Find Research Outputs

Search results

• 2020

  Enzymatically inactive OGG1 binds to DNA and steers base excision repair toward gene transcription

  Hao, W., Wang, J., Zhang, Y., Wang, C., Xia, L., Zhang, W., Zafar, M., Kang, J. Y., Wang, R., Ali Bohio, A., Pan, L., Zeng, X., Wei, M., Boldogh, I. & Ba, X., Jun 1 2020, In: FASEB Journal. 34, 6, p. 7427-7441 15 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • 8-hydroxyguanine
  • Transcription
  • DNA Repair
  • Genes
  • Repair
  1 Scopus citations

• Exercise, redox system and neurodegenerative diseases

  Quan, H., Koltai, E., Suzuki, K., Aguiar, A. S., Pinho, R., Boldogh, I., Berkes, I. & Radak, Z., Oct 1 2020, In: Biochimica et Biophysica Acta - Molecular Basis of Disease. 1866, 10, 165778.

  Research output: Contribution to journal › Review article › peer-review

  Open Access

  • Oxidation-Reduction
  • Neurodegenerative Diseases
  • Reactive Oxygen Species
  • Housekeeping
  • Brain-Derived Neurotrophic Factor

• Pervasive Genomic Damage in Experimental Intracerebral Hemorrhage: Therapeutic Potential of a Mechanistic-Based Carbon Nanoparticle

  Dharmalingam, P., Talakatta, G., Mitra, J., Wang, H., Derry, P. J., Nilewski, L. G., McHugh, E. A., Fabian, R. H., Mendoza, K., Vasquez, V., Hegde, P. M., Kakadiaris, E., Roy, T., Boldogh, I., Hegde, V. L., Mitra, S., Tour, J. M., Kent, T. A. & Hegde, M. L., Mar 24 2020, In: ACS Nano. 14, 3, p. 2827-2846 20 p.

  Research output: Contribution to journal › Article › peer-review

  • hemorrhages
  • Hemin
  • Nanoparticles
  • Carbon
  • Iron
  4 Scopus citations

• Poly(ADP-ribosyl)ation enhances HuR oligomerization and contributes to pro-inflammatory gene mRNA stabilization

  Ke, Y., Lv, X., Fu, X., Zhang, J., Bohio, A. A., Zeng, X., Hao, W., Wang, R., Boldogh, I. & Ba, X., 2020, (Accepted/In press) In: Cellular and Molecular Life Sciences.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Poly ADP Ribosylation
  • Poly (ADP-Ribose) Polymerase-1
  • Messenger RNA
  • Genes
  • MicroRNAs

• The systemic role of SIRT1 in exercise mediated adaptation

  Radak, Z., Suzuki, K., Posa, A., Petrovszky, Z., Koltai, E. & Boldogh, I., Aug 2020, In: Redox Biology. 35, 101467.

  Research output: Contribution to journal › Review article › peer-review

  Open Access

  • Muscle
  • Neurodegenerative diseases
  • Exercise
  • Liver
  • NAD
  2 Scopus citations
• 2019

  C-Abl-mediated tyrosine phosphorylation of PARP1 is crucial for expression of proinflammatory genes

  Bohio, A. A., Sattout, A., Wang, R., Wang, K., Sah, R. K., Guo, X., Zeng, X., Ke, Y., Boldogh, I. & Ba, X., Sep 15 2019, In: Journal of Immunology. 203, 6, p. 1521-1531 11 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Poly (ADP-Ribose) Polymerase-1
  • Tyrosine
  • Phosphorylation
  • Gene Expression
  • Poly ADP Ribosylation
  5 Scopus citations

• Epigenetic regulation of TIMP1 expression by 8-oxoguanine DNA glycosylase-1 binding to DNA:RNA hybrid

  Pan, L., Wang, H., Luo, J., Zeng, J., Pi, J., Liu, H., Liu, C., Ba, X., Qu, X., Xiang, Y., Boldogh, I. & Qin, X., Dec 1 2019, In: FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 33, 12, p. 14159-14170 12 p.

  Research output: Contribution to journal › Article › peer-review

  • 8-hydroxyguanine
  • DNA Glycosylases
  • Tissue Inhibitor of Metalloproteinase-1
  • Epigenomics
  • RNA

• Exercise and probiotics attenuate the development of Alzheimer's disease in transgenic mice: Role of microbiome

  Abraham, D., Feher, J., Scuderi, G. L., Szabo, D., Dobolyi, A., Cservenak, M., Juhasz, J., Ligeti, B., Pongor, S., Gomez-Cabrera, M. C., Vina, J., Higuchi, M., Suzuki, K., Boldogh, I. & Radak, Z., Jan 2019, In: Experimental Gerontology. 115, p. 122-131 10 p.

