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• 2020

  HSD3B1 genotype identifies glucocorticoid responsiveness in severe asthma

  Zein, J., Gaston, B., Bazeley, P., DeBoer, M. D., Igo, R. P., Bleecker, E. R., Meyers, D., Comhair, S., Marozkina, N. V., Cotton, C., Patel, M., Alyamani, M., Xu, W., Busse, W. W., Calhoun, W. J., Ortega, V., Hawkins, G. A., Castro, M., Chung, K. F., Fahy, J. V. & 12 others, Fitzpatrick, A. M., Israel, E., Jarjour, N. N., Levy, B., Mauger, D. T., Moore, W. C., Noel, P., Peters, S. P., Teague, W. G., Wenzel, S. E., Erzurum, S. C. & Sharifi, N., Jan 28 2020, In: Proceedings of the National Academy of Sciences of the United States of America. 117, 4, p. 2187-2193 7 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Glucocorticoids
  • Asthma
  • Genotype
  • Androgens
  • 3-Hydroxysteroid Dehydrogenases
  3 Scopus citations

• Management of Acute Asthma in Adults in 2020

  Zaidan, M. F., Ameredes, B. T. & Calhoun, W. J., Feb 11 2020, In: JAMA - Journal of the American Medical Association. 323, 6, p. 563-564 2 p.

  Research output: Contribution to journal › Short survey › peer-review
  1 Scopus citations

• Outpatient Management of Chronic Asthma in 2020

  Tripple, J. W., Ameredes, B. T. & Calhoun, W. J., Feb 11 2020, In: JAMA - Journal of the American Medical Association. 323, 6, p. 561-562 2 p.

  Research output: Contribution to journal › Short survey › peer-review
  3 Scopus citations
• 2017

  Activation of Human Peripheral Blood Eosinophils by Cytokines in a Comparative Time-Course Proteomic/Phosphoproteomic Study

  Soman, K. V., Stafford, S. J., Pazdrak, K., Wu, Z., Luo, X., White, W. I., Wiktorowicz, J. E., Calhoun, W. J. & Kurosky, A., Aug 4 2017, In: Journal of Proteome Research. 16, 8, p. 2663-2679 17 p.

  Research output: Contribution to journal › Article › peer-review

  • Proteomics
  • Eosinophils
  • Blood
  • Chemical activation
  • Cytokines
  8 Scopus citations

• Biologic Therapy in Chronic Obstructive Pulmonary Disease

  Tripple, J., McCracken, J. & Calhoun, W., May 1 2017, In: Immunology and Allergy Clinics of North America. 37, 2, p. 345-355 11 p.

  Research output: Contribution to journal › Review article › peer-review

  • Biological Therapy
  • Chronic Obstructive Pulmonary Disease
  • Inflammation
  • Environmental Exposure
  • Biological Factors
  5 Scopus citations

• Diagnosis and management of asthma in adults a review

  McCracken, J., Veeranki, S. P., Ameredes, B. & Calhoun, W., Jul 18 2017, In: JAMA - Journal of the American Medical Association. 318, 3, p. 279-290 12 p.

  Research output: Contribution to journal › Review article › peer-review

  • Asthma
  • Adrenal Cortex Hormones
  • Biological Factors
  • Airway Obstruction
  • reslizumab
  66 Scopus citations

• Identification of airway mucosal type 2 inflammation by using clinical biomarkers in asthmatic patients

  Silkoff, P. E., Laviolette, M., Singh, D., FitzGerald, J. M., Kelsen, S., Backer, V., Porsbjerg, C. M., Girodet, P. O., Berger, P., Kline, J. N., Chupp, G., Susulic, V. S., Barnathan, E. S., Baribaud, F., Loza, M. J., Strambu, I., Lam, S., Eich, A., Ludwig-Sengpiel, A., Leigh, R. & 4 others, Dransfield, M., Calhoun, W., Hussaini, A. & Chanez, P., Sep 2017, In: Journal of Allergy and Clinical Immunology. 140, 3, p. 710-719 10 p.

