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2020
Cell response to substrate rigidity is regulated by active and passive cytoskeletal stress
Doss, B. L., Pan, M., Gupta, M., Grenci, G., Mège, R. M., Lim, C. T., Sheetz, M. P., Voituriez, R. & Ladoux, B., Jun 9 2020, In: Proceedings of the National Academy of Sciences of the United States of America. 117, 23, p. 12817-12825 9 p.Research output: Contribution to journal › Article › peer-review
5 Scopus citations -
Micro-stepping extended focus reduces photobleaching and preserves structured illumination super-resolution features
Hu, X., Jalal, S., Sheetz, M., Bakke, O. & Margadant, F., May 2020, In: Journal of Cell Science. 133, 10, 240796.Research output: Contribution to journal › Article › peer-review
Open Access -
Stopping transformed cancer cell growth by rigidity sensing
Yang, B., Wolfenson, H., Chung, V. Y., Nakazawa, N., Liu, S., Hu, J., Huang, R. Y. J. & Sheetz, M. P., Feb 1 2020, In: Nature Materials. 19, 2, p. 239-250 12 p.Research output: Contribution to journal › Article › peer-review
9 Scopus citations -
2019
A tale of two states: Normal and transformed, with and without rigidity sensing
Sheetz, M., 2019, In: Annual Review of Cell and Developmental Biology. 35, p. 169-190 22 p.Research output: Contribution to journal › Review article › peer-review
3 Scopus citations -
Integrin Mechano-chemical Signaling Generates Plasma Membrane Nanodomains that Promote Cell Spreading
Kalappurakkal, J. M., Anilkumar, A. A., Patra, C., van Zanten, T. S., Sheetz, M. P. & Mayor, S., Jun 13 2019, In: Cell. 177, 7, p. 1738-1756.e23Research output: Contribution to journal › Article › peer-review
Open Access24 Scopus citations -
Integrin nanoclusters can bridge thin matrix fibres to form cell–matrix adhesions
Changede, R., Cai, H., Wind, S. J. & Sheetz, M. P., Dec 1 2019, In: Nature Materials. 18, 12, p. 1366-1375 10 p.Research output: Contribution to journal › Article › peer-review
20 Scopus citations -
Large and reversible myosin-dependent forces in rigidity sensing
Lohner, J., Rupprecht, J. F., Hu, J., Mandriota, N., Saxena, M., de Araujo, D. P., Hone, J., Sahin, O., Prost, J. & Sheetz, M., Jul 1 2019, In: Nature Physics. 15, 7, p. 689-695 7 p.Research output: Contribution to journal › Article › peer-review
9 Scopus citations -
Myosin IIA and formin dependent mechanosensitivity of filopodia adhesion
Alieva, N. O., Efremov, A. K., Hu, S., Oh, D., Chen, Z., Natarajan, M., Ong, H. T., Jégou, A., Romet-Lemonne, G., Groves, J. T., Sheetz, M. P., Yan, J. & Bershadsky, A. D., Dec 1 2019, In: Nature communications. 10, 1, 3593.Research output: Contribution to journal › Article › peer-review
Open Access12 Scopus citations -
Steps in Mechanotransduction Pathways that Control Cell Morphology
Wolfenson, H., Yang, B. & Sheetz, M. P., Feb 10 2019, In: Annual review of physiology. 81, p. 585-605 21 p.Research output: Contribution to journal › Review article › peer-review
34 Scopus citations -
2018
Cardiomyocytes Sense Matrix Rigidity through a Combination of Muscle and Non-muscle Myosin Contractions
Pandey, P., Hawkes, W., Hu, J., Megone, W. V., Gautrot, J., Anilkumar, N., Zhang, M., Hirvonen, L., Cox, S., Ehler, E., Hone, J., Sheetz, M. & Iskratsch, T., Feb 5 2018, In: Developmental cell. 44, 3, p. 326-336.e3Research output: Contribution to journal › Article › peer-review
Open Access36 Scopus citations -
Correction to: Energy-dependent nucleolar localization of p53 in vitro requires two discrete regions within the p53 carboxyl terminus (Oncogene, (2007), 26, 26, (3878-3891), 10.1038/sj.onc.1210162)
Karni-Schmidt, O., Friedler, A., Zupnick, A., McKinney, K., Mattia, M., Beckerman, R., Bouvet, P., Sheetz, M., Fersht, A. & Prives, C., Aug 30 2018, In: Oncogene. 37, 35, p. 4901-4902 2 p.Research output: Contribution to journal › Comment/debate › peer-review
Open Access -
EGFR family and Src family kinase interactions: mechanics matters?
