J. S., van den Hoogen, B., Vasilakis, N., Wahl, V., Walker, P. J., Wang, L. F., Whitfield, A. E., Williams, J. V., Zerbini, F. M., Zhāng, T., Zhang, Y. Z. & Kuhn, J. H., Jul 1 2019, In : Archives of virology. 164, 7, p. 1967-1980 14 p.

Research output: Contribution to journalArticle

Open Access
51 Scopus citations
2018

Antibody Repertoires to the Same Ebola Vaccine Antigen Are Differentially Affected by Vaccine Vectors

Meyer, M., Yoshida, A., Ramanathan, P., Saphire, E. O., Collins, P. L., Crowe, J. E., Samal, S. & Bukreyev, A., Aug 14 2018, In : Cell Reports. 24, 7, p. 1816-1829 14 p.

Research output: Contribution to journalArticle

2 Scopus citations
2020

Small Molecule Compounds That Inhibit Antioxidant Response Gene Expression in an Inducer-Dependent Manner

Edwards, M. R., Liu, G., De, S., Sourimant, J., Pietzsch, C., Johnson, B., Amarasinghe, G. K., Leung, D. W., Bukreyev, A., Plemper, R. K., Aron, Z., Bowlin, T. L., Moir, D. T. & Basler, C. F., Mar 13 2020, In : ACS Infectious Diseases. 6, 3, p. 489-502 14 p.

Research output: Contribution to journalArticle

2018

Taxonomy of the order Mononegavirales: update 2018

Amarasinghe, G. K., Aréchiga Ceballos, N. G., Banyard, A. C., Basler, C. F., Bavari, S., Bennett, A. J., Blasdell, K. R., Briese, T., Bukreyev, A., Caì, Y., Calisher, C. H., Campos Lawson, C., Chandran, K., Chapman, C. A., Chiu, C. Y., Choi, K. S., Collins, P. L., Dietzgen, R. G., Dolja, V. V., Dolnik, O. & 71 others, Domier, L. L., Dürrwald, R., Dye, J. M., Easton, A. J., Ebihara, H., Echevarría, J. E., Fooks, A. R., Formenty, P. B. H., Fouchier, R. A. M., Freuling, C. M., Ghedin, E., Goldberg, T. L., Hewson, R., Horie, M., Hyndman, T. H., Jiāng, D., Kityo, R., Kobinger, G. P., Kondō, H., Koonin, E. V., Krupovic, M., Kurath, G., Lamb, R. A., Lee, B., Leroy, E. M., Maes, P., Maisner, A., Marston, D. A., Mor, S. K., Müller, T., Mühlberger, E., Ramírez, V. M. N., Netesov, S. V., Ng, T. F. F., Nowotny, N., Palacios, G., Patterson, J. L., Pawęska, J. T., Payne, S. L., Prieto, K., Rima, B. K., Rota, P., Rubbenstroth, D., Schwemmle, M., Siddell, S., Smither, S. J., Song, Q., Song, T., Stenglein, M. D., Stone, D. M., Takada, A., Tesh, R. B., Thomazelli, L. M., Tomonaga, K., Tordo, N., Towner, J. S., Vasilakis, N., Vázquez-Morón, S., Verdugo, C., Volchkov, V. E., Wahl, V., Walker, P. J., Wang, D., Wang, L. F., Wellehan, J. F. X., Wiley, M. R., Whitfield, A. E., Wolf, Y. I., Yè, G., Zhāng, Y. Z. & Kuhn, J. H., Aug 1 2018, In : Archives of virology. 163, 8, p. 2283-2294 12 p.

Research output: Contribution to journalArticle

82 Scopus citations

Disabling of lymphocyte immune response by Ebola virus

Younan, P., Iampietro, M. & Bukreyev, A., Apr 2018, In : PLoS pathogens. 14, 4, e1006932.

Research output: Contribution to journalArticle

11 Scopus citations
2012

The human respiratory syncytial virus nonstructural protein 1 regulates type I and type II interferon pathways

Hastie, M. L., Headlam, M. J., Patel, N. B., Bukreyev, A. A., Buchholz, U. J., Dave, K. A., Norris, E. L., Wright, C. L., Spann, K. M., Collins, P. L. & Gorman, J. J., May 2012, In : Molecular and Cellular Proteomics. 11, 5, p. 108-127 20 p.