  Research output: Contribution to journal › Article › peer-review

  • Probiotics
  • Microbiota
  • Transgenic Mice
  • Alzheimer Disease
  • Amyloid
  30 Scopus citations

• Exercise effects on physiological function during aging

  Radak, Z., Torma, F., Berkes, I., Goto, S., Mimura, T., Posa, A., Balogh, L., Boldogh, I., Suzuki, K., Higuchi, M. & Koltai, E., Feb 20 2019, In: Free Radical Biology and Medicine. 132, p. 33-41 9 p.

  Research output: Contribution to journal › Review article › peer-review

  • Protease La
  • Aging of materials
  • Mitochondrial Degradation
  • Housekeeping
  • Exercise
  22 Scopus citations

• Motor neuron disease-associated loss of nuclear TDP-43 is linked to DNA double-strand break repair defects

  Mitra, J., Guerrero, E. N., Hegde, P. M., Liachko, N. F., Wang, H., Vasquez, V., Gao, J., Pandey, A., Paul Taylor, J., Kraemer, B. C., Wu, P., Boldogh, I., Garruto, R. M., Mitra, S., Rao, K. S. & Hegde, M. L., 2019, In: Proceedings of the National Academy of Sciences of the United States of America. 116, 10, p. 4696-4705 10 p.

  Research output: Contribution to journal › Article › peer-review

  • Motor Neuron Disease
  • Double-Stranded DNA Breaks
  • DNA Damage
  • Amyotrophic lateral sclerosis 1
  • DNA-Binding Proteins
  43 Scopus citations

• Oxidized base 8-oxoguanine, a product of DNA repair processes, contributes to dendritic cell activation

  Pázmándi, K., Sütő, M., Fekete, T., Varga, A., Boldizsár, E., Boldogh, I. & Bácsi, A., Nov 1 2019, In: Free Radical Biology and Medicine. 143, p. 209-220 12 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Dendritic Cells
  • 8-hydroxyguanine
  • DNA Glycosylases
  • DNA Repair
  • Chemical activation
  3 Scopus citations

• Roles of DNA repair enzyme OGG1 in innate immunity and its significance for lung cancer

  Vlahopoulos, S., Adamaki, M., Khoury, N., Zoumpourlis, V. & Boldogh, I., Feb 2019, In: Pharmacology and Therapeutics. 194, p. 59-72 14 p.

  Research output: Contribution to journal › Review article › peer-review

  • DNA Repair Enzymes
  • Oxidants
  • Innate Immunity
  • Lung Neoplasms
  • Cytokines
  12 Scopus citations

• Targeting inducible epigenetic reprogramming pathways in chronic airway remodeling

  Brasier, A. R. & Boldogh, I., 2019, In: Drugs in Context. 8, 2019-8-3.

  Research output: Contribution to journal › Review article › peer-review

  Open Access

  • Airway Remodeling
  • Epigenomics
  • Toll-Like Receptors
  • Inflammation
  • 8-hydroxyguanine
• 2018

  Effects of the stimuli-dependent enrichment of 8-oxoguanine DNA glycosylase1 on chromatinized DNA

  Hao, W., Qi, T., Pan, L., Wang, R., Zhu, B., Aguilera-Aguirre, L., Radak, Z., Hazra, T. K., Vlahopoulos, S. A., Bacsi, A., Brasier, A. R., Ba, X. & Boldogh, I., Sep 2018, In: Redox Biology. 18, p. 43-53 11 p.

  Research output: Contribution to journal › Article › peer-review

  • 8-hydroxyguanine
  • DNA Glycosylases
  • DNA
  • Genes
  • Gene Expression
  14 Scopus citations

• Excision release of 5?hydroxycytosine oxidatively induced DNA base lesions from the lung genome by cat dander extract challenge stimulates allergic airway inflammation

  Hosoki, K., Jaruga, P., Itazawa, T., Aguilera-Aguirre, L., Coskun, E., Hazra, T. K., Boldogh, I., Dizdaroglu, M. & Sur, S., Dec 2018, In: Clinical and Experimental Allergy. 48, 12, p. 1676-1687 12 p.

