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• 2012

  Contribution of NK cells to the innate phase of host protection against an intracellular bacterium targeting systemic endothelium

  Fang, R., Ismail, N. & Walker, D. H., Jul 2012, In: American Journal of Pathology. 181, 1, p. 185-195 11 p.

  Research output: Contribution to journal › Article › peer-review

  • Natural Killer Cells
  • Endothelium
  • Bacteria
  • Rickettsia
  • Interferons
  21 Scopus citations

• Human ehrlichioses and rickettsioses in Cameroon

  Ndip, LN., Ndip, R., Walker, D. H. & McBride, J. W., 2012, Current Topics in Tropical Medicine. p. 25-42

  Research output: Chapter in Book/Report/Conference proceeding › Chapter

• Immune Mediators of protective and pathogenic immune responses in patients with mild and fatal human monocytotropic ehrlichiosis

  Ismail, N., Walker, D. H., Ghose, P. & Tang, Y. W., May 21 2012, In: BMC Immunology. 13, 26.

  Research output: Contribution to journal › Article › peer-review

  • Ehrlichiosis
  • Chemokines
  • Septic Shock
  • Interleukin-1
  • Interleukin-10
  11 Scopus citations

• Letters to the editor

  Walker, D., Mar 2012, In: Archives of Pathology and Laboratory Medicine. 136, 3, p. 235-236 2 p.

  Research output: Contribution to journal › Letter › peer-review

• New insight into immunity and immunopathology of Rickettsial diseases

  Mansueto, P., Vitale, G., Cascio, A., Seidita, A., Pepe, I., Carroccio, A., Di Rosa, S., Rini, G. B., Cillari, E. & Walker, D. H., 2012, In: Clinical and Developmental Immunology. 2012, 967852.

  Research output: Contribution to journal › Review article › peer-review

  • Rickettsia Infections
  • Rickettsia
  • Virulence
  • Immunity
  • Anaplasma
  83 Scopus citations

• Pathogenesis of lassa fever

  Yun, N. E. & Walker, D. H., Oct 2012, In: Viruses. 4, 10, p. 2031-2048 18 p.

  Research output: Contribution to journal › Review article › peer-review

  • Lassa Fever
  • Lassa virus
  • Old World Arenaviruses
  • Arenaviridae
  • Vaccines
  89 Scopus citations

• Person-to-person transmission of severe fever with thrombocytopenia syndrome virus

  Liu, Y., Li, Q., Hu, W., Wu, J., Weng, Y., Mei, L., Walker, D. H., Ren, J., Wang, Y. & Yu, X. J., Feb 1 2012, In: Vector-Borne and Zoonotic Diseases. 12, 2, p. 156-160 5 p.

  Research output: Contribution to journal › Article › peer-review

  • SFTS phlebovirus
  • Thrombocytopenia
  • Fever
  • Viruses
  • Phlebovirus
  154 Scopus citations

• Rickettsia, orientia, ehrlichia, anaplasma and coxiella: Typhus; spotted fevers; scrub typhus; ehrlichioses; Q fever

  Walker, D. & Yu, X. J., Jul 23 2012, Medical Microbiology: Eighteenth Edition. Elsevier Inc., p. 390-399 10 p.

  Research output: Chapter in Book/Report/Conference proceeding › Chapter
  1 Scopus citations

• Rocky mountain spotted fever and other rickettsioses

  Walker, D., May 15 2012, Schaechter's Mechanisms of Microbial Disease: Fifth Edition. Wolters Kluwer Health Adis (ESP), p. 301-307 7 p.

  Research output: Chapter in Book/Report/Conference proceeding › Chapter

• Systemic treatment with cpg-b after sublethal rickettsial infection induces mouse death through indoleamine 2,3-dioxygenase (ido)

  Xin, L., Shelite, T. R., Gong, B., Mendell, N. L., Soong, L., Fang, R. & Walker, D. H., Mar 28 2012, In: PloS one. 7, 3, e34062.

