Find Research Outputs

Search results

• 2015

  Permissive and protective roles for neutrophils in leishmaniasis

  Carlsen, E. D., Liang, Y., Shelite, T. R., Walker, D. H., Melby, P. C. & Soong, L., Nov 2015, In: Clinical and Experimental Immunology. 182, 2, p. 109-18 10 p.

  Research output: Contribution to journal › Article › peer-review

  • Leishmaniasis
  • Parasites
  • Neutrophils
  • Leishmania
  • Infection
  32 Scopus citations

• Reemergence of murine typhus in galveston, texas, usa, 2013

  Blanton, L. S., Vohra, R. F., Bouyer, D. H. & Walker, D. H., 2015, In: Emerging infectious diseases. 21, 3, p. 484-486 3 p.

  Research output: Contribution to journal › Article › peer-review

  • Endemic Flea-Borne Typhus
  • Rickettsia typhi
  • Public Health
  • Physicians
  24 Scopus citations

• Rickettsia massiliae and rickettsia conorii israeli spotted fever strain differentially regulate endothelial cell responses

  Bechelli, J., Smalley, C., Milhano, N., Walker, D. H. & Fang, R., Sep 22 2015, In: PloS one. 10, 9, e0138830.

  Research output: Contribution to journal › Article › peer-review

  • Rickettsia massiliae
  • Rickettsia conorii
  • Spotted Fever Group Rickettsiosis
  • Endothelial cells
  • Rickettsia
  5 Scopus citations

• The role of CD8 T lymphocytes in rickettsial infections

  Walker, D. H. & Dumler, J. S., May 26 2015, In: Seminars in Immunopathology. 37, 3, p. 289-299 11 p.

  Research output: Contribution to journal › Review article › peer-review

  • T-Lymphocytes
  • Infection
  • Anaplasmosis
  • Ehrlichiosis
  • Immunity
  17 Scopus citations

• The role of Rhipicephalus sanguineus sensu lato saliva in the dissemination of Rickettsia conorii in C3H/HeJ mice

  Milhano, N., Saito, T. B., Bechelli, J., Fang, R., Vilhena, M., De Sousa, R. & Walker, D. H., Sep 1 2015, In: Medical and Veterinary Entomology. 29, 3, p. 225-229 5 p.

  Research output: Contribution to journal › Article › peer-review

  • Rickettsia conorii
  • Rhipicephalus sanguineus
  • tick
  • saliva
  • Ticks
  9 Scopus citations
• 2014

  After malaria is controlled, what's next?

  Walker, D. H., Jul 2014, In: American Journal of Tropical Medicine and Hygiene. 91, 1, p. 7-10 4 p.

  Research output: Contribution to journal › Editorial › peer-review
  1 Scopus citations

• A Hematogenously Disseminated Orientia tsutsugamsushi-Infected Murine Model of Scrub Typhus

  Shelite, T. R., Saito, T. B., Mendell, N. L., Gong, B., Xu, G., Soong, L., Valbuena, G., Bouyer, D. H. & Walker, D. H., Jul 2014, In: PLoS neglected tropical diseases. 8, 7, e2966.

  Research output: Contribution to journal › Article › peer-review

  • Scrub Typhus
  • Orientia tsutsugamushi
  • Infection
  • Inbred C57BL Mouse
  • Trombiculidae
  25 Scopus citations

• Diseases Caused by Fungi

  Walker, D. H. & McGinnis, M. R., Jan 1 2014, Pathobiology of Human Disease: A Dynamic Encyclopedia of Disease Mechanisms. Elsevier Inc., p. 217-221 5 p.

  Research output: Chapter in Book/Report/Conference proceeding › Chapter

  • Mycoses
  • Fungi
  • Fungal Structures
  • Histoplasma
  • Arthrodermataceae

• Ehrlichia

  Thirumalapura, N. R. & Walker, D., Nov 26 2014, Molecular Medical Microbiology: Second Edition. Elsevier Ltd, Vol. 3. p. 2011-2032 22 p.