  Research output: Contribution to journal › Article › peer-review

  • Asthma
  • Eosinophils
  • Biomarkers
  • Nitric Oxide
  • Inflammation
  27 Scopus citations

• Post-transplant native pneumonectomy for interstitial fibrosis and small cell lung cancer

  Li, R. T., Zahedi, S., Trieu, J., Lea, A. S., Calhoun, W. J., Duarte, A. G., Zhao, J. & Okereke, I. C., Dec 1 2017, In: Journal of Thoracic Disease. 9, 12, p. E1096-E1099

  Research output: Contribution to journal › Article › peer-review

  • Pneumonectomy
  • Lung Transplantation
  • Small Cell Lung Carcinoma
  • Lung Neoplasms
  • Fibrosis

• Race is associated with differences in airway inflammation in patients with asthma

  Nyenhuis, S. M., Krishnan, J. A., Berry, A., Calhoun, W. J., Chinchilli, V. M., Engle, L., Grossman, N., Holguin, F., Israel, E., Kittles, R. A., Kraft, M., Lazarus, S. C., Lehman, E. B., Mauger, D. T., Moy, J. N., Peters, S. P., Phipatanakul, W., Smith, L. J., Sumino, K., Szefler, S. J. & 4 others, Wechsler, M. E., Wenzel, S., White, S. R. & Ackerman, S. J., Jul 2017, In: Journal of Allergy and Clinical Immunology. 140, 1, p. 257-265.e11

  Research output: Contribution to journal › Article › peer-review

  • African Americans
  • European Continental Ancestry Group
  • Asthma
  • Inflammation
  • Sputum
  19 Scopus citations
• 2016

  30-Day Readmissions in Hospitalized Adults With Asthma Exacerbations: Insights From the Nationwide Readmission Database

  Veeranki, S. P., Sharma, K., Ohabughiro, M. U., Mehta, H. B., Adhikari, D., Kuo, Y. F. & Calhoun, W. J., Nov 1 2016, In: Chest. 150, 5, p. 1162-1165 4 p.

  Research output: Contribution to journal › Letter › peer-review
  6 Scopus citations

• Biologic therapy in the management of asthma

  McCracken, J. L., Tripple, J. W. & Calhoun, W. J., Aug 1 2016, In: Current opinion in allergy and clinical immunology. 16, 4, p. 375-382 8 p.

  Research output: Contribution to journal › Review article › peer-review

  • Biological Therapy
  • Asthma
  • Biological Factors
  • Leukotrienes
  • Bronchodilator Agents
  27 Scopus citations

• Cytokine-induced glucocorticoid resistance from eosinophil activation: Protein phosphatase 5 modulation of glucocorticoid receptor phosphorylation and signaling

  Pazdrak, K., Straub, C., Maroto, R., Stafford, S., White, W. I., Calhoun, W. J. & Kurosky, A., Nov 15 2016, In: Journal of Immunology. 197, 10, p. 3782-3791 10 p.

  Research output: Contribution to journal › Article › peer-review

  • protein phosphatase 5
  • Glucocorticoid Receptors
  • Eosinophils
  • Phosphorylation
  • Cytokines
  20 Scopus citations

• Effects of acute ethanol exposure on cytokine production by primary airway smooth muscle cells

  Kaphalia, L., Kalita, M., Kaphalia, B. S. & Calhoun, W. J., Feb 1 2016, In: Toxicology and Applied Pharmacology. 292, p. 85-93 9 p.

  Research output: Contribution to journal › Article › peer-review

  • Acetaldehyde
  • Pulmonary diseases
  • Esters
  • Cells
  • Muscle
  7 Scopus citations

• Impact of Age and Sex on Outcomes and Hospital Cost of Acute Asthma in the United States, 2011-2012

  Zein, J. G., Udeh, B. L., Teague, W. G., Koroukian, S. M., Schlitz, N. K., Bleecker, E. R., Busse, W. B., Calhoun, W. J., Castro, M., Comhair, S. A., Fitzpatrick, A. M., Israel, E., Wenzel, S. E., Holguin, F., Gaston, B. M. & Erzurum, S. C., Jun 2016, In: PloS one. 11, 6, e0157301.

