Find Research outputs

Search results

• 2014

  Brown adipose tissue improves whole-body glucose homeostasis and insulin sensitivity in humans

  Chondronikola, M., Volpi, E., Børsheim, E., Porter, C., Annamalai, P., Enerbäck, S., Lidell, M. E., Saraf, M. K., Labbe, S. M., Hurren, N. M., Yfanti, C., Chao, T., Andersen, C. R., Cesani, F., Hawkins, H. & Sidossis, L. S., Dec 1 2014, In: Diabetes. 63, 12, p. 4089-4099 11 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Brown Adipose Tissue
  • Insulin Resistance
  • Homeostasis
  • Glucose
  • Hypoglycemic Agents
  375 Scopus citations
• 2013

  Protein blend ingestion following resistance exercise promotes human muscle protein synthesis

  Reidy, P. T., Walker, D. K., Dickinson, J. M., Gundermann, D. M., Drummond, M. J., Timmerman, K. L., Fry, C. S., Borack, M. S., Cope, M. B., Mukherjea, R., Jennings, K., Volpi, E. & Rasmussen, B. B., Apr 1 2013, In: Journal of Nutrition. 143, 4, p. 410-416 7 p.

  Research output: Contribution to journal › Article › peer-review

  • Muscle Proteins
  • Eating
  • Whey Proteins
  • Exercise
  • Mechanistic Target of Rapamycin Complex 1
  86 Scopus citations
• 2015

  Protein intake and muscle function in older adults

  Deer, R. R. & Volpi, E., May 27 2015, In: Current Opinion in Clinical Nutrition and Metabolic Care. 18, 3, p. 248-253 6 p.

  Research output: Contribution to journal › Review article › peer-review

  • Muscle Proteins
  • Recommended Dietary Allowances
  • Sarcopenia
  • Dietary Proteins
  • Muscles
  75 Scopus citations
• 2013

  Rapamycin does not affect post-absorptive protein metabolism in human skeletal muscle

  Dickinson, J. M., Drummond, M. J., Fry, C. S., Gundermann, D. M., Walker, D. K., Timmerman, K. L., Volpi, E. & Rasmussen, B. B., Jan 2013, In: Metabolism: Clinical and Experimental. 62, 1, p. 144-151 8 p.

  Research output: Contribution to journal › Article › peer-review

  • Sirolimus
  • Skeletal Muscle
  • Mechanistic Target of Rapamycin Complex 1
  • Muscle Proteins
  • Proteins
  14 Scopus citations

• Exercise and nutrition to target protein synthesis impairments in aging skeletal muscle

  Dickinson, J. M., Volpi, E. & Rasmussen, B. B., Oct 1 2013, In: Exercise and Sport Sciences Reviews. 41, 4, p. 216-223 8 p.

  Research output: Contribution to journal › Article › peer-review

  • Sarcopenia
  • Muscle Proteins
  • Skeletal Muscle
  • Proteins
  68 Scopus citations
• 2014

  Leucine-enriched Amino acid ingestion after resistance exercise prolongs myofibrillar protein synthesis and amino acid transporter expression in older men

  Dickinson, J. M., Gundermann, D. M., Walker, D. K., Reidy, P. T., Borack, M. S., Drummond, M. J., Arora, M., Volpi, E. & Rasmussen, B. B., 2014, In: Journal of Nutrition. 144, 11, p. 1694-1702 9 p.

  Research output: Contribution to journal › Article › peer-review

  • Amino Acid Transport Systems
  • Leucine
  • Eating
  • Amino Acids
  • Exercise
  56 Scopus citations
• 2015

  Effect of age on basal muscle protein synthesis and mTORC1 signaling in a large cohort of young and older men and women

  Markofski, M. M., Dickinson, J. M., Drummond, M. J., Fry, C. S., Fujita, S., Gundermann, D. M., Glynn, E. L., Jennings, K., Paddon-Jones, D., Reidy, P. T., Sheffield-Moore, M., Timmerman, K. L., Rasmussen, B. B. & Volpi, E., May 1 2015, In: Experimental Gerontology. 65, p. 1-7 7 p.

  Research output: Contribution to journal › Article › peer-review

  • Mechanistic Target of Rapamycin Complex 1
  • Muscle Proteins
  • Muscle
  • Skeletal Muscle
  • Fats
  65 Scopus citations
• 2013

  Is the optimal level of protein intake for older adults greater than the recommended dietary allowance?