Chen, Z., Oh, D., Dubey, A. K., Yao, M., Yang, B., Groves, J. T. & Sheetz, M., Apr 1 2018, In: Current Opinion in Cell Biology. 51, p. 97-102 6 p.Research output: Contribution to journal › Review article › peer-review
18 Scopus citations -
Erratum: Cardiomyocytes Sense Matrix Rigidity through a Combination of Muscle and Non-muscle Myosin Contractions (Developmental cell (2018) 44 3 (326-336.e3) PII: S1534-5807(18)30409-X)
Pandey, P., Hawkes, W., Hu, J., Megone, W. V., Gautrot, J., Anilkumar, N., Zhang, M., Hirvonen, L., Cox, S., Ehler, E., Hone, J., Sheetz, M. & Iskratsch, T., Jun 4 2018, In: Developmental cell. 45, 5, 1 p.Research output: Contribution to journal › Comment/debate › peer-review
Open Access3 Scopus citations -
Full control of ligand positioning reveals spatial thresholds for T cell receptor triggering
Cai, H., Muller, J., Depoil, D., Mayya, V., Sheetz, M. P., Dustin, M. L. & Wind, S. J., Jul 1 2018, In: Nature Nanotechnology. 13, 7, p. 610-617 8 p.Research output: Contribution to journal › Article › peer-review
36 Scopus citations -
2017
DNA damage causes rapid accumulation of phosphoinositides for ATR signaling
Wang, Y. H., Hariharan, A., Bastianello, G., Toyama, Y., Shivashankar, G. V., Foiani, M. & Sheetz, M. P., Dec 1 2017, In: Nature communications. 8, 1, 2118.Research output: Contribution to journal › Article › peer-review
Open Access27 Scopus citations -
EGFR and HER2 activate rigidity sensing only on rigid matrices
Saxena, M., Liu, S., Yang, B., Hajal, C., Changede, R., Hu, J., Wolfenson, H., Hone, J. & Sheetz, M. P., Jul 1 2017, In: Nature Materials. 16, 7, p. 775-781 7 p.Research output: Contribution to journal › Article › peer-review
33 Scopus citations -
Force-Induced Calpain Cleavage of Talin Is Critical for Growth, Adhesion Development, and Rigidity Sensing
Saxena, M., Changede, R., Hone, J., Wolfenson, H. & Sheetz, M. P., Dec 13 2017, In: Nano Letters. 17, 12, p. 7242-7251 10 p.Research output: Contribution to journal › Article › peer-review
21 Scopus citations -
Integrin and cadherin clusters: A robust way to organize adhesions for cell mechanics
Changede, R. & Sheetz, M., Jan 1 2017, In: BioEssays. 39, 1, p. 1-12 12 p.Research output: Contribution to journal › Article › peer-review
Open Access42 Scopus citations -
MDia1 senses both force and torque during F-actin filament polymerization
Yu, M., Yuan, X., Lu, C., Le, S., Kawamura, R., Efremov, A. K., Zhao, Z., Kozlov, M. M., Sheetz, M., Bershadsky, A. & Yan, J., Dec 1 2017, In: Nature communications. 8, 1, 1650.Research output: Contribution to journal › Article › peer-review
Open Access36 Scopus citations -
Mechanotransmission and Mechanosensing of Human alpha-Actinin 1
Le, S., Hu, X., Yao, M., Chen, H., Yu, M., Xu, X., Nakazawa, N., Margadant, F. M., Sheetz, M. P. & Yan, J., Dec 5 2017, In: Cell Reports. 21, 10, p. 2714-2723 10 p.Research output: Contribution to journal › Article › peer-review
Open Access25 Scopus citations -
Molecular stretching modulates mechanosensing pathways
Hu, X., Margadant, F. M., Yao, M. & Sheetz, M. P., Jul 1 2017, In: Protein Science. 26, 7, p. 1337-1351 15 p.Research output: Contribution to journal › Review article › peer-review
23 Scopus citations -
