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• 2020

  Enzymatically inactive OGG1 binds to DNA and steers base excision repair toward gene transcription

  Hao, W., Wang, J., Zhang, Y., Wang, C., Xia, L., Zhang, W., Zafar, M., Kang, J. Y., Wang, R., Ali Bohio, A., Pan, L., Zeng, X., Wei, M., Boldogh, I. & Ba, X., Jun 1 2020, In: FASEB Journal. 34, 6, p. 7427-7441 15 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • 8-hydroxyguanine
  • Transcription
  • DNA Repair
  • Genes
  • Repair
  1 Scopus citations

• Exercise, redox system and neurodegenerative diseases

  Quan, H., Koltai, E., Suzuki, K., Aguiar, A. S., Pinho, R., Boldogh, I., Berkes, I. & Radak, Z., Oct 1 2020, In: Biochimica et Biophysica Acta - Molecular Basis of Disease. 1866, 10, 165778.

  Research output: Contribution to journal › Review article › peer-review

  Open Access

  • Oxidation-Reduction
  • Neurodegenerative Diseases
  • Reactive Oxygen Species
  • Housekeeping
  • Brain-Derived Neurotrophic Factor

• Pervasive Genomic Damage in Experimental Intracerebral Hemorrhage: Therapeutic Potential of a Mechanistic-Based Carbon Nanoparticle

  Dharmalingam, P., Talakatta, G., Mitra, J., Wang, H., Derry, P. J., Nilewski, L. G., McHugh, E. A., Fabian, R. H., Mendoza, K., Vasquez, V., Hegde, P. M., Kakadiaris, E., Roy, T., Boldogh, I., Hegde, V. L., Mitra, S., Tour, J. M., Kent, T. A. & Hegde, M. L., Mar 24 2020, In: ACS Nano. 14, 3, p. 2827-2846 20 p.

  Research output: Contribution to journal › Article › peer-review

  • hemorrhages
  • Hemin
  • Nanoparticles
  • Carbon
  • Iron
  4 Scopus citations

• Poly(ADP-ribosyl)ation enhances HuR oligomerization and contributes to pro-inflammatory gene mRNA stabilization

  Ke, Y., Lv, X., Fu, X., Zhang, J., Bohio, A. A., Zeng, X., Hao, W., Wang, R., Boldogh, I. & Ba, X., 2020, (Accepted/In press) In: Cellular and Molecular Life Sciences.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Poly ADP Ribosylation
  • Poly (ADP-Ribose) Polymerase-1
  • Messenger RNA
  • Genes
  • MicroRNAs

• The systemic role of SIRT1 in exercise mediated adaptation

  Radak, Z., Suzuki, K., Posa, A., Petrovszky, Z., Koltai, E. & Boldogh, I., Aug 2020, In: Redox Biology. 35, 101467.

  Research output: Contribution to journal › Review article › peer-review

  Open Access

  • Muscle
  • Neurodegenerative diseases
  • Exercise
  • Liver
  • NAD
  2 Scopus citations
• 2019

  C-Abl-mediated tyrosine phosphorylation of PARP1 is crucial for expression of proinflammatory genes

  Bohio, A. A., Sattout, A., Wang, R., Wang, K., Sah, R. K., Guo, X., Zeng, X., Ke, Y., Boldogh, I. & Ba, X., Sep 15 2019, In: Journal of Immunology. 203, 6, p. 1521-1531 11 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Poly (ADP-Ribose) Polymerase-1
  • Tyrosine
  • Phosphorylation
  • Gene Expression
  • Poly ADP Ribosylation
  5 Scopus citations

• Epigenetic regulation of TIMP1 expression by 8-oxoguanine DNA glycosylase-1 binding to DNA:RNA hybrid

  Pan, L., Wang, H., Luo, J., Zeng, J., Pi, J., Liu, H., Liu, C., Ba, X., Qu, X., Xiang, Y., Boldogh, I. & Qin, X., Dec 1 2019, In: FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 33, 12, p. 14159-14170 12 p.

