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• 2019

  Association study of the CTH 1364 G>T polymorphism with coronary artery disease in the Greek population

  Giannakopoulou, E., Konstantinou, F., Ragia, G., Gerontitis, Z., Tavridou, A., Papapetropoulos, A., Mikroulis, D. & Manolopoulos, V. G., Jan 1 2019, In: Drug Metabolism and Personalized Therapy. 34, 1, 20180033.

  Research output: Contribution to journal › Article › peer-review

  • Coronary Artery Bypass
  • Coronary Artery Disease
  • Genotype
  • Population
  • Cystathionine
  2 Scopus citations

• Cystathionine γ Lyase Sulfhydrates the RNA Binding Protein Human Antigen R to Preserve Endothelial Cell Function and Delay Atherogenesis

  Bibli, S. I., Hu, J., Sigala, F., Wittig, I., Heidler, J., Zukunft, S., Tsilimigras, D. I., Randriamboavonjy, V., Wittig, J., Kojonazarov, B., Schürmann, C., Siragusa, M., Siuda, D., Luck, B., Abdel Malik, R., Filis, K. A., Zografos, G., Chen, C., Wang, D. W., Pfeilschifter, J. & 4 others, Brandes, R. P., Szabo, C., Papapetropoulos, A. & Fleming, I., Jan 2 2019, In: Circulation. 139, 1, p. 101-114 14 p.

  Research output: Contribution to journal › Article › peer-review

  • Cystathionine
  • Lyases
  • RNA-Binding Proteins
  • Atherosclerosis
  • Endothelial Cells
  28 Scopus citations

• Investigating and re-evaluating the role of glycogen synthase kinase 3 beta kinase as a molecular target for cardioprotection by using novel pharmacological inhibitors

  Nikolaou, P. E., Boengler, K., Efentakis, P., Vouvogiannopoulou, K., Zoga, A., Gaboriaud-Kolar, N., Myrianthopoulos, V., Alexakos, P., Kostomitsopoulos, N., Rerras, I., Tsantili-Kakoulidou, A., Skaltsounis, A. L., Papapetropoulos, A., Iliodromitis, E. K., Schulz, R. & Andreadou, I., Jun 1 2019, In: Cardiovascular research. 115, 7, p. 1228-1243 16 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Glycogen Synthase Kinase 3 beta
  • Phosphotransferases
  • Pharmacology
  • 6-bromoindirubin-3'-oxime
  • Autophagy-Related Proteins
  11 Scopus citations

• Nitroglycerine limits infarct size through S-nitrosation of cyclophilin D: A novel mechanism for an old drug

  Bibli, S. I., Papapetropoulos, A., Iliodromitis, E. K., Daiber, A., Randriamboavonjy, V., Steven, S., Brouckaert, P., Chatzianastasiou, A., Kypreos, K. E., Hausenloy, D. J., Fleming, I. & Andreadou, I., Mar 1 2019, In: Cardiovascular research. 115, 3, p. 625-636 12 p.

  Research output: Contribution to journal › Article › peer-review

  • cyclophilin D
  • Nitrosation
  • Nitroglycerin
  • Nitric Oxide Synthase Type III
  • Pharmaceutical Preparations
  11 Scopus citations

• THE CONCISE GUIDE TO PHARMACOLOGY 2019/20: Enzymes

  CGTP Collaborators, Dec 1 2019, In: British Journal of Pharmacology. 176, S1, p. S297-S396

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Terminology
  • Pharmacology
  • Enzymes
  • Ligands
  • Drug Receptors
  190 Scopus citations
• 2018

  A selective and sensitive method for quantification of endogenous polysulfide production in biological samples

  Bibli, S. I., Luck, B., Zukunft, S., Wittig, J., Chen, W., Xian, M., Papapetropoulos, A., Hu, J. & Fleming, I., Sep 2018, In: Redox Biology. 18, p. 295-304 10 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • polysulfide
  • Sulfur
  • Gasotransmitters
  • Cystathionine
  • Endothelial cells
  28 Scopus citations

• Comparison of the effects of e-cigarette vapor with cigarette smoke on lung function and inflammation in mice

  Glynos, C., Bibli, S. I., Katsaounou, P., Pavlidou, A., Magkou, C., Karavana, V., Topouzis, S., Kalomenidis, I., Zakynthinos, S. & Papapetropoulos, A., Nov 2018, In: American Journal of Physiology - Lung Cellular and Molecular Physiology. 315, 5, p. L662-L672

  Research output: Contribution to journal › Article › peer-review

  • Electronic Nicotine Delivery Systems
  • Smoke
  • Tobacco Products
  • Pneumonia
  • Bronchoalveolar Lavage Fluid
  36 Scopus citations