Polymer fiber-based models of connective tissue repair and healing
Lee, N. M., Erisken, C., Iskratsch, T., Sheetz, M., Levine, W. N. & Lu, H. H., Jan 1 2017, In: Biomaterials. 112, p. 303-312 10 p.Research output: Contribution to journal › Article › peer-review
35 Scopus citations -
Spatial control of biological ligands on surfaces applied to T cell activation
Cai, H., Depoil, D., Muller, J., Sheetz, M. P., Dustin, M. L. & Wind, S. J., 2017, Methods in Molecular Biology. Humana Press Inc., p. 307-331 25 p. (Methods in Molecular Biology; vol. 1584).Research output: Chapter in Book/Report/Conference proceeding › Chapter
2 Scopus citations -
2016
Actin polymerization-dependent activation of Cas-L promotes immunological synapse stability
Santos, L. C., Blair, D. A., Kumari, S., Cammer, M., Iskratsch, T., Herbin, O., Alexandropoulos, K., Dustin, M. L. & Sheetz, M. P., Nov 1 2016, In: Immunology and Cell Biology. 94, 10, p. 981-993 13 p.Research output: Contribution to journal › Article › peer-review
Open Access18 Scopus citations -
Cell contractility arising from topography and shear flow determines human mesenchymal stem cell fate
Sonam, S., Sathe, S. R., Yim, E. K. F., Sheetz, M. P. & Lim, C. T., Feb 16 2016, In: Scientific reports. 6, 20415.Research output: Contribution to journal › Article › peer-review
Open Access35 Scopus citations -
Cooperative vinculin binding to talin mapped by time-resolved super resolution microscopy
Hu, X., Jing, C., Xu, X., Nakazawa, N., Cornish, V. W., Margadant, F. M. & Sheetz, M. P., Jul 13 2016, In: Nano Letters. 16, 7, p. 4062-4068 7 p.Research output: Contribution to journal › Article › peer-review
Open Access20 Scopus citations -
F-actin waves, actin cortex disassembly and focal exocytosis driven by actin-phosphoinositide positive feedback
Masters, T. A., Sheetz, M. & Gauthier, N. C., Apr 1 2016, In: Cytoskeleton. 73, 4, p. 180-196 17 p.Research output: Contribution to journal › Article › peer-review
11 Scopus citations -
Formin DAAM1 organizes actin filaments in the cytoplasmic nodal actin network
Luo, W., Lieu, Z. Z., Manser, E., Bershadsky, A. D. & Sheetz, M. P., Oct 2016, In: PloS one. 11, 10, e0163915.Research output: Contribution to journal › Article › peer-review
Open Access10 Scopus citations -
High-Throughput Mechanobiology Screening Platform Using Micro- and Nanotopography
Hu, J., Gondarenko, A. A., Dang, A. P., Bashour, K. T., O'Connor, R. S., Lee, S., Liapis, A., Ghassemi, S., Milone, M. C., Sheetz, M. P., Dustin, M. L., Kam, L. C. & Hone, J. C., Apr 13 2016, In: Nano Letters. 16, 4, p. 2198-2204 7 p.Research output: Contribution to journal › Article › peer-review
22 Scopus citations -
Matrix mechanics controls FHL2 movement to the nucleus to activate p21 expression
Nakazawa, N., Sathe, A. R., Shivashankar, G. V. & Sheetz, M. P., Nov 1 2016, In: Proceedings of the National Academy of Sciences of the United States of America. 113, 44, p. E6813-E6822Research output: Contribution to journal › Article › peer-review
Open Access24 Scopus citations -
Mechanical confinement triggers glioma linear migration dependent on formin FHOD3
