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Author

  • Tetsuro Ikegami
2015

Rift Valley fever virus MP-12 vaccine is fully attenuated by a combination of partial attenuations in the S, M, and L segments

Ikegami, T., Hill, T. E., Smith, J. K., Zhang, L., Juelich, T. L., Gong, B., Slack, O. A. L., Ly, H. J., Lokugamage, N. & Freiberg, A., 2015, In : Journal of Virology. 89, 14, p. 7262-7276 15 p.

Research output: Contribution to journalArticle

25 Scopus citations
2017

Rift Valley fever vaccines: an overview of the safety and efficacy of the live-attenuated MP-12 vaccine candidate

Ikegami, T., Jun 3 2017, In : Expert Review of Vaccines. 16, 6, p. 601-611 11 p.

Research output: Contribution to journalReview article

16 Scopus citations
2018

Rift Valley fever vaccines: current and future needs

Dungu, B., Lubisi, B. A. & Ikegami, T., Apr 1 2018, In : Current Opinion in Virology. 29, p. 8-15 8 p.

Research output: Contribution to journalReview article

9 Scopus citations
2015

MP-12 virus containing the clone 13 deletion in the NSs gene prevents lethal disease when administered after Rift Valley fever virus infection in hamsters

Gowen, B. B., Westover, J. B., Sefing, E. J., Bailey, K. W., Nishiyama, S., Wandersee, L., Scharton, D., Jung, K. H. & Ikegami, T., Jan 1 2015, In : Frontiers in Microbiology. 6, JUN, 651.

Research output: Contribution to journalArticle

4 Scopus citations
2019

Candidate vaccines for human Rift Valley fever

Ikegami, T., Jan 1 2019, (Accepted/In press) In : Expert Opinion on Biological Therapy.

Research output: Contribution to journalReview article

2013

The Dominant-negative inhibition of double-stranded RNA-Dependent protein kinase PKR increases the efficacy of rift valley fever virus MP-12 vaccine

Lihoradova, O., Kalveram, B., Indran, S. V., Lokugamage, N., Juelich, T. L., Hill, T. E., Tseng, C. T. K., Gong, B., Fukushi, S., Morikawa, S., Freiberg, A. N. & Ikegami, T., Oct 29 2013, In : Journal of virology. 87, 22, 1 p.

Research output: Contribution to journalComment/debate

2018

Favipiravir (T-705) protects against Nipah virus infection in the hamster model /631/326/22/1295 /631/326/596/1296 /13/106 /14/35 /38/77 /82/51 /96/63 article

Dawes, B. E., Kalveram, B., Ikegami, T., Juelich, T., Smith, J. K., Zhang, L., Park, A., Lee, B., Komeno, T., Furuta, Y. & Freiberg, A., Dec 1 2018, In : Scientific Reports. 8, 1, 7604.

Research output: Contribution to journalArticle

26 Scopus citations
2013

Toscana virus NSs protein promotes degradation of double-stranded RNA-dependent protein kinase

Kalveram, B. & Ikegami, T., Apr 2013, In : Journal of virology. 87, 7, p. 3710-3718 9 p.

Research output: Contribution to journalArticle

20 Scopus citations
2011

The pathogenesis of rift valley fever

Ikegami, T. & Makino, S., May 1 2011, In : Viruses. 3, 5, p. 493-519 27 p.

Research output: Contribution to journalReview article

153 Scopus citations
2016

The L, M, and S segments of Rift Valley fever virus MP-12 vaccine independently contribute to a temperature-sensitive phenotype

Nishiyama, S., Lokugamage, N. & Ikegami, T., 2016, In : Journal of Virology. 90, 7, p. 3735-3744 10 p.

Research output: Contribution to journalArticle

10 Scopus citations
2017

Risk analysis of inter-species reassortment through a Rift Valley fever phlebovirus MP-12 vaccine strain

Ly, H. J., Lokugamage, N., Nishiyama, S. & Ikegami, T., Sep 2017, In : PloS one. 12, 9, e0185194.

Research output: Contribution to journalArticle

5 Scopus citations
2016

Mutational analysis of the rift valley fever virus glycoprotein precursor proteins for Gn protein expression

Phoenix, I., Lokugamage, N., Nishiyama, S. & Ikegami, T., Jun 2016, In : Viruses. 8, 6, 151.

