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• 2020

  Discovery of 4-Phenylpiperidine-2-Carboxamide Analogues as Serotonin 5-HT_2CReceptor-Positive Allosteric Modulators with Enhanced Drug-like Properties

  Wold, E. A., Garcia, E. J., Wild, C. T., Miszkiel, J. M., Soto, C. A., Chen, J., Pazdrak, K., Fox, R. G., Anastasio, N. C., Cunningham, K. A. & Zhou, J., Jul 23 2020, In: Journal of medicinal chemistry. 63, 14, p. 7529-7544 16 p.

  Research output: Contribution to journal › Article › peer-review

  • 4-phenylpiperidine
  • Receptor, Serotonin, 5-HT2C
  • Serotonin
  • Pharmaceutical Preparations
  • Serotonin 5-HT2 Receptor Agonists
  2 Scopus citations

• Discovery of Potent and Brain-Penetrant GPR52 Agonist that Suppresses Psychostimulant Behavior

  Wang, P., Felsing, D., Chen, H., Stutz, S. J., Murphy, R., Cunningham, K., Allen, J. & Zhou, J., Nov 25 2020, In: Journal of Medicinal Chemistry. 63, 22, p. 13951 13972 p.

  Research output: Contribution to journal › Article › peer-review

  • G-Protein-Coupled Receptors
  • Brain
  • Proof of Concept Study
  • Structure-Activity Relationship
  • Central Nervous System Diseases

• Editorial: Contemporary Perspective on 5-HT_2C Receptor Function and Its Pharmacological Targeting

  De Deurwaerdère, P., Chagraoui, A. & Cunningham, K. A., Nov 23 2020, In: Frontiers in Pharmacology. 11, 606414.

  Research output: Contribution to journal › Editorial › peer-review

  Open Access

• Fentanyl self-administration impacts brain immune responses in male Sprague-Dawley rats

  Ezeomah, C., Cunningham, K. A., Stutz, S. J., Fox, R. G., Bukreyeva, N., Dineley, K. T., Paessler, S. & Cisneros, I. E., Jul 2020, In: Brain, Behavior, and Immunity. 87, p. 725-738 14 p.

  Research output: Contribution to journal › Article › peer-review

  • Self Administration
  • Fentanyl
  • Interferons
  • Sprague Dawley Rats
  • Brain
  1 Scopus citations

• Inherent Motor Impulsivity Associates with Specific Gene Targets in the Rat Medial Prefrontal Cortex

  Sholler, D. J., Merritt, C. R., Davis-Reyes, B. D., Golovko, G., Anastasio, N. C. & Cunningham, K. A., May 21 2020, In: Neuroscience. 435, p. 161-173 13 p.

  Research output: Contribution to journal › Article › peer-review

  • Impulsive Behavior
  • Prefrontal Cortex
  • Genes
  • Calcium Channels
  • leucyl-cystinyl aminopeptidase
  1 Scopus citations

• Methylation Patterns of the HTR2A Associate With Relapse-Related Behaviors in Cocaine-Dependent Participants

  Land, M. A., Ramesh, D., Miller, A. L., Pyles, R. B., Cunningham, K. A., Moeller, F. G. & Anastasio, N. C., Jun 10 2020, In: Frontiers in Psychiatry. 11, 532.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Cocaine
  • Methylation
  • Recurrence
  • Cues
  • Impulsive Behavior

• Serotonin neurobiology in cocaine use disorder

  Cunningham, K. A., Howell, L. L. & Anastasio, N. C., 2020, Handbook of Behavioral Neuroscience. Elsevier B.V., p. 745-802 58 p. (Handbook of Behavioral Neuroscience; vol. 31).

  Research output: Chapter in Book/Report/Conference proceeding › Chapter

  • Neurobiology
  • Cocaine
  • Serotonin
  • Serotonin Receptors
  • Brain Diseases

• Suppression of cocaine relapse-like behaviors upon pimavanserin and lorcaserin co-administration

  Anastasio, N. C., Sholler, D. J., Fox, R. G., Stutz, S. J., Merritt, C. R., Bjork, J. M., Moeller, F. G. & Cunningham, K. A., May 15 2020, In: Neuropharmacology. 168, 108009.