  Research output: Contribution to journal › Article › peer-review

  • Dander
  • Cats
  • hydroxide ion
  • Genome
  • Inflammation
  1 Scopus citations

• Master athletes have higher miR-7, SIRT3 and SOD2 expression in skeletal muscle than age-matched sedentary controls

  Koltai, E., Bori, Z., Osvath, P., Ihasz, F., Peter, S., Toth, G., Degens, H., Rittweger, J., Boldogh, I. & Radak, Z., Oct 2018, In: Redox Biology. 19, p. 46-51 6 p.

  Research output: Contribution to journal › Article › peer-review

  • Muscle
  • Athletes
  • Skeletal Muscle
  • Muscles
  • Quadriceps Muscle
  14 Scopus citations

• OGG1-initiated base excision repair exacerbates oxidative stress-induced parthanatos

  Wang, R., Li, C., Qiao, P., Xue, Y., Zheng, X., Chen, H., Zeng, X., Liu, W., Boldogh, I. & Ba, X., Jun 1 2018, In: Cell Death and Disease. 9, 6, 628.

  Research output: Contribution to journal › Article › peer-review

  • Poly (ADP-Ribose) Polymerase-1
  • DNA Repair
  • Cell Death
  • Oxidative Stress
  • 8-hydroxyguanine
  17 Scopus citations

• Small-molecule inhibitor of OGG1 suppresses proinflammatory gene expression and inflammation

  Visnes, T., Cázares-Körner, A., Hao, W., Wallner, O., Masuyer, G., Loseva, O., Mortusewicz, O., Wiita, E., Sarno, A., Manoilov, A., Astorga-Wells, J., Jemth, A. S., Pan, L., Sanjiv, K., Karsten, S., Gokturk, C., Grube, M., Homan, E. J., Hanna, B. M. F., Paulin, C. B. J. & 20 others, Pham, T., Rasti, A., Berglund, U. W., Von Nicolai, C., Benitez-Buelga, C., Koolmeister, T., Ivanic, D., Iliev, P., Scobie, M., Krokan, H. E., Baranczewski, P., Artursson, P., Altun, M., Jensen, A. J., Kalderén, C., Ba, X., Zubarev, R. A., Stenmark, P., Boldogh, I. & Helleday, T., Nov 16 2018, In: Science. 362, 6416, p. 834-839 6 p.

  Research output: Contribution to journal › Article › peer-review

  • DNA Glycosylases
  • Gene Expression
  • Inflammation
  • 7,8-dihydro-8-oxoguanine
  • DNA
  36 Scopus citations

• The establishment of methods for free PAR generation and PAR reader detection

  Ke, Y., Wang, K., Xu, H., Wang, C., Zhang, J., Zeng, X., Wang, R., Boldogh, I. & Ba, X., Jan 1 2018, (Accepted/In press) In: Molecular and Cellular Probes.

  Research output: Contribution to journal › Article › peer-review

  • Poly (ADP-Ribose) Polymerase-1
  • Proteins
  • 1,2-di-(4-sulfamidophenyl)-4-butylpyrazolidine-3,5-dione
  • Poly Adenosine Diphosphate Ribose
  • NAD
  1 Scopus citations

• The roles of base excision repair enzyme OGG1 in gene expression

  Wang, R., Hao, W., Pan, L., Boldogh, I. & Ba, X., Oct 1 2018, In: Cellular and Molecular Life Sciences. 75, 20, p. 3741-3750 10 p.

  Research output: Contribution to journal › Review article › peer-review

  • 8-hydroxyguanine
  • DNA Repair
  • Gene Expression
  • DNA
  • Enzymes
  19 Scopus citations
• 2017

  8-Oxoguanine DNA glycosylase1–driven DNA repair—A paradoxical role in lung aging

  German, P., Saenz, D., Szaniszlo, P., Aguilera-Aguirre, L., Pan, L., Hegde, M. L., Bacsi, A., Hajas, G., Radak, Z., Ba, X., Mitra, S., Papaconstantinou, J. & Boldogh, I., Jan 1 2017, In: Mechanisms of Ageing and Development. 161, p. 51-65 15 p.

  Research output: Contribution to journal › Article › peer-review

  • 8-hydroxyguanine
  • DNA Repair
  • Cultured Cells
  • DNA
  • Lung
  9 Scopus citations

• Chronic oxidative damage together with genome repair deficiency in the neurons is a double whammy for neurodegeneration: Is damage response signaling a potential therapeutic target?

