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2020
Activation of ASC Inflammasome Driven by Toll-Like Receptor 4 Contributes to Host Immunity against Rickettsial Infection
Rumfield, C., Hyseni, I., McBride, J. W., Walker, D. H. & Fang, R., Mar 23 2020, In: Infection and immunity. 88, 4Research output: Contribution to journal › Article › peer-review
1 Scopus citations -
A single mutation (V64G) within the ring domain of Z attenuates junin virus
Hallam, S. J., Manning, J. T., Maruyama, J., Seregin, A., Huang, C., Walker, D. H., de la Torre, J. C. & Paessler, S., Sep 2020, In: PLoS neglected tropical diseases. 14, 9, p. 1-15 15 p., e0008555.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations -
Ehrlichia chaffeensis and E. canis hypothetical protein immunoanalysis reveals small secreted immunodominant proteins and conformation-dependent antibody epitopes
Luo, T., Patel, J. G., Zhang, X., Walker, D. H. & McBride, J. W., Dec 1 2020, In: npj Vaccines. 5, 1, 85.Research output: Contribution to journal › Article › peer-review
Open Access -
Human monocytic ehrlichiosis, Mexico City, Mexico
Alcántara-Rodríguez, V. E., Sánchez-Montes, S., Contreras, H., Colunga-Salas, P., Fierro-Flores, L., Avalos, S., Rodríguez-Rangel, F., Becker, I. & Walker, D. H., Dec 2020, In: Emerging infectious diseases. 26, 12, p. 3016-3019 4 p.Research output: Contribution to journal › Article › peer-review
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Human rickettsiosis caused by rickettsia parkeri strain Atlantic rainforest, Urabá, Colombia
Arboleda, M., Acevedo-Gutiérrez, L. Y., Ávila, A., Ospina, D., Díaz, F. J., Walker, D. H. & Rodas, J. D., Dec 2020, In: Emerging infectious diseases. 26, 12, p. 3048-3050 3 p.Research output: Contribution to journal › Article › peer-review
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Perspective Piece: Ideal Criteria for Accurate Mouse Models of Vector-Borne Diseases with Emphasis on Scrub Typhus and Dengue
Sarathy, V. V. & Walker, D. H., Sep 2020, In: American Journal of Tropical Medicine and Hygiene. 103, 3, p. 970-975 6 p.Research output: Contribution to journal › Review article › peer-review
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Quantitative Proteomics of the Endothelial Secretome Identifies RC0497 as Diagnostic of Acute Rickettsial Spotted Fever Infections
Zhao, Y., Fang, R., Zhang, J., Zhang, Y., Bechelli, J., Smalley, C., Valbuena, G., Walker, D. H., Oteo, J. A. & Brasier, A. R., Feb 2020, In: American Journal of Pathology. 190, 2, p. 306-322 17 p.Research output: Contribution to journal › Article › peer-review
Open Access3 Scopus citations -
Recent research milestones in the pathogenesis of human rickettsioses and opportunities ahead
Narra, H. P., Sahni, A., Walker, D. H. & Sahni, S. K., Jun 2020, In: Future Microbiology. 15, 9, p. 753-765 13 p.Research output: Contribution to journal › Review article › peer-review
1 Scopus citations -
The guinea pig model for tick-borne spotted fever rickettsioses: A second look
Stokes, J. V., Walker, D. H. & Varela-Stokes, A. S., Nov 2020, In: Ticks and Tick-borne Diseases. 11, 6, 101538.Research output: Contribution to journal › Review article › peer-review