  Research output: Contribution to journal › Article › peer-review

  • 8-hydroxyguanine
  • DNA Glycosylases
  • Tissue Inhibitor of Metalloproteinase-1
  • Epigenomics
  • RNA

• Exercise and probiotics attenuate the development of Alzheimer's disease in transgenic mice: Role of microbiome

  Abraham, D., Feher, J., Scuderi, G. L., Szabo, D., Dobolyi, A., Cservenak, M., Juhasz, J., Ligeti, B., Pongor, S., Gomez-Cabrera, M. C., Vina, J., Higuchi, M., Suzuki, K., Boldogh, I. & Radak, Z., Jan 2019, In: Experimental Gerontology. 115, p. 122-131 10 p.

  Research output: Contribution to journal › Article › peer-review

  • Probiotics
  • Microbiota
  • Transgenic Mice
  • Alzheimer Disease
  • Amyloid
  30 Scopus citations

• Exercise effects on physiological function during aging

  Radak, Z., Torma, F., Berkes, I., Goto, S., Mimura, T., Posa, A., Balogh, L., Boldogh, I., Suzuki, K., Higuchi, M. & Koltai, E., Feb 20 2019, In: Free Radical Biology and Medicine. 132, p. 33-41 9 p.

  Research output: Contribution to journal › Review article › peer-review

  • Protease La
  • Aging of materials
  • Mitochondrial Degradation
  • Housekeeping
  • Exercise
  22 Scopus citations

• Motor neuron disease-associated loss of nuclear TDP-43 is linked to DNA double-strand break repair defects

  Mitra, J., Guerrero, E. N., Hegde, P. M., Liachko, N. F., Wang, H., Vasquez, V., Gao, J., Pandey, A., Paul Taylor, J., Kraemer, B. C., Wu, P., Boldogh, I., Garruto, R. M., Mitra, S., Rao, K. S. & Hegde, M. L., 2019, In: Proceedings of the National Academy of Sciences of the United States of America. 116, 10, p. 4696-4705 10 p.

  Research output: Contribution to journal › Article › peer-review

  • Motor Neuron Disease
  • Double-Stranded DNA Breaks
  • DNA Damage
  • Amyotrophic lateral sclerosis 1
  • DNA-Binding Proteins
  43 Scopus citations

• Oxidized base 8-oxoguanine, a product of DNA repair processes, contributes to dendritic cell activation

  Pázmándi, K., Sütő, M., Fekete, T., Varga, A., Boldizsár, E., Boldogh, I. & Bácsi, A., Nov 1 2019, In: Free Radical Biology and Medicine. 143, p. 209-220 12 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Dendritic Cells
  • 8-hydroxyguanine
  • DNA Glycosylases
  • DNA Repair
  • Chemical activation
  3 Scopus citations

• Roles of DNA repair enzyme OGG1 in innate immunity and its significance for lung cancer

  Vlahopoulos, S., Adamaki, M., Khoury, N., Zoumpourlis, V. & Boldogh, I., Feb 2019, In: Pharmacology and Therapeutics. 194, p. 59-72 14 p.

  Research output: Contribution to journal › Review article › peer-review

  • DNA Repair Enzymes
  • Oxidants
  • Innate Immunity
  • Lung Neoplasms
  • Cytokines
  12 Scopus citations

• Targeting inducible epigenetic reprogramming pathways in chronic airway remodeling

  Brasier, A. R. & Boldogh, I., 2019, In: Drugs in Context. 8, 2019-8-3.

  Research output: Contribution to journal › Review article › peer-review

  Open Access

  • Airway Remodeling
  • Epigenomics
  • Toll-Like Receptors
  • Inflammation
  • 8-hydroxyguanine
• 2018

  Effects of the stimuli-dependent enrichment of 8-oxoguanine DNA glycosylase1 on chromatinized DNA

  Hao, W., Qi, T., Pan, L., Wang, R., Zhu, B., Aguilera-Aguirre, L., Radak, Z., Hazra, T. K., Vlahopoulos, S. A., Bacsi, A., Brasier, A. R., Ba, X. & Boldogh, I., Sep 2018, In: Redox Biology. 18, p. 43-53 11 p.

  Research output: Contribution to journal › Article › peer-review

  • 8-hydroxyguanine
  • DNA Glycosylases
  • DNA
  • Genes
  • Gene Expression
  14 Scopus citations

• Excision release of 5?hydroxycytosine oxidatively induced DNA base lesions from the lung genome by cat dander extract challenge stimulates allergic airway inflammation

  Hosoki, K., Jaruga, P., Itazawa, T., Aguilera-Aguirre, L., Coskun, E., Hazra, T. K., Boldogh, I., Dizdaroglu, M. & Sur, S., Dec 2018, In: Clinical and Experimental Allergy. 48, 12, p. 1676-1687 12 p.