  Wang, H., Dharmalingam, P., Vasquez, V., Mitra, J., Boldogh, I., Rao, K. S., Kent, T. A., Mitra, S. & Hegde, M. L., Jan 1 2017, In: Mechanisms of Ageing and Development. 161, p. 163-176 14 p.

  Research output: Contribution to journal › Review article › peer-review

  • DNA Damage
  • Genome
  • Neurons
  • Reactive Oxygen Species
  • Neurodegenerative Diseases
  10 Scopus citations

• Erratum: PARP1 promotes gene expression at the post-transcriptional level by modulating the RNA-binding protein HuR

  Ke, Y., Han, Y., Guo, X., Wen, J., Wang, K., Jiang, X., Tian, X., Ba, X., Boldogh, I. & Zeng, X., Mar 31 2017, In: Nature communications. 8, p. 15191 1 p., 15191.

  Research output: Contribution to journal › Article › peer-review
  4 Scopus citations

• Exercise, oxidants, and antioxidants change the shape of the bell-shaped hormesis curve

  Radak, Z., Ishihara, K., Tekus, E., Varga, C., Posa, A., Balogh, L., Boldogh, I. & Koltai, E., Aug 1 2017, In: Redox Biology. 12, p. 285-290 6 p.

  Research output: Contribution to journal › Short survey › peer-review

  • Hormesis
  • Normal distribution
  • Oxidants
  • Antioxidants
  • Oxidative stress
  64 Scopus citations

• Exogenous nicotinamide supplementation and moderate physical exercise can attenuate the aging process in skeletal muscle of rats

  Pajk, M., Cselko, A., Varga, C., Posa, A., Tokodi, M., Boldogh, I., Goto, S. & Radak, Z., Aug 1 2017, In: Biogerontology. 18, 4, p. 593-600 8 p.

  Research output: Contribution to journal › Article › peer-review

  • Niacinamide
  • Skeletal Muscle
  • Exercise
  • Running
  • NAD
  10 Scopus citations

• Innate mechanism of pollen- and cat dander–induced oxidative stress and DNA damage in the airways

  Hosoki, K., Redding, D., Itazawa, T., Chakraborty, A., Tapryal, N., Qian, S., Qi, H., Aguilera-Aguirre, L., Brasier, A. R., Phani, V. S., Hazra, T. K., Boldogh, I. & Sur, S., Nov 2017, In: Journal of Allergy and Clinical Immunology. 140, 5, p. 1436-1439.e5

  Research output: Contribution to journal › Article › peer-review
  6 Scopus citations

• NF-κB mediates mesenchymal transition, remodeling, and pulmonary fibrosis in response to chronic inflammation by viral RNA patterns

  Tian, B., Patrikeev, I., Ochoa, L., Vargas, G., Belanger, K. A. K., Litvinov, J., Boldogh, I., Ameredes, B. T., Motamedi, M. & Brasier, A. R., Apr 2017, In: American journal of respiratory cell and molecular biology. 56, 4, p. 506-520 15 p.

  Research output: Contribution to journal › Article › peer-review

  • Poly I-C
  • Pulmonary Fibrosis
  • Viral RNA
  • Airway Remodeling
  • 4(2'-aminoethyl)amino-1,8-dimethylimidazo(1,2-a)quinoxaline
  25 Scopus citations

• OGG1-DNA interactions facilitate NF-k B binding to DNA targets

  Pan, L., Hao, W., Zheng, X., Zeng, X., Ahmed Abbasi, A., Boldogh, I. & Ba, X., Mar 7 2017, In: Scientific reports. 7, 43297.

  Research output: Contribution to journal › Article › peer-review

  • 8-oxo-7-hydrodeoxyguanosine
  • DNA
  • DNA Repair
  • Gene Expression
  • Guanine
  17 Scopus citations

• PARP1 promotes gene expression at the post-transcriptiona level by modulating the RNA-binding protein HuR

  Ke, Y., Han, Y., Guo, X., Wen, J., Wang, K., Jiang, X., Tian, X., Ba, X., Boldogh, I. & Zeng, X., Mar 8 2017, In: Nature communications. 8, 14632.