Research output: Contribution to journalArticle

38 Scopus citations
2017

Taxonomy of the order Mononegavirales: update 2017

Amarasinghe, G. K., Bào, Y., Basler, C. F., Bavari, S., Beer, M., Bejerman, N., Blasdell, K. R., Bochnowski, A., Briese, T., Bukreyev, A., Calisher, C. H., Chandran, K., Collins, P. L., Dietzgen, R. G., Dolnik, O., Dürrwald, R., Dye, J. M., Easton, A. J., Ebihara, H., Fang, Q. & 53 others, Formenty, P., Fouchier, R. A. M., Ghedin, E., Harding, R. M., Hewson, R., Higgins, C. M., Hong, J., Horie, M., James, A. P., Jiāng, D., Kobinger, G. P., Kondo, H., Kurath, G., Lamb, R. A., Lee, B., Leroy, E. M., Li, M., Maisner, A., Mühlberger, E., Netesov, S. V., Nowotny, N., Patterson, J. L., Payne, S. L., Paweska, J. T., Pearson, M. N., Randall, R. E., Revill, P. A., Rima, B. K., Rota, P., Rubbenstroth, D., Schwemmle, M., Smither, S. J., Song, Q., Stone, D. M., Takada, A., Terregino, C., Tesh, R. B., Tomonaga, K., Tordo, N., Towner, J. S., Vasilakis, N., Volchkov, V. E., Wahl-Jensen, V., Walker, P. J., Wang, B., Wang, D., Wang, F., Wang, L. F., Werren, J. H., Whitfield, A. E., Yan, Z., Ye, G. & Kuhn, J. H., Aug 1 2017, In : Archives of virology. 162, 8, p. 2493-2504 12 p.

Research output: Contribution to journalArticle

127 Scopus citations
2018

Protein Phosphatase 1-Targeting Small-Molecule C31 Inhibits Ebola Virus Replication

Ammosova, T., Pietzsch, C. A., Saygideǧer, Y., Ilatovsky, A., Lin, X., Ivanov, A., Kumari, N., Jerebtsova, M., Kulkarni, A., Petukhov, M., Üren, A., Bukreyev, A. & Nekhai, S., Nov 22 2018, In : Journal of Infectious Diseases. 218, p. S627-S635

Research output: Contribution to journalArticle

2 Scopus citations

Asymmetric antiviral effects of ebolavirus antibodies targeting glycoprotein stem and glycan cap

Ilinykh, P. A., Santos, R. I., Gunn, B. M., Kuzmina, N. A., Shen, X., Huang, K., Gilchuk, P., Flyak, A. I., Younan, P., Alter, G., Crowe, J. E. & Bukreyev, A., Aug 2018, In : PLoS pathogens. 14, 8, e1007204.

Research output: Contribution to journalArticle

5 Scopus citations

Ebolavirus Chimerization for the Development of a Mouse Model for Screening of Bundibugyo-Specific Antibodies

Ilinykh, P. A., Graber, J., Kuzmina, N. A., Huang, K., Ksiazek, T. G., Crowe, J. E. & Bukreyev, A., Nov 22 2018, In : Journal of Infectious Diseases. 218, p. S418-S422

Research output: Contribution to journalArticle

1 Scopus citations
2019

Antibody-mediated protective mechanisms induced by a trivalent parainfluenza virus-vectored ebolavirus vaccine

Brian Kimble, J., Malherbe, D. C., Meyer, M., Gunn, B. M., Karim, M. M., Ilinykh, P. A., Iampietro, M., Mohamed, K. S., Negi, S., Gilchuk, P., Huang, K., Wolf, Y. I., Braun, W., Crowe, J. E., Alter, G. & Bukreyev, A., Feb 1 2019, In : Journal of virology. 93, 4, e0184518.

Research output: Contribution to journalArticle

1 Scopus citations
2020
3 Scopus citations
2017

Ebola virus glycoprotein directly triggers T lymphocyte death despite of the lack of infection

Iampietro, M., Younan, P., Nishida, A., Dutta, M., Lubaki, N. M., Santos, R. I., Koup, R. A., Katze, M. G. & Bukreyev, A., May 2017, In : PLoS pathogens. 13, 5, e1006397.

