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2019
A tale of two states: Normal and transformed, with and without rigidity sensing
Sheetz, M., 2019, In: Annual Review of Cell and Developmental Biology. 35, p. 169-190 22 p.Research output: Contribution to journal › Review article › peer-review
4 Scopus citations -
Integrin Mechano-chemical Signaling Generates Plasma Membrane Nanodomains that Promote Cell Spreading
Kalappurakkal, J. M., Anilkumar, A. A., Patra, C., van Zanten, T. S., Sheetz, M. P. & Mayor, S., Jun 13 2019, In: Cell. 177, 7, p. 1738-1756.e23Research output: Contribution to journal › Article › peer-review
Open Access25 Scopus citations -
Integrin nanoclusters can bridge thin matrix fibres to form cell–matrix adhesions
Changede, R., Cai, H., Wind, S. J. & Sheetz, M. P., Dec 1 2019, In: Nature Materials. 18, 12, p. 1366-1375 10 p.Research output: Contribution to journal › Article › peer-review
23 Scopus citations -
Large and reversible myosin-dependent forces in rigidity sensing
Lohner, J., Rupprecht, J. F., Hu, J., Mandriota, N., Saxena, M., de Araujo, D. P., Hone, J., Sahin, O., Prost, J. & Sheetz, M., Jul 1 2019, In: Nature Physics. 15, 7, p. 689-695 7 p.Research output: Contribution to journal › Article › peer-review
10 Scopus citations -
Myosin IIA and formin dependent mechanosensitivity of filopodia adhesion
Alieva, N. O., Efremov, A. K., Hu, S., Oh, D., Chen, Z., Natarajan, M., Ong, H. T., Jégou, A., Romet-Lemonne, G., Groves, J. T., Sheetz, M. P., Yan, J. & Bershadsky, A. D., Dec 1 2019, In: Nature communications. 10, 1, 3593.Research output: Contribution to journal › Article › peer-review
Open Access13 Scopus citations -
Steps in Mechanotransduction Pathways that Control Cell Morphology
Wolfenson, H., Yang, B. & Sheetz, M. P., Feb 10 2019, In: Annual review of physiology. 81, p. 585-605 21 p.Research output: Contribution to journal › Review article › peer-review
37 Scopus citations -
2018
Cardiomyocytes Sense Matrix Rigidity through a Combination of Muscle and Non-muscle Myosin Contractions
Pandey, P., Hawkes, W., Hu, J., Megone, W. V., Gautrot, J., Anilkumar, N., Zhang, M., Hirvonen, L., Cox, S., Ehler, E., Hone, J., Sheetz, M. & Iskratsch, T., Feb 5 2018, In: Developmental cell. 44, 3, p. 326-336.e3Research output: Contribution to journal › Article › peer-review
Open Access38 Scopus citations -
Correction to: Energy-dependent nucleolar localization of p53 in vitro requires two discrete regions within the p53 carboxyl terminus (Oncogene, (2007), 26, 26, (3878-3891), 10.1038/sj.onc.1210162)
Karni-Schmidt, O., Friedler, A., Zupnick, A., McKinney, K., Mattia, M., Beckerman, R., Bouvet, P., Sheetz, M., Fersht, A. & Prives, C., Aug 30 2018, In: Oncogene. 37, 35, p. 4901-4902 2 p.Research output: Contribution to journal › Comment/debate › peer-review
Open Access -
EGFR family and Src family kinase interactions: mechanics matters?
