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2012
Activation of Ras signaling pathway by 8-oxoguanine DNA glycosylase bound to its excision product, 8-oxoguanine
Boldogh, I., Hajas, G., Aguilera-Aguirre, L., Hegde, M. L., Radak, Z., Bacsi, A., Sur, S., Hazra, T. K. & Mitra, S., Jun 15 2012, In: Journal of Biological Chemistry. 287, 25, p. 20769-20773 5 p.Research output: Contribution to journal › Article › peer-review
85 Scopus citations -
Alternaria-induced release of IL-18 from damaged airway epithelial cells: An NF-κB dependent mechanism of Th2 differentiation?
Murai, H., Qi, H., Choudhury, B., Wild, J., Dharajiya, N., Vaidya, S., Kalita, A., Bacsi, A., Corry, D., Kurosky, A., Brasier, A., Boldogh, I. & Sur, S., Feb 7 2012, In: PloS one. 7, 2, e30280.Research output: Contribution to journal › Article › peer-review
22 Scopus citations -
Biochemical identification of a hydroperoxide derivative of the free 8-oxo-7,8-dihydroguanine base
Hajas, G., Bacsi, A., Aguilerra-Aguirre, L., German, P., Radak, Z., Sur, S., Hazra, T. K. & Boldogh, I., Feb 15 2012, In: Free Radical Biology and Medicine. 52, 4, p. 749-756 8 p.Research output: Contribution to journal › Article › peer-review
12 Scopus citations -
Enhancement of NEIL1 protein-initiated oxidized DNA base excision repair by heterogeneous nuclear ribonucleoprotein U (hnRNP-U) via direct interaction
Hegde, M. L., Banerjee, S., Hegde, P. M., Bellot, L. J., Hazra, T. K., Boldogh, I. & Mitra, S., Oct 5 2012, In: Journal of Biological Chemistry. 287, 41, p. 34202-34211 10 p.Research output: Contribution to journal › Article › peer-review
34 Scopus citations -
Human DNA glycosylase NEIL1's interactions with downstream repair proteins is critical for efficient repair of oxidized DNA base damage and enhanced cell survival
Hegde, M. L., Hegde, P. M., Arijit, D., Boldogh, I. & Mitra, S., Dec 2012, In: Biomolecules. 2, 4, p. 564-578 15 p.Research output: Contribution to journal › Article › peer-review
21 Scopus citations -
Hypolipidemic activity of eryngium carlinae on streptozotocin-induced diabetic rats
Noriega-Cisneros, R., Ortiz-Vila, O., Esquivel-Gutiérrez, E., Clemente-Guerrero, M., Manzo-Avalos, S., Salgado-Garciglia, R., Cortés-Rojo, C., Boldogh, I. & Saavedra-Molina, A., 2012, In: Biochemistry Research International. 603501.Research output: Contribution to journal › Article › peer-review
13 Scopus citations -
Increased risk of lung cancer associated with a functionally impaired polymorphic variant of the human DNA glycosylase NEIL2
Dey, S., Maiti, A. K., Hegde, M. L., Hegde, P. M., Boldogh, I., Sarkar, P. S., Abdel-Rahman, S. Z., Sarker, A. H., Hang, B., Xie, J., Tomkinson, A. E., Zhou, M., Shen, B., Wang, G., Wu, C., Yu, D., Lin, D., Cardenas, V. & Hazra, T. K., Jun 1 2012, In: DNA Repair. 11, 6, p. 570-578 9 p.Research output: Contribution to journal › Article › peer-review
26 Scopus citations -
Modulatory effects of low-dose hydrogen peroxide on the function of human plasmacytoid dendritic cells
Pazmandi, K., Magyarics, Z., Boldogh, I., Csillag, A., Rajnavolgyi, E. & Bacsi, A., Feb 1 2012, In: Free Radical Biology and Medicine. 52, 3, p. 635-645 11 p.Research output: Contribution to journal › Article › peer-review