  Research output: Contribution to journal › Article › peer-review

  • pimavanserin
  • lorcaserin
  • Cocaine
  • Recurrence
  • Self Administration
  4 Scopus citations
• 2019

  Allosteric Modulation of Class A GPCRs: Targets, Agents, and Emerging Concepts

  Wold, E. A., Chen, J., Cunningham, K. A. & Zhou, J., Oct 1 2019, In: Journal of medicinal chemistry. 62, 1, p. 88-127 40 p.

  Research output: Contribution to journal › Article › peer-review

  • G-Protein-Coupled Receptors
  • Drug Discovery
  • Pharmaceutical Chemistry
  • Drug Delivery Systems
  • Clinical Trials
  31 Scopus citations

• Anterior insula activity regulates the associated behaviors of high fat food binge intake and cue reactivity in male rats

  Price, A. E., Stutz, S. J., Hommel, J. D., Anastasio, N. C. & Cunningham, K. A., Feb 1 2019, In: Appetite. 133, p. 231-239 9 p.

  Research output: Contribution to journal › Article › peer-review

  • Cues
  • Eating
  • Fats
  • Bulimia
  • Food
  3 Scopus citations

• Chronic poly-drug administration damages adult mouse brain neural stem cells

  McGrath, E. L., Schlagal, C. R., Cortez, I., Dunn, T. J., Gao, J., Fox, R. G., Stutz, S. J., Kuo, Y. F., Hommel, J. D., Dineley, K. T., Cunningham, K. A., Kaphalia, B. S. & Wu, P., Nov 15 2019, In: Brain Research. 1723, 146425.

  Research output: Contribution to journal › Article › peer-review

  • Neural Stem Cells
  • Brain Stem
  • Cocaine
  • Ethanol
  • Pharmaceutical Preparations

• Cingulo-hippocampal effective connectivity positively correlates with drug-cue attentional bias in opioid use disorder

  Ma, L., Steinberg, J. L., Bjork, J. M., Taylor, B. A., Arias, A. J., Terplan, M., Anastasio, N. C., Zuniga, E. A., Lennon, M., Cunningham, K. A. & Moeller, F. G., Dec 30 2019, In: Psychiatry Research - Neuroimaging. 294, 110977.

  Research output: Contribution to journal › Article › peer-review

  • Attentional Bias
  • Opioid Analgesics
  • Cues
  • Pharmaceutical Preparations
  • Gyrus Cinguli
  2 Scopus citations

• Coevolution of Residues Provides Evidence of a Functional Heterodimer of 5-HT_2AR and 5-HT_2CR Involving Both Intracellular and Extracellular Domains

  Fongang, B., Cunningham, K. A., Rowicka, M. & Kudlicki, A., Aug 1 2019, In: Neuroscience. 412, p. 48-59 12 p.

  Research output: Contribution to journal › Article › peer-review

  • Substance-Related Disorders
  • Single Nucleotide Polymorphism
  • serotonin 5 receptor
  • Proteins
  • Appetite
  1 Scopus citations

• Convergent neural connectivity in motor impulsivity and high-fat food binge-like eating in male Sprague-Dawley rats

  Anastasio, N. C., Stutz, S. J., Price, A. E., Davis-Reyes, B. D., Sholler, D. J., Ferguson, S. M., Neumaier, J. F., Moeller, F. G., Hommel, J. D. & Cunningham, K. A., Sep 1 2019, In: Neuropsychopharmacology. 44, 10, p. 1752-1761 10 p.

  Research output: Contribution to journal › Article › peer-review

  • Bulimia
  • Impulsive Behavior
  • Sprague Dawley Rats
  • Fats
  • Food
  7 Scopus citations

• Design, Synthesis, and Characterization of 4-Undecylpiperidine-2-carboxamides as Positive Allosteric Modulators of the Serotonin (5-HT) 5-HT _2C Receptor

  Wild, C. T., Miszkiel, J. M., Wold, E. A., Soto, C. A., Ding, C., Hartley, R. M., White, M. A., Anastasio, N. C., Cunningham, K. A. & Zhou, J., Oct 1 2019, In: Journal of medicinal chemistry. 62, 1, p. 288-305 18 p.

