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  • David Walker
2020
Open Access

Quantitative Proteomics of the Endothelial Secretome Identifies RC0497 as Diagnostic of Acute Rickettsial Spotted Fever Infections

Zhao, Y., Fang, R., Zhang, J., Zhang, Y., Bechelli, J., Smalley, C., Valbuena, G. A., Walker, D. H., Oteo, J. A. & Brasier, A., Feb 2020, In : American Journal of Pathology. 190, 2, p. 306-322 17 p.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations

Recent research milestones in the pathogenesis of human rickettsioses and opportunities ahead

Narra, H. P., Sahni, A., Walker, D. H. & Sahni, S. K., Jun 2020, In : Future Microbiology. 15, 9, p. 753-765 13 p.

Research output: Contribution to journalReview article

The guinea pig model for tick-borne spotted fever rickettsioses: A second look

Stokes, J. V., Walker, D. H. & Varela-Stokes, A. S., Nov 2020, In : Ticks and Tick-borne Diseases. 11, 6, 101538.

Research output: Contribution to journalReview article

Open Access
2019
Open Access
2 Scopus citations

A cluster of cases of rocky mountain spotted fever in an area of Colombia not known to be endemic for this disease

Londoño, A. F., Arango-Ferreira, C., Acevedo-Gutiérrez, L. Y., Paternina, L. E., Montes, C., Ruiz, I., Labruna, M. B., Díaz, F. J., Walker, D. H. & Rodas, J. D., 2019, In : American Journal of Tropical Medicine and Hygiene. 101, 2, p. 336-342 7 p.

Research output: Contribution to journalArticle

2 Scopus citations

Atg5 supports Rickettsia australis infection in macrophages in vitro and in vivo

Bechelli, J., Vergara, L., Smalley, C., Buzhdygan, T. P., Bender, S., Zhang, W., Liu, Y., Popov, V. L., Wang, J., Garg, N., Hwang, S., Walker, D. H. & Fang, R., Jan 1 2019, In : Infection and immunity. 87, 1, e00651.

Research output: Contribution to journalArticle

9 Scopus citations

Burkholderia pseudomallei ΔtonB Δhcp1 live attenuated vaccine strain elicits full protective immunity against aerosolized melioidosis infection

Khakhum, N., Bharaj, P., Myers, J. N., Tapia, D., Kilgore, P. B., Ross, B. N., Walker, D. H., Endsley, J. J. & Torresa, A. G., Jan 1 2019, In : mSphere. 4, 1, e00570-18.

Research output: Contribution to journalArticle

8 Scopus citations

Ehrlichia chaffeensis outer membrane protein 1-specific human antibody-mediated immunity is defined by intracellular TRIM21-dependent innate immune activation and extracellular neutralization

Velayutham, T. S., Kumar, S., Zhang, X., Kose, N., Walker, D. H., Winslow, G., Crowe, J. E. & McBride, J. W., Dec 1 2019, In : Infection and immunity. 87, 12, e00383-19.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations
Open Access
3 Scopus citations
7 Scopus citations

Rickettsiae Within the Fleas of Feral Cats in Galveston, Texas

Blanton, L. S., Vohra, R. F., Fistein, L., Quade, B., Walker, D. H. & Bouyer, D. H., Sep 2019, In : Vector-Borne and Zoonotic Diseases. 19, 9, p. 647-651 5 p.

Research output: Contribution to journalArticle

6 Scopus citations

Seek and you shall find — Unknown pathogens?

Vasilakis, N. & Walker, D. H., May 30 2019, In : New England Journal of Medicine. 380, 22, p. 2174-2175 2 p.

Research output: Contribution to journalComment/debate

Sequelae of Lassa fever: Postviral cerebellar ataxia

Ezeomah, C., Adoga, A., Ihekweazu, C., Paessler, S., Cisneros, I., Tomori, O. & Walker, D., Dec 1 2019, In : Open Forum Infectious Diseases. 6, 12

Research output: Contribution to journalReview article

Open Access
1 Scopus citations

Vector Tick Transmission Model of Spotted Fever Rickettsiosis

Saito, T. B., Bechelli, J., Smalley, C., Karim, S. & Walker, D. H., Jan 2019, In : American Journal of Pathology. 189, 1, p. 115-123 9 p.

