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• 2016

  Epidemiology, molecular biology, and pathogenic mechanisms of Ehrlichia infections

  Yu, X. J. & Walker, D., Jan 1 2016, Rickettsiales: Biology, Molecular Biology, Epidemiology, and Vaccine Development. Springer International Publishing, p. 225-240 16 p.

  Research output: Chapter in Book/Report/Conference proceeding › Chapter

  • Ehrlichia
  • Ehrlichiosis
  • Molecular Biology
  • Epidemiology
  • Pattern Recognition Receptors
  1 Scopus citations

• Fatal monocytic ehrlichiosis in woman, Mexico, 2013

  Sosa-Gutierrez, C. G., Solorzano-Santos, F., Walker, D. H., Torres, J., Serrano, C. A. & Gordillo-Perez, G., May 2016, In: Emerging infectious diseases. 22, 5, p. 871-874 4 p.

  Research output: Contribution to journal › Article › peer-review

  • Ehrlichiosis
  • Mexico
  • Ehrlichia chaffeensis
  • Fever
  • Tick Bites
  8 Scopus citations

• MyD88 mediates instructive signaling in dendritic cells and protective inflammatory response during rickettsial infection

  Bechelli, J., Smalley, C., Zhao, X., Judy, B., Valdes, P., Walker, D. H. & Fang, R., Apr 1 2016, In: Infection and immunity. 84, 4, p. 883-893 11 p.

  Research output: Contribution to journal › Article › peer-review

  • Dendritic Cells
  • Interleukin-1
  • Infection
  • Bone Marrow
  • Rickettsia
  12 Scopus citations

• Opossums and cat fleas: New insights in the ecology of murine typhus in Galveston, Texas

  Blanton, L. S., Idowu, B. M., Tatsch, T. N., Henderson, J. M., Bouyer, D. H. & Walker, D. H., Aug 2016, In: American Journal of Tropical Medicine and Hygiene. 95, 2, p. 457-461 5 p.

  Research output: Contribution to journal › Article › peer-review

  • Ctenocephalides
  • Endemic Flea-Borne Typhus
  • Siphonaptera
  • Opossums
  • Ecology
  32 Scopus citations

• Rickettsia

  Walker, D., Oct 6 2016, International Encyclopedia of Public Health. Elsevier Inc., p. 370-377 8 p.

  Research output: Chapter in Book/Report/Conference proceeding › Chapter

  • Coxiella
  • Rickettsia
  • Neorickettsia
  • Endemic Flea-Borne Typhus
  • Anaplasma
  2 Scopus citations

• Rickettsia australis activates inflammasome in human and murine macrophages

  Smalley, C., Bechelli, J., Rockx-Brouwer, D., Saito, T., Azar, S. R., Ismail, N., Walker, D. H. & Fang, R., Jun 2016, In: PloS one. 11, 6, e0157231.

  Research output: Contribution to journal › Article › peer-review

  • Rickettsia australis
  • inflammasomes
  • Macrophages
  • Rickettsia
  • Inflammasomes
  13 Scopus citations

• Scrub typhus - Scientific neglect, ever-widening impact

  Walker, D. H., Sep 8 2016, In: New England Journal of Medicine. 375, 10, p. 913-915 3 p.

  Research output: Contribution to journal › Short survey › peer-review
  32 Scopus citations

• Value of autopsy emphasized in the case report of a single patient with middle east respiratory syndrome

  Walker, D. H., Mar 1 2016, In: American Journal of Pathology. 186, 3, p. 507-510 4 p.

  Research output: Contribution to journal › Article › peer-review

  • Coronavirus Infections
  • Communicable Diseases
  • Autopsy
  7 Scopus citations
• 2017

  A review of the global epidemiology of scrub typhus

  Xu, G., Walker, D. H., Jupiter, D., Melby, P. C. & Arcari, C. M., Nov 3 2017, In: PLoS neglected tropical diseases. 11, 11, e0006062.

