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2020
2020 taxonomic update for phylum Negarnaviricota (Riboviria: Orthornavirae), including the large orders Bunyavirales and Mononegavirales
Kuhn, J. H., Adkins, S., Alioto, D., Alkhovsky, S. V., Amarasinghe, G. K., Anthony, S. J., Avšič-Županc, T., Ayllón, M. A., Bahl, J., Balkema-Buschmann, A., Ballinger, M. J., Bartonička, T., Basler, C., Bavari, S., Beer, M., Bente, D. A., Bergeron, É., Bird, B. H., Blair, C., Blasdell, K. R. & 209 others, , Dec 1 2020, In: Archives of virology. 165, 12, p. 3023-3072 50 p.Research output: Contribution to journal › Article › peer-review
Open Access3 Scopus citations -
Analysis of a Therapeutic Antibody Cocktail Reveals Determinants for Cooperative and Broad Ebolavirus Neutralization
Gilchuk, P., Murin, C. D., Milligan, J. C., Cross, R. W., Mire, C. E., Ilinykh, P. A., Huang, K., Kuzmina, N., Altman, P. X., Hui, S., Gunn, B. M., Bryan, A. L., Davidson, E., Doranz, B. J., Turner, H. L., Alkutkar, T., Flinko, R., Orlandi, C., Carnahan, R., Nargi, R. & 13 others, , Feb 18 2020, In: Immunity. 52, 2, p. 388-403.e12Research output: Contribution to journal › Article › peer-review
Open Access10 Scopus citations -
Annexin a2 depletion exacerbates the intracerebral microhemorrhage induced by acute rickettsia and ebola virus infections
Su, Z., Chang, Q., Drelich, A., Shelite, T., Judy, B., Liu, Y., Xiao, J., Zhou, C., He, X., Jin, Y., Saito, T., Tang, S., Soong, L., Wakamiya, M., Fang, X., Bukreyev, A., Ksiazek, T., Russell, W. K. & Gong, B., Jul 2020, In: PLoS neglected tropical diseases. 14, 7, p. 1-30 30 p., e0007960.Research output: Contribution to journal › Article › peer-review
Open Access -
Ebola virus produces discrete small noncoding RNAs independently of the host MicroRNA pathway which lack RNA interference activity in bat and human cells
Prasad, A. N., Ronk, A. J., Widen, S. G., Wood, T. G., Basler, C. F. & Bukreyev, A., Mar 1 2020, In: Journal of virology. 94, 6, e01441-19.Research output: Contribution to journal › Article › peer-review
3 Scopus citations -
Global phosphoproteomic analysis of Ebola virions reveals a novel role for VP35 phosphorylation-dependent regulation of genome transcription
Ivanov, A., Ramanathan, P., Parry, C., Ilinykh, P. A., Lin, X., Petukhov, M., Obukhov, Y., Ammosova, T., Amarasinghe, G. K., Bukreyev, A. & Nekhai, S., Jul 1 2020, In: Cellular and Molecular Life Sciences. 77, 13, p. 2579-2603 25 p.Research output: Contribution to journal › Article › peer-review
3 Scopus citations -
Modified vaccinia Ankara vaccine expressing Marburg virus-like particles protects guinea pigs from lethal Marburg virus infection
Malherbe, D. C., Domi, A., Hauser, M. J., Meyer, M., Gunn, B. M., Alter, G., Bukreyev, A. & Guirakhoo, F., Dec 1 2020, In: npj Vaccines. 5, 1, 78.Research output: Contribution to journal › Article › peer-review
Open Access -
Non-neutralizing Antibodies from a Marburg Infection Survivor Mediate Protection by Fc-Effector Functions and by Enhancing Efficacy of Other Antibodies
Ilinykh, P. A., Huang, K., Santos, R. I., Gilchuk, P., Gunn, B. M., Karim, M. M., Liang, J., Fouch, M. E., Davidson, E., Parekh, D. V., Kimble, J. B., Pietzsch, C. A., Meyer, M., Kuzmina, N. A., Zeitlin, L., Saphire, E. O., Alter, G., Crowe, J. E. & Bukreyev, A., Jun 10 2020, In: Cell Host and Microbe. 27, 6, p. 976-991.e11Research output: Contribution to journal › Article › peer-review