• Corrigendum to “European contribution to the study of ROS: A summary of the findings and prospects for the future from the COST action BM1203 (EU-ROS)” (Redox Biol. (2017) 13 (94–162)(S2213231717303373)(10.1016/j.redox.2017.05.007))

  Egea, J., Fabregat, I., Frapart, Y. M., Ghezzi, P., Görlach, A., Kietzmann, T., Kubaichuk, K., Knaus, U. G., Lopez, M. G., Olaso-Gonzalez, G., Petry, A., Schulz, R., Vina, J., Winyard, P., Abbas, K., Ademowo, O. S., Afonso, C. B., Andreadou, I., Antelmann, H., Antunes, F. & 131 others, Aslan, M., Bachschmid, M. M., Barbosa, R. M., Belousov, V., Berndt, C., Bernlohr, D., Bertrán, E., Bindoli, A., Bottari, S. P., Brito, P. M., Carrara, G., Casas, A. I., Chatzi, A., Chondrogianni, N., Conrad, M., Cooke, M. S., Costa, J. G., Cuadrado, A., My-Chan Dang, P., De Smet, B., Debelec-Butuner, B., Dias, I. H. K., Dunn, J. D., Edson, A. J., El Assar, M., El-Benna, J., Ferdinandy, P., Fernandes, A. S., Fladmark, K. E., Förstermann, U., Giniatullin, R., Giricz, Z., Görbe, A., Griffiths, H., Hampl, V., Hanf, A., Herget, J., Hernansanz-Agustín, P., Hillion, M., Huang, J., Ilikay, S., Jansen-Dürr, P., Jaquet, V., Joles, J. A., Kalyanaraman, B., Kaminskyy, D., Karbaschi, M., Kleanthous, M., Klotz, L. O., Korac, B., Korkmaz, K. S., Koziel, R., Kračun, D., Krause, K. H., Křen, V., Krieg, T., Laranjinha, J., Lazou, A., Li, H., Martínez-Ruiz, A., Matsui, R., McBean, G. J., Meredith, S. P., Messens, J., Miguel, V., Mikhed, Y., Milisav, I., Milković, L., Miranda-Vizuete, A., Mojović, M., Monsalve, M., Mouthuy, P. A., Mulvey, J., Münzel, T., Muzykantov, V., Nguyen, I. T. N., Oelze, M., Oliveira, N. G., Palmeira, C. M., Papaevgeniou, N., Pavićević, A., Pedre, B., Peyrot, F., Phylactides, M., Pircalabioru, G. G., Pitt, A. R., Poulsen, H. E., Prieto, I., Rigobello, M. P., Robledinos-Antón, N., Rodríguez-Mañas, L., Rolo, A. P., Rousset, F., Ruskovska, T., Saraiva, N., Sasson, S., Schröder, K., Semen, K., Seredenina, T., Shakirzyanova, A., Smith, G. L., Soldati, T., Sousa, B. C., Spickett, C. M., Stancic, A., Stasia, M. J., Steinbrenner, H., Stepanić, V., Steven, S., Tokatlidis, K., Tuncay, E., Turan, B., Ursini, F., Vacek, J., Vajnerova, O., Valentová, K., Van Breusegem, F., Varisli, L., Veal, E. A., Yalçın, A. S., Yelisyeyeva, O., Žarković, N., Zatloukalová, M., Zielonka, J., Touyz, R. M., Papapetropoulos, A., Grune, T., Lamas, S., Schmidt, H. H. H. W., Di Lisa, F. & Daiber, A., Apr 2018, In: Redox Biology. 14, p. 694-696 3 p.

  Research output: Contribution to journal › Comment/debate › peer-review

  Open Access

  • Oxidation-Reduction
  • Technology
  • Publications
  • European Union
  • Emotions
  4 Scopus citations

• Drug resistance induces the upregulation of H₂S-producing enzymes in HCT116 colon cancer cells

  Untereiner, A. A., Pavlidou, A., Druzhyna, N., Papapetropoulos, A., Hellmich, M. R. & Szabo, C., Mar 2018, In: Biochemical Pharmacology. 149, p. 174-185 12 p.

  Research output: Contribution to journal › Article › peer-review

  • Cells
  • Fluorouracil
  • Drug Resistance
  • Colonic Neoplasms
  • Up-Regulation
  28 Scopus citations

• Hydrogen sulfide inhibits Kir2 and Kir3 channels by decreasing sensitivity to the phospholipid phosphatidylinositol 4,5-bisphosphate (PIP₂)

  Ha, J., Xu, Y., Kawano, T., Hendon, T., Baki, L., Garai, S., Papapetropoulos, A., Thakur, G. A., Plant, L. D. & Logothetis, D. E., Mar 9 2018, In: Journal of Biological Chemistry. 293, 10, p. 3546-3561 16 p.