  Research output: Chapter in Book/Report/Conference proceeding › Chapter

  • Ehrlichia
  • Ehrlichiosis
  • Ehrlichia chaffeensis
  • Peptidoglycan
  • Liver

• Ehrlichia chaffeensis (Human Monocytotropic Ehrlichiosis), Anaplasma phagocytophilum (Human Granulocytotropic Anaplasmosis), and Other Anaplasmataceae

  Dumler, J. S. & Walker, D. H., Aug 28 2014, Mandell, Douglas, and Bennett's Principles and Practice of Infectious Diseases. Elsevier Inc., Vol. 2. p. 2227-2233.e3

  Research output: Chapter in Book/Report/Conference proceeding › Chapter
  9 Scopus citations

• Inactivation of sam-methyltransferase is the mechanism of attenuation of a historic louse borne typhus vaccine strain

  Liu, Y., Wu, B., Weinstock, G., Walker, D. H. & Yu, X. J., Nov 20 2014, In: PloS one. 9, 11, e113285.

  Research output: Contribution to journal › Article › peer-review

  • typhus vaccine
  • Rickettsia prowazekii
  • Short Stature, Auditory Canal Atresia, Mandibular Hypoplasia, Skeletal Abnormalities
  • typhus
  • Phthiraptera
  4 Scopus citations

• Interactions of Pathogens with the Host

  Walker, D., Jan 1 2014, Pathobiology of Human Disease: A Dynamic Encyclopedia of Disease Mechanisms. Elsevier Inc., p. 214-216 3 p.

  Research output: Chapter in Book/Report/Conference proceeding › Chapter

  • Host-Pathogen Interactions
  • Infection
  • Meningoencephalitis
  • Asymptomatic Infections
  • Lymphatic Vessels

• Omplete genome sequence of Ehrlichia muris strain AS145^T, a model monocytotropic Ehrlichia strain

  Thirumalapura, N. R., Qin, X., Kuriakose, J. A. & Walker, D., 2014, In: Genome Announcements. 2, 1, e01234-13.

  Research output: Contribution to journal › Article › peer-review

  • Ehrlichia
  • Ehrlichiosis
  • Genome
  • Japan
  • Infection
  5 Scopus citations

• Pathogenesis of Infectious Diseases and Mechanisms of Immunity

  McBride, J. & Walker, D., Dec 9 2014, Vaccinology: An Essential Guide. Wiley Blackwell, p. 59-72 14 p.

  Research output: Chapter in Book/Report/Conference proceeding › Chapter

  • Communicable Diseases
  • Immunity
  • Vaccines
  • Host-Pathogen Interactions
  • Antibodies

• Principles of Diagnosis of Infectious Diseases

  Walker, D., Jan 1 2014, Pathobiology of Human Disease: A Dynamic Encyclopedia of Disease Mechanisms. Elsevier Inc., p. 222-225 4 p.

  Research output: Chapter in Book/Report/Conference proceeding › Chapter

  • Communicable Diseases
  • Inclusion Bodies
  • Viruses
  • Nucleic Acids
  • Fungi

• Quantitative study of Rickettsia massiliae in Rhipicephalus sanguineus organs

  Milhano, N., Popov, V., Vilhena, M., Bouyer, D. H., de Sousa, R. & Walker, D. H., Oct 1 2014, In: Ticks and Tick-borne Diseases. 5, 6, p. 709-714 6 p.

  Research output: Contribution to journal › Article › peer-review

  • Rickettsia massiliae
  • Rhipicephalus sanguineus
  • Rickettsia
  • Ticks
  • ticks
  6 Scopus citations

• "rickettsia amblyommii" Induces cross protection against lethal rocky mountain spotted fever in a guinea pig model

  Blanton, L. S., Mendell, N. L., Walker, D. H. & Bouyer, D. H., Aug 1 2014, In: Vector-Borne and Zoonotic Diseases. 14, 8, p. 557-562 6 p.