Open Access -
2019
A biosafety level-2 dose-dependent lethal mouse model of spotted fever rickettsiosis: Rickettsia parkeri atlantic rainforest strain
Londoño, A. F., Mendell, N. L., Walker, D. H. & Bouyer, D. H., Jun 2019, In: PLoS neglected tropical diseases. 13, 6, e0007054.Research output: Contribution to journal › Article › peer-review
Open Access2 Scopus citations -
A cluster of cases of rocky mountain spotted fever in an area of Colombia not known to be endemic for this disease
Londoño, A. F., Arango-Ferreira, C., Acevedo-Gutiérrez, L. Y., Paternina, L. E., Montes, C., Ruiz, I., Labruna, M. B., Díaz, F. J., Walker, D. H. & Rodas, J. D., 2019, In: American Journal of Tropical Medicine and Hygiene. 101, 2, p. 336-342 7 p.Research output: Contribution to journal › Article › peer-review
2 Scopus citations -
Atg5 supports Rickettsia australis infection in macrophages in vitro and in vivo
Bechelli, J., Vergara, L., Smalley, C., Buzhdygan, T. P., Bender, S., Zhang, W., Liu, Y., Popov, V. L., Wang, J., Garg, N., Hwang, S., Walker, D. H. & Fang, R., Jan 1 2019, In: Infection and immunity. 87, 1, e00651.Research output: Contribution to journal › Article › peer-review
10 Scopus citations -
Burkholderia pseudomallei ΔtonB Δhcp1 live attenuated vaccine strain elicits full protective immunity against aerosolized melioidosis infection
Khakhum, N., Bharaj, P., Myers, J. N., Tapia, D., Kilgore, P. B., Ross, B. N., Walker, D. H., Endsley, J. J. & Torresa, A. G., Jan 1 2019, In: mSphere. 4, 1, e00570-18.Research output: Contribution to journal › Article › peer-review
11 Scopus citations -
Ehrlichia chaffeensis outer membrane protein 1-specific human antibody-mediated immunity is defined by intracellular TRIM21-dependent innate immune activation and extracellular neutralization
Velayutham, T. S., Kumar, S., Zhang, X., Kose, N., Walker, D. H., Winslow, G., Crowe, J. E. & McBride, J. W., Dec 1 2019, In: Infection and immunity. 87, 12, e00383-19.Research output: Contribution to journal › Article › peer-review
Open Access4 Scopus citations -
Evaluation of Burkholderia mallei ΔtonB Δhcp1 (CLH001) as a live attenuated vaccine in murine models of glanders and melioidosis
Khakhum, N., Bharaj, P., Myers, J. N., Tapia, D., Walker, D. H., Endsley, J. J. & Torres, A. G., Jul 2019, In: PLoS neglected tropical diseases. 13, 7, e0007578.Research output: Contribution to journal › Article › peer-review
Open Access5 Scopus citations -
Pathogenesis of Rickettsial Diseases: Pathogenic and Immune Mechanisms of an Endotheliotropic Infection
Sahni, A., Fang, R., Sahni, S. K. & Walker, D. H., 2019, In: Annual Review of Pathology: Mechanisms of Disease. 14, p. 127-152 26 p.Research output: Contribution to journal › Article › peer-review
13 Scopus citations -
Rickettsiae Within the Fleas of Feral Cats in Galveston, Texas
Blanton, L. S., Vohra, R. F., Fistein, L., Quade, B., Walker, D. H. & Bouyer, D. H., Sep 2019, In: Vector-Borne and Zoonotic Diseases. 19, 9, p. 647-651 5 p.Research output: Contribution to journal › Article › peer-review
7 Scopus citations -
Seek and you shall find — Unknown pathogens?