  Volpi, E., Campbell, W. W., Dwyer, J. T., Johnson, M. A., Jensen, G. L., Morley, J. E. & Wolfe, R. R., Jun 2013, In: Journals of Gerontology - Series A Biological Sciences and Medical Sciences. 68, 6, p. 677-681 5 p.

  Research output: Contribution to journal › Article › peer-review

  • Recommended Dietary Allowances
  • Proteins
  • Sarcopenia
  • Health
  • Nutrients
  201 Scopus citations

• Evidence-based recommendations for optimal dietary protein intake in older people: A position paper from the prot-age study group

  Bauer, J., Biolo, G., Cederholm, T., Cesari, M., Cruz-Jentoft, A. J., Morley, J. E., Phillips, S., Sieber, C., Stehle, P., Teta, D., Visvanathan, R., Volpi, E. & Boirie, Y., Aug 2013, In: Journal of the American Medical Directors Association. 14, 8, p. 542-559 18 p.

  Research output: Contribution to journal › Article › peer-review

  • Dietary Proteins
  • Age Groups
  • Proteins
  • Acute Disease
  • Body Weight
  921 Scopus citations
• 2014

  Insulin increases mRNA abundance of the amino acid transporter SLC7A5/LAT1 via an mTORC1-dependent mechanism in skeletal muscle cells

  Walker, D. K., Drummond, M. J., Dickinson, J. M., Borack, M. S., Jennings, K., Volpi, E. & Rasmussen, B. B., Mar 2014, In: Physiological reports. 2, 3, e00238.

  Research output: Contribution to journal › Article › peer-review

  • Large Neutral Amino Acid-Transporter 1
  • Amino Acid Transport Systems
  • Mechanistic Target of Rapamycin Complex 1
  • Muscle Cells
  • Skeletal Muscle
  21 Scopus citations
• 2013

  Skeletal muscle autophagy and protein breakdown following resistance exercise are similar in younger and older adults

  Fry, C. S., Drummond, M. J., Glynn, E. L., Dickinson, J. M., Gundermann, D. M., Timmerman, K. L., Walker, D. K., Volpi, E. & Rasmussen, B. B., May 2013, In: Journals of Gerontology - Series A Biological Sciences and Medical Sciences. 68, 5, p. 599-607 9 p.

  Research output: Contribution to journal › Article › peer-review

  • Muscle Proteins
  • Autophagy
  • Young Adult
  • Skeletal Muscle
  • Exercise
  96 Scopus citations
• 2020

  Effect of essential amino acid supplementation and aerobic exercise on insulin sensitivity in healthy older adults: A randomized clinical trial

  Randolph, A. C., Markofski, M. M., Rasmussen, B. B. & Volpi, E., May 2020, In: Clinical Nutrition. 39, 5, p. 1371-1378 8 p.

  Research output: Contribution to journal › Article › peer-review

  • Essential Amino Acids
  • Insulin Resistance
  • Randomized Controlled Trials
  • Exercise
  • Placebos

• Molecular Transducers of Physical Activity Consortium (MoTrPAC): Mapping the Dynamic Responses to Exercise

  the Molecular Transducers of Physical Activity Consortium, Jun 25 2020, In: Cell. 181, 7, p. 1464-1474 11 p.

  Research output: Contribution to journal › Review article › peer-review

  Open Access

  • Transducers
  • Dynamic response
  • Tissue
  • Rodentia
  8 Scopus citations
• 2013

  Endothelial function and the regulation of muscle protein anabolism in older adults

  Timmerman, K. L. & Volpi, E., 2013, In: Nutrition, Metabolism and Cardiovascular Diseases. 23, SUPPL1, p. S44eS50

  Research output: Contribution to journal › Review article › peer-review

  • Muscle Proteins
  • Sarcopenia
  • Insulin Resistance
  • Skeletal Muscle
  • Frailty
  30 Scopus citations

• Aging differentially affects human skeletal muscle amino acid transporter expression when essential amino acids are ingested after exercise

  Dickinson, J. M., Drummond, M. J., Coben, J. R., Volpi, E. & Rasmussen, B. B., Apr 2013, In: Clinical Nutrition. 32, 2, p. 273-280 8 p.