  Research output: Contribution to journal › Article › peer-review

  • Hydrogen Sulfide
  • Phosphatidylinositols
  • Cysteine
  • Phospholipids
  • Gasotransmitters
  5 Scopus citations

• Inventing new therapies without reinventing the wheel: the power of drug repurposing

  Papapetropoulos, A. & Szabo, C., 2018, In: British Journal of Pharmacology. 175, 2, p. 165-167 3 p.

  Research output: Contribution to journal › Editorial › peer-review

  • Drug Repositioning
  • Therapeutics
  19 Scopus citations

• Mercaptopyruvate acts as endogenous vasodilator independently of 3-mercaptopyruvate sulfurtransferase activity

  Mitidieri, E., Tramontano, T., Gurgone, D., Citi, V., Calderone, V., Brancaleone, V., Katsouda, A., Nagahara, N., Papapetropoulos, A., Cirino, G., d'Emmanuele di Villa Bianca, R. & Sorrentino, R., May 1 2018, In: Nitric Oxide - Biology and Chemistry. 75, p. 53-59 7 p.

  Research output: Contribution to journal › Article › peer-review

  • 3-mercaptopyruvic acid
  • Vasodilator Agents
  • N(G)-iminoethylornithine
  • Cystathionine
  • Endothelium
  16 Scopus citations

• Mitochondrial DNA damage and subsequent activation of Z-DNA binding protein 1 links oxidative stress to inflammation in epithelial cells

  Szczesny, B., Marcatti, M., Ahmad, A., Montalbano, M., Brunyánszki, A., Bibli, S. I., Papapetropoulos, A. & Szabo, C., Dec 1 2018, In: Scientific reports. 8, 1, 914.

  Research output: Contribution to journal › Article › peer-review

  • Z-Form DNA
  • DNA-Binding Proteins
  • Mitochondrial DNA
  • DNA Damage
  • Oxidative Stress
  29 Scopus citations

• Reduced adipose tissue H₂S in obesity

  Katsouda, A., Szabo, C. & Papapetropoulos, A., Feb 2018, In: Pharmacological Research. 128, p. 190-199 10 p.

  Research output: Contribution to journal › Article › peer-review

  • Cystathionine
  • 3-mercaptopyruvic acid
  • Lyases
  • Adipose Tissue
  • Obesity
  11 Scopus citations
• 2017

  Cooperative Interactions Between NO and H₂S: Chemistry, Biology, Physiology, Pathophysiology

  Kevil, C., Cortese-Krott, M. M., Nagy, P., Papapetropoulos, A., Feelisch, M. & Szabo, C., Jan 1 2017, Nitric Oxide: Biology and Pathobiology: Third Edition. Elsevier Inc., p. 57-83 27 p.

  Research output: Chapter in Book/Report/Conference proceeding › Chapter

  • Sulfides
  • Physiology
  • polysulfide
  • Chemical activation
  • Cyclic GMP-Dependent Protein Kinases
  12 Scopus citations

• Epigenetics-by-Sex Interaction for Coronary Artery Disease Risk Conferred by the Cystathionine γ-Lyase Gene Promoter Methylation

  Giannakopoulou, E., Konstantinou, F., Ragia, G., Tavridou, A., Karaglani, M., Chatzaki, E., Papapetropoulos, A., Mikroulis, D. & Manolopoulos, V. G., Dec 1 2017, In: OMICS A Journal of Integrative Biology. 21, 12, p. 741-748 8 p.

  Research output: Contribution to journal › Article › peer-review

  • Methylation
  • Cystathionine
  • Lyases
  • Genes
  • Epigenomics
  10 Scopus citations

• European contribution to the study of ROS: A summary of the findings and prospects for the future from the COST action BM1203 (EU-ROS)