Research output: Contribution to journalArticle

6 Scopus citations
2019

Identification and evaluation of antivirals for Rift Valley fever virus

Lang, Y., Li, Y., Jasperson, D., Henningson, J., Lee, J., Ma, J., Li, Y., Duff, M., Liu, H., Bai, D., McVey, S., Richt, J. A., Ikegami, T., Wilson, W. C. & Ma, W., Mar 2019, In : Veterinary Microbiology. 230, p. 110-116 7 p.

Research output: Contribution to journalArticle

3 Scopus citations
2011

Using reverse genetics to manipulate the NSs gene of the rift valley fever virus MP-12 strain to improve vaccine safety and efficacy

Kalveram, B., Lihoradova, O., Indran, S. V. & Ikegami, T., Nov 2011, In : Journal of Visualized Experiments. 57, e3400.

Research output: Contribution to journalArticle

22 Scopus citations
2016

Optimized P2A for reporter gene insertion into nipah virus results in efficient ribosomal skipping and wild-type lethality

Park, A., Yun, T., Hill, T. E., Ikegami, T., Juelich, T. L., Smith, J. K., Zhang, L., Freiberg, A. & Lee, B., Apr 1 2016, In : Journal of General Virology. 97, 4, p. 839-843 5 p.

Research output: Contribution to journalArticle

6 Scopus citations

Rift Valley fever virus NSs protein functions and the similarity to other bunyavirus NSs proteins

Ly, H. J. & Ikegami, T., Jul 2 2016, In : Virology journal. 13, 1, 118.

Research output: Contribution to journalArticle

30 Scopus citations
2018

Experimental Infection of Syrian Hamsters with Aerosolized Nipah Virus

Escaffre, O., Hill, T., Ikegami, T., Juelich, T. L., Smith, J. K., Zhang, L., Perez, D. E., Atkins, C., Park, A., Lawrence, W., Sivasubramani, S. K., Peel, J. E., Peterson, J., Lee, B. & Freiberg, A., Oct 5 2018, In : Journal of Infectious Diseases. 218, 10, p. 1602-1610 9 p.

Research output: Contribution to journalArticle

4 Scopus citations
2013

Post-exposure vaccination with MP-12 lacking NSs protects mice against lethal Rift Valley fever virus challenge

Gowen, B. B., Bailey, K. W., Scharton, D., Vest, Z., Westover, J. B., Skirpstunas, R. & Ikegami, T., Apr 16 2013, In : Antiviral research. 98, 2, p. 135-143 9 p.

Research output: Contribution to journalArticle

14 Scopus citations
2011

Reston ebolavirus antibodies in bats, the Philippines

Taniguchi, S., Watanabe, S., Masangkay, J. S., Omatsu, T., Ikegami, T., Alviola, P., Ueda, N., Iha, K., Fujii, H., Ishii, Y., Mizutani, T., Fukushi, S., Saijo, M., Kurane, I., Kyuwa, S., Akashi, H., Yoshikawa, Y. & Morikawa, S., Aug 2011, In : Emerging infectious diseases. 17, 8, p. 1559-1560 2 p.

Research output: Contribution to journalLetter

63 Scopus citations
2015
4 Scopus citations
2011

NSs protein of rift valley fever virus promotes posttranslational downregulation of the TFIIH subunit p62

Kalveram, B., Lihoradova, O. & Ikegami, T., Jul 1 2011, In : Journal of virology. 85, 13, p. 6234-6243 10 p.

Research output: Contribution to journalArticle

78 Scopus citations
2016

Application of droplet digital PCR to validate rift valley fever vaccines

Ly, H. J., Lokugamage, N. & Ikegami, T., Apr 1 2016, Methods in Molecular Biology. Humana Press Inc., Vol. 1403. p. 207-220 14 p. (Methods in Molecular Biology; vol. 1403).

Research output: Chapter in Book/Report/Conference proceedingChapter

2 Scopus citations
2013

Using click chemistry to measure the effect of viral infection on host-cell RNA synthesis

Kalveram, B., Lihoradova, O., Indran, S. V., Head, J. A. & Ikegami, T., Jan 1 2013, In : Journal of visualized experiments : JoVE. 78

Research output: Contribution to journalArticle

8 Scopus citations
2016

N-glycans on the rift valley fever virus envelope glycoproteins Gn and Gc redundantly support viral infection via DC-SIGN

Phoenix, I., Nishiyama, S., Lokugamage, N., Hill, T. E., Huante, M. B., Slack, O. A. L., Carpio, V. H., Freiberg, A. N. & Ikegami, T., May 23 2016, In : Viruses. 8, 5

Research output: Contribution to journalArticle

8 Scopus citations

Attenuation of pathogenic Rift Valley fever virus strain through the chimeric S-segment encoding sandfly fever phlebovirus NSs or a dominant-negative PKR

Nishiyama, S., Slack, O. A. L., Lokugamage, N., Hill, T. E., Juelich, T. L., Zhang, L., Smith, J. K., Perez, D., Gong, B., Freiberg, A. & Ikegami, T., Jun 16 2016, (Accepted/In press) In : Virulence. p. 1-11 11 p.