  Research output: Contribution to journal › Article › peer-review

  • Rickettsia rickettsii
  • Rocky Mountain Spotted Fever
  • Cross Protection
  • Rickettsia
  • Guinea Pigs
  18 Scopus citations

• Rickettsiae and ehrlichiae within a city park: Is the urban dweller at risk?

  Blanton, L. S., Walker, D. H. & Bouyer, D. H., Feb 1 2014, In: Vector-Borne and Zoonotic Diseases. 14, 2, p. 168-170 3 p.

  Research output: Contribution to journal › Article › peer-review

  • Ehrlichia
  • Ticks
  • Ehrlichiosis
  • Ehrlichia chaffeensis
  • Dermacentor
  13 Scopus citations

• Rickettsia felis and changing paradigms about pathogenic rickettsiae

  Labruna, M. B. & Walker, D. H., Oct 1 2014, In: Emerging infectious diseases. 20, 10, p. 1768-1769 2 p.

  Research output: Contribution to journal › Letter › peer-review
  21 Scopus citations

• Rickettsia prowazekii (Epidemic or Louse-Borne Typhus)

  Blanton, L. S. & Walker, D. H., Aug 28 2014, Mandell, Douglas, and Bennett's Principles and Practice of Infectious Diseases. Elsevier Inc., Vol. 2. p. 2217-2220.e1

  Research output: Chapter in Book/Report/Conference proceeding › Chapter

• Rickettsia rickettsii and Other Spotted Fever Group Rickettsiae (Rocky Mountain Spotted Fever and Other Spotted Fevers)

  Walker, D. H. & Blanton, L. S., Aug 28 2014, Mandell, Douglas, and Bennett's Principles and Practice of Infectious Diseases. Elsevier Inc., Vol. 2. p. 2198-2205 8 p.

  Research output: Chapter in Book/Report/Conference proceeding › Chapter
  4 Scopus citations

• Rickettsia typhi (Murine Typhus)

  Blanton, L. S., Dumler, J. S. & Walker, D. H., Aug 28 2014, Mandell, Douglas, and Bennett's Principles and Practice of Infectious Diseases. Elsevier Inc., Vol. 2. p. 2221-2224.e2

  Research output: Chapter in Book/Report/Conference proceeding › Chapter
  5 Scopus citations

• Strong Type 1, but Impaired Type 2, Immune Responses Contribute to Orientia tsutsugamushi-Induced Pathology in Mice

  Soong, L., Wang, H., Shelite, T. R., Liang, Y., Mendell, N. L., Sun, J., Gong, B., Valbuena, G. A., Bouyer, D. H. & Walker, D. H., Sep 1 2014, In: PLoS neglected tropical diseases. 8, 9

  Research output: Contribution to journal › Article › peer-review

  • Orientia tsutsugamushi
  • Scrub Typhus
  • Angiopoietin-2
  • Pathology
  • Angiopoietin-1
  22 Scopus citations

• The pathogenesis of severe fever with thrombocytopenia syndrome virus infection in alpha/beta interferon knockout mice: Insights into the pathologic mechanisms of a new viral hemorrhagic fever

  Liu, Y., Wu, B., Paessler, S., Walker, D. H., Tesh, R. B. & Yu, X. J., Feb 2014, In: Journal of virology. 88, 3, p. 1781-1786 6 p.

  Research output: Contribution to journal › Article › peer-review

  • Viral Hemorrhagic Fevers
  • interferon-beta
  • thrombocytopenia
  • Interferon-beta
  • Interferon-alpha
  66 Scopus citations
• 2013

  Approaches to vaccines against Orientia tsutsugamushi

  Valbuena, G. & Walker, D. H., 2013, In: Frontiers in cellular and infection microbiology. 4, JAN, Article 170.