  Research output: Contribution to journal › Article › peer-review

  • Amino Acid Transport Systems
  • Essential Amino Acids
  • Skeletal Muscle
  • Exercise
  • Neutral Amino Acid Transport Systems
  48 Scopus citations
• 2014

  Activation of mTORC1 signaling and protein synthesis in human muscle following blood flow restriction exercise is inhibited by rapamycin

  Gundermann, D. M., Walker, D. K., Reidy, P. T., Borack, M. S., Dickinson, J. M., Volpi, E. & Rasmussen, B. B., May 15 2014, In: American Journal of Physiology - Endocrinology and Metabolism. 306, 10, p. E1198-E1204

  Research output: Contribution to journal › Article › peer-review

  • Mechanistic Target of Rapamycin Complex 1
  • Sirolimus
  • Exercise
  • Muscles
  • Muscle Proteins
  51 Scopus citations
• 2013

  Kyphoplasty for vertebral augmentation in the elderly with osteoporotic vertebral compression fractures: Scenarios and review of recent studies

  Bednar, T., Heyde, C. E., Bednar, G., Nguyen, D., Volpi, E. & Przkora, R., Nov 2013, In: Clinical Therapeutics. 35, 11, p. 1721-1727 7 p.

  Research output: Contribution to journal › Article › peer-review

  • Kyphoplasty
  • Compression Fractures
  • Elderly
  • Vertebroplasty
  • Osteoporosis
  8 Scopus citations
• 2020

  A randomized trial of a multifactorial strategy to prevent serious fall injuries

  Bhasin, S., Gill, T. M., Reuben, D. B., Latham, N. K., Ganz, D. A., Greene, E. J., Dziura, J., Basaria, S., Gurwitz, J. H., Dykes, P. C., McMahon, S., Storer, T. W., Gazarian, P., Miller, M. E., Travison, T. G., Esserman, D., Carnie, M. B., Goehring, L., Fagan, M., Greenspan, S. L. & 27 others, Alexander, N., Wiggins, J., Ko, F., Siu, A. L., Volpi, E., Wu, A. W., Rich, J., Waring, S. C., Wallace, R. B., Casteel, C., Resnick, N. M., Magaziner, J., Charpentier, P., Lu, C., Araujo, K., Rajeevan, H., Meng, C., Allore, H., Brawley, B. F., Eder, R., McGloin, J. M., Skokos, E. A., Duncan, P. W., Baker, D., Boult, C., Correa-De-Araujo, R. & Peduzzi, P., Jul 9 2020, In: New England Journal of Medicine. 383, 2, p. 129-140 12 p.

  Research output: Contribution to journal › Article › peer-review

  • Accidental Falls
  • Wounds and Injuries
  • Control Groups
  • Patient Outcome Assessment
  • Nurses
  8 Scopus citations

• Developing a screening tool for sarcopenia in hospitalized geriatric patients: Estimation of appendicular skeletal muscle mass using bioelectrical impedance

  Deer, R. R., Akhverdiyeva, L., Kuo, Y. F. & Volpi, E., Jul 2020, In: Clinical Nutrition. 39, 7, p. 2233-2237 5 p.

  Research output: Contribution to journal › Article › peer-review

  • Sarcopenia
  • Electric Impedance
  • Geriatrics
  • Skeletal Muscle
  • Photon Absorptiometry
  1 Scopus citations
• 2015

  Impact of combined resistance and aerobic exercise training on branched-chain amino acid turnover, glycine metabolism and insulin sensitivity in overweight humans

  Glynn, E. L., Piner, L. W., Huffman, K. M., Slentz, C. A., Elliot-Penry, L., AbouAssi, H., White, P. J., Bain, J. R., Muehlbauer, M. J., Ilkayeva, O. R., Stevens, R. D., Porter Starr, K. N., Bales, C. W., Volpi, E., Brosnan, M. J., Trimmer, J. K., Rolph, T. P., Newgard, C. B. & Kraus, W. E., Aug 9 2015, In: Diabetologia. 58, 10, p. 2324-2335 12 p.

