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2020
Activation of ASC Inflammasome Driven by Toll-Like Receptor 4 Contributes to Host Immunity against Rickettsial Infection
Rumfield, C., Hyseni, I., McBride, J. W., Walker, D. H. & Fang, R., Mar 23 2020, In: Infection and immunity. 88, 4Research output: Contribution to journal › Article › peer-review
1 Scopus citations -
A single mutation (V64G) within the ring domain of Z attenuates junin virus
Hallam, S. J., Manning, J. T., Maruyama, J., Seregin, A., Huang, C., Walker, D. H., de la Torre, J. C. & Paessler, S., Sep 2020, In: PLoS neglected tropical diseases. 14, 9, p. 1-15 15 p., e0008555.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations -
Ehrlichia chaffeensis and E. canis hypothetical protein immunoanalysis reveals small secreted immunodominant proteins and conformation-dependent antibody epitopes
Luo, T., Patel, J. G., Zhang, X., Walker, D. H. & McBride, J. W., Dec 1 2020, In: npj Vaccines. 5, 1, 85.Research output: Contribution to journal › Article › peer-review
Open Access -
Human monocytic ehrlichiosis, Mexico City, Mexico
Alcántara-Rodríguez, V. E., Sánchez-Montes, S., Contreras, H., Colunga-Salas, P., Fierro-Flores, L., Avalos, S., Rodríguez-Rangel, F., Becker, I. & Walker, D. H., Dec 2020, In: Emerging infectious diseases. 26, 12, p. 3016-3019 4 p.Research output: Contribution to journal › Article › peer-review
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Human rickettsiosis caused by rickettsia parkeri strain Atlantic rainforest, Urabá, Colombia
Arboleda, M., Acevedo-Gutiérrez, L. Y., Ávila, A., Ospina, D., Díaz, F. J., Walker, D. H. & Rodas, J. D., Dec 2020, In: Emerging infectious diseases. 26, 12, p. 3048-3050 3 p.Research output: Contribution to journal › Article › peer-review
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Perspective Piece: Ideal Criteria for Accurate Mouse Models of Vector-Borne Diseases with Emphasis on Scrub Typhus and Dengue
Sarathy, V. V. & Walker, D. H., Sep 2020, In: American Journal of Tropical Medicine and Hygiene. 103, 3, p. 970-975 6 p.Research output: Contribution to journal › Review article › peer-review
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Quantitative Proteomics of the Endothelial Secretome Identifies RC0497 as Diagnostic of Acute Rickettsial Spotted Fever Infections
Zhao, Y., Fang, R., Zhang, J., Zhang, Y., Bechelli, J., Smalley, C., Valbuena, G., Walker, D. H., Oteo, J. A. & Brasier, A. R., Feb 2020, In: American Journal of Pathology. 190, 2, p. 306-322 17 p.Research output: Contribution to journal › Article › peer-review
Open Access3 Scopus citations -
Recent research milestones in the pathogenesis of human rickettsioses and opportunities ahead
Narra, H. P., Sahni, A., Walker, D. H. & Sahni, S. K., Jun 2020, In: Future Microbiology. 15, 9, p. 753-765 13 p.Research output: Contribution to journal › Review article › peer-review
1 Scopus citations -
The guinea pig model for tick-borne spotted fever rickettsioses: A second look
Stokes, J. V., Walker, D. H. & Varela-Stokes, A. S., Nov 2020, In: Ticks and Tick-borne Diseases. 11, 6, 101538.Research output: Contribution to journal › Review article › peer-review
Open Access -
2017
A review of the global epidemiology of scrub typhus
Xu, G., Walker, D. H., Jupiter, D., Melby, P. C. & Arcari, C. M., Nov 3 2017, In: PLoS neglected tropical diseases. 11, 11, e0006062.Research output: Contribution to journal › Article › peer-review
75 Scopus citations -
CD8+T cells provide immune protection against murine disseminated endotheliotropic Orientia tsutsugamushi infection
Xu, G., Mendell, N. L., Liang, Y., Shelite, T. R., Goez-Rivillas, Y., Soong, L., Bouyer, D. H. & Walker, D. H., Jul 19 2017, In: PLoS neglected tropical diseases. 11, 7, e0005763.Research output: Contribution to journal › Article › peer-review
15 Scopus citations -
Fibroblast growth factor receptor-1 mediates internalization of pathogenic spotted fever rickettsiae into host endothelium
Sahni, A., Patel, J., Narra, H. P., Schroeder, C. L. C., Walker, D. H. & Sahni, S. K., Aug 2017, In: PloS one. 12, 8, e0183181.Research output: Contribution to journal › Article › peer-review
10 Scopus citations -