Vasilakis, N. & Walker, D. H., May 30 2019, In: New England Journal of Medicine. 380, 22, p. 2174-2175 2 p.Research output: Contribution to journal › Comment/debate › peer-review
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Sequelae of Lassa fever: Postviral cerebellar ataxia
Ezeomah, C., Adoga, A., Ihekweazu, C., Paessler, S., Cisneros, I., Tomori, O. & Walker, D., Dec 1 2019, In: Open Forum Infectious Diseases. 6, 12Research output: Contribution to journal › Review article › peer-review
Open Access1 Scopus citations -
Susceptibility of Rickettsia rickettsii to Tigecycline in a Cell Culture Assay and Animal Model for Rocky Mountain Spotted Fever
Blanton, L. S., Wilson, N. M., Quade, B. R. & Walker, D. H., 2019, In: American Journal of Tropical Medicine and Hygiene. 101, 5, p. 1091-1095 5 p.Research output: Contribution to journal › Article › peer-review
2 Scopus citations -
Vector Tick Transmission Model of Spotted Fever Rickettsiosis
Saito, T. B., Bechelli, J., Smalley, C., Karim, S. & Walker, D. H., Jan 2019, In: American Journal of Pathology. 189, 1, p. 115-123 9 p.Research output: Contribution to journal › Article › peer-review
4 Scopus citations -
Whole-genome sequence of rickettsia parkeri strain atlantic rainforest, isolated from a colombian tick
Londoño, A. F., Mendell, N. L., Valbuena, G. A., Routh, A. L., Wood, T. G., Widen, S. G., Rodas, J. D., Walker, D. H. & Bouyer, D. H., Sep 26 2019, In: Microbiology Resource Announcements. 8, 39, e00684-19.Research output: Contribution to journal › Article › peer-review
Open Access -
2018
Analysis of health-Care charges in murine typhus: Need for improved clinical recognition and diagnostics for acute disease
Vohra, R. F., Walker, D. H. & Blanton, L. S., 2018, In: American Journal of Tropical Medicine and Hygiene. 98, 6, p. 1594-1598 5 p.Research output: Contribution to journal › Article › peer-review
5 Scopus citations -
Chlamydial, Mycoplasmal, Rickettsial, and Ehrlichial Diseases
Walker, D. H., 2018, Pulmonary Pathology: A Volume in the Series: Foundations in Diagnostic Pathology. Elsevier Inc., p. 315-326 12 p.Research output: Chapter in Book/Report/Conference proceeding › Chapter
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2017
A review of the global epidemiology of scrub typhus
Xu, G., Walker, D. H., Jupiter, D., Melby, P. C. & Arcari, C. M., Nov 3 2017, In: PLoS neglected tropical diseases. 11, 11, e0006062.Research output: Contribution to journal › Article › peer-review
75 Scopus citations -
CD8+T cells provide immune protection against murine disseminated endotheliotropic Orientia tsutsugamushi infection
Xu, G., Mendell, N. L., Liang, Y., Shelite, T. R., Goez-Rivillas, Y., Soong, L., Bouyer, D. H. & Walker, D. H., Jul 19 2017, In: PLoS neglected tropical diseases. 11, 7, e0005763.Research output: Contribution to journal › Article › peer-review
15 Scopus citations -
Fibroblast growth factor receptor-1 mediates internalization of pathogenic spotted fever rickettsiae into host endothelium
Sahni, A., Patel, J., Narra, H. P., Schroeder, C. L. C., Walker, D. H. & Sahni, S. K., Aug 2017, In: PloS one. 12, 8, e0183181.Research output: Contribution to journal › Article › peer-review
10 Scopus citations -
Flea-Borne Rickettsioses and Rickettsiae
Blanton, L. S. & Walker, D. H., Jan 2017, In: American Journal of Tropical Medicine and Hygiene. 96, 1, p. 53-56 4 p.Research output: Contribution to journal › Review article › peer-review
34 Scopus citations -
Genotypic characterization of Orientia tsutsugamushi from patients in two geographical locations in Sri Lanka
