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• 2019

  Analysis of glucose-derived amino acids involved in one-carbon and cancer metabolism by stable-isotope tracing gas chromatography mass spectrometry

  Sowers, M. L., Herring, J., Zhang, W., Tang, H., Ou, Y., Gu, W. & Zhang, K., Feb 1 2019, In: Analytical Biochemistry. 566, p. 1-9 9 p.

  Research output: Contribution to journal › Article › peer-review

  • Mass spectrometry
  • Metabolism
  • Gas chromatography
  • Gas Chromatography-Mass Spectrometry
  • Isotopes
  6 Scopus citations

• A unique role of carboxylesterase 3 (CES3) in b-adrenergic signaling–stimulated thermogenesis

  Yang, L., Li, X., Tang, H., Gao, Z., Zhang, K. & Sun, K., Jun 1 2019, In: Diabetes. 68, 6, p. 1178-1196 19 p.

  Research output: Contribution to journal › Article › peer-review

  • Carboxylesterase
  • Thermogenesis
  • Adrenergic Agents
  • Adipose Tissue
  • Isoproterenol
  7 Scopus citations

• Sex-specific proteomic changes induced by genetic deletion of fibroblast growth factor 14 (FGF14), a regulator of neuronal ion channels

  Sowers, M. L., Di Re, J., Wadsworth, P. A., Shavkunov, A. S., Lichti, C., Zhang, K. & Laezza, F., Mar 1 2019, In: Proteomes. 7, 1, 5.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • fibroblast growth factor 14
  • Proteomics
  • Ion Channels
  • Schizophrenia
  • Proteome
  5 Scopus citations
• 2016

  Acetylome study in mouse adipocytes identifies targets of SIRT1 deacetylation in chromatin organization and RNA processing

  Kim, S. Y., Sim, C. K., Tang, H., Han, W., Zhang, K. & Xu, F., May 15 2016, In: Archives of Biochemistry and Biophysics. 598, p. 1-10 10 p.

  Research output: Contribution to journal › Article › peer-review

  • Adipocytes
  • Chromatin
  • RNA
  • Metabolism
  • Lysine
  7 Scopus citations

• An alternative strategy for pan-acetyl-lysine antibody generation

  Kim, S. Y., Sim, C. K., Zhang, Q., Tang, H., Brunmeir, R., Pan, H., Karnani, N., Han, W., Zhang, K. & Xu, F., Sep 2016, In: PloS one. 11, 9, e0162528.

  Research output: Contribution to journal › Article › peer-review

  • Lysine
  • lysine
  • antibodies
  • Antibodies
  • Peptides
  3 Scopus citations

• Measurement of Histone Methylation Dynamics by One-Carbon Metabolic Isotope Labeling and High-energy Collisional Dissociation Methylation Signature Ion Detection

  Tang, H., Tian, B., Brasier, A. R., Sowers, L. C. & Zhang, K., Aug 17 2016, In: Scientific reports. 6, 31537.

  Research output: Contribution to journal › Article › peer-review

  • Carbon Isotopes
  • Isotope Labeling
  • Histones
  • Methylation
  • Ions
  3 Scopus citations
• 2015

  Acetylome analysis identifies SIRT1 targets in mRNA-processing and chromatin-remodeling in mouse liver

  Kim, S. Y., Sim, C. K., Tang, H., Han, W., Zhang, K. & Xu, F., Oct 15 2015, In: PloS one. 10, 10, e0140619.

  Research output: Contribution to journal › Article › peer-review

  • Sirtuin 1
  • Liver
  • Chromatin Assembly and Disassembly
  • chromatin
  • Chromatin
  8 Scopus citations

• Induction of indoleamine 2, 3-dioxygenase in human dendritic cells by a cholera toxin B subunit- Proinsulin vaccine

  Mbongue, J. C., Nicholas, D. A., Zhang, K., Kim, N. S., Hamilton, B. N., Larios, M., Zhang, G., Umezawa, K., Firek, A. F. & Langridge, W. H. R., Feb 25 2015, In: PloS one. 10, 2, e0118562.

  Research output: Contribution to journal › Article › peer-review

  • indoleamine 2,3-dioxygenase
  • Dendritic Cells
  • proinsulin
  • Indoleamine-Pyrrole 2,3,-Dioxygenase
  • Proinsulin
  19 Scopus citations

• Measurement of Postreplicative DNA Metabolism and Damage in the Rodent Brain

  Patel, J. P., Sowers, M. L., Herring, J. L., Theruvathu, J. A., Emmett, M. R., Hawkins, B. E., Zhang, K., Dewitt, D. S., Prough, D. S. & Sowers, L. C., Dec 21 2015, In: Chemical Research in Toxicology. 28, 12, p. 2352-2363 12 p.

  Research output: Contribution to journal › Article › peer-review

  • Metabolism
  • DNA Damage
  • Brain
  • Rodentia
  • DNA
  5 Scopus citations

• Quantification of Histone Modifications by Parallel-Reaction Monitoring: A Method Validation

  Sowers, J. L., Mirfattah, B., Xu, P., Tang, H., Park, I. Y., Walker, C., Wu, P., Laezza, F., Sowers, L. C. & Zhang, K., Oct 6 2015, In: Analytical Chemistry. 87, 19, p. 10006-10014 9 p.