  Research output: Contribution to journal › Article › peer-review

  • Hospital Costs
  • asthma
  • Asthma
  • gender
  • Costs
  30 Scopus citations

• Improving Quality of Acute Asthma Care in US Hospitals: Changes Between 1999-2000 and 2012-2013

  Hasegawa, K., Tsugawa, Y., Clark, S., Eastin, C. D., Gabriel, S., Herrera, V., Bittner, J. C., Camargo, C. A., Ahn, J., Aurora, T., Brenner, B., Brown, M. A., Calhoun, W., Gough, J. E., Gharib, A., Heidt, J., Khosravi, M., Moore, W. C., Mould-Millman, N. K., Nonas, S. & 11 others, Nowak, R., Pei, V., Press, V. G., Probst, B. D., Ramratnam, S. K., Tallar, M., Teuber, S. S., Trent, S. A., Villarreal, R., Watase, T. & Youngquist, S., Jul 1 2016, In: Chest. 150, 1, p. 112-122 11 p.

  Research output: Contribution to journal › Article › peer-review

  • Asthma
  • Guidelines
  • Length of Stay
  • Inpatients
  • Hospitalized Child
  10 Scopus citations

• Longitudinal stability of asthma characteristics and biomarkers from the Airways Disease Endotyping for Personalized Therapeutics (ADEPT) study

  The ADEPT Investigators, 2016, In: Respiratory Research. 17, 1, p. 1-12 12 p., 43.

  Research output: Contribution to journal › Article › peer-review

  • Asthma
  • Biomarkers
  • Nitric Oxide
  • Phenotype
  • Bronchodilator Agents
  18 Scopus citations

• Validated and longitudinally stable asthma phenotypes based on cluster analysis of the ADEPT study

  For the ADEPT (Airways Disease Endotyping for Personalized Therapeutics) & U-BIOPRED (Unbiased Biomarkers for the Prediction of Respiratory Disease Outcome Consortium) investigators, Dec 15 2016, In: Respiratory Research. 17, 1, 165.

  Research output: Contribution to journal › Article › peer-review

  • Cluster Analysis
  • Asthma
  • Phenotype
  • Inflammation
  • Interleukin-13
  47 Scopus citations
• 2015

  Anticholinergic vs long-acting β-Agonist in combination with inhaled corticosteroids in black adults with asthma: The BELT randomized clinical trial

  Wechsler, M. E., Yawn, B. P., Fuhlbrigge, A. L., Pace, W. D., Pencina, M. J., Doros, G., Kazani, S., Raby, B. A., Lanzillotti, J., Madison, S., Israel, E., Ansari, A., Raum, D., Marthur, M., Avila, P., Bailey, J. E., Calhoun, W. J., Chang, K. L., Coto, M., Davis, C. & 8 others, Dawson, R., Ferguson, M. L. F., Dransfield, M. T., Ferguson, F., Greiner, A., Jingo, A., Pankey, W. & Schear, M., Oct 27 2015, In: JAMA - Journal of the American Medical Association. 314, 16, p. 1720-1730 11 p.

  Research output: Contribution to journal › Article › peer-review

  • Cholinergic Antagonists
  • African Continental Ancestry Group
  • Tiotropium Bromide
  • Adrenal Cortex Hormones
  • Asthma
  40 Scopus citations

• Asthma characteristics and biomarkers from the Airways Disease Endotyping for Personalized Therapeutics (ADEPT) longitudinal profiling study

  Silkoff, P. E., Strambu, I., Laviolette, M., Singh, D., FitzGerald, J. M., Lam, S., Kelsen, S., Eich, A., Ludwig-Sengpiel, A., hupp, G. C., Backer, V., Porsbjerg, C., Girodet, P. O., Berger, P., Leigh, R., Kline, J. N., Dransfield, M., Calhoun, W., Hussaini, A., Khatri, S. & 8 others, Chanez, P., Susulic, V. S., Barnathan, E. S., Curran, M., Das, A. M., Brodmerkel, C., Baribaud, F. & Loza, M. J., Nov 17 2015, In: Respiratory Research. 16, 1, 142.