5 Scopus citations -
Small Molecule Compounds That Inhibit Antioxidant Response Gene Expression in an Inducer-Dependent Manner
Edwards, M. R., Liu, G., De, S., Sourimant, J., Pietzsch, C., Johnson, B., Amarasinghe, G. K., Leung, D. W., Bukreyev, A., Plemper, R. K., Aron, Z., Bowlin, T. L., Moir, D. T. & Basler, C. F., Mar 13 2020, In: ACS Infectious Diseases. 6, 3, p. 489-502 14 p.Research output: Contribution to journal › Article › peer-review
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Species-Specific Evolution of Ebola Virus during Replication in Human and Bat Cells
Whitfield, Z. J., Prasad, A. N., Ronk, A. J., Kuzmin, I. V., Ilinykh, P. A., Andino, R. & Bukreyev, A., Aug 18 2020, In: Cell Reports. 32, 7, 108028.Research output: Contribution to journal › Article › peer-review
Open Access -
Topoisomerase III-β is required for efficient replication of positive-sense RNA viruses
Prasanth, K. R., Hirano, M., Fagg, W. S., McAnarney, E. T., Shan, C., Xie, X., Hage, A., Pietzsch, C. A., Bukreyev, A., Rajsbaum, R., Shi, P. Y., Bedford, M. T., Bradrick, S. S., Menachery, V. & Garcia-Blanco, M. A., Oct 2020, In: Antiviral research. 182, 104874.Research output: Contribution to journal › Article › peer-review
Open Access2 Scopus citations -
2019
Antibody-mediated protective mechanisms induced by a trivalent parainfluenza virus-vectored ebolavirus vaccine
Brian Kimble, J., Malherbe, D. C., Meyer, M., Gunn, B. M., Karim, M. M., Ilinykh, P. A., Iampietro, M., Mohamed, K. S., Negi, S., Gilchuk, P., Huang, K., Wolf, Y. I., Braun, W., Crowe, J. E., Alter, G. & Bukreyev, A., Feb 1 2019, In: Journal of virology. 93, 4, e0184518.Research output: Contribution to journal › Article › peer-review
1 Scopus citations -
Can Ebola Virus Vaccines Have Universal Immune Correlates of protection?
Meyer, M., Malherbe, D. C. & Bukreyev, A., Jan 2019, In: Trends in Microbiology. 27, 1, p. 8-16 9 p.Research output: Contribution to journal › Review article › peer-review
7 Scopus citations -
Cross-reactive neutralizing human survivor monoclonal antibody BDBV223 targets the ebolavirus stalk
King, L. B., West, B. R., Moyer, C. L., Gilchuk, P., Flyak, A., Ilinykh, P. A., Bombardi, R., Hui, S., Huang, K., Bukreyev, A., Crowe, J. E. & Saphire, E. O., Dec 1 2019, In: Nature communications. 10, 1, 1788.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations -
Ebola virus-mediated T-lymphocyte depletion is the result of an abortive infection
Younan, P., Santos, R. I., Ramanathan, P., Iampietro, M., Nishida, A., Dutta, M., Ammosova, T., Meyer, M., Katze, M. G., Popov, V. L., Nekhai, S. & Bukreyev, A., 2019, In: PLoS pathogens. 15, 10, e1008068.Research output: Contribution to journal › Article › peer-review
Open Access5 Scopus citations -
ICTV virus taxonomy profile: Filoviridae
ICTV Report Consortium, Jun 2019, In: Journal of General Virology. 100, 6, p. 911-912 2 p.Research output: Contribution to journal › Article › peer-review
11 Scopus citations -
Structural basis of broad ebolavirus neutralization by a human survivor antibody