5 Scopus citations -
Ragweed Subpollen Particles of Respirable Size Activate Human Dendritic Cells
Pazmandi, K., Kumar, B. V., Szabo, K., Boldogh, I., Szoor, A., Vereb, G., Veres, A., Lanyi, A., Rajnavolgyi, E. & Bacsi, A., Dec 14 2012, In: PloS one. 7, 12, e52085.Research output: Contribution to journal › Article › peer-review
17 Scopus citations -
Reactive oxygen species and allergic responses
Hosoki, K., Gandhe, R., Boldogh, I. & Sur, S., May 1 2012, Systems Biology of Free Radicals and Antioxidants. Springer-Verlag Berlin Heidelberg, p. 3239-3266 28 p.Research output: Chapter in Book/Report/Conference proceeding › Chapter
2 Scopus citations -
Role of human DNA glycosylase Nei-like 2 (NEIL2) and single strand break repair protein polynucleotide kinase 3′-phosphatase in maintenance of mitochondrial genome
Mandal, S. M., Hegde, M. L., Chatterjee, A., Hegde, P. M., Szczesny, B., Banerjee, D., Boldogh, I., Gao, R., Falkenberg, M., Gustafsson, C. M., Sarkar, P. S. & Hazra, T. K., Jan 20 2012, In: Journal of Biological Chemistry. 287, 4, p. 2819-2829 11 p.Research output: Contribution to journal › Article › peer-review
57 Scopus citations -
The effects of aging, physical training, and a single bout of exercise on mitochondrial protein expression in human skeletal muscle
Bori, Z., Zhao, Z., Koltai, E., Fatouros, I. G., Jamurtas, A. Z., Douroudos, I. I., Terzis, G., Chatzinikolaou, A., Sovatzidis, A., Draganidis, D., Boldogh, I. & Radak, Z., Jun 2012, In: Experimental Gerontology. 47, 6, p. 417-424 8 p.Research output: Contribution to journal › Article › peer-review
62 Scopus citations -
2013
8-Oxoguanine DNA glycosylase-1 links DNA repair to cellular signaling via the activation of the small GTPase Rac1
Hajas, G., Bacsi, A., Aguilera-Aguirre, L., Hegde, M. L., Tapas, K. H., Sur, S., Radak, Z., Ba, X. & Boldogh, I., 2013, In: Free Radical Biology and Medicine. 61, p. 384-394 11 p.Research output: Contribution to journal › Article › peer-review
58 Scopus citations -
Activation of cellular signaling by 8-oxoguanine DNA glycosylase-1-initiated DNA base excision repair
German, P., Szaniszlo, P., Hajas, G., Radak, Z., Bacsi, A., Hazra, T. K., Hegde, M. L., Ba, X. & Boldogh, I., Oct 2013, In: DNA Repair. 12, 10, p. 856-863 8 p.Research output: Contribution to journal › Article › peer-review
46 Scopus citations -
Aerobic endurance capacity affects spatial memory and SIRT1 is a potent modulator of 8-oxoguanine repair
Sarga, L., Hart, N., Koch, L. G., Britton, S. L., Hajas, G., Boldogh, I., Ba, X. & Radak, Z., Nov 12 2013, In: Neuroscience. 252, p. 326-336 11 p.Research output: Contribution to journal › Article › peer-review
18 Scopus citations -
Aldose Reductase Inhibition Prevents Allergic Airway Remodeling through PI3K/AKT/GSK3β Pathway in Mice
Yadav, U. C. S., Naura, A. S., Aguilera-Aguirre, L., Boldogh, I., Boulares, H. A., Calhoun, W. J., Ramana, K. V. & Srivastava, S. K., Feb 27 2013, In: PloS one. 8, 2, e57442.Research output: Contribution to journal › Article › peer-review
27 Scopus citations -
Down-regulation of 8-oxoguanine DNA glycosylase 1 expression in the airway epithelium ameliorates allergic lung inflammation