  Egea, J., Fabregat, I., Frapart, Y. M., Ghezzi, P., Görlach, A., Kietzmann, T., Kubaichuk, K., Knaus, U. G., Lopez, M. G., Olaso-Gonzalez, G., Petry, A., Schulz, R., Vina, J., Winyard, P., Abbas, K., Ademowo, O. S., Afonso, C. B., Andreadou, I., Antelmann, H., Antunes, F. & 131 others, Aslan, M., Bachschmid, M. M., Barbosa, R. M., Belousov, V., Berndt, C., Bernlohr, D., Bertrán, E., Bindoli, A., Bottari, S. P., Brito, P. M., Carrara, G., Casas, A. I., Chatzi, A., Chondrogianni, N., Conrad, M., Cooke, M. S., Costa, J. G., Cuadrado, A., My-Chan Dang, P., De Smet, B., Debelec-Butuner, B., Dias, I. H. K., Dunn, J. D., Edson, A. J., El Assar, M., El-Benna, J., Ferdinandy, P., Fernandes, A. S., Fladmark, K. E., Förstermann, U., Giniatullin, R., Giricz, Z., Görbe, A., Griffiths, H., Hampl, V., Hanf, A., Herget, J., Hernansanz-Agustín, P., Hillion, M., Huang, J., Ilikay, S., Jansen-Dürr, P., Jaquet, V., Joles, J. A., Kalyanaraman, B., Kaminskyy, D., Karbaschi, M., Kleanthous, M., Klotz, L. O., Korac, B., Korkmaz, K. S., Koziel, R., Kračun, D., Krause, K. H., Křen, V., Krieg, T., Laranjinha, J., Lazou, A., Li, H., Martínez-Ruiz, A., Matsui, R., McBean, G. J., Meredith, S. P., Messens, J., Miguel, V., Mikhed, Y., Milisav, I., Milković, L., Miranda-Vizuete, A., Mojović, M., Monsalve, M., Mouthuy, P. A., Mulvey, J., Münzel, T., Muzykantov, V., Nguyen, I. T. N., Oelze, M., Oliveira, N. G., Palmeira, C. M., Papaevgeniou, N., Pavićević, A., Pedre, B., Peyrot, F., Phylactides, M., Pircalabioru, G. G., Pitt, A. R., Poulsen, H. E., Prieto, I., Rigobello, M. P., Robledinos-Antón, N., Rodríguez-Mañas, L., Rolo, A. P., Rousset, F., Ruskovska, T., Saraiva, N., Sasson, S., Schröder, K., Semen, K., Seredenina, T., Shakirzyanova, A., Smith, G. L., Soldati, T., Sousa, B. C., Spickett, C. M., Stancic, A., Stasia, M. J., Steinbrenner, H., Stepanić, V., Steven, S., Tokatlidis, K., Tuncay, E., Turan, B., Ursini, F., Vacek, J., Vajnerova, O., Valentová, K., Van Breusegem, F., Varisli, L., Veal, E. A., Yalçın, A. S., Yelisyeyeva, O., Žarković, N., Zatloukalová, M., Zielonka, J., Touyz, R. M., Papapetropoulos, A., Grune, T., Lamas, S., Schmidt, H. H. H. W., Di Lisa, F. & Daiber, A., Oct 2017, In: Redox Biology. 13, p. 94-162 69 p.

  Research output: Contribution to journal › Review article › peer-review

  Open Access

  • Oxidation-Reduction
  • Oxidative stress
  • Reactive Nitrogen Species
  • Technology
  • Reactive Oxygen Species
  136 Scopus citations

• Hydrogen sulfide preserves endothelial nitric oxide synthase function by inhibiting proline-rich kinase 2: Implications for cardiomyocyte survival and cardioprotection

  Bibli, S. I., Szabo, C., Chatzianastasiou, A., Luck, B., Zukunft, S., Fleming, I. & Papapetropoulos, A., Dec 2017, In: Molecular pharmacology. 92, 6, p. 718-730 13 p.

  Research output: Contribution to journal › Article › peer-review

  • Focal Adhesion Kinase 2
  • Hydrogen Sulfide
  • Nitric Oxide Synthase Type III
  • Proline
  • Cardiac Myocytes
  7 Scopus citations

• International union of basic and clinical pharmacology. CII: Pharmacological modulation of H₂S levels: H₂s donors and H₂S biosynthesis inhibitors

  Szabo, C. & Papapetropoulos, A., Oct 1 2017, In: Pharmacological reviews. 69, 4, p. 497-564 68 p.

  Research output: Contribution to journal › Article › peer-review

  • Clinical Pharmacology
  • Gasotransmitters
  • Cystathionine
  • 2-(6-methoxy-napthalen-2-yl)-propionic acid 4-thiocarbamoyl-phenyl ester
  • Pharmacology
  110 Scopus citations

• Reciprocal regulation of eNOS, H₂S and CO-synthesizing enzymes in human atheroma: Correlation with plaque stability and effects of simvastatin

  Sigala, F., Efentakis, P., Karageorgiadi, D., Filis, K., Zampas, P., Iliodromitis, E. K., Zografos, G., Papapetropoulos, A. & Andreadou, I., Aug 1 2017, In: Redox Biology. 12, p. 70-81 12 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Simvastatin
  • Atherosclerotic Plaques
  • Carbon Monoxide
  • Cystathionine beta-Synthase
  • Heme Oxygenase-1
  20 Scopus citations

• THE CONCISE GUIDE TO PHARMACOLOGY 2017/18: Overview

  CGTP Collaborators, Dec 2017, In: British Journal of Pharmacology. 174, p. S1-S16

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Terminology
  • Pharmacology
  • Ion Channels
  • Ligands
  • Ligand-Gated Ion Channels
  170 Scopus citations

• Tyrosine phosphorylation of eNOS regulates myocardial survival after an ischaemic insult: Role of PYK2

  Bibli, S. I., Zhou, Z., Zukunft, S., Fisslthaler, B., Andreadou, I., Szabo, C., Brouckaert, P., Fleming, I. & Papapetropoulos, A., Jul 1 2017, In: Cardiovascular research. 113, 8, p. 926-937 12 p.