  Research output: Contribution to journal › Article › peer-review

  • Receptor, Serotonin, 5-HT2C
  • Serotonin
  • 1,2,3,4,8,9,10,10a-octahydro-7bH-cyclopenta(b)(1,4)diazepino(6,7,1hj)indole
  • Cocaine
  • Allosteric Site
  13 Scopus citations

• Endogenous Serotonin 5-HT_2A and 5-HT_2C Receptors Associate in the Medial Prefrontal Cortex

  Price, A. E., Sholler, D. J., Stutz, S. J., Anastasio, N. C. & Cunningham, K. A., Jul 17 2019, In: ACS chemical neuroscience. 10, 7, p. 3241-3248 8 p.

  Research output: Contribution to journal › Article › peer-review

  • Receptor, Serotonin, 5-HT2C
  • Receptor, Serotonin, 5-HT2A
  • Prefrontal Cortex
  • Serotonin
  • Rats
  7 Scopus citations

• In vivo and in vitro analyses of novel peptidomimetic disruptors for the serotonin 5-HT2C receptor interaction with phosphatase and tensin homolog (PTEN)

  Soto, C., Du, H. C., Fox, R., Yang, T., Hooson, J., Anastasio, N. C., Gilbertson, S. R., Cunningham, K. A., Cunningham, K. A. & Gilbertson, S. R., 2019, In: Frontiers in Pharmacology. 10, JULY, 907.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Receptor, Serotonin, 5-HT2C
  • Peptidomimetics
  • Tensins
  • Phosphoric Monoester Hydrolases
  • In Vitro Techniques
  3 Scopus citations

• Leave the Ordinary Elsewhere: Novel Serotonin Mechanisms to Address 21st Century Public Health Challenges

  Sholler, D. J. & Cunningham, K. A., Jul 17 2019, In: ACS chemical neuroscience. 10, 7, p. 3045-3046 2 p.

  Research output: Contribution to journal › Editorial › peer-review

• Positive-allosteric modulation of the 5-HT_2C receptor: implications for neuropsychopharmacology and neurotherapeutics

  Zhou, J. & Cunningham, K. A., Jan 1 2019, In: Neuropsychopharmacology. 44, 1, p. 230-231 2 p.

  Research output: Contribution to journal › Comment/debate › peer-review
  6 Scopus citations

• Protein Co-Evolution Strategies Detect Predicted Functional Interaction Between the Serotonin 5-HT2A and 5-HT2C Receptors

  Fongang, B., Cunningham, K. A., Rowicka, M. & Kudlicki, A., Jan 6 2019, In: Unknown Journal.

  Research output: Contribution to journal › Article › peer-review

  • Receptor, Serotonin, 5-HT2C
  • substance abuse
  • coevolution
  • serotonin
  • Serotonin

• Serotonin 5-HT_2C Receptor Cys23Ser Single Nucleotide Polymorphism Associates with Receptor Function and Localization In Vitro

  Land, M. A., Chapman, H. L., Davis-Reyes, B. D., Felsing, D. E., Allen, J. A., Moeller, F. G., Elferink, L. A., Cunningham, K. A. & Anastasio, N. C., Dec 1 2019, In: Scientific reports. 9, 1, 16737.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Receptor, Serotonin, 5-HT2C
  • Single Nucleotide Polymorphism
  • In Vitro Techniques
  • Alleles
  • Pharmacology
  1 Scopus citations

• Targeting the 5-ht_2c receptor in biological context and the current state of 5-ht_2c receptor ligand development

  Wold, E. A., Wild, C. T., Cunningham, K. A. & Zhou, J., 2019, In: Current topics in medicinal chemistry. 19, 16, p. 1381-1398 18 p.

  Research output: Contribution to journal › Review article › peer-review

  • lorcaserin
  • Serotonin
  • Artificial Receptors
  • Serotonin 5-HT2 Receptor Agonists
  • Receptor, Serotonin, 5-HT2C
  12 Scopus citations

• The 5-HT_2A receptor (5-HT_2AR) regulates impulsive action and cocaine cue reactivity in Male Sprague-Dawley rats

  Sholler, D. J., Stutz, S. J., Fox, R. G., Boone, E. L., Wang, Q., Rice, K. C., Gerard Moeller, F., Anastasio, N. C. & Cunningham, K. A., Jan 2019, In: Journal of Pharmacology and Experimental Therapeutics. 368, 1, p. 41-49 9 p.