Flea-Borne Rickettsioses and Rickettsiae
Blanton, L. S. & Walker, D. H., Jan 2017, In: American Journal of Tropical Medicine and Hygiene. 96, 1, p. 53-56 4 p.Research output: Contribution to journal › Review article › peer-review
34 Scopus citations -
Genotypic characterization of Orientia tsutsugamushi from patients in two geographical locations in Sri Lanka
Premaratna, R., Blanton, L. S., Samaraweera, D. N., de Silva, G. N. N., Chandrasena, N. T. G. A., Walker, D. H. & de Silva, H. J., Jan 13 2017, In: BMC Infectious Diseases. 17, 1, 67.Research output: Contribution to journal › Article › peer-review
9 Scopus citations -
Mechanisms of immunity to rickettsia and implications for vaccine development
Walker, D., Jan 1 2017, In: Revista Colombiana de Ciencias Pecuarias. 30, p. 262-263 2 p.Research output: Contribution to journal › Article › peer-review
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Murine models of scrub typhus associated with host control of Orientia tsutsugamushi infection
Mendell, N. L., Bouyer, D. H. & Walker, D. H., Mar 10 2017, In: PLoS neglected tropical diseases. 11, 3, e0005453.Research output: Contribution to journal › Article › peer-review
11 Scopus citations -
Rickettsiae as Emerging Infectious Agents
Fang, R., Blanton, L. S. & Walker, D. H., Jun 2017, In: Clinics in Laboratory Medicine. 37, 2, p. 383-400 18 p.Research output: Contribution to journal › Review article › peer-review
27 Scopus citations -
Time to Worry about Anthrax Again
Keim, P. S., Walker, D. H. & Zilinskas, R. A., Mar 14 2017, In: Scientific American. 316, 4, p. 70-75 6 p.Research output: Contribution to journal › Article › peer-review
1 Scopus citations -
2016
An Intradermal Inoculation Mouse Model for Immunological Investigations of Acute Scrub Typhus and Persistent Infection
Soong, L., Mendell, N. L., Olano, J. P., Rockx-Brouwer, D., Xu, G., Goez-Rivillas, Y., Drom, C., Shelite, T. R., Valbuena, G., Walker, D. H. & Bouyer, D. H., Aug 1 2016, In: PLoS neglected tropical diseases. 10, 8, e0004884.Research output: Contribution to journal › Article › peer-review
15 Scopus citations -
Editorial: Changing dynamics of human-rickettsial interactions
Walker, D. H., Jan 2016, In: American Journal of Tropical Medicine and Hygiene. 94, 1, p. 3-4 2 p.Research output: Contribution to journal › Editorial › peer-review
6 Scopus citations -
Ehrlichioses: An important one health opportunity
Saito, T. B. & Walker, D. H., Sep 1 2016, In: Veterinary Sciences. 3, 3, 20.Research output: Contribution to journal › Review article › peer-review
11 Scopus citations -
Endothelial Activation and Injury: The Mechanisms of Rickettsial Vasculiti
Sahni, A., Narra, H. P., Walker, D. H. & Sahni, S. K., 2016, Vascular Responses to Pathogens. Elsevier Inc., p. 111-122 12 p.Research output: Chapter in Book/Report/Conference proceeding › Chapter
5 Scopus citations -
Endothelial cell proteomic response to Rickettsia conorii infection reveals activation of the Janus Kinase (JAK)-signal transducer and activator of transcription (STAT)-inferferon stimulated gene (ISG)15 pathway and reprogramming plasma membrane integrin/cadherin signaling
Zhao, Y., Valbuena, G., Walker, D. H., Gazi, M., Hidalgo, M., DeSousa, R., Oteo, J. A., Goez, Y. & Brasier, A. R., Jan 2016, In: Molecular and Cellular Proteomics. 15, 1, p. 289-304 16 p.Research output: Contribution to journal › Article › peer-review
10 Scopus citations -
Epidemiology, molecular biology, and pathogenic mechanisms of Ehrlichia infections
Yu, X. J. & Walker, D., Jan 1 2016, Rickettsiales: Biology, Molecular Biology, Epidemiology, and Vaccine Development. Springer International Publishing, p. 225-240 16 p.Research output: Chapter in Book/Report/Conference proceeding › Chapter
1 Scopus citations -
Fatal monocytic ehrlichiosis in woman, Mexico, 2013
Sosa-Gutierrez, C. G., Solorzano-Santos, F., Walker, D. H., Torres, J., Serrano, C. A. & Gordillo-Perez, G., May 2016, In: Emerging infectious diseases. 22, 5, p. 871-874 4 p.Research output: Contribution to journal › Article › peer-review
8 Scopus citations -
MyD88 mediates instructive signaling in dendritic cells and protective inflammatory response during rickettsial infection