Research output: Contribution to journalArticle

22 Scopus citations
2020

Non-neutralizing Antibodies from a Marburg Infection Survivor Mediate Protection by Fc-Effector Functions and by Enhancing Efficacy of Other Antibodies

Ilinykh, P. A., Huang, K., Santos, R. I., Gilchuk, P., Gunn, B. M., Karim, M. M., Liang, J., Fouch, M. E., Davidson, E., Parekh, D. V., Kimble, J. B., Pietzsch, C. A., Meyer, M., Kuzmina, N. A., Zeitlin, L., Saphire, E. O., Alter, G., Crowe, J. E. & Bukreyev, A., Jun 10 2020, In : Cell Host and Microbe. 27, 6, p. 976-991.e11

Research output: Contribution to journalArticle

2 Scopus citations
2011

Respiratory syncytial virus interferon antagonist NS1 protein suppresses and skews the human T lymphocyte response

Munir, S., Hillyer, P., le Nouën, C., Buchholz, U. J., Rabin, R. L., Collins, P. L. & Bukreyev, A., Apr 2011, In : PLoS pathogens. 7, 4, e1001336.

Research output: Contribution to journalArticle

78 Scopus citations
2020

Topoisomerase III-β is required for efficient replication of positive-sense RNA viruses

Kambham, R., Hirano, M., Fagg, W. S., McAnarney, E. T., Shan, C., Xie, X., Hage, A., Pietzsch, C. A., Bukreyev, A., Rajsbaum Gorodezky, R., Shi, P. Y., Bedford, M. T., Bradrick, S., Menachery, V. & Garcia-Blanco, M., Oct 2020, In : Antiviral research. 182, 104874.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations

Analysis of a Therapeutic Antibody Cocktail Reveals Determinants for Cooperative and Broad Ebolavirus Neutralization

Gilchuk, P., Murin, C. D., Milligan, J. C., Cross, R. W., Mire, C. E., Ilinykh, P. A., Huang, K., Kuzmina, N., Altman, P. X., Hui, S., Gunn, B. M., Bryan, A. L., Davidson, E., Doranz, B. J., Turner, H. L., Alkutkar, T., Flinko, R., Orlandi, C., Carnahan, R., Nargi, R. & 13 others, Bombardi, R. G., Vodzak, M. E., Li, S., Okoli, A., Ibeawuchi, M., Ohiaeri, B., Lewis, G. K., Alter, G., Bukreyev, A., Saphire, E. O., Geisbert, T. W., Ward, A. B. & Crowe, J. E., Feb 18 2020, In : Immunity. 52, 2, p. 388-403.e12

Research output: Contribution to journalArticle

Open Access
6 Scopus citations
2018

A high throughput screen identifies benzoquinoline compounds as inhibitors of Ebola virus replication

Luthra, P., Liang, J., Pietzsch, C. A., Khadka, S., Edwards, M. R., Wei, S., De, S., Posner, B., Bukreyev, A., Ready, J. M. & Basler, C. F., Feb 2018, In : Antiviral research. 150, p. 193-201 9 p.

Research output: Contribution to journalArticle

18 Scopus citations

Inhibiting pyrimidine biosynthesis impairs Ebola virus replication through depletion of nucleoside pools and activation of innate immune responses

Luthra, P., Naidoo, J., Pietzsch, C. A., De, S., Khadka, S., Anantpadma, M., Williams, C. G., Edwards, M. R., Davey, R. A., Bukreyev, A., Ready, J. M. & Basler, C. F., Oct 2018, In : Antiviral research. 158, p. 288-302 15 p.

Research output: Contribution to journalArticle

18 Scopus citations
2020

Global phosphoproteomic analysis of Ebola virions reveals a novel role for VP35 phosphorylation-dependent regulation of genome transcription

Ivanov, A., Ramanathan, P., Parry, C., Ilinykh, P. A., Lin, X., Petukhov, M., Obukhov, Y., Ammosova, T., Amarasinghe, G. K., Bukreyev, A. & Nekhai, S., Jul 1 2020, In : Cellular and Molecular Life Sciences. 77, 13, p. 2579-2603 25 p.