  Research output: Contribution to journal › Article › peer-review

  • indoleamine 2,3-dioxygenase
  • rickettsial diseases
  • T-cells
  • Indoleamine-Pyrrole 2,3,-Dioxygenase
  • Dendritic Cells
  16 Scopus citations
• 2013

  Approaches to vaccines against Orientia tsutsugamushi

  Valbuena, G. & Walker, D. H., 2013, In: Frontiers in cellular and infection microbiology. 4, JAN, Article 170.

  Research output: Contribution to journal › Article › peer-review

  • Orientia tsutsugamushi
  • Scrub Typhus
  • Vaccines
  • Pacific Ocean
  • Northern Asia

• Approaches to vaccines against Orientia tsutsugamushi

  Valbuena, G. & Walker, D. H., 2013, In: Frontiers in Cellular and Infection Microbiology. 4, JAN, Article 170.

  Research output: Contribution to journal › Review article › peer-review

  Open Access

  • Orientia tsutsugamushi
  • Scrub Typhus
  • Vaccines
  • Pacific Ocean
  • Northern Asia
  43 Scopus citations

• Case-Fatality ratio and effectiveness of ribavirin therapy among hospitalized patients in china who had severe fever with thrombocytopenia syndrome

  Liu, W., Lu, Q. B., Cui, N., Li, H., Wang, L. Y., Liu, K., Yang, Z. D., Wang, B. J., Wang, H. Y., Zhang, Y. Y., Zhuang, L., Hu, C. Y., Yuan, C., Fan, X. J., Wang, Z., Zhang, L., Zhang, X. A., Walker, D. H. & Cao, W. C., Nov 1 2013, In: Clinical Infectious Diseases. 57, 9, p. 1292-1299 8 p.

  Research output: Contribution to journal › Article › peer-review

  • Ribavirin
  • Thrombocytopenia
  • China
  • Fever
  • Fatal Outcome
  97 Scopus citations

• Compartmentalized, functional role of angiogenin during spotted fever group rickettsia-induced endothelial barrier dysfunction: Evidence of possible mediation by host tRNA-derived small noncoding RNAs

  Gong, B., Lee, Y. S., Lee, I., Shelite, T. R., Kunkeaw, N., Xu, G., Lee, K., Jeon, S. H., Johnson, B. H., Chang, Q., Ha, T., Mendell, N. L., Cheng, X., Bouyer, D. H., Boor, P. J., Ksiazek, T. G. & Walker, D. H., Jun 23 2013, In: BMC Infectious Diseases. 13, 1, 285.

  Research output: Contribution to journal › Article › peer-review

  • angiogenin
  • Spotted Fever Group Rickettsiosis
  • Rickettsia
  • Small Untranslated RNA
  • Transfer RNA
  27 Scopus citations

• Exchange protein directly activated by cAMP plays a critical role in bacterial invasion during fatal rickettsioses

  Gong, B., Shelite, T., Mei, F. C., Ha, T., Hu, Y., Xu, G., Chang, Q., Wakamiya, M., Ksiazek, T. G., Boor, P. J., Bouyer, D. H., Popov, V. L., Chen, J., Walker, D. H. & Cheng, X., Nov 26 2013, In: Proceedings of the National Academy of Sciences of the United States of America. 110, 48, p. 19615-19620 6 p.

  Research output: Contribution to journal › Article › peer-review

  • 3-(5-tert-butylisoxazol-3-yl)-2-((3-chlorophenyl)hydrazono)-3-oxopropionitrile
  • Spotted Fever Group Rickettsiosis
  • Bioterrorism
  • Bacterial Adhesion
  • Host-Pathogen Interactions
  48 Scopus citations

• Mice lacking functional STAT1 are highly susceptible to lethal infection with Lassa virus

  Yun, N. E., Seregin, A. V., Walker, D. H., Popov, V. L., Walker, A. G., Smith, J. N., Miller, M., de la Torre, J. C., Smith, J. K., Borisevich, V., Fair, J. N., Wauquier, N., Grant, D. S., Bockarie, B., Bente, D. & Paessler, S., 2013, In: Journal of virology. 87, 19, p. 10908-10911 4 p.