  Research output: Contribution to journal › Article › peer-review

  • Longitudinal Studies
  • Asthma
  • Biomarkers
  • Sputum
  • Bronchoscopy
  34 Scopus citations

• Asthma exacerbations and lung function in patients with severe or difficult-to-treat asthma

  Calhoun, W., Haselkorn, T., Miller, D. P. & Omachi, T. A., Oct 1 2015, In: Journal of Allergy and Clinical Immunology. 136, 4, p. 1125-1127e4

  Research output: Contribution to journal › Article › peer-review
  20 Scopus citations

• Asthma is more severe in older adults

  Zein, J. G., Dweik, R. A., Comhair, S. A., Bleecker, E. R., Moore, W. C., Peters, S. P., Busse, W. W., Jarjour, N. N., Calhoun, W. J., Castro, M., Chung, K. F., Fitzpatrick, A., Israel, E., Teague, W. G., Wenzel, S. E., Love, T. E., Gaston, B. M. & Erzurum, S. C., Jul 22 2015, In: PloS one. 10, 7, e0133490.

  Research output: Contribution to journal › Article › peer-review

  • asthma
  • Asthma
  • Aging of materials
  • duration
  • Logistics
  43 Scopus citations

• Children and Adults With Frequent Hospitalizations for Asthma Exacerbation, 2012-2013: A Multicenter Observational Study

  Multicenter Airway Research Collaboration-37 Investigators, Sep 1 2015, In: Journal of Allergy and Clinical Immunology: In Practice. 3, 5, p. 751-758.e1

  Research output: Contribution to journal › Article › peer-review

  • Multicenter Studies
  • Observational Studies
  • Asthma
  • Hospitalization
  • Child
  25 Scopus citations

• Clinical implications of having reduced mid forced expiratory flow rates (FEF_25-75), independently of FEV1, in adult patients with asthma

  Riley, C. M., Wenzel, S. E., Castro, M., Erzurum, S. C., Chung, K. F., Fitzpatrick, A. M., Gaston, B., Israel, E., Moore, W. C., Bleecker, E. R., Calhoun, W. J., Jarjour, N. N., Busse, W. W., Peters, S. P., Teague, W. G., Sorkness, R. & Holguin, F., Dec 2015, In: PloS one. 10, 12, e0145476.

  Research output: Contribution to journal › Article › peer-review

  • Forced Expiratory Flow Rates
  • Intensive care units
  • Biomarkers
  • asthma
  • Eosinophils
  18 Scopus citations

• Effect of a soy isoflavone supplement on lung function and clinical outcomes in patients with poorly controlled asthma: A randomized clinical trial

