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• 2011

  Activity and the metabolic activation pathway of the potent and selective hepatitis C virus pronucleotide inhibitor PSI-353661

  Furman, P. A., Murakami, E., Niu, C., Lam, A. M., Espiritu, C., Bansal, S., Bao, H., Tolstykh, T., Micolochick Steuer, H., Keilman, M., Zennou, V., Bourne, N., Veselenak, R. L., Chang, W., Ross, B. S., Du, J., Otto, M. J. & Sofia, M. J., Aug 2011, In: Antiviral research. 91, 2, p. 120-132 13 p.

  Research output: Contribution to journal › Article › peer-review

  • 2-((5-(2-amino-6-methoxypurin-9-yl)-4-fluoro-3-hydroxy-4-methyltetrahydrofuran-2-ylmethoxy)phenoxyphosphorylamino)propionic acid isopropyl ester
  • Replicon
  • Metabolic Activation
  • Metabolic Networks and Pathways
  • Hepacivirus
  36 Scopus citations

• Enhancing the utility of a prM/E-expressing chimeric vaccine for Japanese encephalitis by addition of the JEV NS1 gene

  Ishikawa, T., Wang, G., Widman, D. G., Infante, E., Winkelmann, E. R., Bourne, N. & Mason, P. W., Oct 6 2011, In: Vaccine. 29, 43, p. 7444-7455 12 p.

  Research output: Contribution to journal › Article › peer-review

  • Japanese Encephalitis Vaccines
  • Japanese Encephalitis
  • encephalitis
  • vaccines
  • West Nile virus
  15 Scopus citations

• Inhibition of hepatitis C virus replicon RNA synthesis by PSI-352938, a cyclic phosphate prodrug of β-D-2′-deoxy-2′-α-fluoro- 2′-β-C-methylguanosine

  Lam, A. M., Espiritu, C., Murakami, E., Zennou, V., Bansal, S., Micolochick Steuer, H. M., Niu, C., Keilman, M., Bao, H., Bourne, N., Veselenak, R. L., Reddy, P. G., Chang, W., Du, J., Nagarathnam, D., Sofia, M. J., Otto, M. J. & Furman, P. A., Jun 2011, In: Antimicrobial agents and chemotherapy. 55, 6, p. 2566-2575 10 p.

  Research output: Contribution to journal › Article › peer-review

  • PSI 352938
  • 8-methylguanosine
  • Replicon
  • Prodrugs
  • Hepacivirus
  28 Scopus citations
• 2012

  A Vaxfectin^®-adjuvanted HSV-2 plasmid DNA vaccine is effective for prophylactic and therapeutic use in the guinea pig model of genital herpes

  Veselenak, R. L., Shlapobersky, M., Pyles, R. B., Wei, Q., Sullivan, S. M. & Bourne, N., Nov 19 2012, In: Vaccine. 30, 49, p. 7046-7051 6 p.

  Research output: Contribution to journal › Article › peer-review

  • vaxfectin
  • Herpes Genitalis
  • recombinant vaccines
  • DNA Vaccines
  • genitalia
  39 Scopus citations

• Bioluminescence methodology for the detection of protein-protein interactions within the voltage-gated sodium channel macromolecular complex

  Shavkunov, A., Panova, N., Prasai, A., Veselenak, R., Bourne, N., Stoilova-McPhie, S. & Laezza, F., Apr 1 2012, In: Assay and Drug Development Technologies. 10, 2, p. 148-160 13 p.

  Research output: Contribution to journal › Article › peer-review

  • fibroblast growth factor 14
  • Macromolecular Substances
  • Voltage-Gated Sodium Channels
  • Tail
  • Ion Channels
  31 Scopus citations

• Influence of methamphetamine on genital herpes simplex virus type 2 infection in a mouse model

  Valencia, F., Bubar, M. J., Milligan, G., Cunningham, K. A. & Bourne, N., Sep 2012, In: Sexually Transmitted Diseases. 39, 9, p. 720-725 6 p.

  Research output: Contribution to journal › Article › peer-review

  • Herpes Genitalis
  • Methamphetamine
  • Herpes Simplex
  • Cytokines
  • Sexually Transmitted Diseases
  10 Scopus citations

• Intrinsic adjuvanting of a novel single-cycle flavivirus vaccine in the absence of type I interferon receptor signaling

  Winkelmann, E. R., Widman, D. G., Xia, J., Ishikawa, T., Miller-Kittrell, M., Nelson, M. H., Bourne, N., Scholle, F., Mason, P. W. & Milligan, G. N., Feb 14 2012, In: Vaccine. 30, 8, p. 1465-1475 11 p.