  Research output: Contribution to journal › Article › peer-review

  • ribose
  • Poly ADP Ribosylation
  • Poly (ADP-Ribose) Polymerase-1
  • gene expression
  • adenosine diphosphate
  23 Scopus citations

• Pollen-induced oxidative DNA damage response regulates miRNAs controlling allergic inflammation

  Aguilera-Aguirre, L., Hao, W., Pan, L., Li, X., Saavedra-Molina, A., Bacsi, A., Radak, Z., Sur, S., Brasier, A. R., Ba, X. & Boldogh, I., Dec 2017, In: American Journal of Physiology - Lung Cellular and Molecular Physiology. 313, 6, p. L1058-L1068

  Research output: Contribution to journal › Article › peer-review

  • DNA Glycosylases
  • Pollen
  • DNA Damage
  • MicroRNAs
  • 8-hydroxyguanine
  5 Scopus citations

• Regulation of type I interferon responses by mitochondria-derived reactive oxygen species in plasmacytoid dendritic cells

  Agod, Z., Fekete, T., Budai, M. M., Varga, A., Szabo, A., Moon, H., Boldogh, I., Biro, T., Lanyi, A., Bacsi, A. & Pazmandi, K., Oct 2017, In: Redox Biology. 13, p. 633-645 13 p.

  Research output: Contribution to journal › Article › peer-review

  • Dendritic Cells
  • Mitochondria
  • Interferon Type I
  • Reactive Oxygen Species
  • Tretinoin
  13 Scopus citations

• Reply: Protease plays a role in ragweed pollen-induced neutrophil recruitment and epithelial barrier disruption

  Hosoki, K., Brasier, A. R., Kurosky, A., Boldogh, I. & Sur, S., Feb 1 2017, In: American Journal of Respiratory Cell and Molecular Biology. 56, 2, p. 272-273 2 p.

  Research output: Contribution to journal › Letter › peer-review
  1 Scopus citations

• SIRT1 may play a crucial role in overload-induced hypertrophy of skeletal muscle

  Koltai, E., Bori, Z., Chabert, C., Dubouchaud, H., Naito, H., Machida, S., Davies, K. J. A., Murlasits, Z., Fry, A. C., Boldogh, I. & Radak, Z., Jun 1 2017, In: Journal of Physiology. 595, 11, p. 3361-3376 16 p.

  Research output: Contribution to journal › Article › peer-review

  • Hypertrophy
  • Skeletal Muscle
  • Muscles
  • Nicotinamide Phosphoribosyltransferase
  • Sirtuin 1
  18 Scopus citations
• 2015

  17-beta estradiol inhibits oxidative stress-induced accumulation of AIF into nucleolus and PARP1-dependent cell death via estrogen receptor alpha

  Batnasan, E., Wang, R., Wen, J., Ke, Y., Li, X., Bohio, A. A., Zeng, X., Huo, H., Han, L., Boldogh, I. & Ba, X., Jan 5 2015, In: Toxicology Letters. 232, 1, p. 1-9 9 p.

  Research output: Contribution to journal › Article › peer-review

  • Oxidative stress
  • Cell death
  • Poly (ADP-Ribose) Polymerase-1
  • Estrogen Receptor alpha
  • Estradiol
  14 Scopus citations

• 8-Oxoguanine DNA glycosylase-1-driven DNA base excision repair: Role in asthma pathogenesis

  Ba, X., Aguilera-Aguirre, L., Sur, S. & Boldogh, I., Feb 13 2015, In: Current opinion in allergy and clinical immunology. 15, 1, p. 89-97 9 p.

  Research output: Contribution to journal › Review article › peer-review

  • 8-hydroxyguanine
  • DNA Glycosylases
  • DNA Repair
  • Asthma
  • DNA
  17 Scopus citations

• Analysis of a panel of 48 cytokines in BAL fluids specifically identifies IL-8 levels as the only cytokine that distinguishes controlled asthma from uncontrolled asthma, and correlates inversely with FEV₁

  Hosoki, K., Ying, S., Corrigan, C., Qi, H., Kurosky, A., Jennings, K., Sun, Q., Boldogh, I. & Sur, S., May 2015, In: PloS one. 10, 5, e0126035.

  Research output: Contribution to journal › Article › peer-review

  • interleukin-8
  • asthma
  • Bronchoalveolar Lavage Fluid
  • Interleukin-8
  • cytokines
  47 Scopus citations

• Ataxia telangiectasia mutated kinase mediates NF-κB serine 276 phosphorylation and interferon expression via the IRF7-RIG-I amplification loop in paramyxovirus infection

  Fang, L., Choudhary, S., Tian, B., Boldogh, I., Yang, C., Ivanciuc, T., Ma, Y., Garofalo, R. P. & Brasier, A. R., Jan 1 2015, In: Journal of virology. 89, 5, p. 2628-2642 15 p.