Research output: Contribution to journalArticle

9 Scopus citations
2013

Rift Valley fever virus NSs inhibits host transcription independently of the degradation of dsRNA-dependent protein kinase PKR

Kalveram, B., Lihoradova, O., Indran, S. V., Lokugamage, N., Head, J. A. & Ikegami, T., Jan 20 2013, In : Virology. 435, 2, p. 415-424 10 p.

Research output: Contribution to journalArticle

24 Scopus citations

Characterization of Rift Valley Fever Virus MP-12 Strain Encoding NSs of Punta Toro Virus or Sandfly Fever Sicilian Virus

Lihoradova, O. A., Indran, S. V., Kalveram, B., Lokugamage, N., Head, J. A., Gong, B., Tigabu, B., Juelich, T. L., Freiberg, A. N. & Ikegami, T., Apr 2013, In : PLoS neglected tropical diseases. 7, 4, e2181.

Research output: Contribution to journalArticle

20 Scopus citations

Rift valley fever virus MP-12 vaccine encoding toscana virus NSs retains neuroinvasiveness in mice

Indran, S. V., Lihoradova, O. A., Phoenix, I., Lokugamage, N., Kalveram, B., Head, J. A., Tigabu, B., Smith, J. K., Zhang, L., Juelich, T. L., Gong, B., Freiberg, A. N. & Ikegami, T., Jul 1 2013, In : Journal of General Virology. 94, PART7, p. 1441-1450 10 p.

Research output: Contribution to journalArticle

12 Scopus citations
2017

Contribution of human lung parenchyma and leukocyte influx to oxidative stress and immune systemmediated pathology following Nipah virus infection

Escaffre, O., Saito, T., Juelich, T. L., Ikegami, T., Smith, J. K., Perez, D. D., Atkins, C., Levine, C. B., Huante, M., Nusbaum, R. J., Endsley, J., Freiberg, A. & Rockx, B., Aug 1 2017, In : Journal of Virology. 91, 15, e00275-17.

Research output: Contribution to journalArticle

5 Scopus citations
2014

Countermeasure development for rift valley fever: Deletion, modification or targeting of major virulence factor NSs

Lihoradova, O. & Ikegami, T., Jan 1 2014, In : Future Virology. 9, 1, p. 27-39 13 p.

Research output: Contribution to journalReview article

8 Scopus citations
2019

Rescue of infectious Arumowot virus from cloned cDNA: Posttranslational degradation of Arumowot virus NSs protein in human cells

Hallam, H. J., Lokugamage, N. & Ikegami, T., 2019, In : PLoS neglected tropical diseases. 13, 11, e0007904.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations
2017

Distinct virulence of Rift Valley fever phlebovirus strains from different genetic lineages in a mouse model

Ikegami, T., Balogh, A., Nishiyama, S., Lokugamage, N., Saito, T. B., Morrill, J. C., Shivanna, V., Indran, S. V., Zhang, L., Smith, J. K., Perez, D., Juelich, T. L., Morozov, I., Wilson, W. C., Freiberg, A. N. & Richt, J. A., Dec 2017, In : PloS one. 12, 12, e0189250.

Research output: Contribution to journalArticle

5 Scopus citations

Genetic stability of Rift Valley fever virus MP-12 vaccine during serial passages in culture cells

Lokugamage, N. & Ikegami, T., Dec 1 2017, In : npj Vaccines. 2, 1, 20.

Research output: Contribution to journalArticle

5 Scopus citations

Attenuation and protective efficacy of Rift Valley fever phlebovirus rMP12-GM50 strain

Ly, H. J., Nishiyama, S., Lokugamage, N., Smith, J. K., Zhang, L., Perez, D., Juelich, T. L., Freiberg, A. N. & Ikegami, T., 2017, (Accepted/In press) In : Vaccine.

Research output: Contribution to journalArticle

6 Scopus citations