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Author

  • David Walker
2020
Open Access

Quantitative Proteomics of the Endothelial Secretome Identifies RC0497 as Diagnostic of Acute Rickettsial Spotted Fever Infections

Zhao, Y., Fang, R., Zhang, J., Zhang, Y., Bechelli, J., Smalley, C., Valbuena, G. A., Walker, D. H., Oteo, J. A. & Brasier, A., Feb 2020, In : American Journal of Pathology. 190, 2, p. 306-322 17 p.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations

Recent research milestones in the pathogenesis of human rickettsioses and opportunities ahead

Narra, H. P., Sahni, A., Walker, D. H. & Sahni, S. K., Jun 2020, In : Future Microbiology. 15, 9, p. 753-765 13 p.

Research output: Contribution to journalReview article

The guinea pig model for tick-borne spotted fever rickettsioses: A second look

Stokes, J. V., Walker, D. H. & Varela-Stokes, A. S., Nov 2020, In : Ticks and Tick-borne Diseases. 11, 6, 101538.

Research output: Contribution to journalReview article

Open Access
2018
3 Scopus citations

Chlamydial, Mycoplasmal, Rickettsial, and Ehrlichial Diseases

Walker, D. H., Jan 1 2018, Pulmonary Pathology: A Volume in the Series: Foundations in Diagnostic Pathology. Elsevier Inc., p. 315-326 12 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

2017

A review of the global epidemiology of scrub typhus

Xu, G., Walker, D. H., Jupiter, D., Melby, P. C. & Arcari, C. M., Nov 3 2017, In : PLoS neglected tropical diseases. 11, 11, e0006062.

Research output: Contribution to journalArticle

67 Scopus citations

CD8+T cells provide immune protection against murine disseminated endotheliotropic Orientia tsutsugamushi infection

Xu, G., Mendell, N. L., Liang, Y., Shelite, T. R., Goez-Rivillas, Y., Soong, L., Bouyer, D. H. & Walker, D. H., Jul 19 2017, In : PLoS neglected tropical diseases. 11, 7, e0005763.

Research output: Contribution to journalArticle

13 Scopus citations

Fibroblast growth factor receptor-1 mediates internalization of pathogenic spotted fever rickettsiae into host endothelium

Sahni, A., Patel, J., Narra, H. P., Schroeder, C. L. C., Walker, D. H. & Sahni, S. K., Aug 2017, In : PloS one. 12, 8, e0183181.

Research output: Contribution to journalArticle

6 Scopus citations

Flea-Borne Rickettsioses and Rickettsiae

Blanton, L. S. & Walker, D. H., Jan 2017, In : American Journal of Tropical Medicine and Hygiene. 96, 1, p. 53-56 4 p.

Research output: Contribution to journalReview article

28 Scopus citations

Genotypic characterization of Orientia tsutsugamushi from patients in two geographical locations in Sri Lanka

Premaratna, R., Blanton, L. S., Samaraweera, D. N., de Silva, G. N. N., Chandrasena, N. T. G. A., Walker, D. H. & de Silva, H. J., Jan 13 2017, In : BMC Infectious Diseases. 17, 1, 67.

Research output: Contribution to journalArticle

6 Scopus citations

Mechanisms of immunity to rickettsia and implications for vaccine development

Walker, D., Jan 1 2017, In : Revista Colombiana de Ciencias Pecuarias. 30, p. 262-263 2 p.

Research output: Contribution to journalArticle

Murine models of scrub typhus associated with host control of Orientia tsutsugamushi infection

Mendell, N. L., Bouyer, D. H. & Walker, D. H., Mar 10 2017, In : PLoS neglected tropical diseases. 11, 3, e0005453.

Research output: Contribution to journalArticle

9 Scopus citations

Rickettsiae as Emerging Infectious Agents

Fang, R., Blanton, L. S. & Walker, D. H., Jun 2017, In : Clinics in Laboratory Medicine. 37, 2, p. 383-400 18 p.

Research output: Contribution to journalReview article

24 Scopus citations

Time to Worry about Anthrax Again

Keim, P. S., Walker, D. & Zilinskas, R. A., Mar 14 2017, In : Scientific American. 316, 4, p. 70-75 6 p.

Research output: Contribution to journalArticle

2016

An Intradermal Inoculation Mouse Model for Immunological Investigations of Acute Scrub Typhus and Persistent Infection

Soong, L., Mendell, N. L., Olano, J. P., Rockx-Brouwer, D., Xu, G., Goez-Rivillas, Y., Drom, C., Shelite, T. R., Valbuena, G., Walker, D. H. & Bouyer, D. H., Aug 1 2016, In : PLoS neglected tropical diseases. 10, 8, e0004884.