Premaratna, R., Blanton, L. S., Samaraweera, D. N., de Silva, G. N. N., Chandrasena, N. T. G. A., Walker, D. H. & de Silva, H. J., Jan 13 2017, In: BMC Infectious Diseases. 17, 1, 67.Research output: Contribution to journal › Article › peer-review
9 Scopus citations -
Mechanisms of immunity to rickettsia and implications for vaccine development
Walker, D., Jan 1 2017, In: Revista Colombiana de Ciencias Pecuarias. 30, p. 262-263 2 p.Research output: Contribution to journal › Article › peer-review
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Murine models of scrub typhus associated with host control of Orientia tsutsugamushi infection
Mendell, N. L., Bouyer, D. H. & Walker, D. H., Mar 10 2017, In: PLoS neglected tropical diseases. 11, 3, e0005453.Research output: Contribution to journal › Article › peer-review
11 Scopus citations -
Rickettsiae as Emerging Infectious Agents
Fang, R., Blanton, L. S. & Walker, D. H., Jun 2017, In: Clinics in Laboratory Medicine. 37, 2, p. 383-400 18 p.Research output: Contribution to journal › Review article › peer-review
27 Scopus citations -
Time to Worry about Anthrax Again
Keim, P. S., Walker, D. H. & Zilinskas, R. A., Mar 14 2017, In: Scientific American. 316, 4, p. 70-75 6 p.Research output: Contribution to journal › Article › peer-review
1 Scopus citations -
2015
An animal model of a newly emerging human ehrlichiosis
Saito, T. B., Thirumalapura, N. R., Shelite, T. R., Rockx-Brouwer, D., Popov, V. L. & Walker, D. H., Feb 1 2015, In: Journal of Infectious Diseases. 211, 3, p. 452-461 10 p.Research output: Contribution to journal › Article › peer-review
14 Scopus citations -
A Tick Vector Transmission Model of Monocytotropic Ehrlichiosis
Saito, T. B. & Walker, D. H., Sep 15 2015, In: Journal of Infectious Diseases. 212, 6, p. 968-977 10 p.Research output: Contribution to journal › Article › peer-review
14 Scopus citations -
Case report: An unusual cutaneous manifestation in a patient with murine typhus
Blanton, L. S., Lea, A. S., Kelly, B. C. & Walker, D. H., Dec 2015, In: American Journal of Tropical Medicine and Hygiene. 93, 6, p. 1164-1167 4 p.Research output: Contribution to journal › Article › peer-review
9 Scopus citations -
Fever and rash after a safari
Damavandy, A. A., Rojek, N. W., Dugan, E. M., Walker, D. & Norton, S. A., Jan 1 2015, In: Journal of the American Academy of Dermatology. 72, 1, p. e5-e6Research output: Contribution to journal › Article › peer-review
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Permissive and protective roles for neutrophils in leishmaniasis
Carlsen, E. D., Liang, Y., Shelite, T. R., Walker, D. H., Melby, P. C. & Soong, L., Nov 2015, In: Clinical and Experimental Immunology. 182, 2, p. 109-18 10 p.Research output: Contribution to journal › Article › peer-review
32 Scopus citations -
Reemergence of murine typhus in galveston, texas, usa, 2013
Blanton, L. S., Vohra, R. F., Bouyer, D. H. & Walker, D. H., 2015, In: Emerging infectious diseases. 21, 3, p. 484-486 3 p.Research output: Contribution to journal › Article › peer-review
24 Scopus citations -
Rickettsia massiliae and rickettsia conorii israeli spotted fever strain differentially regulate endothelial cell responses
Bechelli, J., Smalley, C., Milhano, N., Walker, D. H. & Fang, R., Sep 22 2015, In: PloS one. 10, 9, e0138830.Research output: Contribution to journal › Article › peer-review
5 Scopus citations -
The role of CD8 T lymphocytes in rickettsial infections
Walker, D. H. & Dumler, J. S., May 26 2015, In: Seminars in Immunopathology. 37, 3, p. 289-299 11 p.Research output: Contribution to journal › Review article › peer-review
