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Author

  • Junji Iwahara
2011

Dynamics of lysine side-chain amino groups in a protein studied by heteronuclear 1H-15N NMR spectroscopy

Esadze, A., Li, D. W., Wang, T., Brüschweiler, R. & Iwahara, J., Feb 2 2011, In : Journal of the American Chemical Society. 133, 4, p. 909-919 11 p.

Research output: Contribution to journalArticle

59 Scopus citations

Signature of mobile hydrogen bonding of lysine side chains from long-range 15N-13C scalar J-couplings and computation

Zandarashvili, L., Li, D. W., Wang, T., Brüschweiler, R. & Iwahara, J., Jun 22 2011, In : Journal of the American Chemical Society. 133, 24, p. 9192-9195 4 p.

Research output: Contribution to journalArticle

29 Scopus citations
2012

Asymmetrical roles of zinc fingers in dynamic DNA-scanning process by the inducible transcription factor Egr-1

Zandarashvili, L., Vuzman, D., Esadze, A., Takayama, Y., Sahu, D., Levy, Y. & Iwahara, J., Jun 26 2012, In : Proceedings of the National Academy of Sciences of the United States of America. 109, 26, p. E1724-E1732

Research output: Contribution to journalArticle

73 Scopus citations
2013

Direct observation of the ion-pair dynamics at a protein-DNA interface by NMR spectroscopy

Anderson, K. M., Esadze, A., Manoharan, M., Brüschweiler, R., Gorenstein, D. G. & Iwahara, J., Mar 6 2013, In : Journal of the American Chemical Society. 135, 9, p. 3613-3619 7 p.

Research output: Contribution to journalArticle

49 Scopus citations

NMR studies on the dynamics of hydrogen bonds and ion pairs involving lysine side chains of proteins

Zandarashvili, L., Esadze, A. & Iwahara, J., 2013, Biomolecular Spectroscopy: Advances from Integrating Experiments and Theory. Academic Press Inc., p. 37-80 44 p. (Advances in Protein Chemistry and Structural Biology; vol. 93).

Research output: Chapter in Book/Report/Conference proceedingChapter

22 Scopus citations

Real-time kinetics of high-mobility group box 1 (HMGB1) oxidation in extracellular fluids studied by in situ protein NMR spectroscopy

Zandarashvili, L., Sahu, D., Lee, K., Lee, Y. S., Singh, P., Rajarathnam, K. & Iwahara, J., Apr 26 2013, In : Journal of Biological Chemistry. 288, 17, p. 11621-11627 7 p.

Research output: Contribution to journalArticle

35 Scopus citations

Speed-stability paradox in DNA-scanning by zinc-finger proteins

Iwahara, J. & Levy, Y., Jan 1 2013, In : Transcription. 4, 2, p. 58-61 4 p.

Research output: Contribution to journalArticle

Open Access
15 Scopus citations
2014
14 Scopus citations
49 Scopus citations

Stopped-flow fluorescence kinetic study of protein sliding and intersegment transfer in the target DNA search process

Esadze, A. & Iwahara, J., Jan 9 2014, In : Journal of Molecular Biology. 426, 1, p. 230-244 15 p.

Research output: Contribution to journalArticle

41 Scopus citations
2017

A unique and simple approach to improve sensitivity in 15N-NMR relaxation measurements for NH3+ groups: Application to a protein-DNA complex

Nguyen, D., Lokesh, G. L. R., Volk, D. E. & Iwahara, J., Aug 2017, In : Molecules. 22, 8, 1355.

Research output: Contribution to journalArticle

3 Scopus citations

Discrete-State Kinetics Model for NMR-Based Analysis of Protein Translocation on DNA at Equilibrium

Sahu, D. & Iwahara, J., Oct 19 2017, In : Journal of Physical Chemistry B. 121, 41, p. 9548-9556 9 p.

Research output: Contribution to journalArticle

3 Scopus citations

Internal Motions of Basic Side Chains of the Antennapedia Homeodomain in the Free and DNA-Bound States

Nguyen, D., Hoffpauir, Z. A. & Iwahara, J., Nov 7 2017, In : Biochemistry. 56, 44, p. 5866-5869 4 p.

Research output: Contribution to journalArticle

11 Scopus citations

Potential role of DNA methylation as a facilitator of target search processes for transcription factors through interplay with methyl-CpG-binding proteins

Kemme, C. A., Marquez, R., Luu, R. H. & Iwahara, J., Jul 1 2017, In : Nucleic acids research. 45, 13, p. 7751-7759 9 p.

Research output: Contribution to journalArticle

4 Scopus citations
2018

Direct detection of lysine side chain NH3+ in protein-heparin complexes using NMR spectroscopy

Sepuru, K. M., Iwahara, J. & Rajarathnam, K., Feb 7 2018, In : Analyst. 143, 3, p. 635-638 4 p.

Research output: Contribution to journalArticle

7 Scopus citations
2 Scopus citations

Lysines and Arginines play non-redundant roles in mediating chemokine-glycosaminoglycan interactions

Joseph, P. R. B., Sawant, K. V., Iwahara, J., Garofalo, R. P., Desai, U. R. & Rajarathnam, K., Dec 1 2018, In : Scientific reports. 8, 1, 12289.

Research output: Contribution to journalArticle

3 Scopus citations

NMR-based investigations into target DNA search processes of proteins

Iwahara, J., Zandarashvili, L., Kemme, C. A. & Esadze, A., Sep 15 2018, In : Methods. 148, p. 57-66 10 p.

Research output: Contribution to journalReview article

6 Scopus citations
3 Scopus citations
2019
1 Scopus citations

Mobility of Histidine Side Chains Analyzed with 15 N NMR Relaxation and Cross-Correlation Data: Insight into Zinc-Finger-DNA Interactions

Kemme, C. A., Luu, R. H., Chen, C., Pletka, C. C., Pettitt, B. M. & Iwahara, J., May 2 2019, In : Journal of Physical Chemistry B. 123, 17, p. 3706-3710 5 p.

Research output: Contribution to journalArticle

2020

Detecting Counterion Dynamics in DNA–Protein Association

Pletka, C. C., Nepravishta, R. & Iwahara, J., Jan 20 2020, In : Angewandte Chemie - International Edition. 59, 4, p. 1465-1468 4 p.

Research output: Contribution to journalArticle

2 Scopus citations

Dynamics of ionic interactions at protein-nucleic acid interfaces

Yu, B., Pettitt, B. M. & Iwahara, J., Sep 15 2020, In : Accounts of Chemical Research. 53, 9, p. 1802-1810 9 p.

Research output: Contribution to journalArticle

Open Access

Hydrogen-exchange kinetics studied through analysis of self-decoupling of nuclear magnetic resonance

Nepravishta, R., Yu, B. & Iwahara, J., Mar 2020, In : Journal of Magnetic Resonance. 312, 106687.

Research output: Contribution to journalArticle

NMR Observation of Intermolecular Hydrogen Bonds between Protein Tyrosine Side-Chain OH and DNA Phosphate Groups

Yu, B., Pletka, C. C. & Iwahara, J., Feb 13 2020, In : Journal of Physical Chemistry B. 124, 6, p. 1065-1070 6 p.

Research output: Contribution to journalArticle

2 Scopus citations

Racemic phosphorothioate as a tool for NMR investigations of protein-DNA complexes

Nepravishta, R., Pletka, C. C. & Iwahara, J., Sep 1 2020, In : Journal of Biomolecular NMR. 74, 8-9, p. 421-429 9 p.

Research output: Contribution to journalArticle