  Research output: Contribution to journal › Article › peer-review

  • Lassa virus fever
  • Lassa virus
  • Lassa Fever
  • Arenavirus
  • Western Africa
  33 Scopus citations

• Pathogenesis of the viral hemorrhagic fevers

  Paessler, S. & Walker, D. H., Jan 2013, In: Annual Review of Pathology: Mechanisms of Disease. 8, p. 411-440 30 p.

  Research output: Contribution to journal › Review article › peer-review

  • Viral Hemorrhagic Fevers
  • fever
  • pathogenesis
  • Marburg Virus Disease
  • Orthobunyavirus
  156 Scopus citations

• Recent molecular insights into rickettsial pathogenesis and immunity

  Sahni, S. K., Narra, H. P., Sahni, A. & Walker, D. H., Oct 2013, In: Future Microbiology. 8, 10, p. 1265-1288 24 p.

  Research output: Contribution to journal › Review article › peer-review

  • Arthropods
  • Rickettsia prowazekii
  • Immunity
  • Rickettsia Infections
  • Epidemic Louse-Borne Typhus
  59 Scopus citations

• Recombinant Ehrlichia P29 protein induces a protective immune response in a mouse model of ehrlichiosis

  Thirumalapura, N. R., Crocquet-Valdes, P. A., Saito, T. B., Thomas, S., McBride, J. W. & Walker, D. H., Dec 5 2013, In: Vaccine. 31, 50, p. 5960-5967 8 p.

  Research output: Contribution to journal › Article › peer-review

  • Ehrlichia
  • ehrlichiosis
  • Ehrlichiosis
  • Tandem Repeat Sequences
  • Ehrlichia chaffeensis
  4 Scopus citations

• Review article: Unresolved problems related to scrub typhus: A seriously neglected life-threatening disease

  Paris, D. H., Shelite, T. R., Day, N. P. & Walker, D. H., Aug 2013, In: American Journal of Tropical Medicine and Hygiene. 89, 2, p. 301-307 7 p.

  Research output: Contribution to journal › Review article › peer-review
  135 Scopus citations

• Rocky mountain spotted fever and other rickettsioses

  Walker, D., Jul 8 2013, Schaechter's Mechanisms of Microbial Disease: Fifth Edition. Wolters Kluwer Health Adis (ESP), p. 301-307 7 p.

  Research output: Chapter in Book/Report/Conference proceeding › Chapter

• Simple method to differentiate among Rickettsia species

  Peniche-Lara, G., Zavala-Velazquez, J., Dzul-Rosado, K., Walker, D. H. & Zavala-Castro, J., Apr 1 2013, In: Journal of Molecular Microbiology and Biotechnology. 23, 3, p. 203-208 6 p.

  Research output: Contribution to journal › Article › peer-review

  • Rickettsia
  • Polymerase Chain Reaction
  • Ecosystem
  • Enzymes
  • Restriction Fragment Length Polymorphisms
  8 Scopus citations

• Spotted fever group Rickettsia in small rodents from areas of low endemicity for Brazilian spotted fever in the Eastern Region of Minas Gerais State, Brazil

  Milagres, B. S., Padilha, A. F., Montandon, C. E., Freitas, R. N., Pacheco, R., Walker, D. H., Labruna, M. B., Mafra, C. L. & Galvão, M. A. M., May 2013, In: American Journal of Tropical Medicine and Hygiene. 88, 5, p. 937-939 3 p.

  Research output: Contribution to journal › Article › peer-review

  • Rocky Mountain Spotted Fever
  • Spotted Fever Group Rickettsiosis
  • Rickettsia
  • Brazil
  • Rodentia
  7 Scopus citations
• 2015

  An animal model of a newly emerging human ehrlichiosis

  Saito, T. B., Thirumalapura, N. R., Shelite, T. R., Rockx-Brouwer, D., Popov, V. L. & Walker, D. H., Feb 1 2015, In: Journal of Infectious Diseases. 211, 3, p. 452-461 10 p.

  Research output: Contribution to journal › Article › peer-review

  • Ehrlichia
  • Ehrlichiosis
  • Animal Models
  • Infection
  • Clinical Chemistry
  14 Scopus citations

• A Tick Vector Transmission Model of Monocytotropic Ehrlichiosis

  Saito, T. B. & Walker, D. H., Sep 15 2015, In: Journal of Infectious Diseases. 212, 6, p. 968-977 10 p.