17 Scopus citations -
The role of Rhipicephalus sanguineus sensu lato saliva in the dissemination of Rickettsia conorii in C3H/HeJ mice
Milhano, N., Saito, T. B., Bechelli, J., Fang, R., Vilhena, M., De Sousa, R. & Walker, D. H., Sep 1 2015, In: Medical and Veterinary Entomology. 29, 3, p. 225-229 5 p.Research output: Contribution to journal › Article › peer-review
9 Scopus citations -
2013
Approaches to vaccines against Orientia tsutsugamushi
Valbuena, G. & Walker, D. H., 2013, In: Frontiers in cellular and infection microbiology. 4, JAN, Article 170.Research output: Contribution to journal › Article › peer-review
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Approaches to vaccines against Orientia tsutsugamushi
Valbuena, G. & Walker, D. H., 2013, In: Frontiers in Cellular and Infection Microbiology. 4, JAN, Article 170.Research output: Contribution to journal › Review article › peer-review
Open Access45 Scopus citations -
Case-Fatality ratio and effectiveness of ribavirin therapy among hospitalized patients in china who had severe fever with thrombocytopenia syndrome
Liu, W., Lu, Q. B., Cui, N., Li, H., Wang, L. Y., Liu, K., Yang, Z. D., Wang, B. J., Wang, H. Y., Zhang, Y. Y., Zhuang, L., Hu, C. Y., Yuan, C., Fan, X. J., Wang, Z., Zhang, L., Zhang, X. A., Walker, D. H. & Cao, W. C., Nov 1 2013, In: Clinical Infectious Diseases. 57, 9, p. 1292-1299 8 p.Research output: Contribution to journal › Article › peer-review
100 Scopus citations -
Compartmentalized, functional role of angiogenin during spotted fever group rickettsia-induced endothelial barrier dysfunction: Evidence of possible mediation by host tRNA-derived small noncoding RNAs
Gong, B., Lee, Y. S., Lee, I., Shelite, T. R., Kunkeaw, N., Xu, G., Lee, K., Jeon, S. H., Johnson, B. H., Chang, Q., Ha, T., Mendell, N. L., Cheng, X., Bouyer, D. H., Boor, P. J., Ksiazek, T. G. & Walker, D. H., Jun 23 2013, In: BMC Infectious Diseases. 13, 1, 285.Research output: Contribution to journal › Article › peer-review
27 Scopus citations -
Exchange protein directly activated by cAMP plays a critical role in bacterial invasion during fatal rickettsioses
Gong, B., Shelite, T., Mei, F. C., Ha, T., Hu, Y., Xu, G., Chang, Q., Wakamiya, M., Ksiazek, T. G., Boor, P. J., Bouyer, D. H., Popov, V. L., Chen, J., Walker, D. H. & Cheng, X., Nov 26 2013, In: Proceedings of the National Academy of Sciences of the United States of America. 110, 48, p. 19615-19620 6 p.Research output: Contribution to journal › Article › peer-review
49 Scopus citations -
Mice lacking functional STAT1 are highly susceptible to lethal infection with Lassa virus
Yun, N. E., Seregin, A. V., Walker, D. H., Popov, V. L., Walker, A. G., Smith, J. N., Miller, M., de la Torre, J. C., Smith, J. K., Borisevich, V., Fair, J. N., Wauquier, N., Grant, D. S., Bockarie, B., Bente, D. & Paessler, S., 2013, In: Journal of virology. 87, 19, p. 10908-10911 4 p.Research output: Contribution to journal › Article › peer-review
34 Scopus citations -
Pathogenesis of the viral hemorrhagic fevers
Paessler, S. & Walker, D. H., Jan 2013, In: Annual Review of Pathology: Mechanisms of Disease. 8, p. 411-440 30 p.Research output: Contribution to journal › Review article › peer-review
160 Scopus citations -
Recent molecular insights into rickettsial pathogenesis and immunity
Sahni, S. K., Narra, H. P., Sahni, A. & Walker, D. H., Oct 2013, In: Future Microbiology. 8, 10, p. 1265-1288 24 p.Research output: Contribution to journal › Review article › peer-review
59 Scopus citations