  Research output: Contribution to journal › Article › peer-review

  • Receptor, Serotonin, 5-HT2A
  • Cocaine
  • Cues
  • Sprague Dawley Rats
  • pimavanserin
  9 Scopus citations

• Translating pharmacology into therapeutics to fight the opioid crisis

  Marek, G. J., Cunningham, K. A. & Rasmussen, K., 2019, In: Journal of Pharmacology and Experimental Therapeutics. 371, 2, p. 394-395 2 p.

  Research output: Contribution to journal › Editorial › peer-review

  Open Access
• 2015

  5-HT_2C receptor desensitization moderates anxiety in 5-HTT deficient mice: From behavioral to cellular evidence

  Martin, C. B. P., Martin, V. S., Trigo, J. M., Chevarin, C., Maldonado, R., Fink, L. H., Cunningham, K. A., Hamon, M., Lanfumey, L. & Mongeau, R., Feb 2015, In: International Journal of Neuropsychopharmacology. 18, 3

  Research output: Contribution to journal › Article › peer-review

  • Receptor, Serotonin, 5-HT2C
  • Anxiety
  • Serotonin
  • Antidepressive Agents
  • Psychologic Desensitization
  9 Scopus citations

• Evaluation of the dopamine β-hydroxylase (DβH) inhibitor nepicastat in participants who meet criteria for cocaine use disorder

  De La Garza, R., Bubar, M. J., Carbone, C. L., Moeller, F. G., Newton, T. F., Anastasio, N. C., Harper, T. A., Ware, D. L., Fuller, M. A., Holstein, G. J., Jayroe, J. B., Bandak, S. I., Reiman, K. Z., Neale, A. C., Pickford, L. B. & Cunningham, K. A., Jun 3 2015, In: Progress in Neuro-Psychopharmacology and Biological Psychiatry. 59, p. 40-48 9 p.

  Research output: Contribution to journal › Article › peer-review

  • nepicastat
  • Mixed Function Oxygenases
  • Cocaine
  • Dopamine
  • Pharmacokinetics
  8 Scopus citations

• Individual differences in impulsive action reflect variation in the cortical serotonin 5-HT _2A receptor system

  Fink, L. H., Anastasio, N. C., Fox, R. G., Rice, K. C., Moeller, F. G. & Cunningham, K. A., Jul 13 2015, In: Neuropsychopharmacology. 40, 8, p. 1957-1968 12 p.

  Research output: Contribution to journal › Article › peer-review

  • Receptor, Serotonin, 5-HT2A
  • Individuality
  • Serotonin
  • Impulsive Behavior
  • Post-Synaptic Density
  25 Scopus citations

• Inhibitory behavioral control: A stochastic dynamic causal modeling study comparing cocaine dependent subjects and controls

  Ma, L., Steinberg, J. L., Cunningham, K. A., Lane, S. D., Bjork, J. M., Neelakantan, H., Price, A. E., Narayana, P. A., Kosten, T. R., Bechara, A. & Moeller, F. G., 2015, In: NeuroImage: Clinical. 7, p. 837-847 11 p.

  Research output: Contribution to journal › Article › peer-review

  • Cocaine
  • Prefrontal Cortex
  • Impulsive Behavior
  • Gyrus Cinguli
  • Cocaine-Related Disorders
  23 Scopus citations

• Inhibitory behavioral control: a stochastic dynamic causal modeling study using network discovery analysis

  Ma, L., Steinberg, J. L., Cunningham, K., Lane, S. D., Kramer, L. A., Narayana, P. A., Kosten, T. R., Bechara, A. & Moeller, F. G., Apr 1 2015, In: Brain Connectivity. 5, 3, p. 177-186 10 p.

  Research output: Contribution to journal › Article › peer-review

  • Magnetic Resonance Imaging
  • Hippocampus
  • Parahippocampal Gyrus
  • Amygdala
  • Theoretical Models
  9 Scopus citations

• Prevalence of Food Addiction among Low-Income Reproductive-Aged Women

  Berenson, A. B., Laz, T. H., Pohlmeier, A. M., Rahman, M. & Cunningham, K. A., Sep 1 2015, In: Journal of Women's Health. 24, 9, p. 740-744 5 p.