  Research output: Contribution to journal › Article › peer-review

  • Focal Adhesion Kinase 2
  • Tyrosine
  • Phosphorylation
  • Cardiac Myocytes
  • Nitric Oxide
  15 Scopus citations

• Vascular biology of hydrogen sulfide

  Kanagy, N. L., Szabo, C. & Papapetropoulos, A., May 2017, In: American Journal of Physiology - Cell Physiology. 312, 5, p. C537-C549

  Research output: Contribution to journal › Article › peer-review

  • Hydrogen Sulfide
  • Blood Vessels
  • Gasotransmitters
  • Capillary Permeability
  • Atherosclerotic Plaques
  75 Scopus citations
• 2016

  ¹H, ¹³C, ¹⁵N backbone and side-chain resonance assignment of Nostoc sp. C139A variant of the heme–nitric oxide/oxygen binding (H-NOX) domain

  Alexandropoulos, I. I., Argyriou, A. I., Marousis, K. D., Topouzis, S., Papapetropoulos, A. & Spyroulias, G. A., Oct 1 2016, In: Biomolecular NMR Assignments. 10, 2, p. 395-400 6 p.

  Research output: Contribution to journal › Article › peer-review

  • Nostoc
  • Oxides
  • Oxygen
  • Soluble Guanylyl Cyclase
  • Heme
  2 Scopus citations

• Cardioprotection by H₂S Donors: Nitric Oxide-Dependent and -Independent Mechanisms

  Chatzianastasiou, A., Bibli, S. I., Andreadou, I., Efentakis, P., Kaludercic, N., Wood, M. E., Whiteman, M., Lisa, F. D., Daiber, A., Manolopoulos, V. G., Szabó, C. & Papapetropoulos, D. A., Sep 2016, In: Journal of Pharmacology and Experimental Therapeutics. 358, 3, p. 431-440 10 p.

  Research output: Contribution to journal › Article › peer-review

  • sodium sulfide
  • Nitric Oxide Donors
  • GYY 4137
  • cyclophilin D
  • Permeability
  42 Scopus citations

• Cystathionine-β-synthase inhibition for colon cancer: Enhancement of the efficacy of aminooxyacetic acid via the prodrug approach

  Chao, C., Zatarain, J. R., Ding, Y., Coletta, C., Mrazek, A. A., Druzhyna, N., Johnson, P., Chen, H., Hellmich, J. L., Asimakopoulou, A., Yanagi, K., Olah, G., Szoleczky, P., Törö, G., Bohanon, F. J., Cheema, M., Lewis, R., Eckelbarger, D., Ahmad, A., Módis, K. & 6 others, Untereiner, A., Szczesny, B., Papapetropoulos, A., Zhou, J., Hellmich, M. R. & Szabo, C., 2016, In: Molecular Medicine. 22, p. 361-379 19 p.

  Research output: Contribution to journal › Article › peer-review

  • Aminooxyacetic Acid
  • Cystathionine
  • Prodrugs
  • Colonic Neoplasms
  • Neoplasms
  24 Scopus citations

• D -Penicillamine modulates hydrogen sulfide (H₂S) pathway through selective inhibition of cystathionine-γ-lyase

  Brancaleone, V., Esposito, I., Gargiulo, A., Vellecco, V., Asimakopoulou, A., Citi, V., Calderone, V., Gobbetti, T., Perretti, M., Papapetropoulos, A., Bucci, M. & Cirino, G., May 1 2016, In: British Journal of Pharmacology. 173, 9, p. 1556-1565 10 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Cystathionine
  • Lyases
  • Hydrogen Sulfide
  • Penicillamine
  • Inhibition (Psychology)
  18 Scopus citations

• Exposure to cigarette smoke abrogates the beneficial effect of ischemic postconditioning

  Bibli, S. I., Andreadou, I., Glynos, C., Chatzianastasiou, A., Toumpanakis, D., Zakynthinos, S., Vasilakopoulos, T., Iliodromitis, E. K. & Papapetropoulos, A., 2016, In: American Journal of Physiology - Heart and Circulatory Physiology. 311, 5, p. H1321-H1332

  Research output: Contribution to journal › Article › peer-review

  • Ischemic Postconditioning
  • Smoke
  • Tobacco Products
  • Air
  • Conditioning (Psychology)
  9 Scopus citations

• Regulation and role of endogenously produced hydrogen sulfide in angiogenesis

  Katsouda, A., Bibli, S. I., Pyriochou, A., Szabo, C. & Papapetropoulos, A., Nov 1 2016, In: Pharmacological Research. 113, p. 175-185 11 p.