  Research output: Contribution to journal › Article › peer-review

  • Scrub Typhus
  • Epidemiology
  • Orientia tsutsugamushi
  • Public Health
  • Neglected Diseases
  74 Scopus citations

• CD8⁺T cells provide immune protection against murine disseminated endotheliotropic Orientia tsutsugamushi infection

  Xu, G., Mendell, N. L., Liang, Y., Shelite, T. R., Goez-Rivillas, Y., Soong, L., Bouyer, D. H. & Walker, D. H., Jul 19 2017, In: PLoS neglected tropical diseases. 11, 7, e0005763.

  Research output: Contribution to journal › Article › peer-review

  • Scrub Typhus
  • Orientia tsutsugamushi
  • T-Lymphocytes
  • Bacterial Load
  • Immunity
  15 Scopus citations

• Fibroblast growth factor receptor-1 mediates internalization of pathogenic spotted fever rickettsiae into host endothelium

  Sahni, A., Patel, J., Narra, H. P., Schroeder, C. L. C., Walker, D. H. & Sahni, S. K., Aug 2017, In: PloS one. 12, 8, e0183181.

  Research output: Contribution to journal › Article › peer-review

  • fibroblast growth factor receptor 1
  • Spotted Fever Group Rickettsiosis
  • Endothelial cells
  • Receptor, Fibroblast Growth Factor, Type 1
  • fibroblast growth factor receptors
  10 Scopus citations

• Flea-Borne Rickettsioses and Rickettsiae

  Blanton, L. S. & Walker, D. H., Jan 2017, In: American Journal of Tropical Medicine and Hygiene. 96, 1, p. 53-56 4 p.

  Research output: Contribution to journal › Review article › peer-review

  • Siphonaptera
  • Rickettsia felis
  • Rickettsia typhi
  • Ecology
  • Uncertainty
  33 Scopus citations

• Genotypic characterization of Orientia tsutsugamushi from patients in two geographical locations in Sri Lanka

  Premaratna, R., Blanton, L. S., Samaraweera, D. N., de Silva, G. N. N., Chandrasena, N. T. G. A., Walker, D. H. & de Silva, H. J., Jan 13 2017, In: BMC Infectious Diseases. 17, 1, 67.

  Research output: Contribution to journal › Article › peer-review

  • Orientia tsutsugamushi
  • Sri Lanka
  • Genotype
  • Real-Time Polymerase Chain Reaction
  • Fever
  9 Scopus citations

• Mechanisms of immunity to rickettsia and implications for vaccine development

  Walker, D., Jan 1 2017, In: Revista Colombiana de Ciencias Pecuarias. 30, p. 262-263 2 p.

  Research output: Contribution to journal › Article › peer-review

  • Spotted Fever Group Rickettsiosis
  • Rickettsia
  • vaccine development
  • fever
  • immunity

• Murine models of scrub typhus associated with host control of Orientia tsutsugamushi infection

  Mendell, N. L., Bouyer, D. H. & Walker, D. H., Mar 10 2017, In: PLoS neglected tropical diseases. 11, 3, e0005453.

  Research output: Contribution to journal › Article › peer-review

  • Scrub Typhus
  • Orientia tsutsugamushi
  • Infection
  • Trombiculidae
  • Heterologous Immunity
  11 Scopus citations

• Rickettsiae as Emerging Infectious Agents

  Fang, R., Blanton, L. S. & Walker, D. H., Jun 2017, In: Clinics in Laboratory Medicine. 37, 2, p. 383-400 18 p.

  Research output: Contribution to journal › Review article › peer-review

  • Arthropod Vectors
  • Epidemic Louse-Borne Typhus
  • Spotted Fever Group Rickettsiosis
  • Endothelial cells
  • Epidemiology
  25 Scopus citations

• Time to Worry about Anthrax Again

  Keim, P. S., Walker, D. H. & Zilinskas, R. A., Mar 14 2017, In: Scientific American. 316, 4, p. 70-75 6 p.

  Research output: Contribution to journal › Article › peer-review
  1 Scopus citations
• 2018

  A biosafety level-2 dose-dependent lethal mouse model of spotted fever rickettsiosis: Rickettsia parkeri Atlantic Rainforest-like isolate

  Londoño, A. F., Mendell, N. L., Walker, D. H. & Bouyer, D. H., Dec 5 2018, In: Unknown Journal.

