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• 2013

  Dual role of p53 amyloid formation in cancer; loss of function and gain of toxicity

  Lasagna-Reeves, C. A., Clos, A. L., Castillo-Carranza, D., Sengupta, U., Guerrero-Muñoz, M., Kelly, B., Wagner, R. & Kayed, R., Jan 18 2013, In: Biochemical and Biophysical Research Communications. 430, 3, p. 963-968 6 p.

  Research output: Contribution to journal › Article › peer-review

  • Toxicity
  • Amyloid
  • Oligomers
  • Conformations
  • Neoplasms
  53 Scopus citations

• Formation and propagation of tau oligomeric seeds

  Gerson, J. E. & Kayed, R., Sep 11 2013, In: Frontiers in Neurology. 4 JUL, Article 93.

  Research output: Contribution to journal › Review article › peer-review

  • Seeds
  • Tauopathies
  • Neurofibrillary Tangles
  • Poisons
  • Exocytosis
  67 Scopus citations

• Molecular mechanisms of amyloid oligomers toxicity

  Kayed, R. & Lasagna-Reeves, C. A., Feb 15 2013, Alzheimer's Disease: Advances for a New Century. IOS Press, p. 67-78 12 p.

  Research output: Chapter in Book/Report/Conference proceeding › Chapter

  • Amyloid
  • Amyloid Plaques
  • Cell Death
  • Poisons
  • Memory
  2 Scopus citations

• Molecular mechanisms of amyloid oligomers toxicity

  Kayed, R. & Lasagna-Reeves, C. A., 2013, In: Journal of Alzheimer's Disease. 33, SUPPL. 1, p. S67-S78

  Research output: Contribution to journal › Review article › peer-review

  • Amyloid
  • Amyloid Plaques
  • Cell Death
  • Poisons
  • Memory
  212 Scopus citations

• Rapid accumulation of endogenous Tau oligomers in a rat model of traumatic brain injury: Possible link between traumatic brain injury and sporadic tauopathies

  Hawkins, B. E., Krishnamurthy, S., Castillo-Carranza, D. L., Sengupta, U., Prough, D. S., Jackson, G. R., DeWitt, D. S. & Kayed, R., Jun 7 2013, In: Journal of Biological Chemistry. 288, 23, p. 17042-17050 9 p.

  Research output: Contribution to journal › Article › peer-review

  • Oligomers
  • Tauopathies
  • Rats
  • Traumatic Brain Injury
  • Brain
  90 Scopus citations

• Small misfolded tau species are internalized via bulk endocytosis and anterogradely and retrogradely transported in neurons

  Wu, J. W., Herman, M., Liu, L., Simoes, S., Acker, C. M., Figueroa, H., Steinberg, J. I., Margittai, M., Kayed, R., Zurzolo, C., Di Paolo, G. & Duff, K. E., Jan 18 2013, In: Journal of Biological Chemistry. 288, 3, p. 1856-1870 15 p.

  Research output: Contribution to journal › Article › peer-review

  • Endocytosis
  • Neurons
  • Tauopathies
  • Conformations
  • Molecular weight
  278 Scopus citations

• Tau aggregates as immunotherapeutic targets

  Castillo-Carranza, D. L., Lasagna-Reeves, C. A. & Kayed, R., Jan 1 2013, In: Frontiers in Bioscience - Scholar. 5 S, 2, p. 426-438 13 p.

  Research output: Contribution to journal › Article › peer-review

  • Oligomers
  • Neurofibrillary Tangles
  • Toxicity
  • Tauopathies
  • Neurodegenerative diseases
  30 Scopus citations
• 2011

  Amyloid-β annular protofibrils evade fibrillar fate in Alzheimer disease brain

  Lasagna-Reeves, C. A., Glabe, C. G. & Kayed, R., Jun 24 2011, In: Journal of Biological Chemistry. 286, 25, p. 22122-22130 9 p.

  Research output: Contribution to journal › Article › peer-review

  • Amyloid
  • Brain
  • Alzheimer Disease
  • Toxicity
  • In Vitro Techniques
  101 Scopus citations

• ApoE4-driven accumulation of intraneuronal oligomerized Aß42 following activation of the amyloid cascade in vivo is mediated by a gain of function

  Zepa, L., Frenkel, M., Belinson, H., Kariv-Inbal, Z., Kayed, R., Masliah, E. & Michaelson, D. M., 2011, In: International Journal of Alzheimer's Disease. 792070.

  Research output: Contribution to journal › Article › peer-review

  • Apolipoprotein E4
  • Amyloid
  • Apolipoprotein E3
  • Apolipoproteins E
  • Neprilysin
  21 Scopus citations

• Astrocytes contain amyloid-β annular protofibrils in Alzheimer's disease brains

  Lasagna-Reeves, C. A. & Kayed, R., Oct 3 2011, In: FEBS Letters. 585, 19, p. 3052-3057 6 p.

  Research output: Contribution to journal › Article › peer-review

  • Astrocytes
  • Amyloid
  • Brain
  • Alzheimer Disease
  • Conformations
  28 Scopus citations

• Formation of immunoglobulin light chain amyloid oligomers in primary cutaneous nodular amyloidosis

  Clos, A. L., Lasagna-Reeves, C. A., Castillo-Carranza, D. L., Sengupta, U., Jackson, G. R., Kelly, B., Beachkofsky, T. M. & Kayed, R., Dec 1 2011, In: British Journal of Dermatology. 165, 6, p. 1349-1354 6 p.

  Research output: Contribution to journal › Article › peer-review

  • Primary Cutaneous Amyloidosis
  • Immunoglobulin Light Chains
  • Amyloid
  • Immunoglobulins
  • Keratinocytes
  12 Scopus citations

• Role of oligomers in the amyloidogenesis of primary cutaneous amyloidosis

  Clos, A. L., Lasagna-Reeves, C. A., Kelly, B., Wagner, R., Wilkerson, M., Jackson, G. R. & Kayed, R., Nov 1 2011, In: Journal of the American Academy of Dermatology. 65, 5, p. 1023-1031 9 p.

  Research output: Contribution to journal › Article › peer-review

  • Primary Cutaneous Amyloidosis
  • Amyloid
  • Skin
  • antibiotic I-11
  • thioflavin T
  10 Scopus citations

• Tau oligomers as potential targets for immunotherapy for alzheimer's disease and tauopathies

  Lasagna-Reeves, C. A., Castillo-Carranza, D. L., Jackson, G. R. & Kayed, R., Sep 1 2011, In: Current Alzheimer Research. 8, 6, p. 659-665 7 p.

  Research output: Contribution to journal › Article › peer-review

  • Tauopathies
  • Immunotherapy
  • Alzheimer Disease
  • Neurofibrillary Tangles
  • tau Proteins
  57 Scopus citations

• Tau oligomers impair memory and induce synaptic and mitochondrial dysfunction in wild-type mice

  Lasagna-Reeves, C. A., Castillo-Carranza, D. L., Sengupta, U., Clos, A. L., Jackson, G. R. & Kayed, R., 2011, In: Molecular Neurodegeneration. 6, 1, 39.

  Research output: Contribution to journal › Article › peer-review

  • Electron Transport Complex I
  • Tauopathies
  • human MAPT protein
  • Alzheimer Disease
  • Septins
  278 Scopus citations