  Smith, L. J., Kalhan, R., Wise, R. A., Sugar, E. A., Lima, J. J., Irvin, C. G., Dozor, A. J., Holbrook, J. T., Hanania, N., Sockrider, M., Bertrand, L., Atik, M. A., Lopez, B. A., Reibman, J., DiMango, E., Rogers, L., Carapetyan, K., Rivera, K., Bryce-Robinson, N., Scheuerman, M. & 180 others, Fiorino, E., Sundy, J., Green, D., Shah, A., Foss, C., Ghidorzi, J., Allen, S., Mervin-Blake, S., Pangborn, E., Robertson, V. S., Eberlein, N., Land, M., Vickery, B., Wu, E., Jaggers, D., Moy, J., Naureckas, E., Nevin, M., Hixon, J., Brees, A., Gonsalves, Z., Zagaja, V., Kustwin, J., Xu, B., Matthews, T., Robinson, L., Singh, N., Busk, M., Puntenney, P., Busk, N., Hutchins, J., Happel, K. I., Tejedor, R. S., Sandi, M. C., Romaine, C., Burzynski, C. J., Antoine, A., Cruse, J., Katial, R., Hoyte, F., Searing, D., Larson, T., Phillips, N., Currier, H., Blake, K., Lang, J., Mougey, E., Archer, N., Seymour, D., Warde, M., Cohen, R., Santiago, M., Ramdeo, R., Dreyfus, M., Dixon, A. E., Kaminsky, D. A., Lahiri, T., Burns, S. M., Mastronarde, J., Parsons, J., Drake, J., Santiago, J., Cosmar, D., Compton, R. A., Krishnan, S., Boyer, J., Banquet, A., De La Riva-Velasco, E., Lowenthal, D., Gjonaj, S., Kim, Y. C., Traeger, N., Welter, J., Scharbach, M., Siegel, S., Gherson, I., Monchil, L., Formisano, T. M., Williams, J., Castro, M., Bacharier, L., Sumino, K., Tarsi, J. J., Patterson, B., Montgomery, T., Slavin, R. G., Chassaing, D. K., Gerald, L. B., Goodwin, J. L., Brown, M. A., Knox, K. S., Carr, T. F., Berry, C. E., Martinez, F. D., Morgan, W. J., Daines, C. L., Daines, M. O., Grad, R., Ezmigna, D., Vasquez, M. M., Wences, J. A., Lopez, S. S., Priefert, J. C., Varela, M. T., Weese, R., Chee, K., Paco, A., Wanner, A., Lockey, R., Schmid, A., Campos, M., King, M., Mendes, E. S., Rebolledo, P. D., Arana, J., Cadet, L., McCrery, R., Croker, S. M., McCullough, S., Salzman, G., Abdeljalil, A., Pyszczynski, D., Bhat, A., Haney, P., Wasserman, S., Ramsdell, J., Soler, X., Kinninger, K., Ferguson, P., Martineau, A., Ung, S., Greene, T., Teague, W. G., Wavell, K. W., Wolf, D., Thompson-Batt, D., Bailey, W. C., Anthonisen, N., Yasin, R., Amend-Libercci, D., Adler, A., Casper, A. S., Daniel, M., Hart, A., Lears, A., Leatherman, G., Nowakowski, D., Prusakowski, N., Rayapudi, S., Rea, A., Saams, J., Shade, D., Thurman, A., Wei, C., Newcomer, A., Bime, C., Brown, E., Levine, C., Roettger, S., Wu, N., Shen, W., Wang, L., Ukken, J., Lazarus, S. C., Calhoun, W. J., Cloutier, M., Kahrilas, P., McWilliams, B., Rogatko, A., Sorkness, C., Sicherer, S., Weinmann, G., Freemer, M., Smith, R., Taggart, V., Webber, L., Zheng, G., Lancet, E., Edelman, N. H. & Rappaport, S., May 26 2015, In: JAMA - Journal of the American Medical Association. 313, 20, p. 2033-2043 11 p.

  Research output: Contribution to journal › Article › peer-review

  • Isoflavones
  • Asthma
  • Randomized Controlled Trials
  • Lung
  • Placebos
  20 Scopus citations

• Evolution of Multidisciplinary Translational Teams (MTTs): Insights for Accelerating Translational Innovations

  Wooten, K. C., Calhoun, W. J., Bhavnani, S., Rose, R. M., Ameredes, B. & Brasier, A. R., Oct 2015, In: Clinical and translational science. 8, 5, p. 542-552 11 p.

  Research output: Contribution to journal › Article › peer-review

  • Process Assessment (Health Care)
  • Productivity
  • Outcome Assessment (Health Care)
  • Consensus
  • Bibliometrics
  8 Scopus citations

• Sex differences in hospital length of stay in children and adults hospitalized for asthma exacerbation

  Hasegawa, K., Calhoun, W. J., Pei, Y. V., Chasm, R. M., Youngquist, S. T., Bittner, J. C. & Camargo, C. A., Dec 1 2015, In: Annals of Allergy, Asthma and Immunology. 115, 6, p. 533-535.e1

  Research output: Contribution to journal › Article › peer-review
  4 Scopus citations

• Therapeutic potential of anti-IL-6 therapies for granulocytic airway inflammation in asthma

  Chu, D. K., Al-Garawi, A., Llop-Guevara, A., Pillai, R. A., Radford, K., Shen, P., Walker, T. D., Goncharova, S., Calhoun, W. J., Nair, P. & Jordana, M., Apr 12 2015, In: Allergy, Asthma and Clinical Immunology. 11, 1, 14.

  Research output: Contribution to journal › Article › peer-review

  • Interleukin-6
  • Asthma
  • Inflammation
  • Bronchitis
  • Chemokines
  38 Scopus citations

• The role of computed tomography in chronic obstructive pulmonary diseases

  Sze, T. F. C., Ditzler, M. G., Walser, E. M. & Calhoun, W. J., 2015, In: Journal of Allergy and Clinical Immunology: In Practice. 3, 4, p. 594-596 3 p.

