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• 2017

  Potential role of DNA methylation as a facilitator of target search processes for transcription factors through interplay with methyl-CpG-binding proteins

  Kemme, C. A., Marquez, R., Luu, R. H. & Iwahara, J., Jul 1 2017, In: Nucleic acids research. 45, 13, p. 7751-7759 9 p.

  Research output: Contribution to journal › Article › peer-review

  • DNA Methylation
  • Carrier Proteins
  • Transcription Factors
  • Methyl CpG Binding Domain
  • CpG Islands
  5 Scopus citations

• Discrete-State Kinetics Model for NMR-Based Analysis of Protein Translocation on DNA at Equilibrium

  Sahu, D. & Iwahara, J., Oct 19 2017, In: Journal of Physical Chemistry B. 121, 41, p. 9548-9556 9 p.

  Research output: Contribution to journal › Article › peer-review

  • Nuclear magnetic resonance
  • DNA
  • Proteins
  • deoxyribonucleic acid
  • proteins
  4 Scopus citations
• 2011

  Dynamics of lysine side-chain amino groups in a protein studied by heteronuclear ¹H-¹⁵N NMR spectroscopy

  Esadze, A., Li, D. W., Wang, T., Brüschweiler, R. & Iwahara, J., Feb 2 2011, In: Journal of the American Chemical Society. 133, 4, p. 909-919 11 p.

  Research output: Contribution to journal › Article › peer-review

  • Nuclear magnetic resonance spectroscopy
  • Proton Magnetic Resonance Spectroscopy
  • Lysine
  • Proteins
  • Magnetic Resonance Spectroscopy
  60 Scopus citations
• 2012

  Asymmetrical roles of zinc fingers in dynamic DNA-scanning process by the inducible transcription factor Egr-1

  Zandarashvili, L., Vuzman, D., Esadze, A., Takayama, Y., Sahu, D., Levy, Y. & Iwahara, J., Jun 26 2012, In: Proceedings of the National Academy of Sciences of the United States of America. 109, 26, p. E1724-E1732

  Research output: Contribution to journal › Article › peer-review

  • Zinc Fingers
  • Transcription Factors
  • DNA
  • Kinetics
  • Mutant Proteins
  74 Scopus citations
• 2019

  Mobility of Histidine Side Chains Analyzed with ¹⁵ N NMR Relaxation and Cross-Correlation Data: Insight into Zinc-Finger-DNA Interactions

  Kemme, C. A., Luu, R. H., Chen, C., Pletka, C. C., Pettitt, B. M. & Iwahara, J., May 2 2019, In: Journal of Physical Chemistry B. 123, 17, p. 3706-3710 5 p.

  Research output: Contribution to journal › Article › peer-review

  • histidine
  • Nuclear magnetic resonance
  • Histidine
  • Zinc
  • DNA
  1 Scopus citations
• 2011

  Signature of mobile hydrogen bonding of lysine side chains from long-range ¹⁵N-¹³C scalar J-couplings and computation

  Zandarashvili, L., Li, D. W., Wang, T., Brüschweiler, R. & Iwahara, J., Jun 22 2011, In: Journal of the American Chemical Society. 133, 24, p. 9192-9195 4 p.

  Research output: Contribution to journal › Article › peer-review

  • Hydrogen bonds
  • Hydrogen Bonding
  • Hydrogen
  • Lysine
  • Molecular Dynamics Simulation
  29 Scopus citations
• 2017

  A unique and simple approach to improve sensitivity in ¹⁵N-NMR relaxation measurements for NH₃⁺ groups: Application to a protein-DNA complex

  Nguyen, D., Lokesh, G. L. R., Volk, D. E. & Iwahara, J., Aug 2017, In: Molecules. 22, 8, 1355.

  Research output: Contribution to journal › Article › peer-review

  • Nuclear magnetic resonance
  • Lysine
  • deoxyribonucleic acid
  • proteins
  • nuclear magnetic resonance
  4 Scopus citations
• 2014

  Positive and negative impacts of nonspecific sites during target location by a sequence-specific DNA-binding protein: Origin of the optimal search at physiological ionic strength

  Esadze, A., Kemme, C. A., Kolomeisky, A. B. & Iwahara, J., 2014, In: Nucleic acids research. 42, 11, p. 7039-7046 8 p.

  Research output: Contribution to journal › Article › peer-review

  • DNA-Binding Proteins
  • Osmolar Concentration
  • Zinc Fingers
  • Kinetics
  • DNA
  51 Scopus citations
• 2019

  Experimental Evidence of Solvent-Separated Ion Pairs as Metastable States in Electrostatic Interactions of Biological Macromolecules

  Yu, B., Pettitt, B. M. & Iwahara, J., Dec 19 2019, In: Journal of Physical Chemistry Letters. 10, 24, p. 7937-7941 5 p.

  Research output: Contribution to journal › Article › peer-review

  • Coulomb interactions
  • Macromolecules
  • macromolecules
  • metastable state
  • Ions
  1 Scopus citations
• 2014

  Effective strategy to assign ¹H-¹⁵N heteronuclear correlation NMR signals from lysine side-chain NH<inf>3</inf> ⁺ groups of proteins at low temperature

  Esadze, A., Zandarashvili, L. & Iwahara, J., 2014, In: Journal of Biomolecular NMR. 60, 1, p. 23-27 5 p.

  Research output: Contribution to journal › Article › peer-review

  • Biomolecular Nuclear Magnetic Resonance
  • Nuclear magnetic resonance
  • Lysine
  • Temperature
  • Pair Bond
  15 Scopus citations

• Stopped-flow fluorescence kinetic study of protein sliding and intersegment transfer in the target DNA search process

  Esadze, A. & Iwahara, J., Jan 9 2014, In: Journal of Molecular Biology. 426, 1, p. 230-244 15 p.

  Research output: Contribution to journal › Article › peer-review

  • Fluorescence
  • Kinetics
  • DNA
  • Zinc Fingers
  • Proteins
  42 Scopus citations
• 2017

  Internal Motions of Basic Side Chains of the Antennapedia Homeodomain in the Free and DNA-Bound States

  Nguyen, D., Hoffpauir, Z. A. & Iwahara, J., Nov 7 2017, In: Biochemistry. 56, 44, p. 5866-5869 4 p.

  Research output: Contribution to journal › Article › peer-review

  • DNA
  • Molecular recognition
  • Nuclear magnetic resonance spectroscopy
  • Hydrogen bonds
  • Thymine
  13 Scopus citations