West, B. R., Wec, A. Z., Moyer, C. L., Fusco, M. L., Ilinykh, P. A., Huang, K., Wirchnianski, A. S., James, R. M., Herbert, A. S., Hui, S., Goodwin, E., Howell, K. A., Kailasan, S., Aman, M. J., Walker, L. M., Dye, J. M., Bukreyev, A., Chandran, K. & Saphire, E. O., Mar 1 2019, In: Nature Structural and Molecular Biology. 26, 3, p. 204-212 9 p.Research output: Contribution to journal › Article › peer-review
7 Scopus citations -
Targeting the Non-catalytic RVxF Site of Protein Phosphatase-1 With Small Molecules for Ebola Virus Inhibition
Lin, X., Ammosova, T., Choy, M. S., Pietzsch, C. A., Ivanov, A., Ahmad, A., Saygideğer, Y., Kumari, N., Kovalskyy, D., Üren, A., Peti, W., Bukreyev, A. & Nekhai, S., Sep 13 2019, In: Frontiers in Microbiology. 10, 2145.Research output: Contribution to journal › Article › peer-review
Open Access2 Scopus citations -
Taxonomy of the order Mononegavirales: second update 2018
Maes, P., Amarasinghe, G. K., Ayllón, M. A., Basler, C. F., Bavari, S., Blasdell, K. R., Briese, T., Brown, P. A., Bukreyev, A., Balkema-Buschmann, A., Buchholz, U. J., Chandran, K., Crozier, I., de Swart, R. L., Dietzgen, R. G., Dolnik, O., Domier, L. L., Drexler, J. F., Dürrwald, R., Dundon, W. G. & 57 others, , Apr 3 2019, In: Archives of virology. 164, 4, p. 1233-1244 12 p.Research output: Contribution to journal › Article › peer-review
Open Access35 Scopus citations -
Taxonomy of the order Mononegavirales: update 2019
Amarasinghe, G. K., Ayllón, M. A., Bào, Y., Basler, C. F., Bavari, S., Blasdell, K. R., Briese, T., Brown, P. A., Bukreyev, A., Balkema-Buschmann, A., Buchholz, U. J., Chabi-Jesus, C., Chandran, K., Chiapponi, C., Crozier, I., de Swart, R. L., Dietzgen, R. G., Dolnik, O., Drexler, J. F., Dürrwald, R. & 64 others, , Jul 1 2019, In: Archives of virology. 164, 7, p. 1967-1980 14 p.Research output: Contribution to journal › Article › peer-review
Open Access65 Scopus citations -
2017
A Sensitive in Vitro High-Throughput Screen to Identify Pan-filoviral Replication Inhibitors Targeting the VP35-NP Interface
Liu, G., Nash, P. J., Johnson, B., Pietzsch, C., Ilagan, M. X. G., Bukreyev, A., Basler, C. F., Bowlin, T. L., Moir, D. T., Leung, D. W. & Amarasinghe, G. K., Mar 10 2017, In: ACS Infectious Diseases. 3, 3, p. 190-198 9 p.Research output: Contribution to journal › Article › peer-review
11 Scopus citations -
Ebola virus binding to Tim-1 on T lymphocytes induces a cytokine storm
Younan, P., Iampietro, M., Nishida, A., Ramanathan, P., Santos, R. I., Dutta, M., Lubaki, N. M., Koup, R. A., Katze, M. G. & Bukreyev, A., Sep 1 2017, In: mBio. 8, 5, e00845-17.Research output: Contribution to journal › Article › peer-review
38 Scopus citations -
Ebola virus glycoprotein directly triggers T lymphocyte death despite of the lack of infection
Iampietro, M., Younan, P., Nishida, A., Dutta, M., Lubaki, N. M., Santos, R. I., Koup, R. A., Katze, M. G. & Bukreyev, A., May 2017, In: PLoS pathogens. 13, 5, e1006397.Research output: Contribution to journal › Article › peer-review
25 Scopus citations -
Implementation of objective PASC-derived taxon demarcation criteria for official classification of filoviruses