  Research output: Contribution to journal › Article › peer-review

  • Dander
  • Cats
  • hydroxide ion
  • Genome
  • Inflammation
  1 Scopus citations

• Master athletes have higher miR-7, SIRT3 and SOD2 expression in skeletal muscle than age-matched sedentary controls

  Koltai, E., Bori, Z., Osvath, P., Ihasz, F., Peter, S., Toth, G., Degens, H., Rittweger, J., Boldogh, I. & Radak, Z., Oct 2018, In: Redox Biology. 19, p. 46-51 6 p.

  Research output: Contribution to journal › Article › peer-review

  • Muscle
  • Athletes
  • Skeletal Muscle
  • Muscles
  • Quadriceps Muscle
  14 Scopus citations

• OGG1-initiated base excision repair exacerbates oxidative stress-induced parthanatos

  Wang, R., Li, C., Qiao, P., Xue, Y., Zheng, X., Chen, H., Zeng, X., Liu, W., Boldogh, I. & Ba, X., Jun 1 2018, In: Cell Death and Disease. 9, 6, 628.

  Research output: Contribution to journal › Article › peer-review

  • Poly (ADP-Ribose) Polymerase-1
  • DNA Repair
  • Cell Death
  • Oxidative Stress
  • 8-hydroxyguanine
  17 Scopus citations

• Small-molecule inhibitor of OGG1 suppresses proinflammatory gene expression and inflammation

  Visnes, T., Cázares-Körner, A., Hao, W., Wallner, O., Masuyer, G., Loseva, O., Mortusewicz, O., Wiita, E., Sarno, A., Manoilov, A., Astorga-Wells, J., Jemth, A. S., Pan, L., Sanjiv, K., Karsten, S., Gokturk, C., Grube, M., Homan, E. J., Hanna, B. M. F., Paulin, C. B. J. & 20 others, Pham, T., Rasti, A., Berglund, U. W., Von Nicolai, C., Benitez-Buelga, C., Koolmeister, T., Ivanic, D., Iliev, P., Scobie, M., Krokan, H. E., Baranczewski, P., Artursson, P., Altun, M., Jensen, A. J., Kalderén, C., Ba, X., Zubarev, R. A., Stenmark, P., Boldogh, I. & Helleday, T., Nov 16 2018, In: Science. 362, 6416, p. 834-839 6 p.

  Research output: Contribution to journal › Article › peer-review

  • DNA Glycosylases
  • Gene Expression
  • Inflammation
  • 7,8-dihydro-8-oxoguanine
  • DNA
  36 Scopus citations

• The establishment of methods for free PAR generation and PAR reader detection

  Ke, Y., Wang, K., Xu, H., Wang, C., Zhang, J., Zeng, X., Wang, R., Boldogh, I. & Ba, X., Jan 1 2018, (Accepted/In press) In: Molecular and Cellular Probes.

  Research output: Contribution to journal › Article › peer-review

  • Poly (ADP-Ribose) Polymerase-1
  • Proteins
  • 1,2-di-(4-sulfamidophenyl)-4-butylpyrazolidine-3,5-dione
  • Poly Adenosine Diphosphate Ribose
  • NAD
  1 Scopus citations

• The roles of base excision repair enzyme OGG1 in gene expression

  Wang, R., Hao, W., Pan, L., Boldogh, I. & Ba, X., Oct 1 2018, In: Cellular and Molecular Life Sciences. 75, 20, p. 3741-3750 10 p.

  Research output: Contribution to journal › Review article › peer-review

  • 8-hydroxyguanine
  • DNA Repair
  • Gene Expression
  • DNA
  • Enzymes
  19 Scopus citations
• 2016

  Facilitation of allergic sensitization and allergic airway inflammation by pollen-induced innate neutrophil recruitment

  Hosoki, K., Aguilera-Aguirre, L., Brasier, A. R., Kurosky, A., Boldogh, I. & Sur, S., Jan 2016, In: American journal of respiratory cell and molecular biology. 54, 1, p. 81-90 10 p.

