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• 2019

  Bile Salts Alter the Mouse Norovirus Capsid Conformation: Possible Implications for Cell Attachment and Immune Evasion

  Sherman, M. B., Williams, A. N., Smith, H. Q., Nelson, C., Wilen, C. B., Fremont, D. H., Virgin, H. W. & Smith, T. J., Oct 1 2019, In: Journal of virology. 93, 19

  Research output: Contribution to journal › Article › peer-review

  • immune evasion
  • Norovirus
  • Immune Evasion
  • bile salts
  • capsid
  11 Scopus citations
• 2012

  Glutamate dehydrogenase: Structure, regulation, and its role in insulin homeostasis

  Smith, T. J., Apr 4 2012, Monogenic Hyperinsulinemic Hypoglycemia Disorders. Charles, S. & Diva, D. L. (eds.). p. 87-99 13 p. (Frontiers in Diabetes; vol. 21).

  Research output: Chapter in Book/Report/Conference proceeding › Chapter

  • Glutamate Dehydrogenase
  • Allosteric Regulation
  • Homeostasis
  • Insulin
  • Naphazoline
• 2017

  A severe case of hyperinsulinism due to hemizygous activating mutation of glutamate dehydrogenase

  Barrosse-Antle, M., Su, C., Chen, P., Boodhansingh, K. E., Smith, T. J., Stanley, C. A., De León, D. D. & Li, C., Dec 2017, In: Pediatric Diabetes. 18, 8, p. 911-916 6 p.

  Research output: Contribution to journal › Article › peer-review

  • Glutamate Dehydrogenase
  • Hyperinsulinism
  • Guanosine Triphosphate
  • Mutation
  • Heterozygote
  9 Scopus citations
• 2012

  Structural basis for broad detection of genogroup II noroviruses by a monoclonal antibody that binds to a site occluded in the viral particle

  Hansman, G. S., Taylor, D. W., McLellan, J. S., Smith, T. J., Georgiev, I., Tame, J. R. H., Park, S. Y., Yamazaki, M., Gondaira, F., Miki, M., Katayama, K., Murata, K. & Kwong, P. D., Apr 2012, In: Journal of virology. 86, 7, p. 3635-3646 12 p.

  Research output: Contribution to journal › Article › peer-review

  • Norovirus
  • virus-like particles
  • virion
  • Virion
  • monoclonal antibodies
  50 Scopus citations
• 2017

  Antibody-induced uncoating of human rhinovirus B14

  Dong, Y., Liu, Y., Jiang, W., Smith, T. J., Xu, Z. & Rossmann, M. G., Jul 25 2017, In: Proceedings of the National Academy of Sciences of the United States of America. 114, 30, p. 8017-8022 6 p.

  Research output: Contribution to journal › Article › peer-review

  • Rhinovirus
  • Capsid
  • Antibodies
  • Virus Uncoating
  • Cryoelectron Microscopy
  27 Scopus citations
• 2014

  Editorial overview: Theory and simulation: Macromolecular machines

  Hopfner, K. P. & Smith, T. J., Apr 2014, In: Current Opinion in Structural Biology. 25, p. 6-8 3 p.

  Research output: Contribution to journal › Editorial › peer-review

• Glutamate dehydrogenase: Structure, allosteric regulation, and role in insulin homeostasis

  Li, M., Li, C., Allen, A., Stanley, C. A. & Smith, T. J., Mar 1 2014, In: Neurochemical Research. 39, 3, p. 433-445 13 p.

  Research output: Contribution to journal › Review article › peer-review

  • Allosteric Regulation
  • Glutamate Dehydrogenase
  • Homeostasis
  • Insulin
  • Guanosine Triphosphate
  28 Scopus citations
• 2017

  Stability of cucumber necrosis virus at the quasi-6-fold axis affects zoospore transmission

  Sherman, M. B., Kakani, K., Rochon, DA., Jiang, W., Voss, N. R. & Smith, T. J., Oct 1 2017, In: Journal of virology. 91, 19, e01030-17.

  Research output: Contribution to journal › Article › peer-review

  • Cucumber necrosis virus
  • zoospores
  • Zinc
  • Tombusvirus
  • capsid
  2 Scopus citations
• 2019

  Glutamate dehydrogenase: Structure of a hyperinsulinism mutant, corrections to the atomic model, and insights into a regulatory site

  Nassar, O. M., Li, C., Stanley, C. A., Pettitt, B. M. & Smith, T. J., Jan 2019, In: Proteins: Structure, Function and Bioinformatics. 87, 1, p. 41-50 10 p.

  Research output: Contribution to journal › Article › peer-review

  • Hyperinsulinemic hypoglycemia, familial, 6
  • Glutamate Dehydrogenase
  • Hyperinsulinism
  • Crystal structure
  • Free energy
  4 Scopus citations
• 2012

  The structure and allosteric regulation of mammalian glutamate dehydrogenase

  Li, M., Li, C., Allen, A., Stanley, C. A. & Smith, T. J., Mar 15 2012, In: Archives of Biochemistry and Biophysics. 519, 2, p. 69-80 12 p.