  Research output: Contribution to journal › Article › peer-review

  • Interferon alpha-beta Receptor
  • Flavivirus
  • interferons
  • vaccines
  • Vaccines
  10 Scopus citations

• Quantitative assessment of microbicide-induced injury in the ovine vaginal epithelium using confocal microendoscopy

  Vargas, G., Patrikeev, I., Wei, J., Bell, B., Vincent, K., Bourne, N. & Motamedi, M., Feb 29 2012, In: BMC Infectious Diseases. 12, 48.

  Research output: Contribution to journal › Article › peer-review

  • Benzalkonium Compounds
  • Anti-Infective Agents
  • Sheep
  • Epithelium
  • Wounds and Injuries
  7 Scopus citations
• 2015

  A dengue virus type 4 model of disseminated lethal infection in AG129 mice

  Milligan, G. N., Sarathy, V. V., Infante, E., Li, L., Campbell, G. A., Beatty, P. R., Harris, E., Barrett, A. D. T. & Bourne, N., May 4 2015, In: PloS one. 10, 5, e0125476.

  Research output: Contribution to journal › Article › peer-review

  • Dengue virus
  • Dengue Virus
  • Viruses
  • dengue
  • Dengue
  33 Scopus citations

• A lethal murine infection model for dengue virus 3 in AG129 mice deficient in type I and II interferon receptors leads to systemic disease

  Sarathy, V. V., White, M., Li, L., Gorder, S. R., Pyles, R. B., Campbell, G. A., Milligan, G. N., Bourne, N. & Barrett, A. D. T., 2015, In: Journal of virology. 89, 2, p. 1254-1266 13 p.

  Research output: Contribution to journal › Article › peer-review

  • type II interferon receptor
  • Interferon alpha-beta Receptor
  • Dengue virus
  • Dengue Virus
  • interferons
  46 Scopus citations

• Characterization of lethal dengue virus type 4 (DENV-4) TVP-376 infection in mice lacking both IFN-α/β and IFN-γ receptors (AG129) and comparison with the DENV-2 AG129 mouse model

  Sarathy, V. V., Infante, E., Li, L., Campbell, G. A., Wang, T., Paessler, S., Beatty, P. R., Harris, E., Milligan, G. N., Bourne, N. & Barrett, A. D. T., Oct 2015, In: Journal of General Virology. 96, 10, p. 3035-3048 14 p.

  Research output: Contribution to journal › Article › peer-review

  • Dengue Virus
  • Dengue
  • Infection
  • Antiviral Agents
  • Vaccines
  17 Scopus citations

• Mouse models of dengue virus infection for vaccine testing

  Sarathy, V., Milligan, G., Bourne, N. & Barrett, A., Dec 10 2015, In: Vaccine. 33, 50, p. 7051-7060 10 p.

  Research output: Contribution to journal › Article › peer-review

  • Dengue virus
  • Dengue Virus
  • dengue
  • animal models
  • vaccines
  33 Scopus citations
• 2016

  An Infectious cDNA Clone of Zika Virus to Study Viral Virulence, Mosquito Transmission, and Antiviral Inhibitors

  Shan, C., Xie, X., Muruato, A. E., Rossi, S. L., Roundy, C. M., Azar, S. R., Yang, Y., Tesh, R. B., Bourne, N., Barrett, A. D., Vasilakis, N., Weaver, S. C. & Shi, P. Y., Jun 8 2016, In: Cell Host and Microbe. 19, 6, p. 891-900 10 p.

  Research output: Contribution to journal › Article › peer-review

  • Zika Virus
  • Culicidae
  • Virulence
  • Antiviral Agents
  • Complementary DNA
  162 Scopus citations

• Detection of herpes simplex virus type 2 (HSV-2) -specific cell-mediated immune responses in guinea pigs during latent HSV-2 genital infection

  Perry, C. L., Banasik, B. N., Gorder, S. R., Xia, J., Auclair, S., Bourne, N. & Milligan, G. N., Dec 1 2016, In: Journal of Immunological Methods. 439, p. 1-7 7 p.