  Research output: Contribution to journal › Article › peer-review

  • Ehrlichiosis
  • Ticks
  • Ehrlichia
  • Nymph
  • Larva
  14 Scopus citations

• Case report: An unusual cutaneous manifestation in a patient with murine typhus

  Blanton, L. S., Lea, A. S., Kelly, B. C. & Walker, D. H., Dec 2015, In: American Journal of Tropical Medicine and Hygiene. 93, 6, p. 1164-1167 4 p.

  Research output: Contribution to journal › Article › peer-review

  • Endemic Flea-Borne Typhus
  • Skin Manifestations
  • Rickettsia typhi
  • Siphonaptera
  • Mites
  9 Scopus citations

• Fever and rash after a safari

  Damavandy, A. A., Rojek, N. W., Dugan, E. M., Walker, D. & Norton, S. A., Jan 1 2015, In: Journal of the American Academy of Dermatology. 72, 1, p. e5-e6

  Research output: Contribution to journal › Article › peer-review

• Permissive and protective roles for neutrophils in leishmaniasis

  Carlsen, E. D., Liang, Y., Shelite, T. R., Walker, D. H., Melby, P. C. & Soong, L., Nov 2015, In: Clinical and Experimental Immunology. 182, 2, p. 109-18 10 p.

  Research output: Contribution to journal › Article › peer-review

  • Leishmaniasis
  • Parasites
  • Neutrophils
  • Leishmania
  • Infection
  32 Scopus citations

• Reemergence of murine typhus in galveston, texas, usa, 2013

  Blanton, L. S., Vohra, R. F., Bouyer, D. H. & Walker, D. H., 2015, In: Emerging infectious diseases. 21, 3, p. 484-486 3 p.

  Research output: Contribution to journal › Article › peer-review

  • Endemic Flea-Borne Typhus
  • Rickettsia typhi
  • Public Health
  • Physicians
  24 Scopus citations

• Rickettsia massiliae and rickettsia conorii israeli spotted fever strain differentially regulate endothelial cell responses

  Bechelli, J., Smalley, C., Milhano, N., Walker, D. H. & Fang, R., Sep 22 2015, In: PloS one. 10, 9, e0138830.

  Research output: Contribution to journal › Article › peer-review

  • Rickettsia massiliae
  • Rickettsia conorii
  • Spotted Fever Group Rickettsiosis
  • Endothelial cells
  • Rickettsia
  5 Scopus citations

• The role of CD8 T lymphocytes in rickettsial infections

  Walker, D. H. & Dumler, J. S., May 26 2015, In: Seminars in Immunopathology. 37, 3, p. 289-299 11 p.

  Research output: Contribution to journal › Review article › peer-review

  • T-Lymphocytes
  • Infection
  • Anaplasmosis
  • Ehrlichiosis
  • Immunity
  17 Scopus citations

• The role of Rhipicephalus sanguineus sensu lato saliva in the dissemination of Rickettsia conorii in C3H/HeJ mice

  Milhano, N., Saito, T. B., Bechelli, J., Fang, R., Vilhena, M., De Sousa, R. & Walker, D. H., Sep 1 2015, In: Medical and Veterinary Entomology. 29, 3, p. 225-229 5 p.

  Research output: Contribution to journal › Article › peer-review

  • Rickettsia conorii
  • Rhipicephalus sanguineus
  • tick
  • saliva
  • Ticks
  9 Scopus citations
• 2016

  An Intradermal Inoculation Mouse Model for Immunological Investigations of Acute Scrub Typhus and Persistent Infection

  Soong, L., Mendell, N. L., Olano, J. P., Rockx-Brouwer, D., Xu, G., Goez-Rivillas, Y., Drom, C., Shelite, T. R., Valbuena, G., Walker, D. H. & Bouyer, D. H., Aug 1 2016, In: PLoS neglected tropical diseases. 10, 8, e0004884.

