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2012
Angiopoietin-2 enhances survival in experimental sepsis induced by multidrug-resistant Pseudomonas aeruginosa
Tzepi, I. M., Giamarellos-Bourboulis, E. J., Carrer, D. P., Tsaganos, T., Claus, R. A., Vaki, I., Pelekanou, A., Kotsaki, A., Tziortzioti, V., Topouzis, S., Bauer, M. & Papapetropoulos, A., Nov 1 2012, In: Journal of Pharmacology and Experimental Therapeutics. 343, 2, p. 278-287 10 p.Research output: Contribution to journal › Article › peer-review
16 Scopus citations -
A novel angiopoietin-derived peptide displays anti-angiogenic activity and inhibits tumour-induced and retinal neovascularization
Palmer, G. M., Tiran, Z., Zhou, Z. Z., Capozzi, M. E., Park, W., Coletta, C., Pyriochou, A., Kliger, Y., Levy, O., Borukhov, I., Dewhirst, M. W., Rotman, G., Penn, J. S. & Papapetropoulos, A., Mar 2012, In: British Journal of Pharmacology. 165, 6, p. 1891-1903 13 p.Research output: Contribution to journal › Article › peer-review
Open Access10 Scopus citations -
cGMP-Dependent Protein Kinase Contributes to Hydrogen Sulfide-Stimulated Vasorelaxation
Bucci, M., Papapetropoulos, A., Vellecco, V., Zhou, Z., Zaid, A., Giannogonas, P., Cantalupo, A., Dhayade, S., Karalis, K. P., Wang, R., Feil, R. & Cirino, G., Dec 28 2012, In: PloS one. 7, 12, e53319.Research output: Contribution to journal › Article › peer-review
Open Access90 Scopus citations -
Hydrogen sulfide and nitric oxide are mutually dependent in the regulation of angiogenesis and endothelium-dependent vasorelaxation
Coletta, C., Papapetropoulos, A., Erdelyi, K., Olah, G., Módis, K., Panopoulos, P., Asimakopoulou, A., Gerö, D., Sharina, I., Martin, E. & Szabo, C., Jun 5 2012, In: Proceedings of the National Academy of Sciences of the United States of America. 109, 23, p. 9161-9166 6 p.Research output: Contribution to journal › Article › peer-review
390 Scopus citations -
Nitric oxide regulates cytokine induction in the diaphragm in response to inspiratory resistive breathing
Sigala, I., Zacharatos, P., Boulia, S., Toumpanakis, D., Michailidou, T., Parthenis, D., Roussos, C., Papapetropoulos, A., Hussain, S. N. & Vassilakopoulos, T., Nov 15 2012, In: Journal of Applied Physiology. 113, 10, p. 1594-1603 10 p.Research output: Contribution to journal › Article › peer-review
16 Scopus citations -
Short-term statin administration in hypercholesterolaemic rabbits resistant to postconditioning: Effects on infarct size, endothelial nitric oxide synthase, and nitro-oxidative stress
Andreadou, I., Farmakis, D., Prokovas, E., Sigala, F., Zoga, A., Spyridaki, K., Papalois, A., Papapetropoulos, A., Anastasiou-Nana, M., Kremastinos, D. T. & Iliodromitis, E. K., Jun 1 2012, In: Cardiovascular research. 94, 3, p. 501-509 9 p.Research output: Contribution to journal › Article › peer-review
49 Scopus citations -
Soluble guanylyl cyclase is a target of angiotensin II-induced nitrosative stress in a hypertensive rat model
Crassous, P. A., Couloubaly, S., Huang, C., Zhou, Z., Baskaran, P., Kim, D. D., Papapetropoulos, A., Fioramonti, X., Durán, W. N. & Beuve, A., Sep 1 2012, In: American Journal of Physiology - Heart and Circulatory Physiology. 303, 5, p. H597-H604Research output: Contribution to journal › Article › peer-review
29 Scopus citations -
Thioglycine and l-thiovaline: Biologically active H 2S-donors