  Research output: Contribution to journal › Article › peer-review

  • Herpes Genitalis
  • Guinea Pigs
  • Virus Latency
  • Infection
  • Enzyme-Linked Immunospot Assay
  2 Scopus citations

• In vivo rectal mucosal barrier function imaging in a large-animal model by using confocal endomicroscopy: Implications for injury assessment and use in HIV prevention studies

  Vargas, G., Vincent, K. L., Zhu, Y., Szafron, D., Brown, T. C., Villarreal, P. P., Bourne, N., Milligan, G. N. & Motamedib, M., Aug 2016, In: Antimicrobial agents and chemotherapy. 60, 8, p. 4600-4609 10 p.

  Research output: Contribution to journal › Article › peer-review

  • Animal Models
  • HIV
  • Wounds and Injuries
  • Mucous Membrane
  • Benzalkonium Compounds
  1 Scopus citations

• Topical injury evaluation of the murine colorectal mucosa using confocal endomicrosopy: a valuable method for assessing mucosal injuries associated with risk of pathogen transmission

  Vargas, G., Vincent, K. L., Wei, J., Bourne, N. & Motamedi, M., Nov 1 2016, In: Journal of Microscopy. 264, 2, p. 227-237 11 p.

  Research output: Contribution to journal › Article › peer-review

  • Infectious Disease Transmission
  • Mucous Membrane
  • Benzalkonium Compounds
  • Wounds and Injuries
  • Histology
  1 Scopus citations
• 2019

  An attenuated Zika virus NS4B protein mutant is a potent inducer of antiviral immune responses

  Li, G., Adam, A., Luo, H., Shan, C., Cao, Z., Fontes-Garfias, C. R., Sarathy, V. V., Teleki, C., Winkelmann, E. R., Liang, Y., Sun, J., Bourne, N., Barrett, A. D. T., Shi, P. Y. & Wang, T., Dec 1 2019, In: npj Vaccines. 4, 1, 48.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Zika Virus
  • Mutant Proteins
  • Antiviral Agents
  • Attenuated Vaccines
  • Flavivirus
  4 Scopus citations

• Attenuation of zika virus by passage in human HeLa cells

  Li, L., Collins, N. D., Widen, S. G., Davis, E. H., Kaiser, J. A., White, M. M., Greenberg, M. B., Barrett, A. D. T., Bourne, N. & Sarathy, V. V., Sep 2019, In: Vaccines. 7, 3, 93.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Zika Virus
  • HeLa Cells
  • Flavivirus
  • Culicidae
  • Viremia
  4 Scopus citations

• Cultivated human vaginal microbiome communities impact zika and herpes simplex virus replication in ex vivovaginal mucosal cultures

  Amerson-Brown, M. H., Miller, A. L., Maxwell, C. A., White, M. M., Vincent, K. L., Bourne, N. & Pyles, R. B., 2019, In: Frontiers in Microbiology. 10, JAN, 3340.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Simplexvirus
  • Microbiota
  • Virus Replication
  • Zika Virus
  • Epithelial Cells
  3 Scopus citations

• Development of an anti-guinea pig CD4 monoclonal antibody for depletion of CD4+ T cells in vivo

  Banasik, B. N., Perry, C. L., Keith, C. A., Bourne, N., Schäfer, H. & Milligan, G. N., Nov 2019, In: Journal of Immunological Methods. 474, 112654.

  Research output: Contribution to journal › Article › peer-review

  • Guinea Pigs
  • Monoclonal Antibodies
  • T-Lymphocytes
  • Active Immunotherapy
  • Investigational Therapies

• Development of disease and immunity at the genital epithelium following intrarectal inoculation of male guinea pigs with herpes simplex virus type 2

  Bourne, N., Banasik, B. N., Perry, C. L., Miller, A. L., White, M., Pyles, R. B. & Milligan, G. N., Jan 2 2019, In: Virology. 526, p. 180-188 9 p.

  Research output: Contribution to journal › Article › peer-review

  • Genitalia
  • Virus Shedding
  • Foreskin
  • Guinea Pigs
  • Perineum
  2 Scopus citations

• Increased frequency of virus shedding by herpes simplex virus 2-infected Guinea pigs in the absence of CD4 T lymphocytes

  Bourne, N., Perry, C. L., Banasik, B. N., Miller, A. L., White, M., Pyles, R. B., Schäfer, H. & Milligan, G. N., Feb 1 2019, In: Journal of virology. 93, 4, e0172118.

  Research output: Contribution to journal › Article › peer-review

  • Human herpesvirus 2
  • viral shedding
  • Virus Shedding
  • T-lymphocytes
  • Guinea Pigs
  6 Scopus citations