Bacsi, A., Aguilera-Aguirre, L., Szczesny, B., Radak, Z., Hazra, T. K., Sur, S., Ba, X. & Boldogh, I., Jan 1 2013, In: DNA Repair. 12, 1, p. 18-26 9 p.Research output: Contribution to journal › Article › peer-review
48 Scopus citations -
Mitochondrial response to oxidative and nitrosative stress in early stages of diabetes
Noriega-Cisneros, R., Cortés-Rojo, C., Manzo-Avalos, S., Clemente-Guerrero, M., Calderón-Cortés, E., Salgado-Garciglia, R., Montoya-Pérez, R., Boldogh, I. & Saavedra-Molina, A., Nov 2013, In: Mitochondrion. 13, 6, p. 835-840 6 p.Research output: Contribution to journal › Article › peer-review
17 Scopus citations -
Novel recombinant human lactoferrin: Differential activation of oxidative stress related gene expression
Kruzel, M. L., Actor, J. K., Zimecki, M., Wise, J., Płoszaj, P., Mirza, S., Kruzel, M., Hwang, S. A., Ba, X. & Boldogh, I., Dec 2013, In: Journal of Biotechnology. 168, 4, p. 666-675 10 p.Research output: Contribution to journal › Article › peer-review
27 Scopus citations -
Prereplicative repair of oxidized bases in the human genome is mediated by NEIL1 DNA glycosylase together with replication proteins
Hegde, M. L., Hegde, P. M., Bellot, L. J., Mandal, S. M., Hazra, T. K., Li, G. M., Boldogh, I., Tomkinson, A. E. & Mitra, S., Aug 13 2013, In: Proceedings of the National Academy of Sciences of the United States of America. 110, 33, p. E3090-E3099Research output: Contribution to journal › Article › peer-review
58 Scopus citations -
Redox-regulating sirtuins in aging, caloric restriction, and exercise
Radak, Z., Koltai, E., Taylor, A. W., Higuchi, M., Kumagai, S., Ohno, H., Goto, S. & Boldogh, I., May 2013, In: Free Radical Biology and Medicine. 58, p. 87-97 11 p.Research output: Contribution to journal › Review article › peer-review
67 Scopus citations -
Senescence of primary amniotic cells via oxidative DNA damage
Menon, R., Boldogh, I., Urrabaz-Garza, R., Polettini, J., Syed, T. A., Saade, G. R., Papaconstantinou, J. & Taylor, R. N., Dec 27 2013, In: PloS one. 8, 12, e83416.Research output: Contribution to journal › Article › peer-review
59 Scopus citations -
Systems approaches to modeling chronic mucosal inflammation
Kalita, M., Tian, B., Gao, B., Choudhary, S., Wood, T. G., Carmical, J. R., Boldogh, I., Mitra, S., Minna, J. D. & Brasier, A. R., Nov 18 2013, In: BioMed Research International. 2013, 505864.Research output: Contribution to journal › Article › peer-review
29 Scopus citations -
2014
8-Oxoguanine DNA glycosylase-1 augments proinflammatory gene expression by facilitating the recruitment of site-specific transcription factors
Ba, X., Bacsi, A., Luo, J., Aguilera-Aguirre, L., Zeng, X., Radak, Z., Brasier, A. R. & Boldogh, I., Mar 1 2014, In: Journal of Immunology. 192, 5, p. 2384-2394 11 p.Research output: Contribution to journal › Article › peer-review
54 Scopus citations -
8-Oxoguanine DNA glycosylase-1-mediated DNA repair is associated with Rho GTPase activation and α-smooth muscle actin polymerization
Luo, J., Hosoki, K., Bacsi, A., Radak, Z., Hegde, M. L., Sur, S., Hazra, T. K., Brasier, A. R., Ba, X. & Boldogh, I., Aug 2014, In: Free Radical Biology and Medicine. 73, p. 430-438 9 p.Research output: Contribution to journal › Article › peer-review
