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• 2019

  Analysis of glucose-derived amino acids involved in one-carbon and cancer metabolism by stable-isotope tracing gas chromatography mass spectrometry

  Sowers, M. L., Herring, J., Zhang, W., Tang, H., Ou, Y., Gu, W. & Zhang, K., Feb 1 2019, In: Analytical Biochemistry. 566, p. 1-9 9 p.

  Research output: Contribution to journal › Article › peer-review

  • Mass spectrometry
  • Metabolism
  • Gas chromatography
  • Gas Chromatography-Mass Spectrometry
  • Isotopes
  6 Scopus citations

• A unique role of carboxylesterase 3 (CES3) in b-adrenergic signaling–stimulated thermogenesis

  Yang, L., Li, X., Tang, H., Gao, Z., Zhang, K. & Sun, K., Jun 1 2019, In: Diabetes. 68, 6, p. 1178-1196 19 p.

  Research output: Contribution to journal › Article › peer-review

  • Carboxylesterase
  • Thermogenesis
  • Adrenergic Agents
  • Adipose Tissue
  • Isoproterenol
  7 Scopus citations

• Sex-specific proteomic changes induced by genetic deletion of fibroblast growth factor 14 (FGF14), a regulator of neuronal ion channels

  Sowers, M. L., Di Re, J., Wadsworth, P. A., Shavkunov, A. S., Lichti, C., Zhang, K. & Laezza, F., Mar 1 2019, In: Proteomes. 7, 1, 5.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • fibroblast growth factor 14
  • Proteomics
  • Ion Channels
  • Schizophrenia
  • Proteome
  5 Scopus citations
• 2018

  Development of a stretch-induced neurotrauma model for medium-throughput screening in vitro: identification of rifampicin as a neuroprotectant

  López-García, I., Gerő, D., Szczesny, B., Szoleczky, P., Olah, G., Módis, K., Zhang, K., Gao, J., Wu, P., Sowers, L. C., DeWitt, D., Prough, D. S. & Szabo, C., 2018, In: British Journal of Pharmacology. 175, 2, p. 284-300 17 p.

  Research output: Contribution to journal › Article › peer-review

  • Rifampin
  • Neuroprotective Agents
  • Wounds and Injuries
  • In Vitro Techniques
  • Neurons
  9 Scopus citations

• Proteomic changes in traumatic brain injury: Experimental approaches

  Sowers, J. L., Wu, P., Zhang, K., DeWitt, D. S. & Prough, D. S., 2018, In: Current opinion in neurology. 31, 6, p. 709-717 9 p.

  Research output: Contribution to journal › Review article › peer-review

  • Traumatic Brain Injury
  • Proteomics
  • Theoretical Models
  • Proteome
  • Mass Spectrometry
  4 Scopus citations

• Role of acetyltransferase PG1842 in gingipain biogenesis in Porphyromonas gingivalis

  Mishra, A., Roy, F., Dou, Y., Zhang, K., Tang, H. & Fletcher, H. M., Dec 1 2018, In: Journal of bacteriology. 200, 24, e00385.

  Research output: Contribution to journal › Article › peer-review

  • Porphyromonas gingivalis argingipain
  • Acetyltransferases
  • Porphyromonas gingivalis
  • Peptide Hydrolases
  • Chronic Periodontitis
  5 Scopus citations
• 2016

  Acetylome study in mouse adipocytes identifies targets of SIRT1 deacetylation in chromatin organization and RNA processing

  Kim, S. Y., Sim, C. K., Tang, H., Han, W., Zhang, K. & Xu, F., May 15 2016, In: Archives of Biochemistry and Biophysics. 598, p. 1-10 10 p.

  Research output: Contribution to journal › Article › peer-review

  • Adipocytes
  • Chromatin
  • RNA
  • Metabolism
  • Lysine
  7 Scopus citations

• An alternative strategy for pan-acetyl-lysine antibody generation

  Kim, S. Y., Sim, C. K., Zhang, Q., Tang, H., Brunmeir, R., Pan, H., Karnani, N., Han, W., Zhang, K. & Xu, F., Sep 2016, In: PloS one. 11, 9, e0162528.

  Research output: Contribution to journal › Article › peer-review

  • Lysine
  • lysine
  • antibodies
  • Antibodies
  • Peptides
  3 Scopus citations

• Measurement of Histone Methylation Dynamics by One-Carbon Metabolic Isotope Labeling and High-energy Collisional Dissociation Methylation Signature Ion Detection

  Tang, H., Tian, B., Brasier, A. R., Sowers, L. C. & Zhang, K., Aug 17 2016, In: Scientific reports. 6, 31537.