  Research output: Contribution to journal › Review article › peer-review

  • Hydrogen Sulfide
  • Vascular Endothelial Growth Factor A
  • Enzymes
  • Endothelial Cells
  • KATP Channels
  42 Scopus citations

• Regulation of soluble guanylyl cyclase redox state by hydrogen sulfide

  Zhou, Z., Martin, E., Sharina, I., Esposito, I., Szabo, C., Bucci, M., Cirino, G. & Papapetropoulos, A., Sep 1 2016, In: Pharmacological Research. 111, p. 556-562 7 p.

  Research output: Contribution to journal › Article › peer-review

  • Hydrogen Sulfide
  • Soluble Guanylyl Cyclase
  • Oxidation-Reduction
  • Nitric Oxide
  • BAY 58-2667
  40 Scopus citations

• Screening of a composite library of clinically used drugs and well-characterized pharmacological compounds for cystathionine β-synthase inhibition identifies benserazide as a drug potentially suitable for repurposing for the experimental therapy of colon cancer

  Druzhyna, N., Szczesny, B., Olah, G., Módis, K., Asimakopoulou, A., Pavlidou, A., Szoleczky, P., Gerö, D., Yanagi, K., Törö, G., López-García, I., Myrianthopoulos, V., Mikros, E., Zatarain, J. R., Chao, C., Papapetropoulos, A., Hellmich, M. R. & Szabo, C., Nov 1 2016, In: Pharmacological Research. 113, p. 18-37 20 p.

  Research output: Contribution to journal › Article › peer-review

  • Benserazide
  • Cystathionine
  • Investigational Therapies
  • Inhibitory Concentration 50
  • Colonic Neoplasms
  29 Scopus citations

• Synthesis and Pharmacological Evaluation of Novel Adenine-Hydrogen Sulfide Slow Release Hybrids Designed as Multitarget Cardioprotective Agents

  Lougiakis, N., Papapetropoulos, A., Gikas, E., Toumpas, S., Efentakis, P., Wedmann, R., Zoga, A., Zhou, Z., Iliodromitis, E. K., Skaltsounis, A. L., Filipovic, M. R., Pouli, N., Marakos, P. & Andreadou, I., Mar 10 2016, In: Journal of medicinal chemistry. 59, 5, p. 1776-1790 15 p.

  Research output: Contribution to journal › Article › peer-review

  • Cardiotonic Agents
  • Hydrogen Sulfide
  • Adenine
  • Pharmacology
  • Ether
  18 Scopus citations
• 2014

  Effect of S-adenosyl-L-methionine (SAM), an allosteric activator of cystathionine-β-synthase (CBS) on colorectal cancer cell proliferation and bioenergetics in vitro

  Módis, K., Coletta, C., Asimakopoulou, A., Szczesny, B., Chao, C., Papapetropoulos, A., Hellmich, M. R. & Szabo, C., Sep 15 2014, In: Nitric Oxide - Biology and Chemistry. 41, p. 146-156 11 p.

  Research output: Contribution to journal › Article › peer-review

  • Cystathionine
  • Cell proliferation
  • S-Adenosylmethionine
  • Energy Metabolism
  • Colorectal Neoplasms
  46 Scopus citations

• Hydrogen sulfide accounts for the peripheral vascular effects of zofenopril independently of ACE inhibition

  Bucci, M., Vellecco, V., Cantalupo, A., Brancaleone, V., Zhou, Z., Evangelista, S., Calderone, V., Papapetropoulos, A. & Cirino, G., Jan 1 2014, In: Cardiovascular research. 102, 1, p. 138-147 10 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • zofenopril
  • Hydrogen Sulfide
  • Peptidyl-Dipeptidase A
  • Cystathionine
  • Inhibition (Psychology)
  53 Scopus citations

• Modulation of poly(ADP-Ribose) polymerase-1 (PARP-1)-mediated oxidative cell injury by ring finger protein 146 (RNF146) in cardiac myocytes

  Gerö, D., Szoleczky, P., Chatzianastasiou, A., Papapetropoulos, A. & Szabo, C., 2014, In: Molecular Medicine. 20, 1, p. 313-328 16 p.