  Research output: Contribution to journal › Article › peer-review

  • Pollen
  • Neutrophil Infiltration
  • ragweed pollen
  • Inflammation
  • Toll-Like Receptor 4
  20 Scopus citations

• Inside-Out Signaling Pathways from Nuclear Reactive Oxygen Species Control Pulmonary Innate Immunity

  Choudhary, S., Boldogh, I. & Brasier, A. R., Mar 1 2016, In: Journal of Innate Immunity. 8, 2, p. 143-155 13 p.

  Research output: Contribution to journal › Review article › peer-review

  • Innate Immunity
  • Reactive Oxygen Species
  • Ataxia Telangiectasia
  • Lung
  • 8-hydroxyguanine
  23 Scopus citations

• Myeloid differentiation protein 2 facilitates pollen- and cat dander-induced innate and allergic airway inflammation

  Hosoki, K., Boldogh, I., Aguilera-Aguirre, L., Sun, Q., Itazawa, T., Hazra, T., Brasier, A. R., Kurosky, A. & Sur, S., May 1 2016, In: Journal of Allergy and Clinical Immunology. 137, 5, p. 1506-1513.e2

  Research output: Contribution to journal › Article › peer-review

  • Dander
  • Pollen
  • ragweed pollen
  • Cats
  • Inflammation
  12 Scopus citations

• Neutrophil recruitment by allergens contribute to allergic sensitization and allergic inflammation

  Hosoki, K., Itazawa, T., Boldogh, I. & Sur, S., 2016, In: Current opinion in allergy and clinical immunology. 16, 1, p. 45-50 6 p.

  Research output: Contribution to journal › Review article › peer-review

  • Neutrophil Infiltration
  • Allergens
  • Neutrophils
  • Dander
  • Inflammation
  38 Scopus citations

• Oxidized guanine base lesions function in 8-oxoguanine DNA glycosylase-1-mediated epigenetic regulation of nuclear factor κB-driven gene expression

  Pan, L., Zhu, B., Hao, W., Zeng, X., Vlahopoulos, S. A., Hazra, T. K., Hegde, M. L., Radak, Z., Bacsi, A., Brasier, A. R., Ba, X. & Boldogh, I., Dec 2 2016, In: Journal of Biological Chemistry. 291, 49, p. 25553-25566 14 p.

  Research output: Contribution to journal › Article › peer-review

  • 8-hydroxyguanine
  • DNA Glycosylases
  • Guanine
  • Gene expression
  • DNA Repair
  74 Scopus citations

• Pathophysiology of bronchoconstriction: Role of oxidatively damaged DNA repair

  Bacsi, A., Pan, L., Ba, X. & Boldogh, I., 2016, In: Current opinion in allergy and clinical immunology. 16, 1, p. 59-67 9 p.

  Research output: Contribution to journal › Review article › peer-review

  • Bronchoconstriction
  • 8-hydroxyguanine
  • DNA Repair
  • DNA
  • Smooth Muscle
  11 Scopus citations

• Physical exercise, reactive oxygen species and neuroprotection

  Radak, Z., Suzuki, K., Higuchi, M., Balogh, L., Boldogh, I. & Koltai, E., Sep 1 2016, In: Free Radical Biology and Medicine. 98, p. 187-196 10 p.

  Research output: Contribution to journal › Article › peer-review

  • Neuroprotection
  • Reactive Oxygen Species
  • Exercise
  • Oxidation-Reduction
  • Brain
  54 Scopus citations

• The Potential Role of 8-Oxoguanine DNA Glycosylase-Driven DNA Base Excision Repair in Exercise-Induced Asthma

  Belanger, K. A. K., Ameredes, B. T., Boldogh, I. & Aguilera-Aguirre, L., 2016, In: Mediators of inflammation. 2016, 3762561.

  Research output: Contribution to journal › Review article › peer-review

  • 8-hydroxyguanine
  • DNA Glycosylases
  • Exercise-Induced Asthma
  • DNA Repair
  • DNA
  5 Scopus citations

• The rate of training response to aerobic exercise affects brain function of rats

  Marton, O., Koltai, E., Takeda, M., Mimura, T., Pajk, M., Abraham, D., Koch, L. G., Britton, S. L., Higuchi, M., Boldogh, I. & Radak, Z., Oct 1 2016, In: Neurochemistry International. 99, p. 16-23 8 p.