Research output: Contribution to journalArticle

2 Scopus citations
2019

Structural basis of broad ebolavirus neutralization by a human survivor antibody

West, B. R., Wec, A. Z., Moyer, C. L., Fusco, M. L., Ilinykh, P. A., Huang, K., Wirchnianski, A. S., James, R. M., Herbert, A. S., Hui, S., Goodwin, E., Howell, K. A., Kailasan, S., Aman, M. J., Walker, L. M., Dye, J. M., Bukreyev, A., Chandran, K. & Saphire, E. O., Mar 1 2019, In : Nature Structural and Molecular Biology. 26, 3, p. 204-212 9 p.

Research output: Contribution to journalArticle

7 Scopus citations
2018

Disruption of Phosphatidylserine Synthesis or Trafficking Reduces Infectivity of Ebola Virus

Younan, P., Iampietro, M., Santos, R. I., Ramanathan, P., Popov, V. L. & Bukreyev, A., Nov 22 2018, In : Journal of Infectious Diseases. 218, p. S475-S485

Research output: Contribution to journalArticle

2 Scopus citations
2019

Cross-reactive neutralizing human survivor monoclonal antibody BDBV223 targets the ebolavirus stalk

King, L. B., West, B. R., Moyer, C. L., Gilchuk, P., Flyak, A., Ilinykh, P. A., Bombardi, R., Hui, S., Huang, K., Bukreyev, A., Crowe, J. E. & Saphire, E. O., Dec 1 2019, In : Nature communications. 10, 1, 1788.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations
2014

Role of protein phosphatase 1 in dephosphorylation of Ebola virus VP30 protein and its targeting for the inhibition of viral transcription

Ilinykh, P. A., Tigabu, B., Ivanov, A., Ammosova, T., Obukhov, Y., Garron, T., Kumari, N., Kovalskyy, D., Platonov, M. O., Naumchik, V. S., Freiberg, A. N., Nekhai, S. & Bukreyev, A., Aug 15 2014, In : Journal of Biological Chemistry. 289, 33, p. 22723-22738 16 p.

Research output: Contribution to journalArticle

50 Scopus citations
2019

Taxonomy of the order Mononegavirales: second update 2018

Maes, P., Amarasinghe, G. K., Ayllón, M. A., Basler, C. F., Bavari, S., Blasdell, K. R., Briese, T., Brown, P. A., Bukreyev, A., Balkema-Buschmann, A., Buchholz, U. J., Chandran, K., Crozier, I., de Swart, R. L., Dietzgen, R. G., Dolnik, O., Domier, L. L., Drexler, J. F., Dürrwald, R., Dundon, W. G. & 57 others, Duprex, W. P., Dye, J. M., Easton, A. J., Fooks, A. R., Formenty, P. B. H., Fouchier, R. A. M., Freitas-Astúa, J., Ghedin, E., Griffiths, A., Hewson, R., Horie, M., Hurwitz, J. L., Hyndman, T. H., Jiāng, D., Kobinger, G. P., Kondō, H., Kurath, G., Kuzmin, I. V., Lamb, R. A., Lee, B., Leroy, E. M., Lǐ, J., Marzano, S. Y. L., Mühlberger, E., Netesov, S. V., Nowotny, N., Palacios, G., Pályi, B., Pawęska, J. T., Payne, S. L., Rima, B. K., Rota, P., Rubbenstroth, D., Simmonds, P., Smither, S. J., Song, Q., Song, T., Spann, K., Stenglein, M. D., Stone, D. M., Takada, A., Tesh, R. B., Tomonaga, K., Tordo, N., Towner, J. S., van den Hoogen, B., Vasilakis, N., Wahl, V., Walker, P. J., Wang, D., Wang, L. F., Whitfield, A. E., Williams, J. V., Yè, G., Zerbini, F. M., Zhang, Y. Z. & Kuhn, J. H., Apr 3 2019, In : Archives of virology. 164, 4, p. 1233-1244 12 p.

Research output: Contribution to journalArticle

Open Access
32 Scopus citations