Research output: Contribution to journalArticle

14 Scopus citations

Editorial: Changing dynamics of human-rickettsial interactions

Walker, D. H., Jan 2016, In : American Journal of Tropical Medicine and Hygiene. 94, 1, p. 3-4 2 p.

Research output: Contribution to journalEditorial

5 Scopus citations

Ehrlichioses: An important one health opportunity

Saito, T. B. & Walker, D. H., Sep 1 2016, In : Veterinary Sciences. 3, 3, 20.

Research output: Contribution to journalReview article

9 Scopus citations

Endothelial Activation and Injury: The Mechanisms of Rickettsial Vasculiti

Sahni, A., Narra, H. P., Walker, D. H. & Sahni, S. K., Jan 1 2016, Vascular Responses to Pathogens. Elsevier Inc., p. 111-122 12 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

4 Scopus citations
9 Scopus citations

Epidemiology, molecular biology, and pathogenic mechanisms of Ehrlichia infections

Yu, X. J. & Walker, D., Jan 1 2016, Rickettsiales: Biology, Molecular Biology, Epidemiology, and Vaccine Development. Springer International Publishing, p. 225-240 16 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

1 Scopus citations

Fatal monocytic ehrlichiosis in woman, Mexico, 2013

Sosa-Gutierrez, C. G., Solorzano-Santos, F., Walker, D. H., Torres, J., Serrano, C. A. & Gordillo-Perez, G., May 2016, In : Emerging infectious diseases. 22, 5, p. 871-874 4 p.

Research output: Contribution to journalArticle

7 Scopus citations

MyD88 mediates instructive signaling in dendritic cells and protective inflammatory response during rickettsial infection

Bechelli, J., Smalley, C., Zhao, X., Judy, B., Valdes, P., Walker, D. H. & Fang, R., Apr 1 2016, In : Infection and immunity. 84, 4, p. 883-893 11 p.

Research output: Contribution to journalArticle

12 Scopus citations

Opossums and cat fleas: New insights in the ecology of murine typhus in Galveston, Texas

Blanton, L. S., Idowu, B. M., Tatsch, T. N., Henderson, J. M., Bouyer, D. H. & Walker, D. H., Aug 2016, In : American Journal of Tropical Medicine and Hygiene. 95, 2, p. 457-461 5 p.

Research output: Contribution to journalArticle

27 Scopus citations

Rickettsia

Walker, D., Oct 6 2016, International Encyclopedia of Public Health. Elsevier Inc., p. 370-377 8 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Rickettsia australis activates inflammasome in human and murine macrophages

Smalley, C., Bechelli, J., Rockx-Brouwer, D., Saito, T., Azar, S. R., Ismail, N., Walker, D. H. & Fang, R., Jun 2016, In : PloS one. 11, 6, e0157231.

Research output: Contribution to journalArticle

13 Scopus citations

Scrub typhus - Scientific neglect, ever-widening impact

Walker, D., Sep 8 2016, In : New England Journal of Medicine. 375, 10, p. 913-915 3 p.

Research output: Contribution to journalShort survey

32 Scopus citations
6 Scopus citations
2015

An animal model of a newly emerging human ehrlichiosis

Saito, T. B., Thirumalapura, N. R., Shelite, T. R., Rockx-Brouwer, D., Popov, V. L. & Walker, D. H., Feb 1 2015, In : Journal of Infectious Diseases. 211, 3, p. 452-461 10 p.

Research output: Contribution to journalArticle

13 Scopus citations

A Tick Vector Transmission Model of Monocytotropic Ehrlichiosis

Saito, T. B. & Walker, D. H., Sep 15 2015, In : Journal of Infectious Diseases. 212, 6, p. 968-977 10 p.

Research output: Contribution to journalArticle

12 Scopus citations
7 Scopus citations

Fever and rash after a safari

Damavandy, A. A., Rojek, N. W., Dugan, E. M., Walker, D. & Norton, S. A., Jan 1 2015, In : Journal of the American Academy of Dermatology. 72, 1, p. e5-e6

Research output: Contribution to journalArticle

Permissive and protective roles for neutrophils in leishmaniasis

Carlsen, E. D., Liang, Y., Shelite, T. R., Walker, D. H., Melby, P. C. & Soong, L., Nov 2015, In : Clinical and Experimental Immunology. 182, 2, p. 109-18 10 p.