Monzo, P., Chong, Y. K., Guetta-Terrier, C., Krishnasamy, A., Sathe, S. R., Yim, E. K. F., Ng, W. H., Ang, B. T., Tang, C., Ladoux, B., Gauthier, N. C. & Sheetz, M. P., Apr 15 2016, In: Molecular Biology of the Cell. 27, 8, p. 1246-1261 16 p.Research output: Contribution to journal › Article › peer-review
27 Scopus citations -
Mechanosensing Controlled Directly by Tyrosine Kinases
Yang, B., Lieu, Z. Z., Wolfenson, H., Hameed, F. M., Bershadsky, A. D. & Sheetz, M. P., Sep 14 2016, In: Nano Letters. 16, 9, p. 5951-5961 11 p.Research output: Contribution to journal › Article › peer-review
44 Scopus citations -
Molecular Occupancy of Nanodot Arrays
Cai, H., Wolfenson, H., Depoil, D., Dustin, M. L., Sheetz, M. P. & Wind, S. J., Apr 26 2016, In: ACS Nano. 10, 4, p. 4173-4183 11 p.Research output: Contribution to journal › Article › peer-review
18 Scopus citations -
Nuclear transport of paxillin depends on focal adhesion dynamics and FAT domains
Sathe, A. R., Shivashankar, G. V. & Sheetz, M. P., May 15 2016, In: Journal of Cell Science. 129, 10, p. 1981-1988 8 p.Research output: Contribution to journal › Article › peer-review
Open Access14 Scopus citations -
The mechanical response of talin
Yao, M., Goult, B. T., Klapholz, B., Hu, X., Toseland, C. P., Guo, Y., Cong, P., Sheetz, M. P. & Yan, J., Jul 7 2016, In: Nature communications. 7, 11966.Research output: Contribution to journal › Article › peer-review
Open Access121 Scopus citations -
Tropomyosin controls sarcomere-like contractions for rigidity sensing and suppressing growth on soft matrices
Wolfenson, H., Meacci, G., Liu, S., Stachowiak, M. R., Iskratsch, T., Ghassemi, S., Roca-Cusachs, P., O'Shaughnessy, B., Hone, J. & Sheetz, M. P., Jan 1 2016, In: Nature Cell Biology. 18, 1, p. 33-42 10 p.Research output: Contribution to journal › Article › peer-review
87 Scopus citations -
α-Actinin links extracellular matrix rigidity-sensing contractile units with periodic cell-edge retractions
Meacci, G., Wolfenson, H., Liu, S., Stachowiak, M. R., Iskratsch, T., Mathur, A., Ghassemi, S., Gauthier, N., Tabdanov, E., Lohner, J., Gondarenko, A., Chander, A. C., Roca-Cusachs, P., O'Shaughnessy, B., Hone, J. & Sheetz, M. P., Nov 7 2016, In: Molecular Biology of the Cell. 27, 22, p. 3471-3479 9 p.Research output: Contribution to journal › Article › peer-review
38 Scopus citations -
2015
Cyclic stretching of soft substrates induces spreading and growth
Cui, Y., Hameed, F. M., Yang, B., Lee, K., Pan, C. Q., Park, S. & Sheetz, M., Feb 23 2015, In: Nature communications. 6, 6333.Research output: Contribution to journal › Article › peer-review
Open Access128 Scopus citations -
Integrin-beta3 clusters recruit clathrin-mediated endocytic machinery in the absence of traction force
Yu, C. H., Rafiq, N. B. M., Cao, F., Zhou, Y., Krishnasamy, A., Biswas, K. H., Ravasio, A., Chen, Z., Wang, Y. H., Kawauchi, K., Jones, G. E. & Sheetz, M. P., Oct 28 2015, In: Nature communications. 6, 8672.Research output: Contribution to journal › Article › peer-review
Open Access41 Scopus citations -
Mechanobiology
Shivashankar, G. V., Sheetz, M. & Matsudaira, P., Oct 1 2015, In: Integrative Biology (United Kingdom). 7, 10, p. 1091-1092 2 p.Research output: Contribution to journal › Editorial › peer-review
5 Scopus citations -
Micropatterning of TCR and LFA-1 ligands reveals complementary effects on cytoskeleton mechanics in T cells