  Research output: Contribution to journal › Article › peer-review

  • Respirovirus
  • Factor VII
  • Ataxia Telangiectasia
  • retinoic acid
  • Gene Amplification
  20 Scopus citations

• BRG1 promotes the repair of DNA double-strand breaks by facilitating the replacement of RPA with RAD51

  Qi, W., Wang, R., Chen, H., Wang, X., Xiao, T., Boldogh, I., Ba, X., Han, L. & Zeng, X., 2015, In: Journal of Cell Science. 128, 2, p. 317-330 14 p.

  Research output: Contribution to journal › Article › peer-review

  • Recombinational DNA Repair
  • Double-Stranded DNA Breaks
  • Single-Stranded DNA
  • Chromatin Assembly and Disassembly
  • Switch Genes
  45 Scopus citations

• Dynamic aberrant NF-κB spurs tumorigenesis: A new model encompassing the microenvironment

  Vlahopoulos, S. A., Cen, O., Hengen, N., Agan, J., Moschovi, M., Critselis, E., Adamaki, M., Bacopoulou, F., Copland, J. A., Boldogh, I., Karin, M. & Chrousos, G. P., Aug 1 2015, In: Cytokine and Growth Factor Reviews. 26, 4, p. 389-403 15 p.

  Research output: Contribution to journal › Review article › peer-review

  • Tissue
  • Carcinogenesis
  • Stem cells
  • Tumors
  • Oncogenes
  57 Scopus citations

• Exercise training increases anabolic and attenuates catabolic and apoptotic processes in aged skeletal muscle of male rats

  Ziaaldini, M. M., Koltai, E., Csende, Z., Goto, S., Boldogh, I., Taylor, A. W. & Radak, Z., Jul 1 2015, In: Experimental Gerontology. 67, p. 9-14 6 p.

  Research output: Contribution to journal › Article › peer-review

  • Rats
  • Muscle
  • Skeletal Muscle
  • Exercise
  • Chemical activation
  43 Scopus citations

• Genetic Evidence for XPC-KRAS Interactions During Lung Cancer Development

  Zhang, X., He, N., Gu, D., Wickliffe, J., Salazar, J., Boldogh, I. & Xie, J., Oct 20 2015, In: Journal of Genetics and Genomics. 42, 10, p. 589-596 8 p.

  Research output: Contribution to journal › Article › peer-review

  • Xeroderma Pigmentosum
  • Lung Neoplasms
  • DNA Damage
  • Reactive Oxygen Species
  • DNA Repair-Deficiency Disorders
  4 Scopus citations

• Innate responses to pollen allergens

  Hosoki, K., Boldogh, I. & Sur, S., Feb 13 2015, In: Current opinion in allergy and clinical immunology. 15, 1, p. 79-88 10 p.

  Research output: Contribution to journal › Review article › peer-review

  • Pollen
  • Allergens
  • Innate Immunity
  • NADP
  • Oxidoreductases
  17 Scopus citations

• Mitochondrial biogenesis-associated factors underlie the magnitude of response to aerobic endurance training in rats

  Marton, O., Koltai, E., Takeda, M., Koch, L. G., Britton, S. L., Davies, K. J. A., Boldogh, I. & Radak, Z., Jan 1 2015, In: Pflugers Archiv European Journal of Physiology. 467, 4, p. 779-788 10 p.

  Research output: Contribution to journal › Article › peer-review

  • Organelle Biogenesis
  • Endurance Training
  • Rats
  • Mitochondrial Dynamics
  • Durability
  22 Scopus citations

• Neil2-null mice accumulate oxidized DNA bases in the transcriptionally active sequences of the genome and are susceptible to innate inflammation

  Chakraborty, A., Wakamiya, M., Venkova-Canova, T., Pandita, R. K., Aguilera-Aguirre, L., Sarker, A. H., Singh, D. K., Hosoki, K., Wood, T. G., Sharma, G., Cardenas, V., Sarkar, P. S., Sur, S., Pandita, T. K., Boldogh, I. & Hazra, T. K., Oct 9 2015, In: Journal of Biological Chemistry. 290, 41, p. 24636-24648 13 p.