  Research output: Contribution to journal › Article › peer-review

  • Histones
  • Monitoring
  • Acetylation
  • Methylation
  • Ascorbic Acid
  18 Scopus citations

• Quantitative proteomics reveals a role for epigenetic reprogramming during human monocyte differentiation

  Nicholas, D., Tang, H., Zhang, Q., Rudra, J., Xu, F., Langridge, W. & Zhang, K., Jan 1 2015, In: Molecular and Cellular Proteomics. 14, 1, p. 15-29 15 p.

  Research output: Contribution to journal › Article › peer-review

  • Proteomics
  • Macrophages
  • Dendritic Cells
  • Histones
  • Epigenomics
  19 Scopus citations
• 2014

  Cellular levels of oxidative stress affect the response of cervical cancer cells to chemotherapeutic agents

  Filippova, M., Filippov, V., Williams, V. M., Zhang, K., Kokoza, A., Bashkirova, S. & Duerksen-Hughes, P., 2014, In: BioMed Research International. 2014, 574659.

  Research output: Contribution to journal › Article › peer-review

  • Oxidative stress
  • Cells
  • Uterine Cervical Neoplasms
  • Oxidative Stress
  • Doxorubicin
  34 Scopus citations

• Down-regulation of LXR/RXR activation and negative acute phase response pathways in colon adenocarcinoma revealed by proteomics and bioinformatics analysis

  Tang, H., Mirshahidi, S., Senthil, M., Kazanjian, K., Chen, C. S. & Zhang, K., 2014, In: Cancer Biomarkers. 14, 5, p. 313-324 12 p.

  Research output: Contribution to journal › Article › peer-review

  • Acute-Phase Reaction
  • Computational Biology
  • Proteomics
  • Colon
  • Adenocarcinoma
  13 Scopus citations

• Inhibition of DNA methylation reverses norepinephrine-induced cardiac hypertrophy in rats

  Xiao, D., Dasgupta, C., Chen, M., Zhang, K., Buchholz, J., Xu, Z. & Zhang, L., Mar 1 2014, In: Cardiovascular research. 101, 3, p. 373-382 10 p.

  Research output: Contribution to journal › Article › peer-review

  • DNA Methylation
  • Norepinephrine
  • Decitabine
  • Heart
  • Demethylation
  62 Scopus citations

• Multiplexed parallel reaction monitoring targeting histone modifications on the QExactive mass spectrometer

  Tang, H., Fang, H., Yin, E., Brasier, A. R., Sowers, L. C. & Zhang, K., Jun 3 2014, In: Analytical Chemistry. 86, 11, p. 5526-5534 9 p.

  Research output: Contribution to journal › Article › peer-review

  • Mass spectrometers
  • Acetylation
  • Histones
  • Methylation
  • Monitoring
  44 Scopus citations

• Proteome analysis of coinfection of epithelial cells with Filifactor alocis and Porphyromonas gingivalis shows modulation of pathogen and host regulatory pathways

  Aruni, A. W., Zhang, K., Dou, Y. & Fletcher, H., 2014, In: Infection and immunity. 82, 8, p. 3261-3274 14 p.

  Research output: Contribution to journal › Article › peer-review

  • Porphyromonas gingivalis
  • Proteome
  • Coinfection
  • Epithelial Cells
  • Proteins
  18 Scopus citations
• 2011

  Differential histone modification and protein expression associated with cell wall removal and regeneration in rice (Oryza sativa)

  Tan, F., Zhang, K., Mujahid, H., Verma, D. P. S. & Peng, Z., Feb 4 2011, In: Journal of Proteome Research. 10, 2, p. 551-563 13 p.

  Research output: Contribution to journal › Article › peer-review

  • Oryza
  • Histone Code
  • Cell Wall
  • Cells
  • Histones
  20 Scopus citations

• Mass spectrometric studies on epigenetic interaction networks in cell differentiation

  Xiong, L., Darwanto, A., Sharma, S., Herring, J., Hu, S., Filippova, M., Filippov, V., Wang, Y., Chen, C. S., Duerksen-Hughes, P. J., Sowers, L. C. & Zhang, K., Apr 15 2011, In: Journal of Biological Chemistry. 286, 15, p. 13657-13668 12 p.

  Research output: Contribution to journal › Article › peer-review

  • Histones
  • Epigenomics
  • Cell Differentiation
  • RNA Polymerase II
  • Ubiquitination
  21 Scopus citations

• Quantification of ceramide levels in mammalian cells by high performance liquid chromatography coupled to tandem mass spectrometry with multiple-reaction-monitoring mode (HPLC-MS/MS-MRM)

  Zhang, K., Haynes, T. A. S., Filippova, M., Filippov, V. & Duerksen-Hughes, P. J., May 1 2011, In: Analytical Methods. 3, 5, p. 1193-1197 5 p.

  Research output: Contribution to journal › Article › peer-review

  • Ceramides
  • High performance liquid chromatography
  • Mass spectrometry
  • Cells
  • Monitoring
  10 Scopus citations

• Tet-mediated formation of 5-carboxylcytosine and its excision by TDG in mammalian DNA

  He, Y. F., Li, B. Z., Li, Z., Liu, P., Wang, Y., Tang, Q., Ding, J., Jia, Y., Chen, Z., Li, N., Sun, Y., Li, X., Dai, Q., Song, C. X., Zhang, K., He, C. & Xu, G. L., Sep 2 2011, In: Science. 333, 6047, p. 1303-1307 5 p.

  Research output: Contribution to journal › Article › peer-review

  • 5-carboxylcytosine
  • Thymine DNA Glycosylase
  • 5-Methylcytosine
  • 5-hydroxymethylcytosine
  • Dioxygenases
  1661 Scopus citations