  Research output: Contribution to journal › Review article › peer-review

  • Allosteric Regulation
  • Glutamate Dehydrogenase
  • Guanosine Triphosphate
  • Hyperinsulinemic hypoglycemia, familial, 6
  • Animals
  77 Scopus citations
• 2019

  Dissecting the Antenna in Human Glutamate Dehydrogenase: Understanding Its Role in Subunit Communication and Allosteric Regulation

  Hoffpauir, Z. A., Sherman, E. & Smith, T. J., Oct 15 2019, In: Biochemistry. 58, 41, p. 4195-4206 12 p.

  Research output: Contribution to journal › Article › peer-review

  • Allosteric Regulation
  • Glutamate Dehydrogenase
  • Communication
  • Antennas
  • Purine Nucleotides

• Glutamate Dehydrogenase, a Complex Enzyme at a Crucial Metabolic Branch Point

  Smith, H. Q., Li, C., Stanley, C. A. & Smith, T. J., Jan 15 2019, In: Neurochemical Research. 44, 1, p. 117-132 16 p.

  Research output: Contribution to journal › Article › peer-review

  • Glutamate Dehydrogenase
  • Animals
  • Enzymes
  • Naphazoline
  • Metabolites
  12 Scopus citations
• 2014

  Flexibility in surface-exposed loops in a virus capsid mediates escape from antibody neutralization

  Kolawole, A. O., Li, M., Xia, C., Fischer, A. E., Giacobbi, N. S., Rippinger, C. M., Proescher, J. B. G., Wu, S. K., Bessling, S. L., Gamez, M., Yu, C., Zhang, R., Mehoke, T. S., Pipas, J. M., Wolfe, J. T., Lin, J. S., Feldman, A. B., Smith, T. J. & Wobus, C. E., Apr 2014, In: Journal of virology. 88, 8, p. 4543-4557 15 p.

  Research output: Contribution to journal › Article › peer-review

  • Norovirus
  • capsid
  • Capsid
  • neutralization
  • Viruses
  23 Scopus citations

• Newly isolated mAbs broaden the neutralizing epitope in murine norovirus

  Kolawole, A. O., Xia, C., Li, M., Gamez, M., Yu, C., Rippinger, C. M., Yucha, R. E., Smith, T. J. & Wobus, C. E., Sep 2014, In: Journal of General Virology. 95, PART 9, p. 1958-1968 11 p.

  Research output: Contribution to journal › Article › peer-review

  • Norovirus
  • Epitopes
  • Antibodies
  • Immunoglobulin A
  • Viruses
  9 Scopus citations
• 2020

  The dynamic life of virus capsids

  Sherman, M. B., Smith, H. Q. & Smith, T. J., Jun 2020, In: Viruses. 12, 6, 618.

  Research output: Contribution to journal › Review article › peer-review

  Open Access

  • Capsid
  • Viruses
  • Rhinovirus
  • Norovirus
  • Immune System
• 2017

  Norovirus escape from broadly neutralizing antibodies is limited to allostery-like mechanisms

  Kolawole, A. O., Smith, H. Q., Svoboda, S. A., Lewis, M. S., Sherman, M. B., Lynch, G. C., Pettitt, B. M., Smith, T. J. & Wobus, C. E., Sep 1 2017, In: mSphere. 2, 5, e00334-17.

  Research output: Contribution to journal › Article › peer-review

  • Norovirus
  • Neutralizing Antibodies
  • Antibodies
  • Mutation
  • Vaccines
  18 Scopus citations
• 2019

  Allosteric discrimination at the NADH/ADP regulatory site of glutamate dehydrogenase

  Nassar, O. M., Wong, K. Y., Lynch, G. C., Smith, T. J. & Pettitt, B. M., Dec 1 2019, In: Protein Science. 28, 12, p. 2080-2088 9 p.

  Research output: Contribution to journal › Article › peer-review

  • Glutamate Dehydrogenase
  • Diphosphates
  • Niacinamide
  • Hydrides
  • Adenine

• The dynamic capsid structures of the noroviruses

  Smith, H. Q. & Smith, T. J., Mar 2019, In: Viruses. 11, 3, 235.

  Research output: Contribution to journal › Review article › peer-review

  Open Access

  • Norovirus
  • Capsid
  • Herd Immunity
  • Capsid Proteins
  • Viral Genome
  6 Scopus citations
• 2012

  Protruding domain of capsid protein is necessary and sufficient to determine murine norovirus replication and pathogenesis in vivo

  Strong, D. W., Thackray, L. B., Smith, T. J. & Virgin, H. W., Mar 2012, In: Journal of virology. 86, 6, p. 2950-2958 9 p.

  Research output: Contribution to journal › Article › peer-review

  • Norovirus
  • Capsid Proteins
  • coat proteins
  • pathogenesis
  • mice
  54 Scopus citations

• Multidomain carbohydrate-binding proteins involved in Bacteroides thetaiotaomicron starch metabolism

  Cameron, E. A., Maynard, M. A., Smith, C. J., Smith, T. J., Koropatkin, N. M. & Martens, E. C., Oct 5 2012, In: Journal of Biological Chemistry. 287, 41, p. 34614-34625 12 p.

  Research output: Contribution to journal › Article › peer-review

  • Bacteroides thetaiotaomicron
  • saccharide-binding proteins
  • Metabolism
  • Starch
  • Carbohydrates
  58 Scopus citations