Zhou, Z., Von Wantoch Rekowski, M., Coletta, C., Szabo, C., Bucci, M., Cirino, G., Topouzis, S., Papapetropoulos, A. & Giannis, A., Apr 15 2012, In: Bioorganic and Medicinal Chemistry. 20, 8, p. 2675-2678 4 p.Research output: Contribution to journal › Article › peer-review
44 Scopus citations -
2014
Effect of S-adenosyl-L-methionine (SAM), an allosteric activator of cystathionine-β-synthase (CBS) on colorectal cancer cell proliferation and bioenergetics in vitro
Módis, K., Coletta, C., Asimakopoulou, A., Szczesny, B., Chao, C., Papapetropoulos, A., Hellmich, M. R. & Szabo, C., Sep 15 2014, In: Nitric Oxide - Biology and Chemistry. 41, p. 146-156 11 p.Research output: Contribution to journal › Article › peer-review
50 Scopus citations -
Hydrogen sulfide accounts for the peripheral vascular effects of zofenopril independently of ACE inhibition
Bucci, M., Vellecco, V., Cantalupo, A., Brancaleone, V., Zhou, Z., Evangelista, S., Calderone, V., Papapetropoulos, A. & Cirino, G., Jan 1 2014, In: Cardiovascular research. 102, 1, p. 138-147 10 p.Research output: Contribution to journal › Article › peer-review
Open Access53 Scopus citations -
Modulation of poly(ADP-Ribose) polymerase-1 (PARP-1)-mediated oxidative cell injury by ring finger protein 146 (RNF146) in cardiac myocytes
Gerö, D., Szoleczky, P., Chatzianastasiou, A., Papapetropoulos, A. & Szabo, C., 2014, In: Molecular Medicine. 20, 1, p. 313-328 16 p.Research output: Contribution to journal › Article › peer-review
20 Scopus citations -
Nitric oxide and heat shock protein 90 activate soluble guanylate cyclase by driving rapid change in its subunit interactions and heme content
Ghosh, A., Stasch, J. P., Papapetropoulos, A. & Stuehr, D. J., May 30 2014, In: Journal of Biological Chemistry. 289, 22, p. 15259-15271 13 p.Research output: Contribution to journal › Article › peer-review
Open Access32 Scopus citations -
Regulation of mitochondrial bioenergetic function by hydrogen sulfide. Part II Pathophysiological and therapeutic aspects
Módis, K., Bos, E. M., Calzia, E., Van Goor, H., Coletta, C., Papapetropoulos, A., Hellmich, M. R., Radermacher, P., Bouillaud, F. & Szabo, C., Apr 2014, In: British Journal of Pharmacology. 171, 8, p. 2123-2146 24 p.Research output: Contribution to journal › Review article › peer-review
80 Scopus citations -
2015
ATP-sensitive potassium channel activation induces angiogenesis in vitro and in vivo
Umaru, B., Pyriochou, A., Kotsikoris, V., Papapetropoulos, A. & Topouzis, S., Jul 1 2015, In: Journal of Pharmacology and Experimental Therapeutics. 354, 1, p. 79-87 9 p.Research output: Contribution to journal › Article › peer-review
14 Scopus citations -
Cardioprotection by H2S engages a cGMP-dependent protein kinase G/phospholamban pathway
Bibli, S. I., Andreadou, I., Chatzianastasiou, A., Tzimas, C., Sanoudou, D., Kranias, E., Brouckaert, P., Coletta, C., Szabo, C., Kremastinos, D. T., Iliodromitis, E. K. & Papapetropoulos, A., Jun 1 2015, In: Cardiovascular research. 106, 3, p. 432-442 11 p.Research output: Contribution to journal › Article › peer-review
52 Scopus citations -
Extending the translational potential of targeting NO/cGMP-regulated pathways in the CVS
Papapetropoulos, A., Hobbs, A. J. & Topouzis, S., Mar 2015, In: British Journal of Pharmacology. 172, 6, p. 1397-1414 18 p.Research output: Contribution to journal › Review article › peer-review
Open Access19 Scopus citations -
Guanylyl cyclase activation reverses resistive breathing-induced lung injury and inflammation