Chen, Z., Oh, D., Dubey, A. K., Yao, M., Yang, B., Groves, J. T. & Sheetz, M., Apr 1 2018, In: Current Opinion in Cell Biology. 51, p. 97-102 6 p.Research output: Contribution to journal › Review article › peer-review
19 Scopus citations -
Erratum: Cardiomyocytes Sense Matrix Rigidity through a Combination of Muscle and Non-muscle Myosin Contractions (Developmental cell (2018) 44 3 (326-336.e3) PII: S1534-5807(18)30409-X)
Pandey, P., Hawkes, W., Hu, J., Megone, W. V., Gautrot, J., Anilkumar, N., Zhang, M., Hirvonen, L., Cox, S., Ehler, E., Hone, J., Sheetz, M. & Iskratsch, T., Jun 4 2018, In: Developmental cell. 45, 5, 1 p.Research output: Contribution to journal › Comment/debate › peer-review
Open Access3 Scopus citations -
Full control of ligand positioning reveals spatial thresholds for T cell receptor triggering
Cai, H., Muller, J., Depoil, D., Mayya, V., Sheetz, M. P., Dustin, M. L. & Wind, S. J., Jul 1 2018, In: Nature Nanotechnology. 13, 7, p. 610-617 8 p.Research output: Contribution to journal › Article › peer-review
39 Scopus citations -
2016
Actin polymerization-dependent activation of Cas-L promotes immunological synapse stability
Santos, L. C., Blair, D. A., Kumari, S., Cammer, M., Iskratsch, T., Herbin, O., Alexandropoulos, K., Dustin, M. L. & Sheetz, M. P., Nov 1 2016, In: Immunology and Cell Biology. 94, 10, p. 981-993 13 p.Research output: Contribution to journal › Article › peer-review
Open Access18 Scopus citations -
Cell contractility arising from topography and shear flow determines human mesenchymal stem cell fate
Sonam, S., Sathe, S. R., Yim, E. K. F., Sheetz, M. P. & Lim, C. T., Feb 16 2016, In: Scientific reports. 6, 20415.Research output: Contribution to journal › Article › peer-review
Open Access35 Scopus citations -
Cooperative vinculin binding to talin mapped by time-resolved super resolution microscopy
Hu, X., Jing, C., Xu, X., Nakazawa, N., Cornish, V. W., Margadant, F. M. & Sheetz, M. P., Jul 13 2016, In: Nano Letters. 16, 7, p. 4062-4068 7 p.Research output: Contribution to journal › Article › peer-review
Open Access20 Scopus citations -
F-actin waves, actin cortex disassembly and focal exocytosis driven by actin-phosphoinositide positive feedback
Masters, T. A., Sheetz, M. & Gauthier, N. C., Apr 1 2016, In: Cytoskeleton. 73, 4, p. 180-196 17 p.Research output: Contribution to journal › Article › peer-review
11 Scopus citations -
Formin DAAM1 organizes actin filaments in the cytoplasmic nodal actin network
Luo, W., Lieu, Z. Z., Manser, E., Bershadsky, A. D. & Sheetz, M. P., Oct 2016, In: PloS one. 11, 10, e0163915.Research output: Contribution to journal › Article › peer-review
Open Access10 Scopus citations -
High-Throughput Mechanobiology Screening Platform Using Micro- and Nanotopography
Hu, J., Gondarenko, A. A., Dang, A. P., Bashour, K. T., O'Connor, R. S., Lee, S., Liapis, A., Ghassemi, S., Milone, M. C., Sheetz, M. P., Dustin, M. L., Kam, L. C. & Hone, J. C., Apr 13 2016, In: Nano Letters. 16, 4, p. 2198-2204 7 p.Research output: Contribution to journal › Article › peer-review
22 Scopus citations -
Matrix mechanics controls FHL2 movement to the nucleus to activate p21 expression
Nakazawa, N., Sathe, A. R., Shivashankar, G. V. & Sheetz, M. P., Nov 1 2016, In: Proceedings of the National Academy of Sciences of the United States of America. 113, 44, p. E6813-E6822Research output: Contribution to journal › Article › peer-review
Open Access24 Scopus citations -
Mechanical confinement triggers glioma linear migration dependent on formin FHOD3