  Research output: Contribution to journal › Article › peer-review

  • Exercise
  • Running
  • Brain
  • Protein Carbonylation
  • Cyclic AMP Response Element-Binding Protein
  6 Scopus citations
• 2014

  8-Oxoguanine DNA glycosylase-1 augments proinflammatory gene expression by facilitating the recruitment of site-specific transcription factors

  Ba, X., Bacsi, A., Luo, J., Aguilera-Aguirre, L., Zeng, X., Radak, Z., Brasier, A. R. & Boldogh, I., Mar 1 2014, In: Journal of Immunology. 192, 5, p. 2384-2394 11 p.

  Research output: Contribution to journal › Article › peer-review

  • 8-hydroxyguanine
  • DNA Glycosylases
  • Transcription Factors
  • Gene Expression
  • Guanine
  54 Scopus citations

• 8-Oxoguanine DNA glycosylase-1-mediated DNA repair is associated with Rho GTPase activation and α-smooth muscle actin polymerization

  Luo, J., Hosoki, K., Bacsi, A., Radak, Z., Hegde, M. L., Sur, S., Hazra, T. K., Brasier, A. R., Ba, X. & Boldogh, I., Aug 2014, In: Free Radical Biology and Medicine. 73, p. 430-438 9 p.

  Research output: Contribution to journal › Article › peer-review

  • 8-hydroxyguanine
  • DNA Glycosylases
  • rho GTP-Binding Proteins
  • Polymerization
  • Muscle
  36 Scopus citations

• ATM regulates NF-κB-dependent immediate-early genes via RelA ser 276 phosphorylation coupled to CDK9 promoter recruitment

  Fang, L., Choudhary, S., Zhao, Y., Edeh, C. B., Yang, C., Boldogh, I. & Brasier, A. R., 2014, In: Nucleic acids research. 42, 13, p. 8416-8432 17 p.

  Research output: Contribution to journal › Article › peer-review

  • Ataxia Telangiectasia
  • Immediate-Early Genes
  • Phosphorylation
  • Cyclin-Dependent Kinase 9
  • Double-Stranded DNA Breaks
  32 Scopus citations

• Eating habits modulate short term memory and epigenetical regulation of brain derived neurotrophic factor in hippocampus of low- and high running capacity rats

  Torma, F., Bori, Z., Koltai, E., Felszeghy, K., Vacz, G., Koch, L., Britton, S., Boldogh, I. & Radak, Z., Aug 2014, In: Brain Research Bulletin. 107, p. 54-60 7 p.

  Research output: Contribution to journal › Article › peer-review

  • Brain-Derived Neurotrophic Factor
  • Feeding Behavior
  • Short-Term Memory
  • Hippocampus
  • Organelle Biogenesis
  2 Scopus citations

• Effects of diabetes on oxidative and nitrosative stress in kidney mitochondria from aged rats

  Pérez-Gallardo, R. V., Noriega-Cisneros, R., Esquivel-Gutiérrez, E., Calderón-Cortés, E., Cortés-Rojo, C., Manzo-Avalos, S., Campos-García, J., Salgado-Garciglia, R., Montoya-Pérez, R., Boldogh, I. & Saavedra-Molina, A., Dec 9 2014, In: Journal of Bioenergetics and Biomembranes. 46, 6, p. 511-518 8 p.

  Research output: Contribution to journal › Article › peer-review

  • Nitrosative Stress
  • Mitochondria
  • Oxidative Stress
  • Experimental Diabetes Mellitus
  • Aconitate Hydratase
  23 Scopus citations

• Exercise increases markers of spermatogenesis in rats selectively bred for low running capacity

  Torma, F., Koltai, E., Nagy, E., Ziaaldini, M. M., Posa, A., Koch, L. G., Britton, S. L., Boldogh, I. & Radak, Z., Dec 10 2014, In: PloS one. 9, 12, e11407.

  Research output: Contribution to journal › Article › peer-review

  • Rats
  • Spermatogenesis
  • Running
  • spermatogenesis
  • exercise
  13 Scopus citations

• Exposure to inhomogeneous static magnetic field beneficially affects allergic inflammation in a murine model

  Csillag, A., Kumar, B. V., Szabó, K., Szilasi, M., Papp, Z., Szilasi, M. E., Pázmándi, K., Boldogh, I., Rajnavölgyi, É., Bácsi, A. & László, J. F., Jun 6 2014, In: Journal of the Royal Society Interface. 11, 95, 20140097.