  Research output: Contribution to journal › Article › peer-review

  • Finger Injuries
  • Poly (ADP-Ribose) Polymerase-1
  • Cardiac Myocytes
  • Fingers
  • Proteins
  20 Scopus citations

• Nitric oxide and heat shock protein 90 activate soluble guanylate cyclase by driving rapid change in its subunit interactions and heme content

  Ghosh, A., Stasch, J. P., Papapetropoulos, A. & Stuehr, D. J., May 30 2014, In: Journal of Biological Chemistry. 289, 22, p. 15259-15271 13 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • HSP90 Heat-Shock Proteins
  • Soluble Guanylyl Cyclase
  • Heme
  • Guanylate Cyclase
  • guanylate cyclase 1
  31 Scopus citations

• Regulation of mitochondrial bioenergetic function by hydrogen sulfide. Part II Pathophysiological and therapeutic aspects

  Módis, K., Bos, E. M., Calzia, E., Van Goor, H., Coletta, C., Papapetropoulos, A., Hellmich, M. R., Radermacher, P., Bouillaud, F. & Szabo, C., Apr 2014, In: British Journal of Pharmacology. 171, 8, p. 2123-2146 24 p.

  Research output: Contribution to journal › Review article › peer-review

  • Hydrogen Sulfide
  • Energy Metabolism
  • Cystathionine
  • Pharmacology
  • Cell Hypoxia
  79 Scopus citations
• 2012

  Angiopoietin-2 enhances survival in experimental sepsis induced by multidrug-resistant Pseudomonas aeruginosa

  Tzepi, I. M., Giamarellos-Bourboulis, E. J., Carrer, D. P., Tsaganos, T., Claus, R. A., Vaki, I., Pelekanou, A., Kotsaki, A., Tziortzioti, V., Topouzis, S., Bauer, M. & Papapetropoulos, A., Nov 1 2012, In: Journal of Pharmacology and Experimental Therapeutics. 343, 2, p. 278-287 10 p.

  Research output: Contribution to journal › Article › peer-review

  • Angiopoietin-2
  • Pseudomonas aeruginosa
  • Sepsis
  • Tumor Necrosis Factor-alpha
  • Neutrophil Infiltration
  16 Scopus citations

• A novel angiopoietin-derived peptide displays anti-angiogenic activity and inhibits tumour-induced and retinal neovascularization

  Palmer, G. M., Tiran, Z., Zhou, Z. Z., Capozzi, M. E., Park, W., Coletta, C., Pyriochou, A., Kliger, Y., Levy, O., Borukhov, I., Dewhirst, M. W., Rotman, G., Penn, J. S. & Papapetropoulos, A., Mar 2012, In: British Journal of Pharmacology. 165, 6, p. 1891-1903 13 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Angiopoietins
  • Retinal Neovascularization
  • Peptides
  • Angiopoietin-2
  • Neoplasms
  10 Scopus citations

• cGMP-Dependent Protein Kinase Contributes to Hydrogen Sulfide-Stimulated Vasorelaxation

  Bucci, M., Papapetropoulos, A., Vellecco, V., Zhou, Z., Zaid, A., Giannogonas, P., Cantalupo, A., Dhayade, S., Karalis, K. P., Wang, R., Feil, R. & Cirino, G., Dec 28 2012, In: PloS one. 7, 12, e53319.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Vasodilation
  • sodium bisulfide
  • cGMP-dependent protein kinase
  • Cyclic GMP-Dependent Protein Kinases
  • Hydrogen Sulfide
  88 Scopus citations

• Hydrogen sulfide and nitric oxide are mutually dependent in the regulation of angiogenesis and endothelium-dependent vasorelaxation

  Coletta, C., Papapetropoulos, A., Erdelyi, K., Olah, G., Módis, K., Panopoulos, P., Asimakopoulou, A., Gerö, D., Sharina, I., Martin, E. & Szabo, C., Jun 5 2012, In: Proceedings of the National Academy of Sciences of the United States of America. 109, 23, p. 9161-9166 6 p.

  Research output: Contribution to journal › Article › peer-review

  • Hydrogen Sulfide
  • Vasodilation
  • Endothelium
  • Guanosine Monophosphate
  • Nitric Oxide
  384 Scopus citations

• Nitric oxide regulates cytokine induction in the diaphragm in response to inspiratory resistive breathing

  Sigala, I., Zacharatos, P., Boulia, S., Toumpanakis, D., Michailidou, T., Parthenis, D., Roussos, C., Papapetropoulos, A., Hussain, S. N. & Vassilakopoulos, T., Nov 15 2012, In: Journal of Applied Physiology. 113, 10, p. 1594-1603 10 p.

  Research output: Contribution to journal › Article › peer-review

  • Diaphragm
  • Research Ethics Committees
  • Respiration
  • NG-Nitroarginine Methyl Ester
  • Nitric Oxide
  16 Scopus citations

• Short-term statin administration in hypercholesterolaemic rabbits resistant to postconditioning: Effects on infarct size, endothelial nitric oxide synthase, and nitro-oxidative stress

  Andreadou, I., Farmakis, D., Prokovas, E., Sigala, F., Zoga, A., Spyridaki, K., Papalois, A., Papapetropoulos, A., Anastasiou-Nana, M., Kremastinos, D. T. & Iliodromitis, E. K., Jun 1 2012, In: Cardiovascular research. 94, 3, p. 501-509 9 p.