  Research output: Contribution to journal › Article › peer-review

  • Branched Chain Amino Acids
  • Glycine
  • Overweight
  • Insulin Resistance
  • Exercise
  54 Scopus citations

• Age-related differences in lean mass, protein synthesis and skeletal muscle markers of proteolysis after bed rest and exercise rehabilitation

  Tanner, R. E., Brunker, L. B., Agergaard, J., Barrows, K. M., Briggs, R. A., Kwon, O. S., Young, L. M., Hopkins, P. N., Volpi, E., Marcus, R. L., Lastayo, P. C. & Drummond, M. J., Sep 1 2015, In: Journal of Physiology. 593, 18, p. 4259-4273 15 p.

  Research output: Contribution to journal › Article › peer-review

  • Bed Rest
  • Exercise Therapy
  • Proteolysis
  • Skeletal Muscle
  • Muscles
  83 Scopus citations

• Mitochondrial respiratory capacity and coupling control decline with age in human skeletal muscle

  Porter, C., Hurren, N. M., Cotter, M. V., Bhattarai, N., Reidy, P. T., Dillon, E., Durham, W. J., Tuvdendorj, D., Sheffield-Moore, M., Volpi, E., Sidossis, L. S., Rasmussen, B. & Børsheim, E., Aug 5 2015, In: American Journal of Physiology - Endocrinology and Metabolism. 309, 3, p. E224-E232

  Research output: Contribution to journal › Article › peer-review

  • Respiration
  • Skeletal Muscle
  • Adenosine Triphosphate
  • Oligomycins
  • Carbonyl Cyanide m-Chlorophenyl Hydrazone
  55 Scopus citations
• 2020

  Sex Hormones and Novel Corona Virus Infectious Disease (COVID-19)

  Al-Lami, R. A., Urban, R. J., Volpi, E., Algburi, A. M. A. & Baillargeon, J., Aug 2020, In: Mayo Clinic Proceedings. 95, 8, p. 1710-1714 5 p.

  Research output: Contribution to journal › Review article › peer-review

  Open Access

  • Coronavirus
  • Gonadal Steroid Hormones
  • Communicable Diseases
  • Virus Diseases
  • Testosterone
  9 Scopus citations
• 2013

  A soy, whey and caseinate blend extends postprandial skeletal muscle protein synthesis in rats

  Butteiger, D. N., Cope, M., Liu, P., Mukherjea, R., Volpi, E., Rasmussen, B. B. & Krul, E. S., Aug 2013, In: Clinical Nutrition. 32, 4, p. 585-591 7 p.

  Research output: Contribution to journal › Article › peer-review

  • Whey
  • Muscle Proteins
  • Whey Proteins
  • Meals
  • Skeletal Muscle
  15 Scopus citations

• Addition of carbohydrate or alanine to an essential amino acid mixture does not enhance human skeletal muscle protein anabolism^1-3

  Glynn, E. L., Fry, C. S., Timmerman, K. L., Drummond, M. J., Volpi, E. & Rasmussen, B. B., Mar 2013, In: Journal of Nutrition. 143, 3, p. 307-314 8 p.

  Research output: Contribution to journal › Article › peer-review

  • Essential Amino Acids
  • Muscle Proteins
  • Alanine
  • Carbohydrates
  • Skeletal Muscle
  32 Scopus citations
• 2014

  Soy-dairy protein blend and whey protein ingestion after resistance exercise increases amino acid transport and transporter expression in human skeletal muscle

  Reidy, P. T., Walker, D. K., Dickinson, J. M., Gundermann, D. M., Drummond, M. J., Timmerman, K. L., Cope, M. B., Mukherjea, R., Jennings, K., Volpi, E. & Rasmussen, B. B., Jun 1 2014, In: Journal of Applied Physiology. 116, 11, p. 1353-1364 12 p.

  Research output: Contribution to journal › Article › peer-review

  • Whey Proteins
  • Soybean Proteins
  • Amino Acid Transport Systems
  • Skeletal Muscle
  • Eating
  50 Scopus citations
• 2015

  Use of the short physical performance battery and step monitoring to evaluate improvements after epidural steroid injections in an elderly patient

  Przkora, R., Fisher, S. R., Von Der Hoeh, N., Heyde, C. E., Dominguez, J. D., Maybauer, M. O. & Volpi, E., Jun 1 2015, In: Journal of Clinical Gerontology and Geriatrics. 6, 2, p. 68-70 3 p., 139.