Bechelli, J., Smalley, C., Zhao, X., Judy, B., Valdes, P., Walker, D. H. & Fang, R., Apr 1 2016, In: Infection and immunity. 84, 4, p. 883-893 11 p.Research output: Contribution to journal › Article › peer-review
12 Scopus citations -
Opossums and cat fleas: New insights in the ecology of murine typhus in Galveston, Texas
Blanton, L. S., Idowu, B. M., Tatsch, T. N., Henderson, J. M., Bouyer, D. H. & Walker, D. H., Aug 2016, In: American Journal of Tropical Medicine and Hygiene. 95, 2, p. 457-461 5 p.Research output: Contribution to journal › Article › peer-review
32 Scopus citations -
Rickettsia
Walker, D., Oct 6 2016, International Encyclopedia of Public Health. Elsevier Inc., p. 370-377 8 p.Research output: Chapter in Book/Report/Conference proceeding › Chapter
2 Scopus citations -
Rickettsia australis activates inflammasome in human and murine macrophages
Smalley, C., Bechelli, J., Rockx-Brouwer, D., Saito, T., Azar, S. R., Ismail, N., Walker, D. H. & Fang, R., Jun 2016, In: PloS one. 11, 6, e0157231.Research output: Contribution to journal › Article › peer-review
14 Scopus citations -
Scrub typhus - Scientific neglect, ever-widening impact
Walker, D. H., Sep 8 2016, In: New England Journal of Medicine. 375, 10, p. 913-915 3 p.Research output: Contribution to journal › Short survey › peer-review
34 Scopus citations -
2013
Approaches to vaccines against Orientia tsutsugamushi
Valbuena, G. & Walker, D. H., 2013, In: Frontiers in Cellular and Infection Microbiology. 4, JAN, Article 170.Research output: Contribution to journal › Review article › peer-review
Open Access45 Scopus citations -
Approaches to vaccines against Orientia tsutsugamushi
Valbuena, G. & Walker, D. H., 2013, In: Frontiers in cellular and infection microbiology. 4, JAN, Article 170.Research output: Contribution to journal › Article › peer-review
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Case-Fatality ratio and effectiveness of ribavirin therapy among hospitalized patients in china who had severe fever with thrombocytopenia syndrome
Liu, W., Lu, Q. B., Cui, N., Li, H., Wang, L. Y., Liu, K., Yang, Z. D., Wang, B. J., Wang, H. Y., Zhang, Y. Y., Zhuang, L., Hu, C. Y., Yuan, C., Fan, X. J., Wang, Z., Zhang, L., Zhang, X. A., Walker, D. H. & Cao, W. C., Nov 1 2013, In: Clinical Infectious Diseases. 57, 9, p. 1292-1299 8 p.Research output: Contribution to journal › Article › peer-review
100 Scopus citations -
Compartmentalized, functional role of angiogenin during spotted fever group rickettsia-induced endothelial barrier dysfunction: Evidence of possible mediation by host tRNA-derived small noncoding RNAs
Gong, B., Lee, Y. S., Lee, I., Shelite, T. R., Kunkeaw, N., Xu, G., Lee, K., Jeon, S. H., Johnson, B. H., Chang, Q., Ha, T., Mendell, N. L., Cheng, X., Bouyer, D. H., Boor, P. J., Ksiazek, T. G. & Walker, D. H., Jun 23 2013, In: BMC Infectious Diseases. 13, 1, 285.Research output: Contribution to journal › Article › peer-review
27 Scopus citations -
Exchange protein directly activated by cAMP plays a critical role in bacterial invasion during fatal rickettsioses
Gong, B., Shelite, T., Mei, F. C., Ha, T., Hu, Y., Xu, G., Chang, Q., Wakamiya, M., Ksiazek, T. G., Boor, P. J., Bouyer, D. H., Popov, V. L., Chen, J., Walker, D. H. & Cheng, X., Nov 26 2013, In: Proceedings of the National Academy of Sciences of the United States of America. 110, 48, p. 19615-19620 6 p.Research output: Contribution to journal › Article › peer-review
49 Scopus citations -
Mice lacking functional STAT1 are highly susceptible to lethal infection with Lassa virus
Yun, N. E., Seregin, A. V., Walker, D. H., Popov, V. L., Walker, A. G., Smith, J. N., Miller, M., de la Torre, J. C., Smith, J. K., Borisevich, V., Fair, J. N., Wauquier, N., Grant, D. S., Bockarie, B., Bente, D. & Paessler, S., 2013, In: Journal of virology. 87, 19, p. 10908-10911 4 p.Research output: Contribution to journal › Article › peer-review
34 Scopus citations -
Pathogenesis of the viral hemorrhagic fevers
Paessler, S. & Walker, D. H., Jan 2013, In: Annual Review of Pathology: Mechanisms of Disease. 8, p. 411-440 30 p.Research output: Contribution to journal › Review article › peer-review
160 Scopus citations -
Recent molecular insights into rickettsial pathogenesis and immunity