Glynos, C., Toumpanakis, D., Loverdos, K., Karavana, V., Zhou, Z., Magkou, C., Dettoraki, M., Perlikos, F., Pavlidou, A., Kotsikoris, V., Topouzis, S., Theocharis, S. E., Brouckaert, P., Giannis, A., Papapetropoulos, A. & Vassilakopoulos, T., Jun 1 2015, In: American journal of respiratory cell and molecular biology. 52, 6, p. 762-771 10 p.Research output: Contribution to journal › Article › peer-review
14 Scopus citations -
Hydrogen sulfide and PKG in ischemia–reperfusion injury: sources, signaling, accelerators and brakes
Andreadou, I., Iliodromitis, E. K., Szabo, C. & Papapetropoulos, A., Sep 1 2015, In: Basic Research in Cardiology. 110, 5, 52.Research output: Contribution to journal › Editorial › peer-review
12 Scopus citations -
Pharmacological tools for hydrogen sulphide research: A brief, introductory guide for beginners
Papapetropoulos, A., Whiteman, M. & Cirino, G., Mar 2015, In: British Journal of Pharmacology. 172, 6, p. 1633-1637 5 p.Research output: Contribution to journal › Review article › peer-review
52 Scopus citations -
Pharmacology of the 'gasotransmitters' NO, CO and H 2 S: Translational opportunities
Papapetropoulos, A., Foresti, R. & Ferdinandy, P., Jan 1 2015, In: British Journal of Pharmacology. 172, 6, p. 1395-1396 2 p.Research output: Contribution to journal › Editorial › peer-review
22 Scopus citations -
Phosphinodithioate and phosphoramidodithioate hydrogen sulfide donors
Whiteman, M., Perry, A., Zhou, Z., Bucci, M., Papapetropoulos, A., Cirino, G. & Wood, M. E., 2015, In: Handbook of Experimental Pharmacology. 230, p. 337-363 27 p.Research output: Contribution to journal › Article › peer-review
38 Scopus citations -
Regulation of vascular tone, angiogenesis and cellular bioenergetics by the 3-mercaptopyruvate sulfurtransferase/H2S pathway: Functional impairment by hyperglycemia and restoration by dl-α-lipoic acid
Coletta, C., Módis, K., Szczesny, B., Brunyánszki, A., Oláh, G., Rios, E. C. S., Yanagi, K., Ahmad, A., Papapetropoulos, A. & Szabo, C., Feb 18 2015, In: Molecular Medicine. 21, p. 1-14 14 p.Research output: Contribution to journal › Article › peer-review
69 Scopus citations -
Role of cGMP in hydrogen sulfide signaling
Bibli, S. I., Yang, G., Zhou, Z., Wang, R., Topouzis, S. & Papapetropoulos, A., Apr 30 2015, In: Nitric Oxide - Biology and Chemistry. 46, p. 7-13 7 p.Research output: Contribution to journal › Review article › peer-review
27 Scopus citations -
Role of the cystathionine γ lyase/hydrogen sulfide pathway in human melanoma progression
Panza, E., De Cicco, P., Armogida, C., Scognamiglio, G., Gigantino, V., Botti, G., Germano, D., Napolitano, M., Papapetropoulos, A., Bucci, M., Cirino, G. & Ianaro, A., Jan 1 2015, In: Pigment Cell and Melanoma Research. 28, 1, p. 61-72 12 p.Research output: Contribution to journal › Article › peer-review
57 Scopus citations -
The role of gasotransmitters NO, H2S and CO in myocardial ischaemia/reperfusion injury and cardioprotection by preconditioning, postconditioning and remote conditioning
Andreadou, I., Iliodromitis, E. K., Rassaf, T., Schulz, R., Papapetropoulos, A. & Ferdinandy, P., Jan 1 2015, In: British Journal of Pharmacology. 172, 6, p. 1587-1606 20 p.Research output: Contribution to journal › Review article › peer-review
122 Scopus citations -
The role of H2S bioavailability in endothelial dysfunction