  Research output: Contribution to journal › Article › peer-review

  • Food Addiction
  • Income
  • Food
  • Depression
  • Hyperphagia
  23 Scopus citations

• Rapid-response impulsivity: Definitions, measurement issues, and clinical implications

  Hamilton, K. R., Littlefield, A. K., Anastasio, N. C., Cunningham, K. A., Fink, L. H. L., Wing, V. C., Mathias, C. W., Lane, S. D., Schütz, C. G., Swann, A. C., Lejuez, C. W., Clark, L., Moeller, F. G. & Potenza, M. N., Apr 1 2015, In: Personality Disorders: Theory, Research, and Treatment. 6, 2, p. 168-181 14 p.

  Research output: Contribution to journal › Article › peer-review

  • Impulsive Behavior
  • Research Personnel
  • Personality Disorders
  • Reproducibility of Results
  69 Scopus citations

• Serotonin (5-HT) 5-HT_2A Receptor (5-HT_2AR):5-HT_2CR Imbalance in Medial Prefrontal Cortex Associates with Motor Impulsivity

  Anastasio, N. C., Stutz, S. J., Fink, L. H. L., Swinford-Jackson, S. E., Sears, R. M., Dileone, R. J., Rice, K. C., Moeller, F. G. & Cunningham, K. A., Jul 15 2015, In: ACS chemical neuroscience. 6, 7, p. 1248-1258 11 p.

  Research output: Contribution to journal › Article › peer-review

  • Receptor, Serotonin, 5-HT2A
  • Impulsive Behavior
  • Prefrontal Cortex
  • Serotonin
  • volinanserin
  46 Scopus citations

• Serotonin 5-HT2 receptor interactions with dopamine function: implications for therapeutics in cocaine use disorder

  Howell, L. L. & Cunningham, K. A., 2015, In: Pharmacological reviews. 67, 1, p. 176-197 22 p.

  Research output: Contribution to journal › Review article › peer-review

  • Serotonin 5-HT2 Receptors
  • Cocaine
  • Dopamine
  • Serotonin
  • Cocaine-Related Disorders
  116 Scopus citations

• Serotonin transporter gene promoter polymorphism predicts relationship between years of cocaine use and impulsivity

  Liu, S., Maili, L., Lane, S. D., Schmitz, J. M., Spellicy, C. J., Cunningham, K. A., Moeller, F. G. & Nielsen, D. A., Sep 7 2015, In: Psychiatric Genetics. 25, 5, p. 213-214 2 p.

  Research output: Contribution to journal › Letter › peer-review
  3 Scopus citations
• 2013

  Effects of escitalopram on attentional bias to cocaine-related stimuli and inhibitory control in cocaine-dependent subjects

  Liu, S., Lane, S. D., Schmitz, J. M., Cunningham, K. A., John, V. P. & Moeller, F. G., Sep 1 2013, In: Journal of Psychopharmacology. 27, 9, p. 801-807 7 p.

  Research output: Contribution to journal › Article › peer-review

  • Attentional Bias
  • Citalopram
  • Cocaine
  • Cues
  • Short-Term Memory
  10 Scopus citations

• Elevated expression of serotonin 5-HT_2A receptors in the rat ventral tegmental area enhances vulnerability to the behavioral effects of cocaine

  Herin, D. V., Bubar, M. J., Seitz, P. K., Thomas, M. L., Hillman, G. R., Tarasenko, Y. I., Wu, P. & Cunningham, K. A., May 17 2013, In: Frontiers in Psychiatry. 4, FEB, Article 2.

  Research output: Contribution to journal › Article › peer-review

  • Receptor, Serotonin, 5-HT2A
  • Ventral Tegmental Area
  • Cocaine
  • Locomotion
  • Parvovirus
  10 Scopus citations

• Enhanced leptin sensitivity, reduced adiposity, and improved glucose homeostasis in mice lacking exchange protein directly activated by cyclic AMP Isoform 1

  Yan, J., Mei, F. C., Cheng, H., Lao, D. H., Hu, Y., Wei, J., Patrikeev, I., Hao, D., Stutz, S. J., Dineley, K. T., Motamedi, M., Hommel, J. D., Cunningham, K. A., Chen, J. & Cheng, X., Mar 2013, In: Molecular and cellular biology. 33, 5, p. 918-926 9 p.