  Research output: Contribution to journal › Article › peer-review

  • Containment of Biohazards
  • Rickettsia parkeri
  • Rainforest
  • Spotted Fever Group Rickettsiosis
  • Rickettsia

• Analysis of health-Care charges in murine typhus: Need for improved clinical recognition and diagnostics for acute disease

  Vohra, R. F., Walker, D. H. & Blanton, L. S., 2018, In: American Journal of Tropical Medicine and Hygiene. 98, 6, p. 1594-1598 5 p.

  Research output: Contribution to journal › Article › peer-review

  • Endemic Flea-Borne Typhus
  • Acute Disease
  • Delivery of Health Care
  • Human Influenza
  • Rickettsia typhi
  5 Scopus citations

• Chlamydial, Mycoplasmal, Rickettsial, and Ehrlichial Diseases

  Walker, D. H., 2018, Pulmonary Pathology: A Volume in the Series: Foundations in Diagnostic Pathology. Elsevier Inc., p. 315-326 12 p.

  Research output: Chapter in Book/Report/Conference proceeding › Chapter
• 2019

  A biosafety level-2 dose-dependent lethal mouse model of spotted fever rickettsiosis: Rickettsia parkeri atlantic rainforest strain

  Londoño, A. F., Mendell, N. L., Walker, D. H. & Bouyer, D. H., Jun 2019, In: PLoS neglected tropical diseases. 13, 6, e0007054.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Rainforest
  • Spotted Fever Group Rickettsiosis
  • Rickettsia
  • Containment of Biohazards
  • Infection
  2 Scopus citations

• A cluster of cases of rocky mountain spotted fever in an area of Colombia not known to be endemic for this disease

  Londoño, A. F., Arango-Ferreira, C., Acevedo-Gutiérrez, L. Y., Paternina, L. E., Montes, C., Ruiz, I., Labruna, M. B., Díaz, F. J., Walker, D. H. & Rodas, J. D., 2019, In: American Journal of Tropical Medicine and Hygiene. 101, 2, p. 336-342 7 p.

  Research output: Contribution to journal › Article › peer-review

  • Rocky Mountain Spotted Fever
  • Endemic Diseases
  • Colombia
  • Rickettsia rickettsii
  • Molecular Diagnostic Techniques
  2 Scopus citations

• Atg5 supports Rickettsia australis infection in macrophages in vitro and in vivo

  Bechelli, J., Vergara, L., Smalley, C., Buzhdygan, T. P., Bender, S., Zhang, W., Liu, Y., Popov, V. L., Wang, J., Garg, N., Hwang, S., Walker, D. H. & Fang, R., Jan 1 2019, In: Infection and immunity. 87, 1, e00651.

  Research output: Contribution to journal › Article › peer-review

  • Spotted Fever Group Rickettsiosis
  • Macrophages
  • In Vitro Techniques
  • Rickettsia
  • Interleukin-1
  9 Scopus citations

• Burkholderia pseudomallei ΔtonB Δhcp1 live attenuated vaccine strain elicits full protective immunity against aerosolized melioidosis infection

  Khakhum, N., Bharaj, P., Myers, J. N., Tapia, D., Kilgore, P. B., Ross, B. N., Walker, D. H., Endsley, J. J. & Torresa, A. G., Jan 1 2019, In: mSphere. 4, 1, e00570-18.

  Research output: Contribution to journal › Article › peer-review

  • Melioidosis
  • Burkholderia pseudomallei
  • Attenuated Vaccines
  • Burkholderia mallei
  • Immunity
  11 Scopus citations

• Ehrlichia chaffeensis outer membrane protein 1-specific human antibody-mediated immunity is defined by intracellular TRIM21-dependent innate immune activation and extracellular neutralization

  Velayutham, T. S., Kumar, S., Zhang, X., Kose, N., Walker, D. H., Winslow, G., Crowe, J. E. & McBride, J. W., Dec 1 2019, In: Infection and immunity. 87, 12, e00383-19.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Ehrlichia chaffeensis
  • Ehrlichia
  • Membrane Proteins
  • Immunity
  • Autophagy
  3 Scopus citations

• Evaluation of Burkholderia mallei ΔtonB Δhcp1 (CLH001) as a live attenuated vaccine in murine models of glanders and melioidosis