  Research output: Contribution to journal › Article › peer-review

  • Pravastatin
  • Nitric Oxide Synthase Type III
  • Hydroxymethylglutaryl-CoA Reductase Inhibitors
  • Simvastatin
  • Oxidative Stress
  49 Scopus citations

• Soluble guanylyl cyclase is a target of angiotensin II-induced nitrosative stress in a hypertensive rat model

  Crassous, P. A., Couloubaly, S., Huang, C., Zhou, Z., Baskaran, P., Kim, D. D., Papapetropoulos, A., Fioramonti, X., Durán, W. N. & Beuve, A., Sep 1 2012, In: American Journal of Physiology - Heart and Circulatory Physiology. 303, 5, p. H597-H604

  Research output: Contribution to journal › Article › peer-review

  • Nitrosative Stress
  • Soluble Guanylyl Cyclase
  • Angiotensin II
  • Nitrosation
  • Nitric Oxide
  29 Scopus citations

• Thioglycine and l-thiovaline: Biologically active H ₂S-donors

  Zhou, Z., Von Wantoch Rekowski, M., Coletta, C., Szabo, C., Bucci, M., Cirino, G., Topouzis, S., Papapetropoulos, A. & Giannis, A., Apr 15 2012, In: Bioorganic and Medicinal Chemistry. 20, 8, p. 2675-2678 4 p.

  Research output: Contribution to journal › Article › peer-review

  • Vasodilation
  • Oxidative stress
  • Gasotransmitters
  • Bicarbonates
  • Acids
  44 Scopus citations
• 2011

  Hydrogen sulfide replacement therapy protects the vascular endothelium in hyperglycemia by preserving mitochondrial function

  Suzuki, K., Olah, G., Modis, K., Coletta, C., Kulp, G., Gerö, D., Szoleczky, P., Chang, T., Zhou, Z., Wu, L., Wang, R., Papapetropoulos, A. & Szabo, C., Aug 16 2011, In: Proceedings of the National Academy of Sciences of the United States of America. 108, 33, p. 13829-13834 6 p.

  Research output: Contribution to journal › Article › peer-review

  • Hydrogen Sulfide
  • Cystathionine
  • Lyases
  • Vascular Endothelium
  • Hyperglycemia
  189 Scopus citations

• Hydrogen sulphide and angiogenesis: Mechanisms and applications

  Szabó, C. & Papapetropoulos, A., Oct 2011, In: British Journal of Pharmacology. 164, 3, p. 853-865 13 p.

  Research output: Contribution to journal › Review article › peer-review

  • Chorioallantoic Membrane
  • Hydrogen Sulfide
  • Chickens
  • Wound Healing
  • Cystathionine gamma-Lyase
  135 Scopus citations

• Inhibition of nitric oxide-stimulated vasorelaxation by carbon monoxide-releasing molecules

  Marazioti, A., Bucci, M., Coletta, C., Vellecco, V., Baskaran, P., Szabó, C., Cirino, G., Marques, A. R., Guerreiro, B., Gonçalves, A. M. L., Seixas, J. D., Beuve, A., Romão, C. C. & Papapetropoulos, A., Nov 2011, In: Arteriosclerosis, thrombosis, and vascular biology. 31, 11, p. 2570-2576 7 p.

  Research output: Contribution to journal › Article › peer-review

  • Carbon Monoxide
  • Vasodilation
  • Nitric Oxide
  • Inhibition (Psychology)
  • Soluble Guanylyl Cyclase
  24 Scopus citations

• MAPKs and NF-κB differentially regulate cytokine expression in the diaphragm in response to resistive breathing: The role of oxidative stress

  Sigala, I., Zacharatos, P., Toumpanakis, D., Michailidou, T., Noussia, O., Theocharis, S., Roussos, C., Papapetropoulos, A. & Vassilakopoulos, T., May 2011, In: American Journal of Physiology - Regulatory Integrative and Comparative Physiology. 300, 5, p. R1152-R1162

  Research output: Contribution to journal › Article › peer-review

  • Diaphragm
  • Respiration
  • Oxidative Stress
  • Cytokines
  • Up-Regulation
  43 Scopus citations

• Mastic oil inhibits the metastatic phenotype of mouse lung adenocarcinoma cells

  Loutrari, H., Magkouta, S., Papapetropoulos, A. & Roussos, C., Mar 2011, In: Cancers. 3, 1, p. 789-801 13 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Adenocarcinoma of Lung
  • Oils
  • Phenotype
  • Pistacia
  • Endothelial Cells
  9 Scopus citations