Bào, Y., Amarasinghe, G. K., Basler, C. F., Bavari, S., Bukreyev, A., Chandran, K., Dolnik, O., Dye, J. M., Ebihara, H., Formenty, P., Hewson, R., Kobinger, G. P., Leroy, E. M., Mühlberger, E., Netesov, S. V., Patterson, J. L., Paweska, J. T., Smither, S. J., Takada, A., Towner, J. S. & 3 others, , May 11 2017, In: Viruses. 9, 5, 106.Research output: Contribution to journal › Letter › peer-review
9 Scopus citations -
Innate immune responses of bat and human cells to filoviruses: Commonalities and distinctions
Kuzmin, I. V., Schwarz, T. M., Ilinykh, P. A., Jordan, I., Ksiazek, T. G., Sachidanandam, R., Basler, C. F. & Bukreyev, A., Apr 1 2017, In: Journal of virology. 91, 8, e02471-16.Research output: Contribution to journal › Article › peer-review
25 Scopus citations -
Possibility and challenges of conversion of current virus species names to Linnaean binomials
Postler, T. S., Clawson, A. N., Amarasinghe, G. K., Basler, C. F., Bavari, S., Benko, M., Blasdell, K. R., Briese, T., Buchmeier, M. J., Bukreyev, A., Calisher, C. H., Chandran, K., Charrel, R., Clegg, C. S., Collins, P. L., De La Torre, J. C., DeRisi, J. L., Dietzgen, R. G., Dolnik, O., Dürrwald, R. & 52 others, , May 1 2017, In: Systematic Biology. 66, 3, p. 463-473 11 p.Research output: Contribution to journal › Article › peer-review
11 Scopus citations -
Taxonomy of the order Mononegavirales: update 2017
Amarasinghe, G. K., Bào, Y., Basler, C. F., Bavari, S., Beer, M., Bejerman, N., Blasdell, K. R., Bochnowski, A., Briese, T., Bukreyev, A., Calisher, C. H., Chandran, K., Collins, P. L., Dietzgen, R. G., Dolnik, O., Dürrwald, R., Dye, J. M., Easton, A. J., Ebihara, H., Fang, Q. & 53 others, , Aug 1 2017, In: Archives of virology. 162, 8, p. 2493-2504 12 p.Research output: Contribution to journal › Article › peer-review
134 Scopus citations -
Topoisomerase II inhibitors induce DNA damage-dependent interferon responses circumventing ebola virus immune evasion
Luthra, P., Aguirre, S., Yen, B. C., Pietzsch, C. A., Sanchez-Aparicio, M. T., Tigabu, B., Morlock, L. K., García-Sastre, A., Leung, D. W., Williams, N. S., Fernandez-Sesma, A., Bukreyev, A. & Basler, C. F., Mar 1 2017, In: mBio. 8, 2, e00368-17.Research output: Contribution to journal › Article › peer-review
36 Scopus citations -
2015
Adapting high-throughput screening methods and assays for biocontainment laboratories
Rasmussen, L., Tigabu, B., White, E. L., Bostwick, R., Tower, N., Bukreyev, A., Rockx, B., Leduc, J. W. & Noah, J. W., Feb 1 2015, In: Assay and Drug Development Technologies. 13, 1, p. 44-54 11 p.Research output: Contribution to journal › Article › peer-review
5 Scopus citations -
Aerosolized Ebola vaccine protects primates and elicits lung-resident T cell responses
Meyer, M., Garron, T., Lubaki, N. M., Mire, C. E., Fenton, K. A., Klages, C., Olinger, G. G., Geisbert, T. W., Collins, P. L. & Bukreyev, A., Aug 3 2015, In: Journal of Clinical Investigation. 125, 8, p. 3241-3255 15 p.Research output: Contribution to journal › Article › peer-review
45 Scopus citations -
Different temporal effects of Ebola virus VP35 and VP24 proteins on global gene expression in human dendritic cells
Ilinykh, P. A., Lubaki, N. M., Widen, S. G., Renn, L. A., Theisen, T. C., Rabin, R. L., Wood, T. G. & Bukreyev, A., 2015, In: Journal of virology. 89, 15, p. 7567-7583 17 p.Research output: Contribution to journal › Article › peer-review
32 Scopus citations -