  Khakhum, N., Bharaj, P., Myers, J. N., Tapia, D., Walker, D. H., Endsley, J. J. & Torres, A. G., Jul 2019, In: PLoS neglected tropical diseases. 13, 7, e0007578.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Burkholderia mallei
  • Glanders
  • Melioidosis
  • Attenuated Vaccines
  • Humoral Immunity
  5 Scopus citations

• Pathogenesis of Rickettsial Diseases: Pathogenic and Immune Mechanisms of an Endotheliotropic Infection

  Sahni, A., Fang, R., Sahni, S. K. & Walker, D. H., 2019, In: Annual Review of Pathology: Mechanisms of Disease. 14, p. 127-152 26 p.

  Research output: Contribution to journal › Article › peer-review

  • Rickettsia Infections
  • Actins
  • Endothelial Cells
  • Infection
  • Rickettsia
  12 Scopus citations

• Rickettsiae Within the Fleas of Feral Cats in Galveston, Texas

  Blanton, L. S., Vohra, R. F., Fistein, L., Quade, B., Walker, D. H. & Bouyer, D. H., Sep 2019, In: Vector-Borne and Zoonotic Diseases. 19, 9, p. 647-651 5 p.

  Research output: Contribution to journal › Article › peer-review

  • Ctenocephalides
  • feral
  • Siphonaptera
  • Rickettsia typhi
  • Endemic Flea-Borne Typhus
  7 Scopus citations

• Seek and you shall find — Unknown pathogens?

  Vasilakis, N. & Walker, D. H., May 30 2019, In: New England Journal of Medicine. 380, 22, p. 2174-2175 2 p.

  Research output: Contribution to journal › Comment/debate › peer-review

• Sequelae of Lassa fever: Postviral cerebellar ataxia

  Ezeomah, C., Adoga, A., Ihekweazu, C., Paessler, S., Cisneros, I., Tomori, O. & Walker, D., Dec 1 2019, In: Open Forum Infectious Diseases. 6, 12

  Research output: Contribution to journal › Review article › peer-review

  Open Access

  • Lassa Fever
  • Cerebellar Ataxia
  • Ataxia
  • Antiviral Agents
  • Lassa virus
  1 Scopus citations

• Susceptibility of Rickettsia rickettsii to Tigecycline in a Cell Culture Assay and Animal Model for Rocky Mountain Spotted Fever

  Blanton, L. S., Wilson, N. M., Quade, B. R. & Walker, D. H., 2019, In: American Journal of Tropical Medicine and Hygiene. 101, 5, p. 1091-1095 5 p.

  Research output: Contribution to journal › Article › peer-review

  • Rickettsia rickettsii
  • Rocky Mountain Spotted Fever
  • Tigecycline
  • Cell Culture Techniques
  • Animal Models
  2 Scopus citations

• Vector Tick Transmission Model of Spotted Fever Rickettsiosis

  Saito, T. B., Bechelli, J., Smalley, C., Karim, S. & Walker, D. H., Jan 2019, In: American Journal of Pathology. 189, 1, p. 115-123 9 p.

  Research output: Contribution to journal › Article › peer-review

  • Spotted Fever Group Rickettsiosis
  • Ticks
  • Infection
  • Rickettsia Infections
  • Bacterial Load
  4 Scopus citations

• Whole-genome sequence of rickettsia parkeri strain atlantic rainforest, isolated from a colombian tick

  Londoño, A. F., Mendell, N. L., Valbuena, G. A., Routh, A. L., Wood, T. G., Widen, S. G., Rodas, J. D., Walker, D. H. & Bouyer, D. H., Sep 26 2019, In: Microbiology Resource Announcements. 8, 39, e00684-19.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Rainforest
  • Rickettsia
  • Ticks
  • Genome
  • Colombia
• 2020

  Activation of ASC Inflammasome Driven by Toll-Like Receptor 4 Contributes to Host Immunity against Rickettsial Infection

  Rumfield, C., Hyseni, I., McBride, J. W., Walker, D. H. & Fang, R., Mar 23 2020, In: Infection and immunity. 88, 4