  Research output: Contribution to journal › Article › peer-review

  • Adiposity
  • Leptin
  • Cyclic AMP
  • Protein Isoforms
  • Homeostasis
  59 Scopus citations

• Peptide inhibitors disrupt the serotonin 5-HT_2C receptor interaction with phosphatase and tensin homolog to allosterically modulate cellular signaling and behavior

  Anastasio, N. C., Gilbertson, S. R., Bubar, M. J., Agarkov, A., Stutz, S. J., Jeng, Y., Bremer, N. M., Smith, T. D., Fox, R. G., Swinford, S. E., Seitz, P. K., Charendoff, M. N., Craft, J. W., Laezza, F. M., Watson, C. S., Briggs, J. M. & Cunningham, K. A., Jan 23 2013, In: Journal of Neuroscience. 33, 4, p. 1615-1630 16 p.

  Research output: Contribution to journal › Article › peer-review

  • Receptor, Serotonin, 5-HT2C
  • Tensins
  • Phosphoric Monoester Hydrolases
  • Peptides
  • Serotonin
  27 Scopus citations

• Serotonin2C receptors in the ventral pallidum regulate motor function in rats

  Graves, S. M., Viskniskki, A. A., Cunningham, K. A. & Celeste Napier, T., Aug 7 2013, In: NeuroReport. 24, 11, p. 605-608 4 p.

  Research output: Contribution to journal › Article › peer-review

  • Basal Forebrain
  • Receptor, Serotonin, 5-HT2C
  • 6-chloro-2-(1-piperazinyl)pyrazine
  • Serotonin 5-HT2 Receptor Agonists
  • Serotonergic Neurons
  6 Scopus citations

• Synergism between a serotonin 5-HT_2A receptor (5-HT _2AR) antagonist and 5-HT_2CR agonist suggests new pharmacotherapeutics for cocaine addiction

  Cunningham, K. A., Anastasio, N. C., Fox, R. G., Stutz, S. J., Bubar, M. J., Swinford, S. E., Watson, C. S., Gilbertson, S. R., Rice, K. C., Rosenzweig-Lipson, S. & Moeller, F. G., Jan 16 2013, In: ACS chemical neuroscience. 4, 1, p. 110-121 12 p.

  Research output: Contribution to journal › Article › peer-review

  • Serotonin 5-HT2 Receptor Antagonists
  • Cocaine-Related Disorders
  • Cocaine
  • Receptor, Serotonin, 5-HT2A
  • Cues
  66 Scopus citations
• 2012

  Exploration of synthetic approaches and pharmacological evaluation of PNU-69176E and its stereoisomer as 5-HT_2C receptor allosteric modulators

  Ding, C., Bremer, N. M., Smith, T. D., Seitz, P. K., Anastasio, N. C., Cunningham, K. A. & Zhou, J., Jul 18 2012, In: ACS chemical neuroscience. 3, 7, p. 538-545 8 p.

  Research output: Contribution to journal › Article › peer-review

  • L-threo-alpha-D-galacto-octopyranoside methyl-7-chloro-6,7,8-trideoxy-6-(((4-undecyl-2-piperidinyl)carbonyl)amino)-1-thiomonohydrochloride (2S-cis)
  • Receptor, Serotonin, 5-HT2C
  • Stereoisomerism
  • Modulators
  • Serotonin
  21 Scopus citations

• Forced abstinence from cocaine self-administration is associated with DNA methylation changes in myelin genes in the corpus callosum: A preliminary study

  Nielsen, D. A., Huang, W., Hamon, S. C., Maili, L., Witkin, B. M., Fox, R. G., Cunningham, K. A. & Moeller, F. G., 2012, In: Frontiers in Psychiatry. 3, JUN, Article 60.

  Research output: Contribution to journal › Article › peer-review

  • Self Administration
  • Corpus Callosum
  • Myelin Sheath
  • DNA Methylation
  • Cocaine
  27 Scopus citations

• Increased intra-individual reaction time variability in cocaine-dependent subjects: Role of cocaine-related cues

  Liu, S., Lane, S. D., Schmitz, J. M., Green, C. E., Cunningham, K. A. & Moeller, F. G., Feb 2012, In: Addictive Behaviors. 37, 2, p. 193-197 5 p.