Research output: Contribution to journalArticle

3 Scopus citations

Whole-genome sequence of rickettsia parkeri strain atlantic rainforest, isolated from a colombian tick

Londoño, A. F., Mendell, N. L., Valbuena, G. A., Routh, A. L., Wood, T. G., Widen, S. G., Rodas, J. D., Walker, D. H. & Bouyer, D. H., Sep 26 2019, In : Microbiology Resource Announcements. 8, 39, e00684-19.

Research output: Contribution to journalArticle

Open Access
2018
3 Scopus citations

Chlamydial, Mycoplasmal, Rickettsial, and Ehrlichial Diseases

Walker, D. H., Jan 1 2018, Pulmonary Pathology: A Volume in the Series: Foundations in Diagnostic Pathology. Elsevier Inc., p. 315-326 12 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

2017

A review of the global epidemiology of scrub typhus

Xu, G., Walker, D. H., Jupiter, D., Melby, P. C. & Arcari, C. M., Nov 3 2017, In : PLoS neglected tropical diseases. 11, 11, e0006062.

Research output: Contribution to journalArticle

67 Scopus citations

CD8+T cells provide immune protection against murine disseminated endotheliotropic Orientia tsutsugamushi infection

Xu, G., Mendell, N. L., Liang, Y., Shelite, T. R., Goez-Rivillas, Y., Soong, L., Bouyer, D. H. & Walker, D. H., Jul 19 2017, In : PLoS neglected tropical diseases. 11, 7, e0005763.

Research output: Contribution to journalArticle

13 Scopus citations

Fibroblast growth factor receptor-1 mediates internalization of pathogenic spotted fever rickettsiae into host endothelium

Sahni, A., Patel, J., Narra, H. P., Schroeder, C. L. C., Walker, D. H. & Sahni, S. K., Aug 2017, In : PloS one. 12, 8, e0183181.

Research output: Contribution to journalArticle

6 Scopus citations

Flea-Borne Rickettsioses and Rickettsiae

Blanton, L. S. & Walker, D. H., Jan 2017, In : American Journal of Tropical Medicine and Hygiene. 96, 1, p. 53-56 4 p.

Research output: Contribution to journalReview article

28 Scopus citations

Genotypic characterization of Orientia tsutsugamushi from patients in two geographical locations in Sri Lanka

Premaratna, R., Blanton, L. S., Samaraweera, D. N., de Silva, G. N. N., Chandrasena, N. T. G. A., Walker, D. H. & de Silva, H. J., Jan 13 2017, In : BMC Infectious Diseases. 17, 1, 67.

Research output: Contribution to journalArticle

6 Scopus citations

Mechanisms of immunity to rickettsia and implications for vaccine development

Walker, D., Jan 1 2017, In : Revista Colombiana de Ciencias Pecuarias. 30, p. 262-263 2 p.

Research output: Contribution to journalArticle

Murine models of scrub typhus associated with host control of Orientia tsutsugamushi infection

Mendell, N. L., Bouyer, D. H. & Walker, D. H., Mar 10 2017, In : PLoS neglected tropical diseases. 11, 3, e0005453.

Research output: Contribution to journalArticle

9 Scopus citations

Rickettsiae as Emerging Infectious Agents

Fang, R., Blanton, L. S. & Walker, D. H., Jun 2017, In : Clinics in Laboratory Medicine. 37, 2, p. 383-400 18 p.

Research output: Contribution to journalReview article

24 Scopus citations

Time to Worry about Anthrax Again

Keim, P. S., Walker, D. & Zilinskas, R. A., Mar 14 2017, In : Scientific American. 316, 4, p. 70-75 6 p.

Research output: Contribution to journalArticle

2016

An Intradermal Inoculation Mouse Model for Immunological Investigations of Acute Scrub Typhus and Persistent Infection

Soong, L., Mendell, N. L., Olano, J. P., Rockx-Brouwer, D., Xu, G., Goez-Rivillas, Y., Drom, C., Shelite, T. R., Valbuena, G., Walker, D. H. & Bouyer, D. H., Aug 1 2016, In : PLoS neglected tropical diseases. 10, 8, e0004884.

Research output: Contribution to journalArticle

14 Scopus citations

Editorial: Changing dynamics of human-rickettsial interactions

Walker, D. H., Jan 2016, In : American Journal of Tropical Medicine and Hygiene. 94, 1, p. 3-4 2 p.

Research output: Contribution to journalEditorial

5 Scopus citations

Ehrlichioses: An important one health opportunity

Saito, T. B. & Walker, D. H., Sep 1 2016, In : Veterinary Sciences. 3, 3, 20.