Wang, R., Szabo, C., Ichinose, F., Ahmed, A., Whiteman, M. & Papapetropoulos, A., Sep 12 2015, In: Trends in Pharmacological Sciences. 36, 9, p. 568-578 11 p.Research output: Contribution to journal › Review article › peer-review
81 Scopus citations -
Welcome note
Papapetropoulos, A., May 1 2015, In: Nitric Oxide - Biology and Chemistry. 47, S, 1 p.Research output: Contribution to journal › Editorial › peer-review
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2016
1H, 13C, 15N backbone and side-chain resonance assignment of Nostoc sp. C139A variant of the heme–nitric oxide/oxygen binding (H-NOX) domain
Alexandropoulos, I. I., Argyriou, A. I., Marousis, K. D., Topouzis, S., Papapetropoulos, A. & Spyroulias, G. A., Oct 1 2016, In: Biomolecular NMR Assignments. 10, 2, p. 395-400 6 p.Research output: Contribution to journal › Article › peer-review
2 Scopus citations -
Cardioprotection by H2S Donors: Nitric Oxide-Dependent and -Independent Mechanisms
Chatzianastasiou, A., Bibli, S. I., Andreadou, I., Efentakis, P., Kaludercic, N., Wood, M. E., Whiteman, M., Lisa, F. D., Daiber, A., Manolopoulos, V. G., Szabó, C. & Papapetropoulos, D. A., Sep 2016, In: Journal of Pharmacology and Experimental Therapeutics. 358, 3, p. 431-440 10 p.Research output: Contribution to journal › Article › peer-review
43 Scopus citations -
Cystathionine-β-synthase inhibition for colon cancer: Enhancement of the efficacy of aminooxyacetic acid via the prodrug approach
Chao, C., Zatarain, J. R., Ding, Y., Coletta, C., Mrazek, A. A., Druzhyna, N., Johnson, P., Chen, H., Hellmich, J. L., Asimakopoulou, A., Yanagi, K., Olah, G., Szoleczky, P., Törö, G., Bohanon, F. J., Cheema, M., Lewis, R., Eckelbarger, D., Ahmad, A., Módis, K. & 6 others, , 2016, In: Molecular Medicine. 22, p. 361-379 19 p.Research output: Contribution to journal › Article › peer-review
26 Scopus citations -
D -Penicillamine modulates hydrogen sulfide (H2S) pathway through selective inhibition of cystathionine-γ-lyase
Brancaleone, V., Esposito, I., Gargiulo, A., Vellecco, V., Asimakopoulou, A., Citi, V., Calderone, V., Gobbetti, T., Perretti, M., Papapetropoulos, A., Bucci, M. & Cirino, G., May 1 2016, In: British Journal of Pharmacology. 173, 9, p. 1556-1565 10 p.Research output: Contribution to journal › Article › peer-review
Open Access18 Scopus citations -
Exposure to cigarette smoke abrogates the beneficial effect of ischemic postconditioning
Bibli, S. I., Andreadou, I., Glynos, C., Chatzianastasiou, A., Toumpanakis, D., Zakynthinos, S., Vasilakopoulos, T., Iliodromitis, E. K. & Papapetropoulos, A., 2016, In: American Journal of Physiology - Heart and Circulatory Physiology. 311, 5, p. H1321-H1332Research output: Contribution to journal › Article › peer-review
9 Scopus citations -
Regulation and role of endogenously produced hydrogen sulfide in angiogenesis
Katsouda, A., Bibli, S. I., Pyriochou, A., Szabo, C. & Papapetropoulos, A., Nov 1 2016, In: Pharmacological Research. 113, p. 175-185 11 p.Research output: Contribution to journal › Review article › peer-review
42 Scopus citations -
Regulation of soluble guanylyl cyclase redox state by hydrogen sulfide
Zhou, Z., Martin, E., Sharina, I., Esposito, I., Szabo, C., Bucci, M., Cirino, G. & Papapetropoulos, A., Sep 1 2016, In: Pharmacological Research. 111, p. 556-562 7 p.Research output: Contribution to journal › Article › peer-review
40 Scopus citations -