  Research output: Contribution to journal › Article › peer-review
  1 Scopus citations

• Underuse of guideline-recommended long-term asthma management in children hospitalized to the intensive care unit: A multicenter observational study

  Hasegawa, K., Ahn, J., Brown, M. A., Press, V. G., Gabriel, S., Herrera, V., Bittner, J. C., Camargo, C. A., Aurora, T., Brenner, B., Calhoun, W., Gough, J. E., Gutta, R. C., Heidt, J., Khosravi, M., Moore, W. C., Mould-Millman, N. K., Nonas, S., Nowak, R., Pei, V. & 9 others, Probst, B. D., Ramratnam, S. K., Tallar, M., Snipes, C., Teuber, S. S., Trent, S. A., Villarreal, R., Watase, T. & Youngquist, S., Jul 1 2015, In: Annals of Allergy, Asthma and Immunology. 115, 1, p. 10-16.e1

  Research output: Contribution to journal › Article › peer-review

  • Hospitalized Child
  • Multicenter Studies
  • Intensive Care Units
  • Observational Studies
  • Asthma
  21 Scopus citations
• 2014

  Assessing and Evaluating Multidisciplinary Translational Teams: A Mixed Methods Approach

  Wooten, K. C., Rose, R. M., Ostir, G. V., Calhoun, W. J., Ameredes, B. T. & Brasier, A. R., 2014, In: Evaluation and the Health Professions. 37, 1, p. 33-49 17 p.

  Research output: Contribution to journal › Article › peer-review
  13 Scopus citations

• Clinical burden and predictors of asthma exacerbations in patients on guideline-based steps 4-6 asthma therapy in the TENOR cohort

  Calhoun, W. J., Haselkorn, T., Mink, D. R., Miller, D. P., Dorenbaum, A. & Zeiger, R. S., Mar 2014, In: Journal of Allergy and Clinical Immunology: In Practice. 2, 2, p. 193-200.e3

  Research output: Contribution to journal › Article › peer-review

  • Asthma
  • Guidelines
  • Odds Ratio
  • Quality of Life
  • Therapeutics
  30 Scopus citations

• Conclusions and future directions

  Calhoun, W. J. & Brasier, A. R., 2014, Advances in Experimental Medicine and Biology. Vol. 795. p. 335-343 9 p. (Advances in Experimental Medicine and Biology; vol. 795).

  Research output: Chapter in Book/Report/Conference proceeding › Chapter

• Conclusions and future directions

  Calhoun, W. & Brasier, A. R., 2014, Advances in Experimental Medicine and Biology. Springer New York LLC, Vol. 795. p. 335-343 9 p. (Advances in Experimental Medicine and Biology; vol. 795).

  Research output: Chapter in Book/Report/Conference proceeding › Chapter
  1 Scopus citations

• Ethanol metabolism, oxidative stress, and endoplasmic reticulum stress responses in the lungs of hepatic alcohol dehydrogenase deficient deer mice after chronic ethanol feeding

  Kaphalia, L., Boroumand, N., Hyunsu, J., Kaphalia, B. S. & Calhoun, W. J., Jun 1 2014, In: Toxicology and Applied Pharmacology. 277, 2, p. 109-117 9 p.

  Research output: Contribution to journal › Article › peer-review

  • Oxidative stress
  • Peromyscus
  • Alcohol Dehydrogenase
  • Metabolism
  • Endoplasmic Reticulum Stress
  18 Scopus citations

• Heterogeneity of asthma in society

  Divekar, R. & Calhoun, W. J., 2014, Advances in Experimental Medicine and Biology. Vol. 795. p. 31-41 11 p. (Advances in Experimental Medicine and Biology; vol. 795).

  Research output: Chapter in Book/Report/Conference proceeding › Chapter

  • Vitamin D
  • Asthma
  • Immunologic Factors
  • Animals
  • Obesity

• Heterogeneity of asthma in society

  Divekar, R. & Calhoun, W., 2014, Advances in Experimental Medicine and Biology. Springer New York LLC, Vol. 795. p. 31-41 11 p. (Advances in Experimental Medicine and Biology; vol. 795).

  Research output: Chapter in Book/Report/Conference proceeding › Chapter

  • Vitamin D
  • Asthma
  • Immunologic Factors
  • Animals
  • Obesity
  4 Scopus citations

• Heterogeneity of response to therapy

  Calhoun, W. J., 2014, Advances in Experimental Medicine and Biology. Vol. 795. p. 117-122 6 p. (Advances in Experimental Medicine and Biology; vol. 795).