  Research output: Contribution to journal › Article › peer-review

  • Immunological Models
  • Scrub Typhus
  • Infection
  • Orientia tsutsugamushi
  • Interleukin-9
  15 Scopus citations

• Editorial: Changing dynamics of human-rickettsial interactions

  Walker, D. H., Jan 2016, In: American Journal of Tropical Medicine and Hygiene. 94, 1, p. 3-4 2 p.

  Research output: Contribution to journal › Editorial › peer-review
  5 Scopus citations

• Ehrlichioses: An important one health opportunity

  Saito, T. B. & Walker, D. H., Sep 1 2016, In: Veterinary Sciences. 3, 3, 20.

  Research output: Contribution to journal › Review article › peer-review

  • ehrlichiosis
  • Ehrlichiosis
  • Ehrlichia
  • T-Lymphocytes
  • Health
  11 Scopus citations

• Endothelial Activation and Injury: The Mechanisms of Rickettsial Vasculiti

  Sahni, A., Narra, H. P., Walker, D. H. & Sahni, S. K., Jan 1 2016, Vascular Responses to Pathogens. Elsevier Inc., p. 111-122 12 p.

  Research output: Chapter in Book/Report/Conference proceeding › Chapter

  • Wounds and Injuries
  • Infection
  • Rickettsia Infections
  • Arthropod Vectors
  • Rickettsia
  5 Scopus citations

• Endothelial cell proteomic response to Rickettsia conorii infection reveals activation of the Janus Kinase (JAK)-signal transducer and activator of transcription (STAT)-inferferon stimulated gene (ISG)15 pathway and reprogramming plasma membrane integrin/cadherin signaling

  Zhao, Y., Valbuena, G., Walker, D. H., Gazi, M., Hidalgo, M., DeSousa, R., Oteo, J. A., Goez, Y. & Brasier, A. R., Jan 2016, In: Molecular and Cellular Proteomics. 15, 1, p. 289-304 16 p.

  Research output: Contribution to journal › Article › peer-review

  • Boutonneuse Fever
  • Endothelial cells
  • Cell membranes
  • Proteomics
  • Janus Kinases
  10 Scopus citations

• Epidemiology, molecular biology, and pathogenic mechanisms of Ehrlichia infections

  Yu, X. J. & Walker, D., Jan 1 2016, Rickettsiales: Biology, Molecular Biology, Epidemiology, and Vaccine Development. Springer International Publishing, p. 225-240 16 p.

  Research output: Chapter in Book/Report/Conference proceeding › Chapter

  • Ehrlichia
  • Ehrlichiosis
  • Molecular Biology
  • Epidemiology
  • Pattern Recognition Receptors
  1 Scopus citations

• Fatal monocytic ehrlichiosis in woman, Mexico, 2013

  Sosa-Gutierrez, C. G., Solorzano-Santos, F., Walker, D. H., Torres, J., Serrano, C. A. & Gordillo-Perez, G., May 2016, In: Emerging infectious diseases. 22, 5, p. 871-874 4 p.

  Research output: Contribution to journal › Article › peer-review

  • Ehrlichiosis
  • Mexico
  • Ehrlichia chaffeensis
  • Fever
  • Tick Bites
  8 Scopus citations

• MyD88 mediates instructive signaling in dendritic cells and protective inflammatory response during rickettsial infection

  Bechelli, J., Smalley, C., Zhao, X., Judy, B., Valdes, P., Walker, D. H. & Fang, R., Apr 1 2016, In: Infection and immunity. 84, 4, p. 883-893 11 p.

  Research output: Contribution to journal › Article › peer-review

  • Dendritic Cells
  • Interleukin-1
  • Infection
  • Bone Marrow
  • Rickettsia
  12 Scopus citations

• Opossums and cat fleas: New insights in the ecology of murine typhus in Galveston, Texas

  Blanton, L. S., Idowu, B. M., Tatsch, T. N., Henderson, J. M., Bouyer, D. H. & Walker, D. H., Aug 2016, In: American Journal of Tropical Medicine and Hygiene. 95, 2, p. 457-461 5 p.

  Research output: Contribution to journal › Article › peer-review

  • Ctenocephalides
  • Endemic Flea-Borne Typhus
  • Siphonaptera
  • Opossums
  • Ecology
  32 Scopus citations

• Rickettsia

  Walker, D., Oct 6 2016, International Encyclopedia of Public Health. Elsevier Inc., p. 370-377 8 p.

