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Author

  • Michael Sheetz
2011

Biophysics of substrate interaction: Influence on neural motility, differentiation, and repair

Moore, S. W. & Sheetz, M. P., Nov 2011, In : Developmental Neurobiology. 71, 11, p. 1090-1101 12 p.

Research output: Contribution to journalArticle

52 Scopus citations

Cellular mechanotransduction: Filamin A strains to regulate motility

Lynch, C. D. & Sheetz, M. P., Nov 22 2011, In : Current Biology. 21, 22, p. R916-R918

Research output: Contribution to journalShort survey

Open Access
6 Scopus citations

Controlled confinement of DNA at the nanoscale: nanofabrication and surface bio-functionalization.

Palma, M., Abramson, J. J., Gorodetsky, A. A., Nuckolls, C., Sheetz, M. P., Wind, S. J. & Hone, J., 2011, In : Methods in molecular biology (Clifton, N.J.). 749, p. 169-185 17 p.

Research output: Contribution to journalArticle

7 Scopus citations

Differential mechanical stability of filamin A rod segments

Chen, H., Zhu, X., Cong, P., Sheetz, M. P., Nakamura, F. & Yan, J., Sep 7 2011, In : Biophysical journal. 101, 5, p. 1231-1237 7 p.

Research output: Contribution to journalArticle

Open Access
34 Scopus citations
Open Access
128 Scopus citations

Filamin depletion blocks endoplasmic spreading and destabilizes force-bearing adhesions

Lynch, C. D., Gauthier, N. C., Biais, N., Lazar, A. M., Roca-Cusachs, P., Yu, C. H. & Sheetz, M. P., Apr 15 2011, In : Molecular Biology of the Cell. 22, 8, p. 1263-1273 11 p.

Research output: Contribution to journalArticle

43 Scopus citations

Mechanotransduction in vivo by repeated talin stretch-relaxation events depends upon vinculin

Margadant, F., Chew, L. L., Hu, X., Yu, H., Bate, N., Zhang, X. & Sheetz, M., Dec 2011, In : PLoS Biology. 9, 12, e1001223.

Research output: Contribution to journalArticle

Open Access
129 Scopus citations

Nanolithographic control of the spatial organization of cellular adhesion receptors at the single-molecule level

Schvartzman, M., Palma, M., Sable, J., Abramson, J., Hu, X., Sheetz, M. P. & Wind, S. J., Mar 9 2011, In : Nano Letters. 11, 3, p. 1306-1312 7 p.

Research output: Contribution to journalArticle

150 Scopus citations

New approach for measuring protrusive forces in cells

Mathur, A., Roca-Cusachs, P., Rossier, O. M., Wind, S. J., Sheetz, M. & Hone, J., Jan 1 2011, In : Journal of Vacuum Science and Technology B:Nanotechnology and Microelectronics. 29, 6, 06FA02.

Research output: Contribution to journalArticle

3 Scopus citations

Selective biomolecular nanoarrays for parallel single-molecule investigations

Palma, M., Abramson, J. J., Gorodetsky, A. A., Penzo, E., Gonzalez, R. L., Sheetz, M. P., Nuckolls, C., Hone, J. & Wind, S. J., May 25 2011, In : Journal of the American Chemical Society. 133, 20, p. 7656-7659 4 p.

Research output: Contribution to journalArticle

32 Scopus citations

Signaling network triggers and membrane physical properties control the actin cytoskeleton-driven isotropic phase of cell spreading

Rangamani, P., Fardin, M. A., Xiong, Y., Lipshtat, A., Rossier, O., Sheetz, M. P. & Iyengar, R., Feb 16 2011, In : Biophysical journal. 100, 4, p. 845-857 13 p.

Research output: Contribution to journalArticle

Open Access
22 Scopus citations

Temporary increase in plasma membrane tension coordinates the activation of exocytosis and contraction during cell spreading

Gauthier, N. C., Fardin, M. A., Roca-Cusachs, P. & Sheetz, M. P., Aug 30 2011, In : Proceedings of the National Academy of Sciences of the United States of America. 108, 35, p. 14467-14472 6 p.

Research output: Contribution to journalArticle

Open Access
180 Scopus citations
2012

Cell crawling mediates collective cell migration to close undamaged epithelial gaps

Anon, E., Serra-Picamal, X., Hersen, P., Gauthier, N. C., Sheetz, M. P., Trepat, X. & Ladoux, B., Jul 3 2012, In : Proceedings of the National Academy of Sciences of the United States of America. 109, 27, p. 10891-10896 6 p.