  Research output: Chapter in Book/Report/Conference proceeding › Chapter

  • Asthma
  • Physiology
  • Restoration
  • Therapeutics
  • History

• Heterogeneity of response to therapy

  Calhoun, W., 2014, Advances in Experimental Medicine and Biology. Springer New York LLC, Vol. 795. p. 117-122 6 p. (Advances in Experimental Medicine and Biology; vol. 795).

  Research output: Chapter in Book/Report/Conference proceeding › Chapter

  • Asthma
  • Physiology
  • Restoration
  • Therapeutics
  • History

• Introduction to asthma and phenotyping

  Pillai, R. A. & Calhoun, W., 2014, Advances in Experimental Medicine and Biology. Springer New York LLC, Vol. 795. p. 5-15 11 p. (Advances in Experimental Medicine and Biology; vol. 795).

  Research output: Chapter in Book/Report/Conference proceeding › Chapter

  • Asthma
  • Phenotype
  • Airway Obstruction
  • Patient Care
  • Inflammation
  5 Scopus citations

• Introduction to asthma and phenotyping

  Pillai, R. A. & Calhoun, W. J., 2014, Advances in Experimental Medicine and Biology. Vol. 795. p. 5-15 11 p. (Advances in Experimental Medicine and Biology; vol. 795).

  Research output: Chapter in Book/Report/Conference proceeding › Chapter

  • Asthma
  • Phenotype
  • Airway Obstruction
  • Patient Care
  • Inflammation

• The spectrum of asthma: an introduction.

  Calhoun, W. J., 2014, In: Advances in experimental medicine and biology. 795, p. 1-4 4 p.

  Research output: Contribution to journal › Editorial › peer-review

• Unsupervised phenotyping of Severe Asthma Research Program participants using expanded lung data

  Wu, W., Bleecker, E., Moore, W., Busse, W. W., Castro, M., Chung, K. F., Calhoun, W. J., Erzurum, S., Gaston, B., Israel, E., Curran-Everett, D. & Wenzel, S. E., May 2014, In: Journal of Allergy and Clinical Immunology. 133, 5, p. 1280-1288 9 p.

  Research output: Contribution to journal › Article › peer-review

  • Asthma
  • Lung
  • Unsupervised Machine Learning
  • Cluster Analysis
  • Asthma and Nasal Polyps
  149 Scopus citations
• 2011

  Airway microbiota and bronchial hyperresponsiveness in patients with suboptimally controlled asthma

  Huang, Y. J., Nelson, C. E., Brodie, E. L., Desantis, T. Z., Baek, M. S., Liu, J., Woyke, T., Allgaier, M., Bristow, J., Wiener-Kronish, J. P., Sutherland, E. R., King, T. S., Icitovic, N., Martin, R. J., Calhoun, W. J., Castro, M., Denlinger, L. C., Dimango, E., Kraft, M., Peters, S. P. & 4 others, Wasserman, S. I., Wechsler, M. E., Boushey, H. A. & Lynch, S. V., Feb 2011, In: Journal of Allergy and Clinical Immunology. 127, 2, p. 372-381.e3

  Research output: Contribution to journal › Article › peer-review

  • Microbiota
  • Asthma
  • 16S Ribosomal RNA
  • Oxalobacteraceae
  • Sphingomonadaceae
  423 Scopus citations

• Can anti-IgE therapy prevent airway remodeling in allergic asthma?

  Rabe, K. F., Calhoun, W. J., Smith, N. & Jimenez, P., Sep 2011, In: Allergy: European Journal of Allergy and Clinical Immunology. 66, 9, p. 1142-1151 10 p.

  Research output: Contribution to journal › Review article › peer-review

  • Distance Counseling
  • Airway Remodeling
  • Passive Immunization
  • Immunoglobulin E
  • Asthma
  45 Scopus citations

• Current prospective of aldose reductase inhibition in the therapy of allergic airway inflammation in asthma

  Ramana, K. V., Yadav, U. C. S., Calhoun, W. J. & Srivastava, S. K., Jan 1 2011, In: Current molecular medicine. 11, 7, p. 599-608 10 p.