  Research output: Contribution to journal › Article › peer-review

  • Carbon Isotopes
  • Isotope Labeling
  • Histones
  • Methylation
  • Ions
  3 Scopus citations
• 2012

  A histone acetyltransferase regulates active DNA demethylation in Arabidopsis

  Qian, W., Miki, D., Zhang, H., Liu, Y., Zhang, X., Tang, K., Kan, Y., La, H., Li, X., Li, S., Zhu, X., Shi, X., Zhang, K., Pontes, O., Chen, X., Liu, R., Gong, Z. & Zhu, J. K., Jun 15 2012, In: Science. 336, 6087, p. 1445-1448 4 p.

  Research output: Contribution to journal › Article › peer-review

  • DNA Demethylation
  • Histone Acetyltransferases
  • Arabidopsis
  • 5-methylcytosine-DNA glycosylase
  • Epigenomics
  135 Scopus citations

• DNA damage induces down-regulation of UDP-glucose ceramide glucosyltransferase, increases ceramide levels and triggers apoptosis in p53-deficient cancer cells

  Haynes, T. A. S., Filippov, V., Filippova, M., Yang, J., Zhang, K. & Duerksen-Hughes, P. J., Jul 2012, In: Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids. 1821, 7, p. 943-953 11 p.

  Research output: Contribution to journal › Article › peer-review

  • ceramide glucosyltransferase
  • Ceramides
  • DNA Damage
  • Down-Regulation
  • Apoptosis
  13 Scopus citations

• Increased ceramide in brains with alzheimer's and other neurodegenerative diseases

  Filippov, V., Song, M. A., Zhang, K., Vinters, H. V., Tung, S., Kirsch, W. M., Yang, J. & Duerksen-Hughes, P. J., 2012, In: Journal of Alzheimer's Disease. 29, 3, p. 537-547 11 p.

  Research output: Contribution to journal › Article › peer-review

  • Ceramides
  • Neurodegenerative Diseases
  • Brain
  • Alzheimer Disease
  • Gene Expression
  104 Scopus citations

• Targeted proteomics for quantification of histone acetylation in Alzheimer's disease

  Zhang, K., Schrag, M., Crofton, A., Trivedi, R., Vinters, H. & Kirsch, W., Apr 2012, In: Proteomics. 12, 8, p. 1261-1268 8 p.

  Research output: Contribution to journal › Article › peer-review

  • Acetylation
  • Proteomics
  • Histones
  • Alzheimer Disease
  • Biomarkers
  120 Scopus citations
• 2011

  Differential histone modification and protein expression associated with cell wall removal and regeneration in rice (Oryza sativa)

  Tan, F., Zhang, K., Mujahid, H., Verma, D. P. S. & Peng, Z., Feb 4 2011, In: Journal of Proteome Research. 10, 2, p. 551-563 13 p.

  Research output: Contribution to journal › Article › peer-review

  • Oryza
  • Histone Code
  • Cell Wall
  • Cells
  • Histones
  20 Scopus citations

• Mass spectrometric studies on epigenetic interaction networks in cell differentiation

  Xiong, L., Darwanto, A., Sharma, S., Herring, J., Hu, S., Filippova, M., Filippov, V., Wang, Y., Chen, C. S., Duerksen-Hughes, P. J., Sowers, L. C. & Zhang, K., Apr 15 2011, In: Journal of Biological Chemistry. 286, 15, p. 13657-13668 12 p.

  Research output: Contribution to journal › Article › peer-review

  • Histones
  • Epigenomics
  • Cell Differentiation
  • RNA Polymerase II
  • Ubiquitination
  21 Scopus citations

• Quantification of ceramide levels in mammalian cells by high performance liquid chromatography coupled to tandem mass spectrometry with multiple-reaction-monitoring mode (HPLC-MS/MS-MRM)

  Zhang, K., Haynes, T. A. S., Filippova, M., Filippov, V. & Duerksen-Hughes, P. J., May 1 2011, In: Analytical Methods. 3, 5, p. 1193-1197 5 p.

  Research output: Contribution to journal › Article › peer-review

  • Ceramides
  • High performance liquid chromatography
  • Mass spectrometry
  • Cells
  • Monitoring
  10 Scopus citations

• Tet-mediated formation of 5-carboxylcytosine and its excision by TDG in mammalian DNA

  He, Y. F., Li, B. Z., Li, Z., Liu, P., Wang, Y., Tang, Q., Ding, J., Jia, Y., Chen, Z., Li, N., Sun, Y., Li, X., Dai, Q., Song, C. X., Zhang, K., He, C. & Xu, G. L., Sep 2 2011, In: Science. 333, 6047, p. 1303-1307 5 p.

  Research output: Contribution to journal › Article › peer-review

  • 5-carboxylcytosine
  • Thymine DNA Glycosylase
  • 5-Methylcytosine
  • 5-hydroxymethylcytosine
  • Dioxygenases
  1661 Scopus citations