Monzo, P., Chong, Y. K., Guetta-Terrier, C., Krishnasamy, A., Sathe, S. R., Yim, E. K. F., Ng, W. H., Ang, B. T., Tang, C., Ladoux, B., Gauthier, N. C. & Sheetz, M. P., Apr 15 2016, In: Molecular Biology of the Cell. 27, 8, p. 1246-1261 16 p.Research output: Contribution to journal › Article › peer-review
27 Scopus citations -
Mechanosensing Controlled Directly by Tyrosine Kinases
Yang, B., Lieu, Z. Z., Wolfenson, H., Hameed, F. M., Bershadsky, A. D. & Sheetz, M. P., Sep 14 2016, In: Nano Letters. 16, 9, p. 5951-5961 11 p.Research output: Contribution to journal › Article › peer-review
45 Scopus citations -
Molecular Occupancy of Nanodot Arrays
Cai, H., Wolfenson, H., Depoil, D., Dustin, M. L., Sheetz, M. P. & Wind, S. J., Apr 26 2016, In: ACS Nano. 10, 4, p. 4173-4183 11 p.Research output: Contribution to journal › Article › peer-review
18 Scopus citations -
Nuclear transport of paxillin depends on focal adhesion dynamics and FAT domains
Sathe, A. R., Shivashankar, G. V. & Sheetz, M. P., May 15 2016, In: Journal of Cell Science. 129, 10, p. 1981-1988 8 p.Research output: Contribution to journal › Article › peer-review
Open Access15 Scopus citations -
The mechanical response of talin
Yao, M., Goult, B. T., Klapholz, B., Hu, X., Toseland, C. P., Guo, Y., Cong, P., Sheetz, M. P. & Yan, J., Jul 7 2016, In: Nature communications. 7, 11966.Research output: Contribution to journal › Article › peer-review
Open Access124 Scopus citations -
Tropomyosin controls sarcomere-like contractions for rigidity sensing and suppressing growth on soft matrices
Wolfenson, H., Meacci, G., Liu, S., Stachowiak, M. R., Iskratsch, T., Ghassemi, S., Roca-Cusachs, P., O'Shaughnessy, B., Hone, J. & Sheetz, M. P., Jan 1 2016, In: Nature Cell Biology. 18, 1, p. 33-42 10 p.Research output: Contribution to journal › Article › peer-review
89 Scopus citations -
α-Actinin links extracellular matrix rigidity-sensing contractile units with periodic cell-edge retractions
Meacci, G., Wolfenson, H., Liu, S., Stachowiak, M. R., Iskratsch, T., Mathur, A., Ghassemi, S., Gauthier, N., Tabdanov, E., Lohner, J., Gondarenko, A., Chander, A. C., Roca-Cusachs, P., O'Shaughnessy, B., Hone, J. & Sheetz, M. P., Nov 7 2016, In: Molecular Biology of the Cell. 27, 22, p. 3471-3479 9 p.Research output: Contribution to journal › Article › peer-review
38 Scopus citations -
2015
Cyclic stretching of soft substrates induces spreading and growth
Cui, Y., Hameed, F. M., Yang, B., Lee, K., Pan, C. Q., Park, S. & Sheetz, M., Feb 23 2015, In: Nature communications. 6, 6333.Research output: Contribution to journal › Article › peer-review
Open Access130 Scopus citations -
Integrin-beta3 clusters recruit clathrin-mediated endocytic machinery in the absence of traction force
Yu, C. H., Rafiq, N. B. M., Cao, F., Zhou, Y., Krishnasamy, A., Biswas, K. H., Ravasio, A., Chen, Z., Wang, Y. H., Kawauchi, K., Jones, G. E. & Sheetz, M. P., Oct 28 2015, In: Nature communications. 6, 8672.Research output: Contribution to journal › Article › peer-review
Open Access41 Scopus citations -
Mechanobiology
Shivashankar, G. V., Sheetz, M. & Matsudaira, P., Oct 1 2015, In: Integrative Biology (United Kingdom). 7, 10, p. 1091-1092 2 p.Research output: Contribution to journal › Editorial › peer-review
6 Scopus citations -
Micropatterning of TCR and LFA-1 ligands reveals complementary effects on cytoskeleton mechanics in T cells
Tabdanov, E., Gondarenko, S., Kumari, S., Liapis, A., Dustin, M. L., Sheetz, M. P., Kam, L. C. & Iskratsch, T., Oct 1 2015, In: Integrative Biology (United Kingdom). 7, 10, p. 1272-1284 13 p.Research output: Contribution to journal › Article › peer-review
Open Access39 Scopus citations -
Nascent Integrin Adhesions Form on All Matrix Rigidities after Integrin Activation