Research output: Contribution to journalArticle

Open Access
115 Scopus citations

Cells test substrate rigidity by local contractions on submicrometer pillars

Ghassemi, S., Meacci, G., Liu, S., Gondarenko, A. A., Mathur, A., Roca-Cusachs, P., Sheetz, M. P. & Hone, J., Apr 3 2012, In : Proceedings of the National Academy of Sciences of the United States of America. 109, 14, p. 5328-5333 6 p.

Research output: Contribution to journalArticle

Open Access
127 Scopus citations

Finding the weakest link-exploring integrin-mediated mechanical molecular pathways

Roca-Cusachs, P., Iskratsch, T. & Sheetz, M. P., Jul 1 2012, In : Journal of Cell Science. 125, 13, p. 3025-3038 14 p.

Research output: Contribution to journalComment/debate

Open Access
153 Scopus citations

Following nature’s challenges

Sheetz, M. P. & Kenan, W. R., Oct 2012, In : Nature Medicine. 18, 10, p. 1483-1485 3 p.

Research output: Contribution to journalArticle

Force-dependent cell signaling in stem cell differentiation

Yim, E. K. F. & Sheetz, M., Nov 6 2012, In : Stem Cell Research and Therapy. 3, 5, 41.

Research output: Contribution to journalReview article

Open Access
88 Scopus citations

Mechanical feedback between membrane tension and dynamics

Gauthier, N. C., Masters, T. A. & Sheetz, M., Oct 1 2012, In : Trends in Cell Biology. 22, 10, p. 527-535 9 p.

Research output: Contribution to journalReview article

219 Scopus citations

Microarray with micro- and nano-topographies enables identification of the optimal topography for directing the differentiation of primary murine neural progenitor cells

Moe, A. A. K., Suryana, M., Marcy, G., Lim, S. K., Ankam, S., Goh, J. Z. W., Jin, J., Teo, B. K. K., Law, J. B. K., Low, H. Y., Goh, E. L. K., Sheetz, M. P. & Yim, E. K. F., Oct 8 2012, In : Small. 8, 19, p. 3050-3061 12 p.

Research output: Contribution to journalArticle

78 Scopus citations

Modularity and functional plasticity of scaffold proteins as p(l)acemakers in cell signaling

Pan, C. Q., Sudol, M., Sheetz, M. & Low, B. C., Nov 1 2012, In : Cellular Signalling. 24, 11, p. 2143-2165 23 p.

Research output: Contribution to journalReview article

Open Access
49 Scopus citations

Netrin-1 Attracts axons through FAK-dependent mechanotransduction

Moore Dr., S. W., Zhang, X., Lynch, C. D. & Sheetz, M. P., Aug 22 2012, In : Journal of Neuroscience. 32, 34, p. 11574-11585 12 p.

Research output: Contribution to journalArticle

Open Access
51 Scopus citations

Second-generation covalent TMP-tag for live cell imaging

Chen, Z., Jing, C., Gallagher, S. S., Sheetz, M. P. & Cornish, V. W., Aug 22 2012, In : Journal of the American Chemical Society. 134, 33, p. 13692-13699 8 p.

Research output: Contribution to journalArticle

82 Scopus citations

Spatial-temporal reorganization of activated integrins

Yu, C. H., Luo, W. & Sheetz, M. P., 2012, In : Cell Adhesion and Migration. 6, 3, p. 280-284 5 p.

Research output: Contribution to journalReview article

Open Access
11 Scopus citations

The lasker awards: Motors take centre stage

Sheetz, M., Spudich, J. & Vale, R., Nov 1 2012, In : Nature Cell Biology. 14, 11, 1 p.

Research output: Contribution to journalEditorial

Open Access

The role of feature curvature in contact guidance

Mathur, A., Moore, S. W., Sheetz, M. & Hone, J., Jul 1 2012, In : Acta Biomaterialia. 8, 7, p. 2595-2601 7 p.

Research output: Contribution to journalArticle

34 Scopus citations

T lymphocyte myosin IIA is required for maturation of the immunological synapse

Kumari, S., Vardhana, S., Cammer, M., Curado, S., Santos, L., Sheetz, M. P. & Dustin, M. L., 2012, In : Frontiers in immunology. 3, AUG, Article 230.

Research output: Contribution to journalArticle

Open Access
49 Scopus citations
2013

Analysis of the local organization and dynamics of cellular actin networks

Luo, W., Yu, C. H., Lieu, Z. Z., Allard, J., Mogilner, A., Sheetz, M. P. & Bershadsky, A. D., 2013, In : Journal of Cell Biology. 202, 7, p. 1057-1073 17 p.