  Research output: Contribution to journal › Article › peer-review

  • DNA Glycosylases
  • Mammals
  • Genes
  • Repair
  • Genome
  35 Scopus citations

• Oxidative stress damage-associated molecular signaling pathways differentiate spontaneous preterm birth and preterm premature rupture of the membranes

  Dutta, E. H., Behnia, F., Boldogh, I., Saade, G., Taylor, B. D., Kacerovský, M. & Menon, R., Aug 28 2015, In: Molecular Human Reproduction. 22, 2, p. 143-157 15 p., gav074.

  Research output: Contribution to journal › Article › peer-review

  • Preterm Premature Rupture of the Membranes
  • Premature Birth
  • Oxidative Stress
  • Extraembryonic Membranes
  • ras Proteins
  74 Scopus citations

• The C-terminal domain (CTD) of human DNA glycosylase NEIL1 is required for forming BERosome repair complex with DNA replication proteins at the replicating genome: Dominant negative function of the CTD

  Hegde, P. M., Dutta, A., Sengupta, S., Mitra, J., Adhikari, S., Tomkinson, A. E., Li, G. M., Boldogh, I., Hazra, T. K., Mitra, S. & Hegde, M. L., Aug 21 2015, In: Journal of Biological Chemistry. 290, 34, p. 20919-20933 15 p.

  Research output: Contribution to journal › Article › peer-review

  • DNA Glycosylases
  • DNA Replication
  • DNA Repair
  • Genes
  • Repair
  24 Scopus citations

• The Role of the Mammalian DNA End-processing Enzyme Polynucleotide Kinase 3’-Phosphatase in Spinocerebellar Ataxia Type 3 Pathogenesis

  Chatterjee, A., Saha, S., Chakraborty, A., Silva-Fernandes, A., Mandal, S. M., Neves-Carvalho, A., Liu, Y., Pandita, R. K., Hegde, M. L., Hegde, P. M., Boldogh, I., Ashizawa, T., Koeppen, A. H., Pandita, T. K., Maciel, P., Sarkar, P. S. & Hazra, T. K., 2015, In: PLoS genetics. 11, 1, e1004749.

  Research output: Contribution to journal › Article › peer-review

  • Polynucleotide 5'-Hydroxyl-Kinase
  • Machado-Joseph Disease
  • polynucleotides
  • phosphatase
  • Ataxin-3
  44 Scopus citations

• Whole transcriptome analysis reveals an 8-oxoguanine DNA glycosylase-1-driven DNA repair-dependent gene expression linked to essential biological processes

  Aguilera-Aguirre, L., Hosoki, K., Bacsi, A., Radák, Z., Wood, T. G., Widen, S. G., Sur, S., Ameredes, B. T., Saavedra-Molina, A., Brasier, A. R., Ba, X. & Boldogh, I., Apr 2015, In: Free Radical Biology and Medicine. 81, p. 107-118 12 p.

  Research output: Contribution to journal › Article › peer-review

  • 8-hydroxyguanine
  • DNA Glycosylases
  • Gene expression
  • Gene Expression Profiling
  • Biological Phenomena
  25 Scopus citations

• Whole transcriptome analysis reveals a role for OGG1-initiated DNA repair signaling in airway remodeling

  Aguilera-Aguirre, L., Hosoki, K., Bacsi, A., Radák, Z., Sur, S., Hegde, M. L., Tian, B., Saavedra-Molina, A., Brasier, A. R., Ba, X. & Boldogh, I., Dec 1 2015, In: Free Radical Biology and Medicine. 89, p. 20-33 14 p.

  Research output: Contribution to journal › Article › peer-review

  • 8-hydroxyguanine
  • DNA Glycosylases
  • Airway Remodeling
  • Gene Expression Profiling
  • DNA Repair
  23 Scopus citations
• 2013

  8-Oxoguanine DNA glycosylase-1 links DNA repair to cellular signaling via the activation of the small GTPase Rac1

  Hajas, G., Bacsi, A., Aguilera-Aguirre, L., Hegde, M. L., Tapas, K. H., Sur, S., Radak, Z., Ba, X. & Boldogh, I., 2013, In: Free Radical Biology and Medicine. 61, p. 384-394 11 p.

  Research output: Contribution to journal › Article › peer-review

  • Cell signaling
  • 8-hydroxyguanine
  • DNA Glycosylases
  • Monomeric GTP-Binding Proteins
  • DNA Repair
  58 Scopus citations