  Research output: Contribution to journal › Article › peer-review

  • Orientia tsutsugamushi
  • Scrub Typhus
  • Vaccines
  • Pacific Ocean
  • Northern Asia

• Approaches to vaccines against Orientia tsutsugamushi

  Valbuena, G. & Walker, D. H., 2013, In: Frontiers in Cellular and Infection Microbiology. 4, JAN, Article 170.

  Research output: Contribution to journal › Review article › peer-review

  Open Access

  • Orientia tsutsugamushi
  • Scrub Typhus
  • Vaccines
  • Pacific Ocean
  • Northern Asia
  43 Scopus citations

• Case-Fatality ratio and effectiveness of ribavirin therapy among hospitalized patients in china who had severe fever with thrombocytopenia syndrome

  Liu, W., Lu, Q. B., Cui, N., Li, H., Wang, L. Y., Liu, K., Yang, Z. D., Wang, B. J., Wang, H. Y., Zhang, Y. Y., Zhuang, L., Hu, C. Y., Yuan, C., Fan, X. J., Wang, Z., Zhang, L., Zhang, X. A., Walker, D. H. & Cao, W. C., Nov 1 2013, In: Clinical Infectious Diseases. 57, 9, p. 1292-1299 8 p.

  Research output: Contribution to journal › Article › peer-review

  • Ribavirin
  • Thrombocytopenia
  • China
  • Fever
  • Fatal Outcome
  96 Scopus citations

• Compartmentalized, functional role of angiogenin during spotted fever group rickettsia-induced endothelial barrier dysfunction: Evidence of possible mediation by host tRNA-derived small noncoding RNAs

  Gong, B., Lee, Y. S., Lee, I., Shelite, T. R., Kunkeaw, N., Xu, G., Lee, K., Jeon, S. H., Johnson, B. H., Chang, Q., Ha, T., Mendell, N. L., Cheng, X., Bouyer, D. H., Boor, P. J., Ksiazek, T. G. & Walker, D. H., Jun 23 2013, In: BMC Infectious Diseases. 13, 1, 285.

  Research output: Contribution to journal › Article › peer-review

  • angiogenin
  • Spotted Fever Group Rickettsiosis
  • Rickettsia
  • Small Untranslated RNA
  • Transfer RNA
  25 Scopus citations

• Exchange protein directly activated by cAMP plays a critical role in bacterial invasion during fatal rickettsioses

  Gong, B., Shelite, T., Mei, F. C., Ha, T., Hu, Y., Xu, G., Chang, Q., Wakamiya, M., Ksiazek, T. G., Boor, P. J., Bouyer, D. H., Popov, V. L., Chen, J., Walker, D. H. & Cheng, X., Nov 26 2013, In: Proceedings of the National Academy of Sciences of the United States of America. 110, 48, p. 19615-19620 6 p.

  Research output: Contribution to journal › Article › peer-review

  • 3-(5-tert-butylisoxazol-3-yl)-2-((3-chlorophenyl)hydrazono)-3-oxopropionitrile
  • Spotted Fever Group Rickettsiosis
  • Bioterrorism
  • Bacterial Adhesion
  • Host-Pathogen Interactions
  48 Scopus citations

• Mice lacking functional STAT1 are highly susceptible to lethal infection with Lassa virus

  Yun, N. E., Seregin, A. V., Walker, D. H., Popov, V. L., Walker, A. G., Smith, J. N., Miller, M., de la Torre, J. C., Smith, J. K., Borisevich, V., Fair, J. N., Wauquier, N., Grant, D. S., Bockarie, B., Bente, D. & Paessler, S., 2013, In: Journal of virology. 87, 19, p. 10908-10911 4 p.