  Research output: Contribution to journal › Article › peer-review

  • Epidural Injections
  • Physical Functional Performance
  • Steroids
  • Elderly
  • Spinal Stenosis
  1 Scopus citations
• 2014

  Vitamin D and endothelial vasodilation in older individuals: Data from the PIVUS study

  Maggio, M., De Vita, F., Lauretani, F., Ceda, G. P., Volpi, E., Giallauria, F., De Cicco, G., Cattabiani, C., Melhus, H., Michaëlsson, K., Cederholm, T. & Lind, L., Sep 1 2014, In: Journal of Clinical Endocrinology and Metabolism. 99, 9, p. 3382-3389 8 p.

  Research output: Contribution to journal › Article › peer-review

  • Vasodilation
  • Vitamin D
  • Prospective Studies
  • Endothelium
  • Kidney Function Tests
  10 Scopus citations
• 2013

  Deficiency in Repair of the Mitochondrial Genome Sensitizes Proliferating Myoblasts to Oxidative Damage

  Szczesny, B., Olah, G., Walker, D. K., Volpi, E., Rasmussen, B. B., Szabo, C. & Mitra, S., Sep 16 2013, In: PloS one. 8, 9, e75201.

  Research output: Contribution to journal › Article › peer-review

  • Mitochondrial Genome
  • myoblasts
  • Myoblasts
  • mitochondrial genome
  • Muscle
  27 Scopus citations
• 2020

  AGS and NIA Bench-to Bedside Conference Summary: Osteoporosis and Soft Tissue (Muscle and Fat) Disorders

  Colón-Emeric, C., Whitson, H. E., Berry, S. D., Fielding, R. A., Houston, D. K., Kiel, D. P., Rosen, C. J., Seldeen, K. L., Volpi, E., White, J. P. & Troen, B. R., Jan 1 2020, In: Journal of the American Geriatrics Society. 68, 1, p. 31-38 8 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Muscular Diseases
  • Sarcopenia
  • Osteoporosis
  • Accidental Falls
  • Fats
  2 Scopus citations

• D-CARE: The Dementia Care Study: Design of a Pragmatic Trial of the Effectiveness and Cost Effectiveness of Health System–Based Versus Community-Based Dementia Care Versus Usual Dementia Care

  Reuben, D. B., Gill, T. M., Stevens, A., Williamson, J., Volpi, E., Lichtenstein, M., Jennings, L. A., Tan, Z., Evertson, L., Bass, D., Weitzman, L., Carnie, M., Wilson, N., Araujo, K., Charpentier, P., Meng, C., Greene, E. J., Dziura, J., Liu, J., Unger, E. & 15 others, Yang, M., Currie, K., Lenoir, K. M., Green, A. NR. S., Abraham, S., Vernon, A., Samper-Ternent, R., Raji, M., Hirst, R. M., Galloway, R., Finney, G. R., Ladd, I., Rahm, A. K., Borek, P. & Peduzzi, P., Nov 2020, In: Journal of the American Geriatrics Society. 68, 11, p. 2492-2499 8 p.

  Research output: Contribution to journal › Article › peer-review

  • Pragmatic Clinical Trials
  • Cost-Benefit Analysis
  • Dementia
  • Caregivers
  • Health
• 2013

  Short-term bed rest increases TLR4 and IL-6 expression in skeletal muscle of older adults

  Drummond, M. J., Timmerman, K. L., Markofski, M. M., Walker, D. K., Dickinson, J. M., Jamaluddin, M., Brasier, A. R., Rasmussen, B. B. & Volpi, E., Aug 1 2013, In: American Journal of Physiology - Regulatory Integrative and Comparative Physiology. 305, 3, p. R216-R223

  Research output: Contribution to journal › Article › peer-review

  • Bed Rest
  • Toll-Like Receptor 4
  • Skeletal Muscle
  • Interleukin-6
  • Cytokines
  59 Scopus citations
• 2020

  Resistance exercise training promotes fiber type-specific myonuclear adaptations in older adults

  Moro, T., Brightwell, C. R., Volpi, E., Rasmussen, B. B. & Fry, C., Jan 1 2020, In: Journal of Applied Physiology. 128, 4, p. 795-804 10 p.

  Research output: Contribution to journal › Article › peer-review

  • Resistance Training
  • Myosin Heavy Chains
  • Exercise
  • Skeletal Muscle Fibers
  • Lipids
  2 Scopus citations