Research output: Contribution to journalArticle

Open Access
64 Scopus citations

Bifunctional nanoarrays for probing the immune response at the single-molecule level

Cai, H., Depoil, D., Palma, M., Sheetz, M. P., Dustin, M. L. & Wind, S. J., Nov 2013, In : Journal of Vacuum Science and Technology B: Microelectronics and Nanometer Structures. 31, 6, 6F902.

Research output: Contribution to journalArticle

12 Scopus citations

Endoplasmic spreading requires coalescence of vimentin intermediate filaments at force-bearing adhesions

Lynch, C. D., Lazar, A. M., Iskratsch, T., Zhang, X. & Sheetz, M. P., Jan 1 2013, In : Molecular Biology of the Cell. 24, 1, p. 21-30 10 p.

Research output: Contribution to journalArticle

Open Access
26 Scopus citations

FHOD1 is needed for directed forces and adhesion maturation during cell spreading and migration

Iskratsch, T., Yu, C. H., Mathur, A., Liu, S., Stévenin, V., Dwyer, J., Hone, J., Ehler, E. & Sheetz, M., Dec 9 2013, In : Developmental cell. 27, 5, p. 545-559 15 p.

Research output: Contribution to journalArticle

Open Access
61 Scopus citations

Heart extracellular matrix supports cardiomyocyte differentiation of mouse embryonic stem cells

Higuchi, S., Lin, Q., Wang, J., Lim, T. K., Joshi, S. B., Anand, G. S., Chung, M. C. M., Sheetz, M. P. & Fujita, H., Mar 2013, In : Journal of Bioscience and Bioengineering. 115, 3, p. 320-325 6 p.

Research output: Contribution to journalArticle

33 Scopus citations

Integrin-dependent force transmission to the extracellular matrix by α-actinin triggers adhesion maturation

Roca-Cusachs, P., Del Rio, A., Puklin-Faucher, E., Gauthier, N. C., Biais, N. & Sheetz, M. P., Apr 9 2013, In : Proceedings of the National Academy of Sciences of the United States of America. 110, 15, p. E1361-E1370

Research output: Contribution to journalArticle

Open Access
163 Scopus citations

Integrin-matrix clusters form podosome-like adhesions in the absence of traction forces

Yu, C. H., Rafiq, N. B. M., Krishnasamy, A., Hartman, K. L., Jones, G. E., Bershadsky, A. D. & Sheetz, M. P., Dec 12 2013, In : Cell Reports. 5, 5, p. 1456-1468 13 p.

Research output: Contribution to journalArticle

Open Access
90 Scopus citations

Mechanical perturbation of filamin A immunoglobulin repeats 20-21 reveals potential non-equilibrium mechanochemical partner binding function

Chen, H., Chandrasekar, S., Sheetz, M. P., Stossel, T. P., Nakamura, F. & Yan, J., Apr 10 2013, In : Scientific reports. 3, 1642.

Research output: Contribution to journalArticle

Open Access
29 Scopus citations

Myosin 1E localizes to actin polymerization sites in lamellipodia, affecting actin dynamics and adhesion formation

Gupta, P., Gauthier, N. C., Cheng-Han, Y., Zuanning, Y., Pontes, B., Ohmstede, M., Martin, R., Knölker, H. J., Döbereiner, H. G., Krendel, M. & Sheetz, M., 2013, In : Biology Open. 2, 12, p. 1-12 12 p.

Research output: Contribution to journalArticle

Open Access
17 Scopus citations

Substrate topography and size determine the fate of human embryonic stem cells to neuronal or glial lineage

Ankam, S., Suryana, M., Chan, L. Y., Moe, A. A. K., Teo, B. K. K., Law, J. B. K., Sheetz, M., Low, H. Y. & Yim, E. K. F., Jan 1 2013, In : Acta Biomaterialia. 9, 1, p. 4535-4545 11 p.

Research output: Contribution to journalArticle

100 Scopus citations

Toward a modular analysis of cell mechanosensing and mechanotransduction: A manual for cell mechanics

Dubin-Thaler, B. J. & Sheetz, M., Jan 1 2013, Cellular Mechanotransduction: Diverse Perspectives from Molecules to Tissues. Cambridge University Press, Vol. 9780521895231. p. 181-195 15 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

2014

Appreciating force and shape-the rise of mechanotransduction in cell biology

Iskratsch, T., Wolfenson, H. & Sheetz, M. P., Dec 11 2014, In : Nature Reviews Molecular Cell Biology. 15, 12, p. 825-833 9 p.