Changede, R., Xu, X., Margadant, F. & Sheetz, M. P., 2015, In: Developmental cell. 35, 5, p. 614-621 8 p.Research output: Contribution to journal › Article › peer-review
Open Access60 Scopus citations -
Parallel near-field photolithography with metal-coated elastomeric masks
Wu, J., Yu, C. H., Li, S., Zou, B., Liu, Y., Zhu, X., Guo, Y., Xu, H., Zhang, W., Zhang, L., Liu, B., Tian, D., Huang, W., Sheetz, M. & Huo, F., Jan 27 2015, In: Langmuir. 31, 3, p. 1210-1217 8 p.Research output: Contribution to journal › Article › peer-review
19 Scopus citations -
Talin Dependent Mechanosensitivity of Cell Focal Adhesions
Yan, J., Yao, M., Goult, B. T. & Sheetz, M. P., Mar 2015, In: Cellular and Molecular Bioengineering. 8, 1, p. 151-159 9 p.Research output: Contribution to journal › Review article › peer-review
Open Access49 Scopus citations -
2014
Appreciating force and shape-the rise of mechanotransduction in cell biology
Iskratsch, T., Wolfenson, H. & Sheetz, M. P., Dec 11 2014, In: Nature Reviews Molecular Cell Biology. 15, 12, p. 825-833 9 p.Research output: Contribution to journal › Review article › peer-review
315 Scopus citations -
Can small institutes address some problems facing biomedical researchers?
Sheetz, M., Nov 1 2014, In: Molecular Biology of the Cell. 25, 21, p. 3267-3269 3 p.Research output: Contribution to journal › Short survey › peer-review
2 Scopus citations -
Early events in cell spreading as a model for quantitative analysis of biomechanical events
Wolfenson, H., Iskratsch, T. & Sheetz, M. P., Dec 2 2014, In: Biophysical journal. 107, 11, p. 2508-2514 7 p.Research output: Contribution to journal › Review article › peer-review
Open Access25 Scopus citations -
Mechanical activation of vinculin binding to talin locks talin in an unfolded conformation
Yao, M., Goult, B. T., Chen, H., Cong, P., Sheetz, M. P. & Yan, J., Apr 9 2014, In: Scientific reports. 4, 4610.Research output: Contribution to journal › Article › peer-review
Open Access165 Scopus citations -
N-WASP-directed actin polymerization activates Cas phosphorylation and lamellipodium spreading
Zhang, X., Moore, S. W., Iskratsch, T. & Sheetz, M. P., Apr 2014, In: Journal of Cell Science. 127, 7, p. 1394-1405 12 p.Research output: Contribution to journal › Article › peer-review
Open Access22 Scopus citations -
Uncovering the mechanism of trapping and cell orientation during Neisseria gonorrhoeae twitching motility
Zaburdaev, V., Biais, N., Schmiedeberg, M., Eriksson, J., Jonsson, A. B., Sheetz, M. P. & Weitz, D. A., Oct 7 2014, In: Biophysical journal. 107, 7, p. 1523-1531 9 p.Research output: Contribution to journal › Article › peer-review
Open Access29 Scopus citations -
YAP/TAZ as mechanosensors and mechanotransducers in regulating organ size and tumor growth
Low, B. C., Pan, C. Q., Shivashankar, G. V., Bershadsky, A., Sudol, M. & Sheetz, M., Aug 19 2014, In: FEBS Letters. 588, 16, p. 2663-2670 8 p.Research output: Contribution to journal › Review article › peer-review
Open Access216 Scopus citations -
2011
Biophysics of substrate interaction: Influence on neural motility, differentiation, and repair
Moore, S. W. & Sheetz, M. P., Nov 2011, In: Developmental Neurobiology. 71, 11, p. 1090-1101 12 p.Research output: Contribution to journal › Article › peer-review
54 Scopus citations -
Cellular mechanotransduction: Filamin A strains to regulate motility
Lynch, C. D. & Sheetz, M. P., Nov 22 2011, In: Current Biology. 21, 22, p. R916-R918Research output: Contribution to journal › Short survey › peer-review
Open Access6 Scopus citations -
Controlled confinement of DNA at the nanoscale: nanofabrication and surface bio-functionalization.