Sahni, S. K., Narra, H. P., Sahni, A. & Walker, D. H., Oct 2013, In: Future Microbiology. 8, 10, p. 1265-1288 24 p.Research output: Contribution to journal › Review article › peer-review
59 Scopus citations -
Recombinant Ehrlichia P29 protein induces a protective immune response in a mouse model of ehrlichiosis
Thirumalapura, N. R., Crocquet-Valdes, P. A., Saito, T. B., Thomas, S., McBride, J. W. & Walker, D. H., Dec 5 2013, In: Vaccine. 31, 50, p. 5960-5967 8 p.Research output: Contribution to journal › Article › peer-review
4 Scopus citations -
Review article: Unresolved problems related to scrub typhus: A seriously neglected life-threatening disease
Paris, D. H., Shelite, T. R., Day, N. P. & Walker, D. H., Aug 2013, In: American Journal of Tropical Medicine and Hygiene. 89, 2, p. 301-307 7 p.Research output: Contribution to journal › Review article › peer-review
137 Scopus citations -
Rocky mountain spotted fever and other rickettsioses
Walker, D., Jul 8 2013, Schaechter's Mechanisms of Microbial Disease: Fifth Edition. Wolters Kluwer Health Adis (ESP), p. 301-307 7 p.Research output: Chapter in Book/Report/Conference proceeding › Chapter
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Simple method to differentiate among Rickettsia species
Peniche-Lara, G., Zavala-Velazquez, J., Dzul-Rosado, K., Walker, D. H. & Zavala-Castro, J., Apr 2013, In: Journal of Molecular Microbiology and Biotechnology. 23, 3, p. 203-208 6 p.Research output: Contribution to journal › Article › peer-review
8 Scopus citations -
Spotted fever group Rickettsia in small rodents from areas of low endemicity for Brazilian spotted fever in the Eastern Region of Minas Gerais State, Brazil
Milagres, B. S., Padilha, A. F., Montandon, C. E., Freitas, R. N., Pacheco, R., Walker, D. H., Labruna, M. B., Mafra, C. L. & Galvão, M. A. M., May 2013, In: American Journal of Tropical Medicine and Hygiene. 88, 5, p. 937-939 3 p.Research output: Contribution to journal › Article › peer-review
7 Scopus citations -
2011
Anthrax
Rao, G. R. & Walker, D. H., Dec 1 2011, Tropical Infectious Diseases. Elsevier Inc., p. 261-264 4 p.Research output: Chapter in Book/Report/Conference proceeding › Chapter
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Bartonelloses
Dehio, C., Maguiña, C. & Walker, D. H., Dec 1 2011, Tropical Infectious Diseases. Elsevier Inc., p. 265-270 6 p.Research output: Chapter in Book/Report/Conference proceeding › Chapter
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Diagnosing emerging and reemerging infectious diseases: The pivotal role of the pathologist
Olano, J. P. & Walker, D. H., Jan 1 2011, In: Archives of Pathology and Laboratory Medicine. 135, 1, p. 83-91 9 p.Research output: Contribution to journal › Article › peer-review
15 Scopus citations -
Distinguishing Tropical Infectious Diseases from Bioterrorism
Olano, J. P., Peters, C. J. & Walker, D. H., 2011, Tropical Infectious Diseases. Elsevier Inc., p. 879-886 8 p.Research output: Chapter in Book/Report/Conference proceeding › Chapter
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Fatal rocky mountain spotted fever in a 2-year-old child
Walker, D. H. & Paddock, C. D., Nov 1 2011, In: Pathology Case Reviews. 16, 6, p. 238-241 4 p.Research output: Contribution to journal › Review article › peer-review
1 Scopus citations -
Fever with thrombocytopenia associated with a novel bunyavirus in China
Yu, X. J., Liang, M. F., Zhang, S. Y., Liu, Y., Li, J. D., Sun, Y. L., Zhang, L., Zhang, Q. F., Popov, V. L., Li, C., Qu, J., Li, Q., Zhang, Y. P., Hai, R., Wu, W., Wang, Q., Zhan, F. X., Wang, X. J., Kan, B., Wang, S. W. & 26 others, , Apr 21 2011, In: New England Journal of Medicine. 364, 16, p. 1523-1532 10 p.Research output: Contribution to journal › Article › peer-review
767 Scopus citations -
Immunization with Ehrlichia P28 outer membrane proteins confers protection in a mouse model of ehrlichiosis
Crocquet-Valdes, P. A., Thirumalapura, N. R., Ismail, N., Yu, X., Saito, T. B., Stevenson, H. L., Pietzsch, C. A., Thomas, S. & Walker, D. H., Dec 2011, In: Clinical and Vaccine Immunology. 18, 12, p. 2018-2025 8 p.Research output: Contribution to journal › Article › peer-review
17 Scopus citations