36 Scopus citations -
ATM regulates NF-κB-dependent immediate-early genes via RelA ser 276 phosphorylation coupled to CDK9 promoter recruitment
Fang, L., Choudhary, S., Zhao, Y., Edeh, C. B., Yang, C., Boldogh, I. & Brasier, A. R., 2014, In: Nucleic acids research. 42, 13, p. 8416-8432 17 p.Research output: Contribution to journal › Article › peer-review
32 Scopus citations -
Eating habits modulate short term memory and epigenetical regulation of brain derived neurotrophic factor in hippocampus of low- and high running capacity rats
Torma, F., Bori, Z., Koltai, E., Felszeghy, K., Vacz, G., Koch, L., Britton, S., Boldogh, I. & Radak, Z., Aug 2014, In: Brain Research Bulletin. 107, p. 54-60 7 p.Research output: Contribution to journal › Article › peer-review
2 Scopus citations -
Effects of diabetes on oxidative and nitrosative stress in kidney mitochondria from aged rats
Pérez-Gallardo, R. V., Noriega-Cisneros, R., Esquivel-Gutiérrez, E., Calderón-Cortés, E., Cortés-Rojo, C., Manzo-Avalos, S., Campos-García, J., Salgado-Garciglia, R., Montoya-Pérez, R., Boldogh, I. & Saavedra-Molina, A., Dec 9 2014, In: Journal of Bioenergetics and Biomembranes. 46, 6, p. 511-518 8 p.Research output: Contribution to journal › Article › peer-review
23 Scopus citations -
Exercise increases markers of spermatogenesis in rats selectively bred for low running capacity
Torma, F., Koltai, E., Nagy, E., Ziaaldini, M. M., Posa, A., Koch, L. G., Britton, S. L., Boldogh, I. & Radak, Z., Dec 10 2014, In: PloS one. 9, 12, e11407.Research output: Contribution to journal › Article › peer-review
13 Scopus citations -
Exposure to inhomogeneous static magnetic field beneficially affects allergic inflammation in a murine model
Csillag, A., Kumar, B. V., Szabó, K., Szilasi, M., Papp, Z., Szilasi, M. E., Pázmándi, K., Boldogh, I., Rajnavölgyi, É., Bácsi, A. & László, J. F., Jun 6 2014, In: Journal of the Royal Society Interface. 11, 95, 20140097.Research output: Contribution to journal › Article › peer-review
12 Scopus citations -
Expression of 8-oxoguanine Glycosylase in Human Fetal Membranes
Menon, R., Polettini, J., Syed, T. A., Saade, G. R. & Boldogh, I., Jan 1 2014, In: American Journal of Reproductive Immunology. 72, 1, p. 75-84 10 p.Research output: Contribution to journal › Article › peer-review
27 Scopus citations -
Histological evidence of oxidative stress and premature senescence in preterm premature rupture of the human fetal membranes recapitulated in vitro
Menon, R., Boldogh, I., Hawkins, H. K., Woodson, M., Polettini, J., Syed, T. A., Fortunato, S. J., Saade, G. R., Papaconstantinou, J. & Taylor, R. N., Jun 2014, In: American Journal of Pathology. 184, 6, p. 1740-1751 12 p.Research output: Contribution to journal › Article › peer-review
111 Scopus citations -
Innate inflammation induced by the 8-oxoguanine DNA glycosylase-1-KRAS-NF-κB pathway
Aguilera-Aguirre, L., Bacsi, A., Radak, Z., Hazra, T. K., Mitra, S., Sur, S., Brasier, A. R., Ba, X. & Boldogh, I., Nov 1 2014, In: Journal of Immunology. 193, 9, p. 4643-4653 11 p.Research output: Contribution to journal › Article › peer-review
60 Scopus citations -