Screening of a composite library of clinically used drugs and well-characterized pharmacological compounds for cystathionine β-synthase inhibition identifies benserazide as a drug potentially suitable for repurposing for the experimental therapy of colon cancer
Druzhyna, N., Szczesny, B., Olah, G., Módis, K., Asimakopoulou, A., Pavlidou, A., Szoleczky, P., Gerö, D., Yanagi, K., Törö, G., López-García, I., Myrianthopoulos, V., Mikros, E., Zatarain, J. R., Chao, C., Papapetropoulos, A., Hellmich, M. R. & Szabo, C., Nov 1 2016, In: Pharmacological Research. 113, p. 18-37 20 p.Research output: Contribution to journal › Article › peer-review
30 Scopus citations -
Synthesis and Pharmacological Evaluation of Novel Adenine-Hydrogen Sulfide Slow Release Hybrids Designed as Multitarget Cardioprotective Agents
Lougiakis, N., Papapetropoulos, A., Gikas, E., Toumpas, S., Efentakis, P., Wedmann, R., Zoga, A., Zhou, Z., Iliodromitis, E. K., Skaltsounis, A. L., Filipovic, M. R., Pouli, N., Marakos, P. & Andreadou, I., Mar 10 2016, In: Journal of medicinal chemistry. 59, 5, p. 1776-1790 15 p.Research output: Contribution to journal › Article › peer-review
18 Scopus citations -
2017
Cooperative Interactions Between NO and H2S: Chemistry, Biology, Physiology, Pathophysiology
Kevil, C., Cortese-Krott, M. M., Nagy, P., Papapetropoulos, A., Feelisch, M. & Szabo, C., Jan 1 2017, Nitric Oxide: Biology and Pathobiology: Third Edition. Elsevier Inc., p. 57-83 27 p.Research output: Chapter in Book/Report/Conference proceeding › Chapter
12 Scopus citations -
Epigenetics-by-Sex Interaction for Coronary Artery Disease Risk Conferred by the Cystathionine γ-Lyase Gene Promoter Methylation
Giannakopoulou, E., Konstantinou, F., Ragia, G., Tavridou, A., Karaglani, M., Chatzaki, E., Papapetropoulos, A., Mikroulis, D. & Manolopoulos, V. G., Dec 1 2017, In: OMICS A Journal of Integrative Biology. 21, 12, p. 741-748 8 p.Research output: Contribution to journal › Article › peer-review
11 Scopus citations -
European contribution to the study of ROS: A summary of the findings and prospects for the future from the COST action BM1203 (EU-ROS)
Egea, J., Fabregat, I., Frapart, Y. M., Ghezzi, P., Görlach, A., Kietzmann, T., Kubaichuk, K., Knaus, U. G., Lopez, M. G., Olaso-Gonzalez, G., Petry, A., Schulz, R., Vina, J., Winyard, P., Abbas, K., Ademowo, O. S., Afonso, C. B., Andreadou, I., Antelmann, H., Antunes, F. & 131 others, , Oct 2017, In: Redox Biology. 13, p. 94-162 69 p.Research output: Contribution to journal › Review article › peer-review
Open Access144 Scopus citations -
Hydrogen sulfide preserves endothelial nitric oxide synthase function by inhibiting proline-rich kinase 2: Implications for cardiomyocyte survival and cardioprotection
Bibli, S. I., Szabo, C., Chatzianastasiou, A., Luck, B., Zukunft, S., Fleming, I. & Papapetropoulos, A., Dec 2017, In: Molecular pharmacology. 92, 6, p. 718-730 13 p.Research output: Contribution to journal › Article › peer-review
7 Scopus citations -
International union of basic and clinical pharmacology. CII: Pharmacological modulation of H2S levels: H2s donors and H2S biosynthesis inhibitors
Szabo, C. & Papapetropoulos, A., Oct 1 2017, In: Pharmacological reviews. 69, 4, p. 497-564 68 p.Research output: Contribution to journal › Article › peer-review
114 Scopus citations -
Reciprocal regulation of eNOS, H2S and CO-synthesizing enzymes in human atheroma: Correlation with plaque stability and effects of simvastatin