Research output: Contribution to journalArticle

30 Scopus citations

Reemergence of murine typhus in galveston, texas, usa, 2013

Blanton, L. S., Vohra, R. F., Bouyer, D. H. & Walker, D. H., 2015, In : Emerging infectious diseases. 21, 3, p. 484-486 3 p.

Research output: Contribution to journalArticle

23 Scopus citations

Rickettsia massiliae and rickettsia conorii israeli spotted fever strain differentially regulate endothelial cell responses

Bechelli, J., Smalley, C., Milhano, N., Walker, D. H. & Fang, R., Sep 22 2015, In : PloS one. 10, 9, e0138830.

Research output: Contribution to journalArticle

5 Scopus citations

The role of CD8 T lymphocytes in rickettsial infections

Walker, D. H. & Dumler, J. S., May 26 2015, In : Seminars in Immunopathology. 37, 3, p. 289-299 11 p.

Research output: Contribution to journalReview article

15 Scopus citations

The role of Rhipicephalus sanguineus sensu lato saliva in the dissemination of Rickettsia conorii in C3H/HeJ mice

Milhano, N., Saito, T. B., Bechelli, J., Fang, R., Vilhena, M., De Sousa, R. & Walker, D. H., Sep 1 2015, In : Medical and Veterinary Entomology. 29, 3, p. 225-229 5 p.

Research output: Contribution to journalArticle

8 Scopus citations
2014

After malaria is controlled, what's next?

Walker, D. H., Jul 2014, In : American Journal of Tropical Medicine and Hygiene. 91, 1, p. 7-10 4 p.

Research output: Contribution to journalEditorial

1 Scopus citations

A Hematogenously Disseminated Orientia tsutsugamsushi-Infected Murine Model of Scrub Typhus

Shelite, T. R., Saito, T. B., Mendell, N. L., Gong, B., Xu, G., Soong, L., Valbuena, G., Bouyer, D. H. & Walker, D. H., Jul 2014, In : PLoS neglected tropical diseases. 8, 7, e2966.

Research output: Contribution to journalArticle

22 Scopus citations

Diseases Caused by Fungi

Walker, D. H. & McGinnis, M. R., Jan 1 2014, Pathobiology of Human Disease: A Dynamic Encyclopedia of Disease Mechanisms. Elsevier Inc., p. 217-221 5 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Ehrlichia

Thirumalapura, N. R. & Walker, D., Nov 26 2014, Molecular Medical Microbiology: Second Edition. Elsevier Ltd, Vol. 3. p. 2011-2032 22 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Ehrlichia chaffeensis (Human Monocytotropic Ehrlichiosis), Anaplasma phagocytophilum (Human Granulocytotropic Anaplasmosis), and Other Anaplasmataceae

Dumler, J. S. & Walker, D., Aug 28 2014, Mandell, Douglas, and Bennett's Principles and Practice of Infectious Diseases. Elsevier Inc., Vol. 2. p. 2227-2233.e3

Research output: Chapter in Book/Report/Conference proceedingChapter

9 Scopus citations

Inactivation of sam-methyltransferase is the mechanism of attenuation of a historic louse borne typhus vaccine strain

Liu, Y., Wu, B., Weinstock, G., Walker, D. H. & Yu, X. J., Nov 20 2014, In : PloS one. 9, 11, e113285.

Research output: Contribution to journalArticle

3 Scopus citations

Interactions of Pathogens with the Host

Walker, D., Jan 1 2014, Pathobiology of Human Disease: A Dynamic Encyclopedia of Disease Mechanisms. Elsevier Inc., p. 214-216 3 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Omplete genome sequence of Ehrlichia muris strain AS145T, a model monocytotropic Ehrlichia strain

Thirumalapura, N. R., Qin, X., Kuriakose, J. A. & Walker, D., 2014, In : Genome Announcements. 2, 1, e01234-13.

Research output: Contribution to journalArticle

5 Scopus citations

Pathogenesis of Infectious Diseases and Mechanisms of Immunity

McBride, J. & Walker, D., Dec 9 2014, Vaccinology: An Essential Guide. Wiley Blackwell, p. 59-72 14 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Principles of Diagnosis of Infectious Diseases

Walker, D., Jan 1 2014, Pathobiology of Human Disease: A Dynamic Encyclopedia of Disease Mechanisms. Elsevier Inc., p. 222-225 4 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Quantitative study of Rickettsia massiliae in Rhipicephalus sanguineus organs

Milhano, N., Popov, V., Vilhena, M., Bouyer, D. H., de Sousa, R. & Walker, D. H., Oct 1 2014, In : Ticks and Tick-borne Diseases. 5, 6, p. 709-714 6 p.

Research output: Contribution to journalArticle

6 Scopus citations