Research output: Contribution to journalReview article

299 Scopus citations

Can small institutes address some problems facing biomedical researchers?

Sheetz, M., Nov 1 2014, In : Molecular Biology of the Cell. 25, 21, p. 3267-3269 3 p.

Research output: Contribution to journalShort survey

2 Scopus citations

Early events in cell spreading as a model for quantitative analysis of biomechanical events

Wolfenson, H., Iskratsch, T. & Sheetz, M. P., Dec 2 2014, In : Biophysical journal. 107, 11, p. 2508-2514 7 p.

Research output: Contribution to journalReview article

Open Access
24 Scopus citations

Mechanical activation of vinculin binding to talin locks talin in an unfolded conformation

Yao, M., Goult, B. T., Chen, H., Cong, P., Sheetz, M. P. & Yan, J., Apr 9 2014, In : Scientific reports. 4, 4610.

Research output: Contribution to journalArticle

Open Access
155 Scopus citations

N-WASP-directed actin polymerization activates Cas phosphorylation and lamellipodium spreading

Zhang, X., Moore, S. W., Iskratsch, T. & Sheetz, M. P., Apr 2014, In : Journal of Cell Science. 127, 7, p. 1394-1405 12 p.

Research output: Contribution to journalArticle

Open Access
22 Scopus citations

Uncovering the mechanism of trapping and cell orientation during Neisseria gonorrhoeae twitching motility

Zaburdaev, V., Biais, N., Schmiedeberg, M., Eriksson, J., Jonsson, A. B., Sheetz, M. P. & Weitz, D. A., Oct 7 2014, In : Biophysical journal. 107, 7, p. 1523-1531 9 p.

Research output: Contribution to journalArticle

Open Access
28 Scopus citations

YAP/TAZ as mechanosensors and mechanotransducers in regulating organ size and tumor growth

Low, B. C., Pan, C. Q., Shivashankar, G. V., Bershadsky, A., Sudol, M. & Sheetz, M., Aug 19 2014, In : FEBS Letters. 588, 16, p. 2663-2670 8 p.

Research output: Contribution to journalReview article

Open Access
205 Scopus citations
2015

Cyclic stretching of soft substrates induces spreading and growth

Cui, Y., Hameed, F. M., Yang, B., Lee, K., Pan, C. Q., Park, S. & Sheetz, M., Feb 23 2015, In : Nature communications. 6, 6333.

Research output: Contribution to journalArticle

Open Access
115 Scopus citations

Integrin-beta3 clusters recruit clathrin-mediated endocytic machinery in the absence of traction force

Yu, C. H., Rafiq, N. B. M., Cao, F., Zhou, Y., Krishnasamy, A., Biswas, K. H., Ravasio, A., Chen, Z., Wang, Y. H., Kawauchi, K., Jones, G. E. & Sheetz, M. P., Oct 28 2015, In : Nature communications. 6, 8672.

Research output: Contribution to journalArticle

Open Access
39 Scopus citations

Mechanobiology

Shivashankar, G. V., Sheetz, M. & Matsudaira, P., Oct 1 2015, In : Integrative Biology (United Kingdom). 7, 10, p. 1091-1092 2 p.

Research output: Contribution to journalEditorial

5 Scopus citations

Micropatterning of TCR and LFA-1 ligands reveals complementary effects on cytoskeleton mechanics in T cells

Tabdanov, E., Gondarenko, S., Kumari, S., Liapis, A., Dustin, M. L., Sheetz, M. P., Kam, L. C. & Iskratsch, T., Oct 1 2015, In : Integrative Biology (United Kingdom). 7, 10, p. 1272-1284 13 p.

Research output: Contribution to journalArticle

Open Access
36 Scopus citations

Nascent Integrin Adhesions Form on All Matrix Rigidities after Integrin Activation

Changede, R., Xu, X., Margadant, F. & Sheetz, M. P., 2015, In : Developmental cell. 35, 5, p. 614-621 8 p.

Research output: Contribution to journalArticle

Open Access
53 Scopus citations

Parallel near-field photolithography with metal-coated elastomeric masks

Wu, J., Yu, C. H., Li, S., Zou, B., Liu, Y., Zhu, X., Guo, Y., Xu, H., Zhang, W., Zhang, L., Liu, B., Tian, D., Huang, W., Sheetz, M. & Huo, F., Jan 27 2015, In : Langmuir. 31, 3, p. 1210-1217 8 p.

Research output: Contribution to journalArticle

19 Scopus citations