Mechanism of Human Antibody-Mediated Neutralization of Marburg Virus
Flyak, A. I., Ilinykh, P. A., Murin, C. D., Garron, T., Shen, X., Fusco, M. L., Hashiguchi, T., Bornholdt, Z. A., Slaughter, J. C., Sapparapu, G., Klages, C., Ksiazek, T. G., Ward, A. B., Saphire, E. O., Bukreyev, A. & Crowe, J. E., Feb 26 2015, In: Cell. 160, 5, p. 893-903 11 p.Research output: Contribution to journal › Article › peer-review
83 Scopus citations -
Partial attenuation of respiratory syncytial virus with a deletion of a small hydrophobic gene is associated with elevated interleukin-1β responses
Russell, R. F., McDonald, J. U., Ivanova, M., Zhong, Z., Bukreyev, A. & Tregoning, J. S., 2015, In: Journal of virology. 89, 17, p. 8974-8981 8 p.Research output: Contribution to journal › Article › peer-review
33 Scopus citations -
2014
A BSL-4 high-throughput screen identifies sulfonamide inhibitors of Nipah virus
Tigabu, B., Rasmussen, L., White, E. L., Tower, N., Saeed, M., Bukreyev, A., Rockx, B., Leduc, J. W. & Noah, J. W., Apr 1 2014, In: Assay and Drug Development Technologies. 12, 3, p. 155-161 7 p.Research output: Contribution to journal › Article › peer-review
11 Scopus citations -
A comprehensive proteomic view of responses of A549 type II alveolar epithelial cells to human respiratory syncytial virus infection
Dave, K. A., Norris, E. L., Bukreyev, A. A., Headlam, M. J., Buchholz, U. J., Singh, T., Collins, P. L. & Gorman, J. J., Dec 1 2014, In: Molecular and Cellular Proteomics. 13, 12, p. 3250-3269 20 p.Research output: Contribution to journal › Article › peer-review
22 Scopus citations -
Discussions and decisions of the 2012-2014 International Committee on Taxonomy of Viruses (ICTV) Filoviridae Study Group, January 2012-June 2013
Bukreyev, A. A., Chandran, K., Dolnik, O., Dye, J. M., Ebihara, H., Leroy, E. M., Mühlberger, E., Netesov, S. V., Patterson, J. L., Paweska, J. T., Saphire, E. O., Smither, S. J., Takada, A., Towner, J. S., Volchkov, V. E., Warren, T. K. & Kuhn, J. H., Apr 2014, In: Archives of virology. 159, 4, p. 821-830 10 p.Research output: Contribution to journal › Article › peer-review
66 Scopus citations -
Filovirus refseq entries: Evaluation and selection of filovirus type variants, Type sequences, And names
Kuhn, J. H., Andersen, K. G., Bào, Y., Bavari, S., Becker, S., Bennett, R. S., Bergman, N. H., Blinkova, O., Bradfute, S., Rodney Brister, J., Bukreyev, A., Chandran, K., Chepurnov, A. A., Davey, R. A., Dietzgen, R. G., Doggett, N. A., Dolnik, O., Dye, J. M., Enterlein, S., Fenimore, P. W. & 56 others, , 2014, In: Viruses. 6, 9, p. 3663-3682 20 p.Research output: Contribution to journal › Letter › peer-review
40 Scopus citations -
Role of protein phosphatase 1 in dephosphorylation of Ebola virus VP30 protein and its targeting for the inhibition of viral transcription
Ilinykh, P. A., Tigabu, B., Ivanov, A., Ammosova, T., Obukhov, Y., Garron, T., Kumari, N., Kovalskyy, D., Platonov, M. O., Naumchik, V. S., Freiberg, A. N., Nekhai, S. & Bukreyev, A., Aug 15 2014, In: Journal of Biological Chemistry. 289, 33, p. 22723-22738 16 p.Research output: Contribution to journal › Article › peer-review
51 Scopus citations -
Virus nomenclature below the species level: A standardized nomenclature for filovirus strains and variants rescued from cDNA