  Research output: Contribution to journal › Article › peer-review

  • Inflammasomes
  • Toll-Like Receptor 4
  • Interleukin-1
  • Immunity
  • Macrophages

• A single mutation (V64G) within the ring domain of Z attenuates junin virus

  Hallam, S. J., Manning, J. T., Maruyama, J., Seregin, A., Huang, C., Walker, D. H., de la Torre, J. C. & Paessler, S., Sep 2020, In: PLoS neglected tropical diseases. 14, 9, p. 1-15 15 p., e0008555.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • New World Arenaviruses
  • Junin virus
  • Mutation
  • Arenaviridae
  • Fever

• Ehrlichia chaffeensis and E. canis hypothetical protein immunoanalysis reveals small secreted immunodominant proteins and conformation-dependent antibody epitopes

  Luo, T., Patel, J. G., Zhang, X., Walker, D. H. & McBride, J. W., Dec 1 2020, In: npj Vaccines. 5, 1, 85.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Ehrlichia chaffeensis
  • Protein Conformation
  • Epitopes
  • Antibodies
  • Proteins

• Human monocytic ehrlichiosis, Mexico City, Mexico

  Alcántara-Rodríguez, V. E., Sánchez-Montes, S., Contreras, H., Colunga-Salas, P., Fierro-Flores, L., Avalos, S., Rodríguez-Rangel, F., Becker, I. & Walker, D. H., Dec 2020, In: Emerging infectious diseases. 26, 12, p. 3016-3019 4 p.

  Research output: Contribution to journal › Article › peer-review

  • Ehrlichiosis
  • Mexico
  • Ehrlichia canis
  • Ehrlichia
  • Infection

• Human rickettsiosis caused by rickettsia parkeri strain Atlantic rainforest, Urabá, Colombia

  Arboleda, M., Acevedo-Gutiérrez, L. Y., Ávila, A., Ospina, D., Díaz, F. J., Walker, D. H. & Rodas, J. D., Dec 2020, In: Emerging infectious diseases. 26, 12, p. 3048-3050 3 p.

  Research output: Contribution to journal › Article › peer-review

  • Rainforest
  • Rickettsia
  • Colombia
  • vpr Genes
  • Gene Amplification

• Perspective Piece: Ideal Criteria for Accurate Mouse Models of Vector-Borne Diseases with Emphasis on Scrub Typhus and Dengue

  Sarathy, V. V. & Walker, D. H., Sep 2020, In: American Journal of Tropical Medicine and Hygiene. 103, 3, p. 970-975 6 p.

  Research output: Contribution to journal › Review article › peer-review

  • Scrub Typhus
  • Disease Vectors
  • Dengue
  • Orientia tsutsugamushi
  • Zoonoses

• Quantitative Proteomics of the Endothelial Secretome Identifies RC0497 as Diagnostic of Acute Rickettsial Spotted Fever Infections

  Zhao, Y., Fang, R., Zhang, J., Zhang, Y., Bechelli, J., Smalley, C., Valbuena, G., Walker, D. H., Oteo, J. A. & Brasier, A. R., Feb 2020, In: American Journal of Pathology. 190, 2, p. 306-322 17 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Spotted Fever Group Rickettsiosis
  • Rickettsia conorii
  • Proteomics
  • Boutonneuse Fever
  • Infection
  3 Scopus citations

• Recent research milestones in the pathogenesis of human rickettsioses and opportunities ahead

  Narra, H. P., Sahni, A., Walker, D. H. & Sahni, S. K., Jun 2020, In: Future Microbiology. 15, 9, p. 753-765 13 p.

  Research output: Contribution to journal › Review article › peer-review

  • Arthropod Vectors
  • resmethrin
  • Rickettsia
  • Antitoxins
  • Host-Pathogen Interactions
  1 Scopus citations

• The guinea pig model for tick-borne spotted fever rickettsioses: A second look

  Stokes, J. V., Walker, D. H. & Varela-Stokes, A. S., Nov 2020, In: Ticks and Tick-borne Diseases. 11, 6, 101538.

  Research output: Contribution to journal › Review article › peer-review

  Open Access

  • rickettsial diseases
  • Spotted Fever Group Rickettsiosis
  • Ticks
  • fever
  • ticks