  Research output: Contribution to journal › Review article › peer-review

  • Aldehyde Reductase
  • Asthma
  • Inflammation
  • Steroids
  • polyol
  6 Scopus citations

• Determinants of exhaled breath condensate pH in a large population with asthma

  Liu, L., Teague, W. G., Erzurum, S., Fitzpatrick, A., Mantri, S., Dweik, R. A., Bleecker, E. R., Meyers, D., Busse, W. W., Calhoun, W. J., Castro, M., Chung, K. F., Curran-Everett, D., Israel, E., Jarjour, W. N., Moore, W., Peters, S. P., Wenzel, S., Hunt, J. F. & Gaston, B., Feb 1 2011, In: Chest. 139, 2, p. 328-336 9 p.

  Research output: Contribution to journal › Article › peer-review

  • Asthma
  • Population
  • Dimercaprol
  • Population Dynamics
  • Gastroesophageal Reflux
  53 Scopus citations

• Detrimental effects of environmental tobacco smoke in relation to asthma severity

  Comhair, S. A. A., Gaston, B. M., Ricci, K. S., Hammel, J., Dweik, R. A., Teague, W. G., Meyers, D., Ampleford, E. J., Bleecker, E. R., Busse, W. W., Calhoun, W. J., Castro, M., Chung, K. F., Curran-Everett, D., Israel, E., Jarjour, W. N., Moore, W., Peters, S. P., Wenzel, S., Hazen, S. L. & 1 others, Erzurum, S. C., 2011, In: PloS one. 6, 5, e18574.

  Research output: Contribution to journal › Article › peer-review

  • Tobacco
  • asthma
  • smoke
  • Smoke
  • tobacco
  81 Scopus citations

• How cytokines co-occur across asthma patients: From bipartite network analysis to a molecular-based classification

  Bhavnani, S. K., Victor, S., Calhoun, W. J., Busse, W. W., Bleecker, E., Castro, M., Ju, H., Pillai, R., Oezguen, N., Bellala, G. & Brasier, A. R., Dec 2011, In: Journal of Biomedical Informatics. 44, SUPPL. 1, p. S24-S30

  Research output: Contribution to journal › Article › peer-review

  • Cytokines
  • Electric network analysis
  • Asthma
  • Glucocorticoids
  • Visualization
  21 Scopus citations

• Impact of race on asthma treatment failures in the Asthma Clinical Research Network

  Wechsler, M. E., Castro, M., Lehman, E., Chinchilli, V. M., Sutherland, E. R., Denlinger, L., Lazarus, S. C., Peters, S. P., Israel, E., Martin, R. J., Szefler, S. J., Cherniack, R., Lemanske, R. F., Sorkness, C. A., Jarjour, N., Craig, T., Kunselman, S. J., Boushey, H. A., Fahy, J. V., Kraft, M. & 9 others, Wasserman, S., Ramsdell, J., Calhoun, W. J., Ameredes, B., Walter, M., Bleecker, E., DiMango, E., Pesola, G. R. & Smith, R., Dec 1 2011, In: American Journal of Respiratory and Critical Care Medicine. 184, 11, p. 1247-1253 7 p.

  Research output: Contribution to journal › Article › peer-review

  • Treatment Failure
  • Asthma
  • European Continental Ancestry Group
  • African Americans
  • Bronchial Hyperreactivity
  60 Scopus citations

• Importance of hedgehog interacting protein and other lung function genes in asthma

  Li, X., Howard, T. D., Moore, W. C., Ampleford, E. J., Li, H., Busse, W. W., Calhoun, W. J., Castro, M., Chung, K. F., Erzurum, S. C., Fitzpatrick, A. M., Gaston, B., Israel, E., Jarjour, N. N., Teague, W. G., Wenzel, S. E., Peters, S. P., Hawkins, G. A., Bleecker, E. R. & Meyers, D. A., Jun 2011, In: Journal of Allergy and Clinical Immunology. 127, 6, p. 1457-1465 9 p.

  Research output: Contribution to journal › Article › peer-review

  • Hedgehog Proteins
  • Asthma
  • Lung
  • Genes
  • Single Nucleotide Polymorphism
  92 Scopus citations