  Research output: Contribution to journal › Article › peer-review

  • Cocaine
  • Reaction Time
  • Cues
  • Stroop Test
  • Electronic Data Processing
  15 Scopus citations

• Influence of methamphetamine on genital herpes simplex virus type 2 infection in a mouse model

  Valencia, F., Bubar, M. J., Milligan, G., Cunningham, K. A. & Bourne, N., Sep 2012, In: Sexually Transmitted Diseases. 39, 9, p. 720-725 6 p.

  Research output: Contribution to journal › Article › peer-review

  • Herpes Genitalis
  • Methamphetamine
  • Herpes Simplex
  • Cytokines
  • Sexually Transmitted Diseases
  10 Scopus citations

• Quantitative changes in intracellular calcium and extracellular-regulated kinase activation measured in parallel in CHO cells stably expressing serotonin (5-HT) 5-HT _2A or 5-HT _2C receptors

  Seitz, P. K., Bremer, N. M., McGinnis, A. G., Cunningham, K. A. & Watson, C. S., Mar 7 2012, In: BMC Neuroscience. 13, 1, 25.

  Research output: Contribution to journal › Article › peer-review

  • Receptor, Serotonin, 5-HT2C
  • CHO Cells
  • Serotonin
  • Phosphotransferases
  • Calcium
  19 Scopus citations
• 2011

  5-HT_2c Receptors localize to dopamine and gaba neurons in the rat mesoaccumbens pathway

  Bubar, M. J., Stutz, S. J. & Cunningham, K. A., 2011, In: PloS one. 6, 6, e20508.

  Research output: Contribution to journal › Article › peer-review

  • Receptor, Serotonin, 5-HT2C
  • Ventral Tegmental Area
  • Rats
  • Dopaminergic Neurons
  • dopamine
  76 Scopus citations

• Relationship between attentional bias to cocaine-related stimuli and impulsivity in cocaine-dependent subjects

  Liu, S., Lane, S. D., Schmitz, J. M., Waters, A. J., Cunningham, K. A. & Moeller, F. G., Mar 2011, In: American Journal of Drug and Alcohol Abuse. 37, 2, p. 117-122 6 p.

  Research output: Contribution to journal › Article › peer-review

  • Attentional Bias
  • Impulsive Behavior
  • Cocaine
  • Short-Term Memory
  • Newspapers
  56 Scopus citations

• Selective serotonin 5-HT_2C receptor activation suppresses the reinforcing efficacy of cocaine and sucrose but differentially affects the incentive-salience value of cocaine- vs. sucrose-associated cues

  Cunningham, K. A., Fox, R. G., Anastasio, N. C., Bubar, M. J., Stutz, S. J., Moeller, F. G., Gilbertson, S. R. & Rosenzweig-Lipson, S., Sep 2011, In: Neuropharmacology. 61, 3, p. 513-523 11 p.

  Research output: Contribution to journal › Article › peer-review

  • Receptor, Serotonin, 5-HT2C
  • Cocaine
  • Sucrose
  • 1,2,3,4,8,9,10,10a-octahydro-7bH-cyclopenta(b)(1,4)diazepino(6,7,1hj)indole
  • Cues
  77 Scopus citations

• Serotonin (5-hydroxytryptamine) 5-HT2A receptor: Association with inherent and cocaine-evoked behavioral disinhibition in rats

  Anastasio, N. C., Stoffel, E. C., Fox, R. G., Bubar, M. J., Rice, K. C., Moeller, F. G. & Cunningham, K. A., Jun 2011, In: Behavioural Pharmacology. 22, 3, p. 248-261 14 p.

  Research output: Contribution to journal › Article › peer-review

  • serotonin 5 receptor
  • Receptor, Serotonin, 5-HT2A
  • Impulsive Behavior
  • Cocaine
  • volinanserin
  34 Scopus citations

• Synthesis and evaluation of dimeric derivatives of 5-HT _2A receptor (5-HT _2AR) antagonist M-100907

  Shashack, M. J., Cunningham, K. A., Seitz, P. K., McGinnis, A., Smith, T. D., Watson, C. S. & Gilbertson, S. R., Nov 16 2011, In: ACS chemical neuroscience. 2, 11, p. 640-644 5 p.

  Research output: Contribution to journal › Article › peer-review

  • Bioassay
  • Polyethers
  • catechol
  • Receptor, Serotonin, 5-HT2A
  • Serotonin Receptors
  14 Scopus citations