Palma, M., Abramson, J. J., Gorodetsky, A. A., Nuckolls, C., Sheetz, M. P., Wind, S. J. & Hone, J., 2011, In: Methods in molecular biology (Clifton, N.J.). 749, p. 169-185 17 p.Research output: Contribution to journal › Article › peer-review
7 Scopus citations -
Differential mechanical stability of filamin A rod segments
Chen, H., Zhu, X., Cong, P., Sheetz, M. P., Nakamura, F. & Yan, J., Sep 7 2011, In: Biophysical journal. 101, 5, p. 1231-1237 7 p.Research output: Contribution to journal › Article › peer-review
Open Access34 Scopus citations -
Early integrin binding to Arg-Gly-Asp peptide activates actin polymerization and contractile movement that stimulates outward translocation
Yu, C. H., Law, J. B. K., Suryana, M., Low, H. Y. & Sheetz, M. P., Dec 20 2011, In: Proceedings of the National Academy of Sciences of the United States of America. 108, 51, p. 20585-20590 6 p.Research output: Contribution to journal › Article › peer-review
Open Access131 Scopus citations -
Filamin depletion blocks endoplasmic spreading and destabilizes force-bearing adhesions
Lynch, C. D., Gauthier, N. C., Biais, N., Lazar, A. M., Roca-Cusachs, P., Yu, C. H. & Sheetz, M. P., Apr 15 2011, In: Molecular Biology of the Cell. 22, 8, p. 1263-1273 11 p.Research output: Contribution to journal › Article › peer-review
44 Scopus citations -
Mechanotransduction in vivo by repeated talin stretch-relaxation events depends upon vinculin
Margadant, F., Chew, L. L., Hu, X., Yu, H., Bate, N., Zhang, X. & Sheetz, M., Dec 2011, In: PLoS Biology. 9, 12, e1001223.Research output: Contribution to journal › Article › peer-review
Open Access133 Scopus citations -
Nanolithographic control of the spatial organization of cellular adhesion receptors at the single-molecule level
Schvartzman, M., Palma, M., Sable, J., Abramson, J., Hu, X., Sheetz, M. P. & Wind, S. J., Mar 9 2011, In: Nano Letters. 11, 3, p. 1306-1312 7 p.Research output: Contribution to journal › Article › peer-review
155 Scopus citations -
New approach for measuring protrusive forces in cells
Mathur, A., Roca-Cusachs, P., Rossier, O. M., Wind, S. J., Sheetz, M. P. & Hone, J., Nov 2011, In: Journal of Vacuum Science and Technology B:Nanotechnology and Microelectronics. 29, 6, 06FA02.Research output: Contribution to journal › Article › peer-review
3 Scopus citations -
Selective biomolecular nanoarrays for parallel single-molecule investigations
Palma, M., Abramson, J. J., Gorodetsky, A. A., Penzo, E., Gonzalez, R. L., Sheetz, M. P., Nuckolls, C., Hone, J. & Wind, S. J., May 25 2011, In: Journal of the American Chemical Society. 133, 20, p. 7656-7659 4 p.Research output: Contribution to journal › Article › peer-review
33 Scopus citations -
Signaling network triggers and membrane physical properties control the actin cytoskeleton-driven isotropic phase of cell spreading
Rangamani, P., Fardin, M. A., Xiong, Y., Lipshtat, A., Rossier, O., Sheetz, M. P. & Iyengar, R., Feb 16 2011, In: Biophysical journal. 100, 4, p. 845-857 13 p.Research output: Contribution to journal › Article › peer-review
Open Access22 Scopus citations