  Research output: Contribution to journal › Article › peer-review

  • Lassa virus fever
  • Lassa virus
  • Lassa Fever
  • Arenavirus
  • Western Africa
  33 Scopus citations

• Pathogenesis of the viral hemorrhagic fevers

  Paessler, S. & Walker, D. H., Jan 2013, In: Annual Review of Pathology: Mechanisms of Disease. 8, p. 411-440 30 p.

  Research output: Contribution to journal › Review article › peer-review

  • Viral Hemorrhagic Fevers
  • fever
  • pathogenesis
  • Marburg Virus Disease
  • Orthobunyavirus
  152 Scopus citations

• Recent molecular insights into rickettsial pathogenesis and immunity

  Sahni, S. K., Narra, H. P., Sahni, A. & Walker, D. H., Oct 2013, In: Future Microbiology. 8, 10, p. 1265-1288 24 p.

  Research output: Contribution to journal › Review article › peer-review

  • Arthropods
  • Rickettsia prowazekii
  • Immunity
  • Rickettsia Infections
  • Epidemic Louse-Borne Typhus
  59 Scopus citations

• Recombinant Ehrlichia P29 protein induces a protective immune response in a mouse model of ehrlichiosis

  Thirumalapura, N. R., Crocquet-Valdes, P. A., Saito, T. B., Thomas, S., McBride, J. W. & Walker, D. H., Dec 5 2013, In: Vaccine. 31, 50, p. 5960-5967 8 p.

  Research output: Contribution to journal › Article › peer-review

  • Ehrlichia
  • ehrlichiosis
  • Ehrlichiosis
  • Tandem Repeat Sequences
  • Ehrlichia chaffeensis
  4 Scopus citations

• Review article: Unresolved problems related to scrub typhus: A seriously neglected life-threatening disease

  Paris, D. H., Shelite, T. R., Day, N. P. & Walker, D. H., Aug 2013, In: American Journal of Tropical Medicine and Hygiene. 89, 2, p. 301-307 7 p.

  Research output: Contribution to journal › Review article › peer-review
  133 Scopus citations

• Rocky mountain spotted fever and other rickettsioses

  Walker, D., Jul 8 2013, Schaechter's Mechanisms of Microbial Disease: Fifth Edition. Wolters Kluwer Health Adis (ESP), p. 301-307 7 p.

  Research output: Chapter in Book/Report/Conference proceeding › Chapter

• Simple method to differentiate among Rickettsia species

  Peniche-Lara, G., Zavala-Velazquez, J., Dzul-Rosado, K., Walker, D. H. & Zavala-Castro, J., Apr 1 2013, In: Journal of Molecular Microbiology and Biotechnology. 23, 3, p. 203-208 6 p.

  Research output: Contribution to journal › Article › peer-review

  • Rickettsia
  • Polymerase Chain Reaction
  • Ecosystem
  • Enzymes
  • Restriction Fragment Length Polymorphisms
  8 Scopus citations

• Spotted fever group Rickettsia in small rodents from areas of low endemicity for Brazilian spotted fever in the Eastern Region of Minas Gerais State, Brazil

  Milagres, B. S., Padilha, A. F., Montandon, C. E., Freitas, R. N., Pacheco, R., Walker, D. H., Labruna, M. B., Mafra, C. L. & Galvão, M. A. M., May 2013, In: American Journal of Tropical Medicine and Hygiene. 88, 5, p. 937-939 3 p.

  Research output: Contribution to journal › Article › peer-review

  • Rocky Mountain Spotted Fever
  • Spotted Fever Group Rickettsiosis
  • Rickettsia
  • Brazil
  • Rodentia
  7 Scopus citations
• 2012

  Contribution of NK cells to the innate phase of host protection against an intracellular bacterium targeting systemic endothelium

  Fang, R., Ismail, N. & Walker, D. H., Jul 2012, In: American Journal of Pathology. 181, 1, p. 185-195 11 p.