NEIL2 Protects against Oxidative DNA damage induced by sidestream smoke in human cells
Sarker, A. H., Chatterjee, A., Williams, M., Lin, S., Havel, C., Jacob, P., Boldogh, I., Hazra, T. K., Talbot, P. & Hang, B., Mar 3 2014, In: PloS one. 9, 3, e90261.Research output: Contribution to journal › Article › peer-review
20 Scopus citations -
New perspectives on oxidized genome damage and repair inhibition by pro-oxidant metals in neurological diseases
Mitra, J., Guerrero, E. N., Hegde, P. M., Wang, H., Boldogh, I., Rao, K. S., Mitra, S. & Hegde, M. L., Sep 1 2014, In: Biomolecules. 4, 3, p. 678-703 26 p.Research output: Contribution to journal › Review article › peer-review
21 Scopus citations -
Oxidative modification enhances the immunostimulatory effects of extracellular mitochondrial DNA on plasmacytoid dendritic cells
Pazmandi, K., Agod, Z., Kumar, B. V., Szabo, A., Fekete, T., Sogor, V., Veres, A., Boldogh, I., Rajnavolgyi, E., Lanyi, A. & Bacsi, A., 2014, In: Free Radical Biology and Medicine. 77, p. 281-290 10 p.Research output: Contribution to journal › Article › peer-review
28 Scopus citations -
Systems biology approaches to understanding epithelial mesenchymal transition (EMT) in mucosal remodeling and signaling in asthma
Ijaz, T., Pazdrak, K., Kalita, M., Konig, R., Choudhary, S., Tian, B., Boldogh, I. & Brasier, A. R., Jun 2 2014, In: World Allergy Organization Journal. 7, 1, 13.Research output: Contribution to journal › Review article › peer-review
55 Scopus citations -
The redox-associated adaptive response of brain to physical exercise
Radak, Z., Ihasz, F., Koltai, E., Goto, S., Taylor, A. W. & Boldogh, I., Jan 1 2014, In: Free Radical Research. 48, 1, p. 84-92 9 p.Research output: Contribution to journal › Review article › peer-review
30 Scopus citations -
The role of 8-oxoguanine DNA glycosylase-1 in inflammation
Ba, X., Aguilera-Aguirre, L., Rashid, Q. T. A. N., Bacsi, A., Radak, Z., Sur, S., Hosoki, K., Hegde, M. L. & Boldogh, I., Sep 23 2014, In: International journal of molecular sciences. 15, 9, p. 16975-16997 23 p.Research output: Contribution to journal › Review article › peer-review
52 Scopus citations -
2015
17-beta estradiol inhibits oxidative stress-induced accumulation of AIF into nucleolus and PARP1-dependent cell death via estrogen receptor alpha
Batnasan, E., Wang, R., Wen, J., Ke, Y., Li, X., Bohio, A. A., Zeng, X., Huo, H., Han, L., Boldogh, I. & Ba, X., Jan 5 2015, In: Toxicology Letters. 232, 1, p. 1-9 9 p.Research output: Contribution to journal › Article › peer-review
14 Scopus citations -
8-Oxoguanine DNA glycosylase-1-driven DNA base excision repair: Role in asthma pathogenesis
Ba, X., Aguilera-Aguirre, L., Sur, S. & Boldogh, I., Feb 13 2015, In: Current opinion in allergy and clinical immunology. 15, 1, p. 89-97 9 p.Research output: Contribution to journal › Review article › peer-review
17 Scopus citations -
Analysis of a panel of 48 cytokines in BAL fluids specifically identifies IL-8 levels as the only cytokine that distinguishes controlled asthma from uncontrolled asthma, and correlates inversely with FEV1