  Research output: Contribution to journal › Article › peer-review

  • Magnetic Fields
  • Magnetic fields
  • ragweed pollen
  • Inflammation
  • Reactive Oxygen Species
  12 Scopus citations

• Expression of 8-oxoguanine Glycosylase in Human Fetal Membranes

  Menon, R., Polettini, J., Syed, T. A., Saade, G. R. & Boldogh, I., Jan 1 2014, In: American Journal of Reproductive Immunology. 72, 1, p. 75-84 10 p.

  Research output: Contribution to journal › Article › peer-review

  • 8-hydroxyguanine
  • Extraembryonic Membranes
  • Smoke
  • Tobacco Products
  • Preterm Premature Rupture of the Membranes
  27 Scopus citations

• Histological evidence of oxidative stress and premature senescence in preterm premature rupture of the human fetal membranes recapitulated in vitro

  Menon, R., Boldogh, I., Hawkins, H. K., Woodson, M., Polettini, J., Syed, T. A., Fortunato, S. J., Saade, G. R., Papaconstantinou, J. & Taylor, R. N., Jun 2014, In: American Journal of Pathology. 184, 6, p. 1740-1751 12 p.

  Research output: Contribution to journal › Article › peer-review

  • Premature Rupture Fetal Membranes
  • Oxidative Stress
  • Membranes
  • Premature Birth
  • In Vitro Techniques
  111 Scopus citations

• Innate inflammation induced by the 8-oxoguanine DNA glycosylase-1-KRAS-NF-κB pathway

  Aguilera-Aguirre, L., Bacsi, A., Radak, Z., Hazra, T. K., Mitra, S., Sur, S., Brasier, A. R., Ba, X. & Boldogh, I., Nov 1 2014, In: Journal of Immunology. 193, 9, p. 4643-4653 11 p.

  Research output: Contribution to journal › Article › peer-review

  • 8-hydroxyguanine
  • DNA Glycosylases
  • Inflammation
  • DNA
  • 7,8-dihydro-8-oxoguanine
  60 Scopus citations

• NEIL2 Protects against Oxidative DNA damage induced by sidestream smoke in human cells

  Sarker, A. H., Chatterjee, A., Williams, M., Lin, S., Havel, C., Jacob, P., Boldogh, I., Hazra, T. K., Talbot, P. & Hang, B., Mar 3 2014, In: PloS one. 9, 3, e90261.

  Research output: Contribution to journal › Article › peer-review

  • smoke
  • DNA damage
  • Cells
  • Smoke
  • DNA Damage
  20 Scopus citations

• New perspectives on oxidized genome damage and repair inhibition by pro-oxidant metals in neurological diseases

  Mitra, J., Guerrero, E. N., Hegde, P. M., Wang, H., Boldogh, I., Rao, K. S., Mitra, S. & Hegde, M. L., Sep 1 2014, In: Biomolecules. 4, 3, p. 678-703 26 p.

  Research output: Contribution to journal › Review article › peer-review

  • Genes
  • Metals
  • Repair
  • Reactive Oxygen Species
  • Inhibition (Psychology)
  21 Scopus citations

• Oxidative modification enhances the immunostimulatory effects of extracellular mitochondrial DNA on plasmacytoid dendritic cells

  Pazmandi, K., Agod, Z., Kumar, B. V., Szabo, A., Fekete, T., Sogor, V., Veres, A., Boldogh, I., Rajnavolgyi, E., Lanyi, A. & Bacsi, A., 2014, In: Free Radical Biology and Medicine. 77, p. 281-290 10 p.

  Research output: Contribution to journal › Article › peer-review

  • Dendritic Cells
  • Mitochondrial DNA
  • Oxidative stress
  • Molecules
  • 8-hydroxyguanine
  28 Scopus citations

• Systems biology approaches to understanding epithelial mesenchymal transition (EMT) in mucosal remodeling and signaling in asthma

  Ijaz, T., Pazdrak, K., Kalita, M., Konig, R., Choudhary, S., Tian, B., Boldogh, I. & Brasier, A. R., Jun 2 2014, In: World Allergy Organization Journal. 7, 1, 13.