  Research output: Contribution to journal › Article › peer-review

  • Natural Killer Cells
  • Endothelium
  • Bacteria
  • Rickettsia
  • Interferons
  20 Scopus citations

• Human ehrlichioses and rickettsioses in Cameroon

  Ndip, LN., Ndip, R., Walker, D. H. & McBride, J. W., 2012, Current Topics in Tropical Medicine. p. 25-42

  Research output: Chapter in Book/Report/Conference proceeding › Chapter

• Immune Mediators of protective and pathogenic immune responses in patients with mild and fatal human monocytotropic ehrlichiosis

  Ismail, N., Walker, D. H., Ghose, P. & Tang, Y. W., May 21 2012, In: BMC Immunology. 13, 26.

  Research output: Contribution to journal › Article › peer-review

  • Ehrlichiosis
  • Chemokines
  • Septic Shock
  • Interleukin-1
  • Interleukin-10
  11 Scopus citations

• Letters to the editor

  Walker, D., Mar 2012, In: Archives of Pathology and Laboratory Medicine. 136, 3, p. 235-236 2 p.

  Research output: Contribution to journal › Letter › peer-review

• New insight into immunity and immunopathology of Rickettsial diseases

  Mansueto, P., Vitale, G., Cascio, A., Seidita, A., Pepe, I., Carroccio, A., Di Rosa, S., Rini, G. B., Cillari, E. & Walker, D. H., 2012, In: Clinical and Developmental Immunology. 2012, 967852.

  Research output: Contribution to journal › Review article › peer-review

  • Rickettsia Infections
  • Rickettsia
  • Virulence
  • Immunity
  • Anaplasma
  83 Scopus citations

• Pathogenesis of lassa fever

  Yun, N. E. & Walker, D. H., Oct 2012, In: Viruses. 4, 10, p. 2031-2048 18 p.

  Research output: Contribution to journal › Review article › peer-review

  • Lassa Fever
  • Lassa virus
  • Old World Arenaviruses
  • Arenaviridae
  • Vaccines
  86 Scopus citations

• Person-to-person transmission of severe fever with thrombocytopenia syndrome virus

  Liu, Y., Li, Q., Hu, W., Wu, J., Weng, Y., Mei, L., Walker, D. H., Ren, J., Wang, Y. & Yu, X. J., Feb 1 2012, In: Vector-Borne and Zoonotic Diseases. 12, 2, p. 156-160 5 p.

  Research output: Contribution to journal › Article › peer-review

  • SFTS phlebovirus
  • Thrombocytopenia
  • Fever
  • Viruses
  • Phlebovirus
  154 Scopus citations

• Rickettsia, orientia, ehrlichia, anaplasma and coxiella: Typhus; spotted fevers; scrub typhus; ehrlichioses; Q fever

  Walker, D. & Yu, X. J., Jul 23 2012, Medical Microbiology: Eighteenth Edition. Elsevier Inc., p. 390-399 10 p.

  Research output: Chapter in Book/Report/Conference proceeding › Chapter
  1 Scopus citations

• Rocky mountain spotted fever and other rickettsioses

  Walker, D., May 15 2012, Schaechter's Mechanisms of Microbial Disease: Fifth Edition. Wolters Kluwer Health Adis (ESP), p. 301-307 7 p.

  Research output: Chapter in Book/Report/Conference proceeding › Chapter

• Systemic treatment with cpg-b after sublethal rickettsial infection induces mouse death through indoleamine 2,3-dioxygenase (ido)

  Xin, L., Shelite, T. R., Gong, B., Mendell, N. L., Soong, L., Fang, R. & Walker, D. H., Mar 28 2012, In: PloS one. 7, 3, e34062.

  Research output: Contribution to journal › Article › peer-review

  • indoleamine 2,3-dioxygenase
  • rickettsial diseases
  • T-cells
  • Indoleamine-Pyrrole 2,3,-Dioxygenase
  • Dendritic Cells
  16 Scopus citations