Hosoki, K., Ying, S., Corrigan, C., Qi, H., Kurosky, A., Jennings, K., Sun, Q., Boldogh, I. & Sur, S., May 2015, In: PloS one. 10, 5, e0126035.Research output: Contribution to journal › Article › peer-review
47 Scopus citations -
Ataxia telangiectasia mutated kinase mediates NF-κB serine 276 phosphorylation and interferon expression via the IRF7-RIG-I amplification loop in paramyxovirus infection
Fang, L., Choudhary, S., Tian, B., Boldogh, I., Yang, C., Ivanciuc, T., Ma, Y., Garofalo, R. P. & Brasier, A. R., Jan 1 2015, In: Journal of virology. 89, 5, p. 2628-2642 15 p.Research output: Contribution to journal › Article › peer-review
20 Scopus citations -
BRG1 promotes the repair of DNA double-strand breaks by facilitating the replacement of RPA with RAD51
Qi, W., Wang, R., Chen, H., Wang, X., Xiao, T., Boldogh, I., Ba, X., Han, L. & Zeng, X., 2015, In: Journal of Cell Science. 128, 2, p. 317-330 14 p.Research output: Contribution to journal › Article › peer-review
45 Scopus citations -
Dynamic aberrant NF-κB spurs tumorigenesis: A new model encompassing the microenvironment
Vlahopoulos, S. A., Cen, O., Hengen, N., Agan, J., Moschovi, M., Critselis, E., Adamaki, M., Bacopoulou, F., Copland, J. A., Boldogh, I., Karin, M. & Chrousos, G. P., Aug 1 2015, In: Cytokine and Growth Factor Reviews. 26, 4, p. 389-403 15 p.Research output: Contribution to journal › Review article › peer-review
57 Scopus citations -
Exercise training increases anabolic and attenuates catabolic and apoptotic processes in aged skeletal muscle of male rats
Ziaaldini, M. M., Koltai, E., Csende, Z., Goto, S., Boldogh, I., Taylor, A. W. & Radak, Z., Jul 1 2015, In: Experimental Gerontology. 67, p. 9-14 6 p.Research output: Contribution to journal › Article › peer-review
43 Scopus citations -
Genetic Evidence for XPC-KRAS Interactions During Lung Cancer Development
Zhang, X., He, N., Gu, D., Wickliffe, J., Salazar, J., Boldogh, I. & Xie, J., Oct 20 2015, In: Journal of Genetics and Genomics. 42, 10, p. 589-596 8 p.Research output: Contribution to journal › Article › peer-review
4 Scopus citations -
Innate responses to pollen allergens
Hosoki, K., Boldogh, I. & Sur, S., Feb 13 2015, In: Current opinion in allergy and clinical immunology. 15, 1, p. 79-88 10 p.Research output: Contribution to journal › Review article › peer-review
17 Scopus citations -
Mitochondrial biogenesis-associated factors underlie the magnitude of response to aerobic endurance training in rats
Marton, O., Koltai, E., Takeda, M., Koch, L. G., Britton, S. L., Davies, K. J. A., Boldogh, I. & Radak, Z., Jan 1 2015, In: Pflugers Archiv European Journal of Physiology. 467, 4, p. 779-788 10 p.Research output: Contribution to journal › Article › peer-review
22 Scopus citations -
Neil2-null mice accumulate oxidized DNA bases in the transcriptionally active sequences of the genome and are susceptible to innate inflammation
Chakraborty, A., Wakamiya, M., Venkova-Canova, T., Pandita, R. K., Aguilera-Aguirre, L., Sarker, A. H., Singh, D. K., Hosoki, K., Wood, T. G., Sharma, G., Cardenas, V., Sarkar, P. S., Sur, S., Pandita, T. K., Boldogh, I. & Hazra, T. K., Oct 9 2015, In: Journal of Biological Chemistry. 290, 41, p. 24636-24648 13 p.Research output: Contribution to journal › Article › peer-review
35 Scopus citations