  Research output: Contribution to journal › Review article › peer-review

  • Systems Biology
  • Epithelial-Mesenchymal Transition
  • Asthma
  • Extracellular Matrix
  • Myofibroblasts
  55 Scopus citations

• The redox-associated adaptive response of brain to physical exercise

  Radak, Z., Ihasz, F., Koltai, E., Goto, S., Taylor, A. W. & Boldogh, I., Jan 1 2014, In: Free Radical Research. 48, 1, p. 84-92 9 p.

  Research output: Contribution to journal › Review article › peer-review

  • Oxidation-Reduction
  • Brain
  • Exercise
  • Reactive Oxygen Species
  • Metabolism
  30 Scopus citations

• The role of 8-oxoguanine DNA glycosylase-1 in inflammation

  Ba, X., Aguilera-Aguirre, L., Rashid, Q. T. A. N., Bacsi, A., Radak, Z., Sur, S., Hosoki, K., Hegde, M. L. & Boldogh, I., Sep 23 2014, In: International journal of molecular sciences. 15, 9, p. 16975-16997 23 p.

  Research output: Contribution to journal › Review article › peer-review

  • 8-hydroxyguanine
  • DNA Glycosylases
  • DNA
  • deoxyribonucleic acid
  • Inflammation
  52 Scopus citations
• 2013

  8-Oxoguanine DNA glycosylase-1 links DNA repair to cellular signaling via the activation of the small GTPase Rac1

  Hajas, G., Bacsi, A., Aguilera-Aguirre, L., Hegde, M. L., Tapas, K. H., Sur, S., Radak, Z., Ba, X. & Boldogh, I., 2013, In: Free Radical Biology and Medicine. 61, p. 384-394 11 p.

  Research output: Contribution to journal › Article › peer-review

  • Cell signaling
  • 8-hydroxyguanine
  • DNA Glycosylases
  • Monomeric GTP-Binding Proteins
  • DNA Repair
  58 Scopus citations

• Activation of cellular signaling by 8-oxoguanine DNA glycosylase-1-initiated DNA base excision repair

  German, P., Szaniszlo, P., Hajas, G., Radak, Z., Bacsi, A., Hazra, T. K., Hegde, M. L., Ba, X. & Boldogh, I., Oct 2013, In: DNA Repair. 12, 10, p. 856-863 8 p.

  Research output: Contribution to journal › Article › peer-review

  • Cell signaling
  • 8-hydroxyguanine
  • DNA Glycosylases
  • DNA Repair
  • Chemical activation
  46 Scopus citations

• Aerobic endurance capacity affects spatial memory and SIRT1 is a potent modulator of 8-oxoguanine repair

  Sarga, L., Hart, N., Koch, L. G., Britton, S. L., Hajas, G., Boldogh, I., Ba, X. & Radak, Z., Nov 12 2013, In: Neuroscience. 252, p. 326-336 11 p.

  Research output: Contribution to journal › Article › peer-review

  • 8-hydroxyguanine
  • DNA Glycosylases
  • Spatial Memory
  • Running
  • Post Translational Protein Processing
  18 Scopus citations

• Aldose Reductase Inhibition Prevents Allergic Airway Remodeling through PI3K/AKT/GSK3β Pathway in Mice

  Yadav, U. C. S., Naura, A. S., Aguilera-Aguirre, L., Boldogh, I., Boulares, H. A., Calhoun, W. J., Ramana, K. V. & Srivastava, S. K., Feb 27 2013, In: PloS one. 8, 2, e57442.

  Research output: Contribution to journal › Article › peer-review

  • Aldehyde Reductase
  • phosphatidylinositol 3-kinase
  • Airway Remodeling
  • Phosphatidylinositol 3-Kinases
  • mice
  27 Scopus citations

• Down-regulation of 8-oxoguanine DNA glycosylase 1 expression in the airway epithelium ameliorates allergic lung inflammation

  Bacsi, A., Aguilera-Aguirre, L., Szczesny, B., Radak, Z., Hazra, T. K., Sur, S., Ba, X. & Boldogh, I., Jan 1 2013, In: DNA Repair. 12, 1, p. 18-26 9 p.

  Research output: Contribution to journal › Article › peer-review

  • 8-hydroxyguanine
  • DNA Glycosylases
  • Pneumonia
  • Epithelium
  • Down-Regulation
  48 Scopus citations