Tabdanov, E., Gondarenko, S., Kumari, S., Liapis, A., Dustin, M. L., Sheetz, M. P., Kam, L. C. & Iskratsch, T., Oct 1 2015, In: Integrative Biology (United Kingdom). 7, 10, p. 1272-1284 13 p.Research output: Contribution to journal › Article › peer-review
Open Access39 Scopus citations -
Nascent Integrin Adhesions Form on All Matrix Rigidities after Integrin Activation
Changede, R., Xu, X., Margadant, F. & Sheetz, M. P., 2015, In: Developmental cell. 35, 5, p. 614-621 8 p.Research output: Contribution to journal › Article › peer-review
Open Access58 Scopus citations -
Parallel near-field photolithography with metal-coated elastomeric masks
Wu, J., Yu, C. H., Li, S., Zou, B., Liu, Y., Zhu, X., Guo, Y., Xu, H., Zhang, W., Zhang, L., Liu, B., Tian, D., Huang, W., Sheetz, M. & Huo, F., Jan 27 2015, In: Langmuir. 31, 3, p. 1210-1217 8 p.Research output: Contribution to journal › Article › peer-review
19 Scopus citations -
Talin Dependent Mechanosensitivity of Cell Focal Adhesions
Yan, J., Yao, M., Goult, B. T. & Sheetz, M. P., 2015, In: Cellular and Molecular Bioengineering. 8, 1, p. 151-159 9 p.Research output: Contribution to journal › Review article › peer-review
Open Access49 Scopus citations -
2011
Biophysics of substrate interaction: Influence on neural motility, differentiation, and repair
Moore, S. W. & Sheetz, M. P., Nov 2011, In: Developmental Neurobiology. 71, 11, p. 1090-1101 12 p.Research output: Contribution to journal › Article › peer-review
53 Scopus citations -
Cellular mechanotransduction: Filamin A strains to regulate motility
Lynch, C. D. & Sheetz, M. P., Nov 22 2011, In: Current Biology. 21, 22, p. R916-R918Research output: Contribution to journal › Short survey › peer-review
Open Access6 Scopus citations -
Controlled confinement of DNA at the nanoscale: nanofabrication and surface bio-functionalization.
Palma, M., Abramson, J. J., Gorodetsky, A. A., Nuckolls, C., Sheetz, M. P., Wind, S. J. & Hone, J., 2011, In: Methods in molecular biology (Clifton, N.J.). 749, p. 169-185 17 p.Research output: Contribution to journal › Article › peer-review
7 Scopus citations -
Differential mechanical stability of filamin A rod segments
Chen, H., Zhu, X., Cong, P., Sheetz, M. P., Nakamura, F. & Yan, J., Sep 7 2011, In: Biophysical journal. 101, 5, p. 1231-1237 7 p.Research output: Contribution to journal › Article › peer-review
Open Access34 Scopus citations -
Early integrin binding to Arg-Gly-Asp peptide activates actin polymerization and contractile movement that stimulates outward translocation
Yu, C. H., Law, J. B. K., Suryana, M., Low, H. Y. & Sheetz, M. P., Dec 20 2011, In: Proceedings of the National Academy of Sciences of the United States of America. 108, 51, p. 20585-20590 6 p.Research output: Contribution to journal › Article › peer-review
Open Access131 Scopus citations -
Filamin depletion blocks endoplasmic spreading and destabilizes force-bearing adhesions
Lynch, C. D., Gauthier, N. C., Biais, N., Lazar, A. M., Roca-Cusachs, P., Yu, C. H. & Sheetz, M. P., Apr 15 2011, In: Molecular Biology of the Cell. 22, 8, p. 1263-1273 11 p.Research output: Contribution to journal › Article › peer-review
44 Scopus citations