Kuhn, J. H., Bào, Y., Bavari, S., Becker, S., Bradfute, S., Brauburger, K., Rodney Brister, J., Bukreyev, A. A., Caì, Y., Chandran, K., Davey, R. A., Dolnik, O., Dye, J. M., Enterlein, S., Gonzalez, J. P., Formenty, P., Freiberg, A. N., Hensley, L. E., Hoenen, T., Honko, A. N. & 32 others, , May 2014, In: Archives of virology. 159, 5, p. 1229-1237 9 p.Research output: Contribution to journal › Article › peer-review
53 Scopus citations -
2013
Neonatal antibody responses are attenuated by interferon-γ produced by NK and T cells during RSV infection
Tregoning, J. S., Wang, B. L., McDonald, J. U., Yamaguchi, Y., Harker, J. A., Goritzka, M., Johansson, C., Bukreyev, A., Collins, P. L. & Openshaw, P. J., Apr 2 2013, In: Proceedings of the National Academy of Sciences of the United States of America. 110, 14, p. 5576-5581 6 p.Research output: Contribution to journal › Article › peer-review
25 Scopus citations -
The Lack of Maturation of Ebola Virus-Infected Dendritic Cells Results from the Cooperative Effect of at Least Two Viral Domains
Lubaki, N. M., Ilinykh, P., Pietzsch, C., Tigabu, B., Freiberg, A. N., Koup, R. A. & Bukreyev, A., 2013, In: Journal of virology. 87, 22, p. 12506 1 p.Research output: Contribution to journal › Comment/debate › peer-review
6 Scopus citations -
Virus nomenclature below the species level: A standardized nomenclature for natural variants of viruses assigned to the family Filoviridae
Kuhn, J. H., Bao, Y., Bavari, S., Becker, S., Bradfute, S., Brister, J. R., Bukreyev, A. A., Chandran, K., Davey, R. A., Dolnik, O., Dye, J. M., Enterlein, S., Hensley, L. E., Honko, A. N., Jahrling, P. B., Johnson, K. M., Kobinger, G., Leroy, E. M., Lever, M. S., Mühlberger, E. & 17 others, , 2013, In: Archives of virology. 158, 1, p. 301-311 11 p.Research output: Contribution to journal › Article › peer-review
71 Scopus citations -
Virus nomenclature below the species level: A standardized nomenclature for laboratory animal-adapted strains and variants of viruses assigned to the family Filoviridae
Kuhn, J. H., Bao, Y., Bavari, S., Becker, S., Bradfute, S., Brister, J. R., Bukreyev, A. A., Caì, Y., Chandran, K., Davey, R. A., Dolnik, O., Dye, J. M., Enterlein, S., Gonzalez, J. P., Formenty, P., Freiberg, A. N., Hensley, L. E., Honko, A. N., Ignatyev, G. M., Jahrling, P. B. & 30 others, , Jun 2013, In: Archives of virology. 158, 6, p. 1425-1432 8 p.Research output: Contribution to journal › Article › peer-review
39 Scopus citations -
2012
The human respiratory syncytial virus nonstructural protein 1 regulates type I and type II interferon pathways
Hastie, M. L., Headlam, M. J., Patel, N. B., Bukreyev, A. A., Buchholz, U. J., Dave, K. A., Norris, E. L., Wright, C. L., Spann, K. M., Collins, P. L. & Gorman, J. J., May 2012, In: Molecular and Cellular Proteomics. 11, 5, p. 108-127 20 p.Research output: Contribution to journal › Article › peer-review
38 Scopus citations -
The secreted g protein of human respiratory syncytial virus antagonizes antibody-mediated restriction of replication involving macrophages and complement
Bukreyev, A., Yang, L. & Collins, P. L., Oct 2012, In: Journal of virology. 86, 19, p. 10880-10884 5 p.Research output: Contribution to journal › Article › peer-review
26 Scopus citations