Research output: Contribution to journalReview article

9 Scopus citations

Endothelial Activation and Injury: The Mechanisms of Rickettsial Vasculiti

Sahni, A., Narra, H. P., Walker, D. H. & Sahni, S. K., Jan 1 2016, Vascular Responses to Pathogens. Elsevier Inc., p. 111-122 12 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

4 Scopus citations
9 Scopus citations

Epidemiology, molecular biology, and pathogenic mechanisms of Ehrlichia infections

Yu, X. J. & Walker, D., Jan 1 2016, Rickettsiales: Biology, Molecular Biology, Epidemiology, and Vaccine Development. Springer International Publishing, p. 225-240 16 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

1 Scopus citations

Fatal monocytic ehrlichiosis in woman, Mexico, 2013

Sosa-Gutierrez, C. G., Solorzano-Santos, F., Walker, D. H., Torres, J., Serrano, C. A. & Gordillo-Perez, G., May 2016, In : Emerging infectious diseases. 22, 5, p. 871-874 4 p.

Research output: Contribution to journalArticle

7 Scopus citations

MyD88 mediates instructive signaling in dendritic cells and protective inflammatory response during rickettsial infection

Bechelli, J., Smalley, C., Zhao, X., Judy, B., Valdes, P., Walker, D. H. & Fang, R., Apr 1 2016, In : Infection and immunity. 84, 4, p. 883-893 11 p.

Research output: Contribution to journalArticle

12 Scopus citations

Opossums and cat fleas: New insights in the ecology of murine typhus in Galveston, Texas

Blanton, L. S., Idowu, B. M., Tatsch, T. N., Henderson, J. M., Bouyer, D. H. & Walker, D. H., Aug 2016, In : American Journal of Tropical Medicine and Hygiene. 95, 2, p. 457-461 5 p.

Research output: Contribution to journalArticle

27 Scopus citations

Rickettsia

Walker, D., Oct 6 2016, International Encyclopedia of Public Health. Elsevier Inc., p. 370-377 8 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Rickettsia australis activates inflammasome in human and murine macrophages

Smalley, C., Bechelli, J., Rockx-Brouwer, D., Saito, T., Azar, S. R., Ismail, N., Walker, D. H. & Fang, R., Jun 2016, In : PloS one. 11, 6, e0157231.

Research output: Contribution to journalArticle

13 Scopus citations

Scrub typhus - Scientific neglect, ever-widening impact

Walker, D., Sep 8 2016, In : New England Journal of Medicine. 375, 10, p. 913-915 3 p.

Research output: Contribution to journalShort survey

32 Scopus citations
6 Scopus citations
2015

An animal model of a newly emerging human ehrlichiosis

Saito, T. B., Thirumalapura, N. R., Shelite, T. R., Rockx-Brouwer, D., Popov, V. L. & Walker, D. H., Feb 1 2015, In : Journal of Infectious Diseases. 211, 3, p. 452-461 10 p.

Research output: Contribution to journalArticle

13 Scopus citations

A Tick Vector Transmission Model of Monocytotropic Ehrlichiosis

Saito, T. B. & Walker, D. H., Sep 15 2015, In : Journal of Infectious Diseases. 212, 6, p. 968-977 10 p.

Research output: Contribution to journalArticle

12 Scopus citations
7 Scopus citations

Fever and rash after a safari

Damavandy, A. A., Rojek, N. W., Dugan, E. M., Walker, D. & Norton, S. A., Jan 1 2015, In : Journal of the American Academy of Dermatology. 72, 1, p. e5-e6

Research output: Contribution to journalArticle

Permissive and protective roles for neutrophils in leishmaniasis

Carlsen, E. D., Liang, Y., Shelite, T. R., Walker, D. H., Melby, P. C. & Soong, L., Nov 2015, In : Clinical and Experimental Immunology. 182, 2, p. 109-18 10 p.

Research output: Contribution to journalArticle

30 Scopus citations

Reemergence of murine typhus in galveston, texas, usa, 2013

Blanton, L. S., Vohra, R. F., Bouyer, D. H. & Walker, D. H., 2015, In : Emerging infectious diseases. 21, 3, p. 484-486 3 p.

Research output: Contribution to journalArticle

23 Scopus citations

Rickettsia massiliae and rickettsia conorii israeli spotted fever strain differentially regulate endothelial cell responses

Bechelli, J., Smalley, C., Milhano, N., Walker, D. H. & Fang, R., Sep 22 2015, In : PloS one. 10, 9, e0138830.

Research output: Contribution to journalArticle

5 Scopus citations