Sigala, F., Efentakis, P., Karageorgiadi, D., Filis, K., Zampas, P., Iliodromitis, E. K., Zografos, G., Papapetropoulos, A. & Andreadou, I., Aug 1 2017, In: Redox Biology. 12, p. 70-81 12 p.Research output: Contribution to journal › Article › peer-review
Open Access20 Scopus citations -
THE CONCISE GUIDE TO PHARMACOLOGY 2017/18: Overview
CGTP Collaborators, Dec 2017, In: British Journal of Pharmacology. 174, p. S1-S16Research output: Contribution to journal › Article › peer-review
Open Access171 Scopus citations -
Tyrosine phosphorylation of eNOS regulates myocardial survival after an ischaemic insult: Role of PYK2
Bibli, S. I., Zhou, Z., Zukunft, S., Fisslthaler, B., Andreadou, I., Szabo, C., Brouckaert, P., Fleming, I. & Papapetropoulos, A., Jul 1 2017, In: Cardiovascular research. 113, 8, p. 926-937 12 p.Research output: Contribution to journal › Article › peer-review
15 Scopus citations -
Vascular biology of hydrogen sulfide
Kanagy, N. L., Szabo, C. & Papapetropoulos, A., May 2017, In: American Journal of Physiology - Cell Physiology. 312, 5, p. C537-C549Research output: Contribution to journal › Article › peer-review
75 Scopus citations -
2018
A selective and sensitive method for quantification of endogenous polysulfide production in biological samples
Bibli, S. I., Luck, B., Zukunft, S., Wittig, J., Chen, W., Xian, M., Papapetropoulos, A., Hu, J. & Fleming, I., Sep 2018, In: Redox Biology. 18, p. 295-304 10 p.Research output: Contribution to journal › Article › peer-review
Open Access30 Scopus citations -
Comparison of the effects of e-cigarette vapor with cigarette smoke on lung function and inflammation in mice
Glynos, C., Bibli, S. I., Katsaounou, P., Pavlidou, A., Magkou, C., Karavana, V., Topouzis, S., Kalomenidis, I., Zakynthinos, S. & Papapetropoulos, A., Nov 2018, In: American Journal of Physiology - Lung Cellular and Molecular Physiology. 315, 5, p. L662-L672Research output: Contribution to journal › Article › peer-review
38 Scopus citations -
Corrigendum to “European contribution to the study of ROS: A summary of the findings and prospects for the future from the COST action BM1203 (EU-ROS)” (Redox Biol. (2017) 13 (94–162)(S2213231717303373)(10.1016/j.redox.2017.05.007))
Egea, J., Fabregat, I., Frapart, Y. M., Ghezzi, P., Görlach, A., Kietzmann, T., Kubaichuk, K., Knaus, U. G., Lopez, M. G., Olaso-Gonzalez, G., Petry, A., Schulz, R., Vina, J., Winyard, P., Abbas, K., Ademowo, O. S., Afonso, C. B., Andreadou, I., Antelmann, H., Antunes, F. & 131 others, , Apr 2018, In: Redox Biology. 14, p. 694-696 3 p.Research output: Contribution to journal › Comment/debate › peer-review
Open Access4 Scopus citations -
Drug resistance induces the upregulation of H2S-producing enzymes in HCT116 colon cancer cells
Untereiner, A. A., Pavlidou, A., Druzhyna, N., Papapetropoulos, A., Hellmich, M. R. & Szabo, C., Mar 2018, In: Biochemical Pharmacology. 149, p. 174-185 12 p.Research output: Contribution to journal › Article › peer-review
30 Scopus citations -
Hydrogen sulfide inhibits Kir2 and Kir3 channels by decreasing sensitivity to the phospholipid phosphatidylinositol 4,5-bisphosphate (PIP2)
Ha, J., Xu, Y., Kawano, T., Hendon, T., Baki, L., Garai, S., Papapetropoulos, A., Thakur, G. A., Plant, L. D. & Logothetis, D. E., Mar 9 2018, In: Journal of Biological Chemistry. 293, 10, p. 3546-3561 16 p.Research output: Contribution to journal › Article › peer-review
5 Scopus citations