  Research output: Chapter in Book/Report/Conference proceeding › Chapter

  • Coxiella
  • Rickettsia
  • Neorickettsia
  • Endemic Flea-Borne Typhus
  • Anaplasma
  2 Scopus citations

• Rickettsia australis activates inflammasome in human and murine macrophages

  Smalley, C., Bechelli, J., Rockx-Brouwer, D., Saito, T., Azar, S. R., Ismail, N., Walker, D. H. & Fang, R., Jun 2016, In: PloS one. 11, 6, e0157231.

  Research output: Contribution to journal › Article › peer-review

  • Rickettsia australis
  • inflammasomes
  • Macrophages
  • Rickettsia
  • Inflammasomes
  13 Scopus citations

• Scrub typhus - Scientific neglect, ever-widening impact

  Walker, D. H., Sep 8 2016, In: New England Journal of Medicine. 375, 10, p. 913-915 3 p.

  Research output: Contribution to journal › Short survey › peer-review
  32 Scopus citations

• Value of autopsy emphasized in the case report of a single patient with middle east respiratory syndrome

  Walker, D. H., Mar 1 2016, In: American Journal of Pathology. 186, 3, p. 507-510 4 p.

  Research output: Contribution to journal › Article › peer-review

  • Coronavirus Infections
  • Communicable Diseases
  • Autopsy
  7 Scopus citations
• 2017

  A review of the global epidemiology of scrub typhus

  Xu, G., Walker, D. H., Jupiter, D., Melby, P. C. & Arcari, C. M., Nov 3 2017, In: PLoS neglected tropical diseases. 11, 11, e0006062.

  Research output: Contribution to journal › Article › peer-review

  • Scrub Typhus
  • Epidemiology
  • Orientia tsutsugamushi
  • Public Health
  • Neglected Diseases
  74 Scopus citations

• CD8⁺T cells provide immune protection against murine disseminated endotheliotropic Orientia tsutsugamushi infection

  Xu, G., Mendell, N. L., Liang, Y., Shelite, T. R., Goez-Rivillas, Y., Soong, L., Bouyer, D. H. & Walker, D. H., Jul 19 2017, In: PLoS neglected tropical diseases. 11, 7, e0005763.

  Research output: Contribution to journal › Article › peer-review

  • Scrub Typhus
  • Orientia tsutsugamushi
  • T-Lymphocytes
  • Bacterial Load
  • Immunity
  15 Scopus citations

• Fibroblast growth factor receptor-1 mediates internalization of pathogenic spotted fever rickettsiae into host endothelium

  Sahni, A., Patel, J., Narra, H. P., Schroeder, C. L. C., Walker, D. H. & Sahni, S. K., Aug 2017, In: PloS one. 12, 8, e0183181.

  Research output: Contribution to journal › Article › peer-review

  • fibroblast growth factor receptor 1
  • Spotted Fever Group Rickettsiosis
  • Endothelial cells
  • Receptor, Fibroblast Growth Factor, Type 1
  • fibroblast growth factor receptors
  10 Scopus citations

• Flea-Borne Rickettsioses and Rickettsiae

  Blanton, L. S. & Walker, D. H., Jan 2017, In: American Journal of Tropical Medicine and Hygiene. 96, 1, p. 53-56 4 p.

  Research output: Contribution to journal › Review article › peer-review

  • Siphonaptera
  • Rickettsia felis
  • Rickettsia typhi
  • Ecology
  • Uncertainty
  33 Scopus citations

• Genotypic characterization of Orientia tsutsugamushi from patients in two geographical locations in Sri Lanka

  Premaratna, R., Blanton, L. S., Samaraweera, D. N., de Silva, G. N. N., Chandrasena, N. T. G. A., Walker, D. H. & de Silva, H. J., Jan 13 2017, In: BMC Infectious Diseases. 17, 1, 67.

  Research output: Contribution to journal › Article › peer-review

  • Orientia tsutsugamushi
  • Sri Lanka
  • Genotype
  • Real-Time Polymerase Chain Reaction
  • Fever
  9 Scopus citations